LOCUS       NM_009004               3473 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus kinesin family member 20A (Kif20a), transcript variant
            3, mRNA.
ACCESSION   NM_009004
VERSION     NM_009004.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3473)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3473)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3473)
  AUTHORS   Qiu,R., Wu,J., Gudenas,B., Northcott,P.A., Wechsler-Reya,R.J. and
            Lu,Q.
  TITLE     Depletion of kinesin motor KIF20A to target cell fate control
            suppresses medulloblastoma tumour growth
  JOURNAL   Commun Biol 4 (1), 552 (2021)
   PUBMED   33976373
  REMARK    GeneRIF: Depletion of kinesin motor KIF20A to target cell fate
            control suppresses medulloblastoma tumour growth.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3473)
  AUTHORS   Qiu,R., Runxiang,Q., Geng,A., Liu,J., Xu,C.W., Menon,M.B.,
            Gaestel,M. and Lu,Q.
  TITLE     SEPT7 Interacts with KIF20A and Regulates the Proliferative State
            of Neural Progenitor Cells During Cortical Development
  JOURNAL   Cereb Cortex 30 (5), 3030-3043 (2020)
   PUBMED   31813992
  REMARK    GeneRIF: SEPT7 Interacts with KIF20A and Regulates the
            Proliferative State of Neural Progenitor Cells During Cortical
            Development.
REFERENCE   5  (bases 1 to 3473)
  AUTHORS   She,Z.Y., Li,Y.L., Lin,Y., Lu,M.H., Wei,Y.L., Yu,K.W., Zhong,N. and
            Xiao,Y.
  TITLE     Kinesin-6 family motor KIF20A regulates central spindle assembly
            and acrosome biogenesis in mouse spermatogenesis
  JOURNAL   Biochim Biophys Acta Mol Cell Res 1867 (4), 118636 (2020)
   PUBMED   31884069
  REMARK    GeneRIF: KIF20A binds the microtubules to organize the central
            spindle assembly during spermatogenesis.
REFERENCE   6  (bases 1 to 3473)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 3473)
  AUTHORS   Vaid,K.S., Guttman,J.A., Singaraja,R.R. and Vogl,A.W.
  TITLE     A kinesin is present at unique sertoli/spermatid adherens junctions
            in rat and mouse testes
  JOURNAL   Biol Reprod 77 (6), 1037-1048 (2007)
   PUBMED   17855729
REFERENCE   8  (bases 1 to 3473)
  AUTHORS   Schwab,K., Patterson,L.T., Aronow,B.J., Luckas,R., Liang,H.C. and
            Potter,S.S.
  TITLE     A catalogue of gene expression in the developing kidney
  JOURNAL   Kidney Int 64 (5), 1588-1604 (2003)
   PUBMED   14531791
REFERENCE   9  (bases 1 to 3473)
  AUTHORS   Miki,H., Setou,M., Kaneshiro,K. and Hirokawa,N.
  TITLE     All kinesin superfamily protein, KIF, genes in mouse and human
  JOURNAL   Proc Natl Acad Sci U S A 98 (13), 7004-7011 (2001)
   PUBMED   11416179
  REMARK    Review article
REFERENCE   10 (bases 1 to 3473)
  AUTHORS   Echard,A., Jollivet,F., Martinez,O., Lacapere,J.J., Rousselet,A.,
            Janoueix-Lerosey,I. and Goud,B.
  TITLE     Interaction of a Golgi-associated kinesin-like protein with Rab6
  JOURNAL   Science 279 (5350), 580-585 (1998)
   PUBMED   9438855
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY012551.1, AK144844.1 and AK084732.1.
            
            On Oct 22, 2009 this sequence version replaced NM_009004.3.
