LOCUS       NM_001102615            3585 bp    mRNA    linear   ROD 27-JUL-2024
DEFINITION  Mus musculus kinesin family member 19A (Kif19a), mRNA.
ACCESSION   NM_001102615 XM_988580
VERSION     NM_001102615.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3585)
  AUTHORS   Arora,K., Lund,J.R., Naren,N.A., Zingarelli,B. and Naren,A.P.
  TITLE     AC6 regulates the microtubule-depolymerizing kinesin KIF19A to
            control ciliary length in mammals
  JOURNAL   J Biol Chem 295 (42), 14250-14259 (2020)
   PUBMED   32683324
  REMARK    GeneRIF: AC6 regulates the microtubule-depolymerizing kinesin
            KIF19A to control ciliary length in mammals.
REFERENCE   2  (bases 1 to 3585)
  AUTHORS   Hou,L., Zhang,Y., Yu,B., Yang,Y., Li,B. and Wu,J.
  TITLE     Oocyte-G1 promotes male germ cell apoptosis through activation of
            Caspase-3
  JOURNAL   Gene 670, 22-30 (2018)
   PUBMED   29802994
  REMARK    GeneRIF: Result showed that overexpression of Oocyte-G1 increased
            apoptosis in cultured cells. Oocyte-G1 transgenic mice also showed
            an increased apoptotic rate in male germ cells. Co-localization
            experiments revealed an interaction between Oocyte-G1 and Caspase-3
            and suggest that Oocyte-G1 may promote male germ cell apoptosis
            through activating Caspase-3.
REFERENCE   3  (bases 1 to 3585)
  AUTHORS   Anderson,A.E., Taniguchi,K., Hao,Y., Melhuish,T.A., Shah,A.,
            Turner,S.D., Sutherland,A.E. and Wotton,D.
  TITLE     Tgif1 and Tgif2 Repress Expression of the RabGAP Evi5l
  JOURNAL   Mol Cell Biol 37 (5), e00527-16 (2017)
   PUBMED   27956704
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3585)
  AUTHORS   Wang,D., Nitta,R., Morikawa,M., Yajima,H., Inoue,S., Shigematsu,H.,
            Kikkawa,M. and Hirokawa,N.
  TITLE     Motility and microtubule depolymerization mechanisms of the
            Kinesin-8 motor, KIF19A
  JOURNAL   Elife 5, e18101 (2016)
   PUBMED   27690357
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3585)
  AUTHORS   Niwa,S., Nakajima,K., Miki,H., Minato,Y., Wang,D. and Hirokawa,N.
  TITLE     KIF19A is a microtubule-depolymerizing kinesin for ciliary length
            control
  JOURNAL   Dev Cell 23 (6), 1167-1175 (2012)
   PUBMED   23168168
  REMARK    GeneRIF: findings suggest that KIF19A, a member of the kinesin
            superfamily, regulates ciliary length by depolymerizing
            microtubules at the tips of cilia
REFERENCE   6  (bases 1 to 3585)
  AUTHORS   Zhang,Y. and Wu,J.
  TITLE     Molecular cloning and characterization of a new gene, Oocyte-G1
  JOURNAL   J Cell Physiol 218 (1), 75-83 (2009)
   PUBMED   18727094
  REMARK    GeneRIF: an open reading frame of 2,994 bp for a new gene
            (Oocyte-G1), which encodes a 997-residue protein, was cloned from
            an ovarian cDNA library (Oocyte-G1)
REFERENCE   7  (bases 1 to 3585)
  AUTHORS   Miki,H., Setou,M., Kaneshiro,K. and Hirokawa,N.
  TITLE     All kinesin superfamily protein, KIF, genes in mouse and human
  JOURNAL   Proc Natl Acad Sci U S A 98 (13), 7004-7011 (2001)
   PUBMED   11416179
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL663079.9.
