LOCUS       NM_001109040            6443 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus kinesin family member 21A (Kif21a), transcript variant
            1, mRNA.
ACCESSION   NM_001109040
VERSION     NM_001109040.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6443)
  AUTHORS   Cesari,E., Farini,D., Medici,V., Ehrmann,I., Guerra,M., Testa,E.,
            Naro,C., Geloso,M.C., Pagliarini,V., La Barbera,L., D'Amelio,M.,
            Orsini,T., Vecchioli,S.F., Tamagnone,L., Fort,P., Viscomi,M.T.,
            Elliott,D.J. and Sette,C.
  TITLE     Differential expression of paralog RNA binding proteins establishes
            a dynamic splicing program required for normal cerebral cortex
            development
  JOURNAL   Nucleic Acids Res 52 (8), 4167-4184 (2024)
   PUBMED   38324473
REFERENCE   2  (bases 1 to 6443)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 6443)
  AUTHORS   Xu,Y., Guo,C., Pan,W., Zhao,C., Ding,Y., Xie,X., Wei,Z., Sun,Y. and
            Yu,C.
  TITLE     Nephrotic-syndrome-associated mutation of KANK2 induces pathologic
            binding competition with physiological interactor KIF21A
  JOURNAL   J Biol Chem 297 (2), 100958 (2021)
   PUBMED   34274317
  REMARK    GeneRIF: Nephrotic-syndrome-associated mutation of KANK2 induces
            pathologic binding competition with physiological interactor
            KIF21A.
REFERENCE   4  (bases 1 to 6443)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6443)
  AUTHORS   Farini,D., Cesari,E., Weatheritt,R.J., La Sala,G., Naro,C.,
            Pagliarini,V., Bonvissuto,D., Medici,V., Guerra,M., Di Pietro,C.,
            Rizzo,F.R., Musella,A., Carola,V., Centonze,D., Blencowe,B.J.,
            Marazziti,D. and Sette,C.
  TITLE     A Dynamic Splicing Program Ensures Proper Synaptic Connections in
            the Developing Cerebellum
  JOURNAL   Cell Rep 31 (9), 107703 (2020)
   PUBMED   32492419
REFERENCE   6  (bases 1 to 6443)
  AUTHORS   Chan,W.M., Andrews,C., Dragan,L., Fredrick,D., Armstrong,L.,
            Lyons,C., Geraghty,M.T., Hunter,D.G., Yazdani,A., Traboulsi,E.I.,
            Pott,J.W., Gutowski,N.J., Ellard,S., Young,E., Hanisch,F., Koc,F.,
            Schnall,B. and Engle,E.C.
  TITLE     Three novel mutations in KIF21A highlight the importance of the
            third coiled-coil stalk domain in the etiology of CFEOM1
  JOURNAL   BMC Genet 8, 26 (2007)
   PUBMED   17511870
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6443)
  AUTHORS   Yamada,K., Andrews,C., Chan,W.M., McKeown,C.A., Magli,A., de
            Berardinis,T., Loewenstein,A., Lazar,M., O'Keefe,M., Letson,R.,
            London,A., Ruttum,M., Matsumoto,N., Saito,N., Morris,L., Del
            Monte,M., Johnson,R.H., Uyama,E., Houtman,W.A., de Vries,B.,
            Carlow,T.J., Hart,B.L., Krawiecki,N., Shoffner,J., Vogel,M.C.,
            Katowitz,J., Goldstein,S.M., Levin,A.V., Sener,E.C., Ozturk,B.T.,
            Akarsu,A.N., Brodsky,M.C., Hanisch,F., Cruse,R.P., Zubcov,A.A.,
            Robb,R.M., Roggenkaemper,P., Gottlob,I., Kowal,L., Battu,R.,
            Traboulsi,E.I., Franceschini,P., Newlin,A., Demer,J.L. and
            Engle,E.C.
  TITLE     Heterozygous mutations of the kinesin KIF21A in congenital fibrosis
            of the extraocular muscles type 1 (CFEOM1)
  JOURNAL   Nat Genet 35 (4), 318-321 (2003)
   PUBMED   14595441
REFERENCE   8  (bases 1 to 6443)
  AUTHORS   Miki,H., Setou,M., Kaneshiro,K. and Hirokawa,N.
  TITLE     All kinesin superfamily protein, KIF, genes in mouse and human
  JOURNAL   Proc Natl Acad Sci U S A 98 (13), 7004-7011 (2001)
   PUBMED   11416179
  REMARK    Review article
REFERENCE   9  (bases 1 to 6443)
  AUTHORS   Vadasz,C., Saito,M., Balla,A., Kiraly,I., Vadasz,C. 2nd,
            Gyetvai,B., Mikics,E., Pierson,D., Brown,D. and Nelson,J.C.