            
            Transcript Variant: This variant (3) has an alternate 5' UTR exon,
            as compared to variant 1. Variants 1-3 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK084732.1, AK083412.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-83                BY012551.1         5-87
            84-3000             AK144844.1         2-2918
            3001-3473           AK084732.1         2944-3416
FEATURES             Location/Qualifiers
     source          1..3473
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 18.69 cM"
     gene            1..3473
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /note="kinesin family member 20A"
                     /db_xref="GeneID:19348"
                     /db_xref="MGI:MGI:1201682"
     exon            1..125
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            126..309
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     CDS             148..2811
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /note="kinesin-like protein 174; rab6-interacting
                     kinesin-like protein; Rabkinesin-6"
                     /codon_start=1
                     /product="kinesin-like protein KIF20A"
                     /protein_id="NP_033030.1"
                     /db_xref="CCDS:CCDS29131.1"
                     /db_xref="GeneID:19348"
                     /db_xref="MGI:MGI:1201682"
                     /translation="MSHRILSPPAGLLSDEDVVDSPILESTAADLRSVVRKDLLSDCS
                     VISASLEDKQALLEDTSEKVKVYLRIRPFLTSELDRQEDQGCVCIENTETLVLQAPKD
                     SFALKSNERGVGQATHKFTFSQIFGPEVGQVAFFNLTMKEMVKDVLKGQNWLIYTYGV
                     TNSGKTYTIQGTSKDAGILPQSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQ
                     EEMKKLSLLIGGLQEEELSTSVKKRVHTESRIGASNSFDSGVAGLSSTSQFTSSSQLD
                     ETSQLWAQPDTVPVSVPADIRFSVWISFFEIYNELLYDLLEPPSHQHKRQTLRLCEDQ
                     NGNPYVKDLNWIHVRDVEEAWKLLKVGRKNQSFASTHMNQQSSRSHSIFSIRILHLQG
                     EGDIVPKISELSLCDLAGSERCKHQKSGERLKEAGNINTSLHTLGRCIAALRQNQQNR
                     SKQNLIPFRDSKLTRVFQGFFTGRGRSCMIVNVNPCASTYDETLHAAKFSALASQLVH
                     APPVHLGIPSLHSFIKKHSPQVGPGLEKEDKADSDLEDSPEDEADVSVYGKEELLQVV
                     EAMKALLLKERQEKLQLEIQLREEICNEMVEQMQQREQWCSERLDNQKELMEELYEEK
                     LKILKESLTTFYQEQIQERDEKIEELETLLQEAKQQPAAQQSGGLSLLRRSQRLAASA
                     STQQFQEVKAELEQCKTELSSTTAELHKYQQVLKPPPPAKPFTIDVDKKLEEGQKNIR
                     LLRTELQKLGQSLQSAERACCHSTGAGKLRQALTNCDDILIKQNQTLAELQNNMVLVK
                     LDLQKKAACIAEQYHTVLKLQGQASAKKRLGANQENQQPNHQPPGKKPFLRNLLPRTP
                     TCQSSTDSSPYARILRSRHSPLLKSPFGKKY"
     exon            310..399
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            400..519
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            520..658
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            659..846
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            847..976
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1171
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1283
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1352
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            1353..1496
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            1497..1662
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            1663..1827
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            1828..1967
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            1968..2070
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            2071..2266
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            2267..2358
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            2359..2496
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     exon            2497..3473
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2977..2982
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /note="hexamer: AATAAA"
     polyA_site      3001
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /note="major polyA site"
     regulatory      3221..3226
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
                     /note="hexamer: ATTAAA"
     polyA_site      3240
                     /gene="Kif20a"
                     /gene_synonym="Rab6kifl"
ORIGIN      