            
            On Dec 21, 2022 this sequence version replaced NM_001102615.1.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC151053.1, EF570784.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-152               AL663079.9         84568-84719
            153-233             AL663079.9         86323-86403
            234-344             AL663079.9         97521-97631
            345-432             AL663079.9         98379-98466
            433-569             AL663079.9         98752-98888
            570-695             AL663079.9         99920-100045
            696-890             AL663079.9         100338-100532
            891-1037            AL663079.9         100971-101117
            1038-1160           AL663079.9         102146-102268
            1161-1326           AL663079.9         103918-104083
            1327-1501           AL663079.9         104602-104776
            1502-1697           AL663079.9         104902-105097
            1698-1968           AL663079.9         105543-105813
            1969-2090           AL663079.9         105899-106020
            2091-2224           AL663079.9         106667-106800
            2225-2330           AL663079.9         106995-107100
            2331-2418           AL663079.9         107241-107328
            2419-2816           AL663079.9         108311-108708
            2817-2976           AL663079.9         108926-109085
            2977-3585           AL663079.9         109298-109906
FEATURES             Location/Qualifiers
     source          1..3585
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 80.44 cM"
     gene            1..3585
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /note="kinesin family member 19A"
                     /db_xref="GeneID:286942"
                     /db_xref="MGI:MGI:2447024"
     exon            1..152
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            153..233
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            234..344
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            345..432
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            433..569
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            570..695
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            696..890
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            891..1037
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..1160
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..1326
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1501
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            1502..1697
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            1698..1968
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            1969..2090
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            2091..2224
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            2225..2330
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            2331..2418
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            2419..2816
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            2817..2976
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     exon            2977..3585
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3562..3567
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /note="hexamer: AATAAA"
     polyA_site      3585
                     /gene="Kif19a"
                     /gene_synonym="Kif19"
                     /note="major polyA site"
ORIGIN      
        1 gggttgtcag gcagcagcgg aggcggaaga gcgatccgag gaggtgacca tagtggaggt
       61 gcgtctcagc catgccagct gtcgcggcct gaggctcttt acctaccgca atcatgaagg
      121 acagcggtga ctcaaaggac cagcaactca tggtggcact tagggtccgg cccatcagcg
      181 tggctgagct ggaggaggga gctaccctca tcgctcacaa gatggacgag cagatggtgg
      241 ttctcatgga cccaatggag gaccctgacg acattctgcg ggcacaccgg tcccgggaga
      301 agtcatacct ctttgacgtg gcctttgact tcactgccac ccaggagatg gtatatcagg
      361 ccaccaccaa gagcctcatc gagggcgtca tctcagggta caatgccact gtgtttgcct