  TITLE     Mapping of quantitative trait loci for ethanol preference in
            quasi-congenic strains
  JOURNAL   Alcohol 20 (2), 161-171 (2000)
   PUBMED   10719795
REFERENCE   10 (bases 1 to 6443)
  AUTHORS   Marszalek,J.R., Weiner,J.A., Farlow,S.J., Chun,J. and
            Goldstein,L.S.
  TITLE     Novel dendritic kinesin sorting identified by different process
            targeting of two related kinesins: KIF21A and KIF21B
  JOURNAL   J Cell Biol 145 (3), 469-479 (1999)
   PUBMED   10225949
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK019525.1, BY714299.1, AK163536.1, BC062896.1, AK049303.1,
            AK147436.1, AK053373.1, AK052821.1 and AC136003.10.
            
            On Oct 23, 2013 this sequence version replaced NM_001109040.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164139
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AK019525.1         2-4
            4-117               BY714299.1         1-114
            118-1999            AK163536.1         2-1883
            2000-3926           BC062896.1         1828-3754
            3927-4034           AK049303.1         296-403
            4035-4202           AK147436.1         3776-3943
            4203-5887           AK147436.1         3959-5643
            5888-6429           AK053373.1         829-1370
            6430-6442           AK052821.1         1185-1197
            6443-6443           AC136003.10        65522-65522
FEATURES             Location/Qualifiers
     source          1..6443
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 45.86 cM"
     gene            1..6443
                     /gene="Kif21a"
                     /note="kinesin family member 21A"
                     /db_xref="GeneID:16564"
                     /db_xref="MGI:MGI:109188"
     exon            1..293
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     CDS             250..5268
                     /gene="Kif21a"
                     /note="isoform 1 is encoded by transcript variant 1;
                     kinesin-like protein KIF21A; N-5 kinesin"
                     /codon_start=1
                     /product="kinesin-like protein KIF21A isoform 1"
                     /protein_id="NP_001102510.1"
                     /db_xref="CCDS:CCDS49708.1"
                     /db_xref="GeneID:16564"
                     /db_xref="MGI:MGI:109188"
                     /translation="MLGAADESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLG
                     KDKAFTFDYVFDIDSQQEQIYTQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGF
                     DVNIMEEEQGIISRAVRHLFKSIDEKKTSAIKNGLPPPEFKVNAQFLELYNEEVLDLF
                     DTTRDIDAKNKKSNIRIHEDSTGGIYTVGVTTRTVNTEPEMMQCLKLGALSRTTASTQ
                     MNVQSSRSHAIFTIHVCQTRVCPQTDAENATDNKLISESSPMNEFETLTAKFHFVDLA
                     GSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQD
                     SLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSE
                     ITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALR
                     ARITQLVSEQANQVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLT
                     RATARSPYFSASSAFSPTILSSDKETIEIIDLAKKDLEKLKRKEKKKKKRLQKLEESG
                     REERSVAGKDDNADTDQEKKEEKGVSEKENNELDVEENQEVSDHEDEEEEEEDEEEED
                     DIEGEESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEE
                     KLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVKCEYEKKLHAMNKELQRLQTA
                     QKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIA
                     QLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSS
                     SESPAPDTGSSAASGEADTSRPGTQQKMRIPVARVQALPTPTTNGTRKKYQRKGFTGR
                     VFTSKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLRQREELTKRREKLSKRREK
                     IVKESGEGDKSVANIIEEMESLTANIDYINDSIADCQANIMQMEEAKEEGETLDVTAV
                     INACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHM
                     LKEKAELNPELDALLGHALQDLDGAPPENEEDSSEEDGPLHSPGSEGSTLSSDLMKLC