        1 aaaacattgt atgaggaaca aagctgttcc tcgtgggcgg agttgtgctc tccagccgca
       61 ggagtcttgc tgcgcgggtg ggtagaagct gggatcagag aagcggcgag gcagacagtc
      121 ttcggacata gactgactct gcttgtcatg tctcaccgga tcctttctcc gccagcgggc
      181 ttactctctg atgaggatgt tgtagactct cccatattag aatccacagc tgcagatctg
      241 agatctgttg tccgaaagga cctgttgtca gactgctctg tcatctctgc ctctctggag
      301 gacaagcagg ctctactgga ggacacctca gagaaggtga aagtttacct tcgaattcga
      361 ccattcttga cttcagagtt ggaccgacag gaagatcagg gctgcgtctg cattgagaat
      421 acagaaaccc ttgtgctgca ggcacccaaa gactcctttg ccttgaagag taatgagagg
      481 ggagttggtc aggccactca caaatttacc ttttcccaga tatttgggcc agaagtggga
      541 caggtggcct tcttcaatct gaccatgaag gagatggtga aggatgtgct caaagggcag
      601 aactggctca tctacaccta tggagtcacc aactcgggga aaacgtacac cattcaaggt
      661 actagtaagg atgcggggat cctgccccag tccctggctc tcatctttaa tagtctccag
      721 ggccagcttc atccgacacc tgacctgaag cccttattgt ccaatgaagt aatctggcta
      781 gacagcaagc agattcgaca ggaggaaatg aagaagctgt ccttgctaat tggaggcctc
      841 caagaggagg agctgtccac ctccgtgaag aaacgtgtcc acactgaaag tcggataggt
      901 gccagcaaca gctttgacag tggcgttgct gggctgtctt ccaccagtca gttcaccagc
      961 agcagccagc tagatgaaac aagtcaatta tgggcacaac cagacactgt cccagtaagt
     1021 gttccagcag acattcgctt ctctgtctgg atctccttct ttgagatcta caatgaattg
     1081 ctttatgacc tgttagaacc acctagccat cagcataaga gacagacact tcggctgtgt
     1141 gaggatcaga acggcaatcc ttacgtgaaa gatctcaatt ggattcatgt tcgtgatgtt
     1201 gaggaagcct ggaaactatt gaaagtgggt cgcaagaacc agagctttgc cagcacccac
     1261 atgaaccagc aatccagccg cagtcacagc atcttctcaa tcagaatctt gcaccttcag
     1321 ggagaagggg atatagtgcc caagatcagt gaactgtcac tctgtgacct ggctggctct
     1381 gagcgctgca aacatcaaaa aagtggtgag cggctaaagg aggcagggaa cattaacact
     1441 tctctgcaca ccctgggccg ctgtattgct gccctgcgac agaatcagca gaaccggtca
     1501 aagcagaacc tgattccttt ccgtgacagc aagttgactc gtgtgttcca aggcttcttc
     1561 acaggtcgag gtcgttcctg tatgattgtc aatgtgaatc cctgtgcatc tacatatgac
     1621 gagactcttc atgcagccaa attctcagcc ctagccagcc agcttgtgca cgccccacct
     1681 gtgcatctgg gaatcccatc cctgcattca ttcatcaaga agcacagtcc tcaggttggc
     1741 cctggcttag agaaagagga caaggccgac tcagaccttg aggacagtcc tgaagacgaa
     1801 gctgacgtct ccgtgtatgg caaggaggaa ctactccagg tggtggaagc catgaaagcg
     1861 ctacttttaa aagaacgaca agaaaagctg cagttggaga tacagctccg agaggaaatt
     1921 tgcaacgaaa tggtggaaca gatgcaacag cgggagcagt ggtgcagtga gcgtttggac
     1981 aaccaaaagg aactgatgga ggaactgtac gaggagaaac tgaagatcct gaaggaatca
     2041 ctgacaactt tctaccaaga gcagatccag gagcgggatg aaaaaattga agagctagaa
     2101 actctgttgc aggaagccaa acagcagcca gcggcacaac agtcaggggg gctgtccctc
     2161 ctccggcggt cacagaggct ggcagcgtct gcctccactc agcagttcca ggaagttaaa
     2221 gctgaactag agcaatgcaa aacagagtta agctctacca ctgcagagct gcacaagtat
     2281 cagcaagtgt taaaaccgcc acccccagcc aagcctttca ccattgatgt ggataagaag
     2341 ttagaggagg gccagaagaa tataagactg ctacggacag agctccagaa actaggacag
     2401 tctctgcagt cagcagaaag agcctgttgc cacagcaccg gagcaggaaa acttcgtcaa
     2461 gcattaacca actgtgatga catcttaatc aagcagaacc agaccctggc tgagctgcag
     2521 aataacatgg tgctagtgaa actggacctt cagaaaaagg cagcctgcat tgctgagcag
     2581 tatcacactg tgctaaagct ccaaggccaa gcctctgcca aaaagcggct gggagcaaac
     2641 caggaaaacc agcaaccaaa tcatcaaccc ccaggaaaga aaccattcct gcgaaactta
     2701 cttccccgaa cacctacctg ccaaagctca acagacagca gcccttatgc gcggatcttg
     2761 cgctcacggc actctccttt actcaaatct ccctttggca aaaaatacta aagttgtggg
     2821 gatgaagatg catggttgtt gccctgaggt tggtcagctg cttagctgat aagtctcttt
     2881 taagcttcag catacaccca gaactgtatt cagaattatt gtattataat cacctatgta
     2941 atcttgtttt ttttttcatg cacaaatatt atatggaata aagacattgt ttatgctttt
     3001 atttggattc caaatttaga aaaatataaa aagggggaca gaaaattgat ataaatacca
     3061 tctggcctgt tagacccttg gacaggaaca gcagtgggaa ccagcctaat gcacactagg
     3121 aaatgagtac aattttaaat gatacccaag aggcttgggt agctttgtct ggccaggaag
     3181 ttgctatgtc aaaacaccca cctgcctgtc tccaaatggg attaaagaca tgcaccacca
     3241 catggcaccc agttagtgtt ccttccatta aatggggagt aaaatgttct gagtacaaga
     3301 gaaggaaggc tagctcctaa ccacagaatg atctatagca cctactgcac aagctcattg
     3361 tagcagacat caagtggctc tgaaacctag aaaaacacag tgaattcttc aaccttgtag
     3421 ataaggttga aaaccaaatt ggagacttta aaatccgaag taaaaaagct tcc
//