      421 atggccctac aggctgtggg aagacctaca ccatgctggg cactgaccac gagccaggca
      481 tctatgttcg gaccctcaat gacctgttcc gagccatcga ggagaccagc aatgacatgg
      541 aatatgaggt gtccatgtcc tacctggaga tctacaatga gatgatccgg gacctactga
      601 acccggccct ggggtacctg gagctgaggg aagactccaa aggggtgatc caggtggccg
      661 ggatcaccga agtgtctacc atcaatgcga aggagatcat gcagctgctg atgaagggga
      721 accggcagag gacgcaagag cccacagctg ccaaccagac atcctcccgc tcccacgccg
      781 tgctccaggt ggccgtgcgt cagcgcagcc gggtcaagaa catcctccag gaggtgcggc
      841 agggccgcct gtttatgatt gacctagctg gctccgagcg tgcctctcag acacagaacc
      901 gggggcagcg catgaaggaa ggagcccaca tcaaccgctc tctgctggcc ctgggcaact
      961 gcatcaatgc gctgagtgac aagggcagta ataaatacat caactatcgg gacagcaaac
     1021 tcacccggct cctgaaggat tcactaggcg ggaacagccg cactgtgatg attgcccaca
     1081 tcagtccagc gagcactgcc tttgaagagt cccggaacac cctgacctac gccggccgag
     1141 ccaagaatat taggactcgg gtgaagcaga acctgctcaa cgtctcctac cacatcgctc
     1201 agtacaccag catcatcgct gatctgagag gcgagatcca gagactcaag tgcaagatcg
     1261 accagcaggc tgggcggggt caggcccggg gcaaactgga caggggtgac atccgccaca
     1321 tccaagctga ggttcagcta cacagcgggc aggaagggcc cgcggagatg ggacagcttc
     1381 gggagcaact catcagcgcc ttccacgagc agatggatgt gcgccggcgc ctgctggagc
     1441 tggagaacca ggccatggaa gtccagattg acacctcccg tcacctcctc accatcgccg
     1501 gctgggagca cgagaagtca cgaagggctc tcaagtggcg ggaggagcga aggaaggagt
     1561 cctacaccaa agaggacagt gagaaggact cggacacagg cgatgagcca gataacctgg
     1621 agccacctga agtggcatca gcccgtgaaa acatcgctgc cctggtgggc gaacagaaga
     1681 agttgcgcaa agagaagctg gcgctggagc agcgctgccg agagctgcgt gcgcgtggcc
     1741 ggcgcctgga agagacgctg ccgcgccgca tcggctcgga ggagcagcgc gaggtgctca
     1801 gcctgctgtg ccgcgtgcac gagctggagg tggaaaacac cgagatgcag tcgcacgctc
     1861 tgctccgcga cagcgctctg cgccaccgcc gcgaggctgt gcgccgcctg gagcagcacc
     1921 gcagcctctg cgatgagatc atccagggcc agcggcagat catcgacgac tacaatctgg
     1981 aggttccccg gcacctggag gaactctacg aagtctacct tcgggaactg gaagagggca
     2041 gcctggagcg ggccaccatc atggaccgag tggcctccag agccctgcag gacagctcct
     2101 tgcccaaaat cactccagca ggggccacac tgaccccaga ctctgacctg gagagtgtga
     2161 agacgctaag ttctgaggcc cagcgccccc aaaacaacac cctaccccca cttggcacag
     2221 acagtgagtc ctaccatgtg ttcaaggcca gtcccagggc ctggcaggtg aagagctcct
     2281 ctgtgcctac tccgcccccc atccaggtgg gcagcctggt gacccaggag gccccaccac
     2341 aggacagcct gggcagccag atcaactctt ccccggagag cagcgagaac ctgtcagaga
     2401 tccttctgtc ccataaagag aggaaagaga tcctgacgcg gaccaagtgt atctcggtga
     2461 aggccgccca gcggcgctcc cgggccctgg gaacggaagg gcgccacctg ctggcacctg
     2521 ccacagagcg cagcagccta tccctgcact cgttgagcga ggctgatgat gctcgcccac
     2581 ccgggcaact ggcctgcaag cggccgccca gcccgacact gcagcatgcc atcagcgagg
     2641 acaatctatc tagcagcaca ggcgagggcc cctccagggc ggtaggacct cgaggtgatg
     2701 gcactgggtc ctgggtgcgt ggccagaaga aatgcctcag caaaaaaagg gaggagtcac
     2761 tggaagcgaa gaggaggaag cggaggtctc ggtcctttga ggtcacagga caagggctgt
     2821 cccgtcccaa gacacaccta ctgggacctc gtccctccga gggcctttca gatcgccgga
     2881 tgccggcgtg tgggcggcca tctcctggtg tcaggcatct gggaaaagtc tctctgcctc
     2941 tggccaaggt caaatttcct ccaaaccaga acacaggatc tggaaaccct tcaccccttc
     3001 ttgttgcccc caaccaagcc ggtgtttccc gtagagctac acgtgggccc agcctacccc
     3061 atggctcaag cacctttggc aaagatggac gcctccagca taactgaggg acccaggcac
     3121 ctattattct gaaccccaag actgaacggg gtgtagcagg gactaggagg tggaagctgg
     3181 gcagatgggg atcccataga gcaagagttt agcggactgg gctcccatga cccggaaacg
     3241 gtagagttat ctgcagaact ctgccgtgtt caccctgcca ctagagaggg aggtgagtcc
     3301 cagaggcccg gcttcccagc ctgggacaga gcattattgc caaaaacttg tacagacctg
     3361 gggccagtct cggcttcggc aatgggggag aggagctgtt ggtgagaggg atccctgggc
     3421 ccacccctgg gcctggctga aggtggggga tgggggagga gcccacagga cttcaagtag
     3481 ggaggggagg ggtggggagg gaatctggtt ttgtaacttc tctgttgctt tttttttttt
     3541 tttctttttg cctttctttc aaataaagtc ctactggggt tttga
//