                     GEVKPKNKARRRTTTQMELLYADSSEVASDTSAGDASLSGPLAPVAEGQEIGMNTETS
                     GTSARDKELLAPSGLPSKIGSISRQSSLSEKKVPEPSPVTRRKAYEKADKPKAKEHKH
                     SDSGASETSLSPPSSPPSRPRNELNVFNRLTVPQGTPSVQQDKSDESDSSLSEVHRGI
                     INPFPACKGVRASPLQCVHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEI
                     MSLGVHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRESAKCIRTLTSSGQVTLGEACS
                     ASTSRTVAIPSGESQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVM
                     CLTVDQISNGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALAIQGD
                     NLFSGSRDNGIKKWDLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILKLWN
                     VDTFVPVGEMRGHDSPINAICVNSTHVFTAADDRTVRIWKAHNLQDGQLSDTGDLGED
                     IASN"
     exon            294..516
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            517..699
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            700..849
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            850..984
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1152
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1268
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            1269..1464
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            1465..1654
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            1655..1718
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            1719..1922
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            1923..1961
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            1962..2052
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            2053..2176
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            2177..2365
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            2366..2565
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            2566..2673
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            2674..2742
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            2743..2957
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            2958..3111
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            3112..3306
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            3307..3408
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            3409..3574
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            3575..3595
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            3596..3656
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            3657..3711
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            3712..3926
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            3927..4034
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            4035..4163
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            4164..4202
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            4203..4339
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            4340..4520
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            4521..4685
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            4686..4803
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            4804..4974
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            4975..5174
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     exon            5175..6443
                     /gene="Kif21a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5403..5408
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif21a"
                     /note="hexamer: AATAAA"
     polyA_site      5423
                     /gene="Kif21a"
     regulatory      6413..6418
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif21a"
                     /note="hexamer: AATAAA"
     polyA_site      6431
                     /gene="Kif21a"
                     /note="major polyA site"
ORIGIN      
        1 accggaccgg ccacggctga cgcagggcag cgcggagcct ggcgagtggg ggcaaggggc
       61 ggcgccgccc tgagtcaccg ccccctcccg cgcctccgcg ccgccacctt tccattcagt
      121 cgcccaacat ggctggagca cggcgctgag ccctcgccac cgtcaccgtc accgccgccg
      181 ccgccgtcac caccgccgcc gcctgcccgg agcgctcggc acggagctga gccccgggcg
      241 gccgcaggca tgttgggcgc tgcggacgag agctcggtgc gcgtggctgt cagaataaga
      301 ccacagcttg ccaaagagaa gatcgaaggt tgccatatct gcacgtcagt cacaccggga
      361 gagcctcagg tcttcctcgg gaaggataag gcctttactt ttgattatgt gtttgacatt
      421 gactcccagc aggagcagat ctacacccag tgcatcgaaa agctcattga aggctgtttt
      481 gaaggctaca atgccaccgt gtttgcctat ggacaaaccg gagctgggaa aacctacacg
      541 atgggaaccg gatttgacgt gaacatcatg gaggaagagc agggcatcat ctctcgtgct
      601 gttagacacc tgttcaagag tattgatgag aaaaagacct cagcgattaa aaacgggctg
      661 ccccctcctg aattcaaagt gaatgcccag ttcctagagc tctataatga agaggtcctt
      721 gacttgtttg ataccactcg ggatattgat gcaaaaaata aaaaatcaaa tataagaatt
      781 catgaagatt caactggagg aatttatact gtgggcgtca caacacgcac tgtgaataca
      841 gaaccggaga tgatgcagtg tctgaagctg ggcgctctct cgcgcaccac ggccagcacc
      901 cagatgaacg tacagagctc tcgttcacac gccatcttta ccattcacgt gtgtcaaacc
      961 agagtgtgtc cccaaacaga tgctgagaac gcaactgata ataagctgat ctccgaatcg
     1021 tcgccaatga atgagtttga gacgctgacg gcgaagtttc actttgttga tctggcggga
     1081 tcggaaagac tgaagagaac cggagctaca ggcgagagag caaaagaggg catttccatc
     1141 aactgcgggc ttttggctct tgggaatgta atcagcgcct tgggggacaa gagcaagaga
     1201 gccacccatg tcccttacag agactctaag ctgacaagac tcttgcagga ttcccttggg
     1261 ggtaacagcc aaaccatcat gatagcatgc gtcagccctt cagacaggga tttcatggag
     1321 acgttaaaca ctctgaagta cgccaatcga gcgagaaata tcaagaacaa ggtgatggtc
     1381 aatcaagaca gagccagtca gcaaatcaac gcgctgcgga gcgagatcac gcgccttcag
     1441 atggagctca tggaatacaa aaccggtaaa agaataattg acgaggaagg cgtggaaagc
     1501 atcaatgaca tgtttcatga gaatgctatg ctgcagacgg aaaataataa tctgcgtgta
     1561 agaataaaag ccatgcagga gaccgttgat gcactgaggg ccagaatcac gcagcttgtc
     1621 agtgagcagg ccaaccaagt tcttgcccga gcaggtgaag ggaacgaaga gatcagtaat
     1681 atgattcata gttatatcaa agaaattgaa gacctcaggg caaaattatt agaaagtgaa
     1741 gcagtgaacg agaaccttcg gaagaacttg accagagcca cggcgagatc tccttacttc
     1801 agtgcctcct cagctttctc gcctactata ctgtcttcag acaaggagac tatcgaaatt
     1861 atagatctag caaagaaaga cttggagaag ctaaaacgga aagagaagaa gaagaagaaa
     1921 aggctacaga aacttgagga aagcggtcga gaagaaagaa gtgttgccgg gaaagacgat
     1981 aatgcagaca ctgaccagga gaagaaagaa gaaaagggtg tttcagagaa agaaaacaat
     2041 gagctagacg tggaagagaa tcaagaagtg agtgaccacg aggatgagga agaggaggaa
     2101 gaggacgagg aggaagagga tgacattgaa ggagaagaaa gctctgatga atcagattcc
     2161 gaatctgatg aaaaagctaa ctatcaagcc gacttagcaa atatcacctg cgagattgcg
     2221 attaagcaga agctgatcga cgaactggag aacagccaga aacggctgca gaccctgaaa
     2281 aagcagtacg aggagaagct gatgatgctc caacataaga tccgggacac gcagctggag
     2341 agggaccagg tgctccagaa cctaggctcg gtggagtcat actcggaaga aaaggccaag
     2401 aaagtgaagt gcgaatatga gaagaagctc cacgccatga acaaagagct gcagcgactg
     2461 cagacggccc aaaaggagca cgccaggctc ctcaaaaacc agtctcagta tgaaaagcag
     2521 ctcaagaaac tgcagcaaga cgtcatggaa atgaagaaaa ccaaggttcg tctaatgaag
     2581 cagatgaaag aagagcagga gaaagcccgg ctgacagaat ctcgaaggaa ccgggaaatc
     2641 gctcagctga agaaggatca gcgcaagcga gatcatcaac ttagacttct agaggcccag
     2701 aaaagaaatc aagaagtagt tctgcgacgc aaaacggaag aggttacagc tctccgcagg
     2761 caagtgaggc ccatgtctga taaagtagcg ggaaaagtta ctcggaagct gagctcatcc
     2821 gaaagccccg ctccggacac aggttccagt gcggcttccg gggaagcaga cacatcacgg
     2881 ccaggcaccc agcagaaaat gaggatcccc gtggcaagag tccaggcatt accaacacct
     2941 acaacaaatg gcaccaggaa aaaatatcag aggaaaggat tcactggccg ggtgttcact
     3001 tccaagacag cccgcatgaa gtggcagcta ctggagcgcc gggtgaccga catcatcatg
     3061 cagaaaatga ccatctccaa catggaggcg gacatgaaca gactcctcag gcaacgggaa
     3121 gaactcacaa aaaggcgaga gaaactttct aaaaggagag agaagatagt caaggagagc
     3181 ggagagggag ataaaagtgt ggctaacatc atcgaggaga tggagtccct gacagccaac
     3241 atagattaca tcaatgatag cattgccgac tgtcaagcca acatcatgca gatggaggag
     3301 gcaaaggaag aaggggagac attggatgtc accgctgtca ttaatgcctg tacactgaca
     3361 gaagctcggt acctgctaga tcacttcctg tcaatgggca tcaataaggg tctgcaggct
     3421 gcccagaaag aggctcaaat taaagtcctc gagggtcgac tcaaacagac cgaaatcacc
     3481 agtgcaaccc agaaccaact cttattccat atgctgaagg agaaggcaga gctaaaccca
     3541 gagctggatg ccttgctagg ccacgcactg caagatctag atggcgcccc accagaaaac
     3601 gaggaggaca gcagcgagga agatggccct ttacacagcc cggggtcgga gggaagcacg
     3661 ttatcttcag accttatgaa gctttgtggt gaagtgaaac caaagaacaa ggctcgaagg
     3721 agaaccacca ctcagatgga gttgctgtat gcagatagca gtgaagtagc ctcagacact
     3781 agtgcaggag atgcctcctt gtctggccct ctggcacctg ttgcagaagg gcaggagatt
     3841 ggaatgaaca cagagacaag tggtacttct gctagggaca aagagcttct tgccccatct
     3901 ggcttacctt ctaagatagg cagcatttcc agacagtcat ctctatcaga aaaaaaagtg
     3961 ccagagcctt cccctgtaac aaggagaaag gcatatgaga aggcagataa accaaaggcg
     4021 aaggaacata aacactcaga ttcgggcgct tccgagacta gtctctcacc tccttcctcc
     4081 ccaccaagcc ggccccgtaa cgaactgaat gtgtttaatc gccttactgt gcctcaggga
     4141 accccgtcag ttcagcagga taagtctgat gaaagtgact cctctttgtc cgaggtgcac
     4201 agaggcataa tcaacccatt tcctgcctgc aaaggagtca gagcctctcc tcttcagtgc
     4261 gttcacatag ctgaagggca caccaaggct gtgctctgtg tggattctac ggatgatctt
     4321 ctcttcaccg gatcaaaaga tcgcacttgt aaagtatgga atctcgtgac tggacaggaa
     4381 attatgtccc tgggggttca ccctaacaac gtggtgtctg taaaatactg taattatacc
     4441 agtctggtct tcaccgtgtc gacatcttat attaaggtgt gggatatcag agagtcagca
     4501 aaatgcattc gaacattaac atcttcaggt caagttaccc ttggagaagc gtgttctgcc
     4561 agcaccagcc ggacagtagc tattccttcc ggggagagcc agatcaatca aattgcacta
     4621 aacccaactg gcactttcct ctacgcggcc tctggaaatg ccgtcagaat gtgggacctt
     4681 aaaaggtttc agtctacagg aaagctaacc ggacacctgg gtcctgttat gtgccttacg
     4741 gtagaccaga tctccaatgg acaggacctc atcatcactg gctcaaaaga ccactacatc
     4801 aaaatgttcg atgtgactga aggggctctt ggaactgtaa gtcccaccca caacttcgag
     4861 cctcctcatt atgatgggat agaagcactg gccattcaag gcgataacct attcagtggg
     4921 tccagagata atggaatcaa gaaatgggac ttagctcaga aaggtcttct tcagcaagtc
     4981 ccaaatgcac acaaagactg ggtgtgtgcc ctgggcctgg tgccaggcca tccggttttg
     5041 ctgagtggct gcagaggcgg cattctgaaa ctctggaatg tggacacttt tgtgcccgtt
     5101 ggagagatga gaggtcatga cagtcccatc aatgccattt gtgttaactc cacccatgtc
     5161 tttactgctg ctgatgatcg aaccgtgaga atctggaagg cccacaactt gcaagatggt
     5221 caactctctg acaccggcga tctgggggag gatattgcca gtaattaaca tggctgggca
     5281 gaagcagaag ccgacactgt gacgacgctc cgtgttcttt attaaaaacg atgtcccgca
     5341 cttattacta gtggaatcaa ctggaaacat atctcaatcc atggctagat aatgtgtatc
     5401 ctaataaaat tgttctgctt gtatatgaaa tattaatatc taccaacaca tagacttcct
     5461 aaaatcgata tattgcttga atcacacttt tactgtggct gaattttttg tgcctagtta
     5521 taaaaaagac acttcgaatt atttgagtta taaatagctt ttgtgacagg agcataccca
     5581 gaataaaaca cgcctacctg ttaactcgtt caaataatgt ggtcataact tacacattta
     5641 agcgtatatt ggaattgtta actcaaattg tagtcaaaaa aaaaaaatca ggaattttgt
     5701 ccgtgtataa ggggttctaa gtttcaaagc ttgttcagtg tgatggaata acaagatgaa
     5761 ttattggtga tttttcataa tcgatgtggt ctactaagaa agataacaat ttgtgctaaa
     5821 atgcccatgt ttacctgtat tgaccaaagc tttcagttgt tcttcattct gtgctcagga
     5881 ttgaaatgct gcgtagacgt tgtgttgtta gtgctgggca cggattctgg gacggtgagc
     5941 tgttgatttc ctaacagaaa gatattttga tctattttcc tatggaattg tttctattat
     6001 tatcttttaa tttctttttt tatttaatag taatagctcc tttctccttc ctctgatttt
     6061 tatatgctgc taaatatatt ttaaatatac tgtgtttgca cacactggta gctatgtgtt
     6121 tgcacacatt ggtagactgt tatcatttgt ggtgggaacc catgtaaata agtagactgt
     6181 aaagagagac tatcttgcat tatgactgta tgaatttcta agtgctgttt gattgggttt
     6241 tgttacagga tgtataattt atctgtctac tcagaatatt aatttgtaaa ttctgcaagg
     6301 ttaattttat gtaatggtat aacttttgaa attattgtct tatgttattt gttttttttt
     6361 tttttttgcc ctgaaaatat ttgtttgtaa atgaaagttt agctagtgct taaataaaca
     6421 tgtgctatga attgtttcta tta
//
