LOCUS       NM_197959               3345 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus kinesin family member 18B (Kif18b), mRNA.
ACCESSION   NM_197959
VERSION     NM_197959.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3345)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3345)
  AUTHORS   Moreci,R.S. and Lechler,T.
  TITLE     KIF18B is a cell type-specific regulator of spindle orientation in
            the epidermis
  JOURNAL   Mol Biol Cell 32 (21), ar29 (2021)
   PUBMED   34432485
  REMARK    GeneRIF: KIF18B is a cell type-specific regulator of spindle
            orientation in the epidermis.
REFERENCE   3  (bases 1 to 3345)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3345)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   5  (bases 1 to 3345)
  AUTHORS   Hackney,J.A., Charbord,P., Brunk,B.P., Stoeckert,C.J.,
            Lemischka,I.R. and Moore,K.A.
  TITLE     A molecular profile of a hematopoietic stem cell niche
  JOURNAL   Proc Natl Acad Sci U S A 99 (20), 13061-13066 (2002)
   PUBMED   12226475
REFERENCE   6  (bases 1 to 3345)
  AUTHORS   Miki,H., Setou,M., Kaneshiro,K. and Hirokawa,N.
  TITLE     All kinesin superfamily protein, KIF, genes in mouse and human
  JOURNAL   Proc Natl Acad Sci U S A 98 (13), 7004-7011 (2001)
   PUBMED   11416179
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY312717.1, BC057614.1, BQ571943.1 and BQ833635.1.
            
            On Jul 31, 2009 this sequence version replaced NM_197959.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057614.1, AK156592.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-32                BY312717.1         2-33
            33-781              BC057614.1         1-749
            782-782             BQ571943.1         745-745
            783-3326            BC057614.1         751-3294
            3327-3345           BQ833635.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..3345
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 66.48 cM"
     gene            1..3345
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /note="kinesin family member 18B"
                     /db_xref="GeneID:70218"
                     /db_xref="MGI:MGI:2446979"
     exon            1..142
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            143..469
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            470..627
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            628..732
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            733..843
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            844..1041
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1218
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1293
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1394
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1395..1563
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1564..1679
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1680..1885
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1886..2411
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2412..2492
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2493..2578
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2579..3337
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3290..3295
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3326
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
                     /note="major polyA site"
     polyA_site      3337
                     /gene="Kif18b"
                     /gene_synonym="3000004C01Rik"
ORIGIN      
        1 tagtttgaac gcgccgcgcc ggaagaaggt tggttcggtg gaatcgggtg tgggggagct
       61 ctctcctgaa tccgagggct cctgtccgag gcggagggac gcgtaagcga cccccgacac
      121 cagcaccggg aaccgacgag aggtgttgcc atggtgatgg ctgtggaaga cagcgtggtt
      181 cgggtggtcg tgcgggtgag gcctcccacc cctaaggagc tagagagtca gcggcggcct
      241 gtgattcagg tggtagacga gcggatgctg gtatttgacc ccgaggagtg tgatggggga
      301 tttcctggcc taaaatggag tggttcccac aatggcccca agaagaaggg caaagacctg
      361 acatttgtct ttgaccgtgt ctttggtgag atggccactc aggaggatgt gttccagcac
      421 accacacaca acatcctcga cagctttctc cagggctaca actgctcagt gtttgcctat
      481 ggcgccaccg gggctgggaa gacacacact atgctgggga gggagggaga gcccggcatc
      541 atgtacctga ccaccatgga actgtacagg cgtctggaag cccgccagga agaaaagcaa
      601 ttcgaggtgc tcatcagtta cctggaggtg tacaatgagc agatccatga cctcctggag
      661 cccaaaggac ccctcaccat ccgtgaggac ccagataagg gtgttgtggt gccgggactt
      721 tctttccacc agccagcctc agccgagcag ttacttgaga tgctgacaag aggcaactgt
      781 agccgcacac agcaccccac ggatgccaac gccacatcct cccgctctca tgccattttc
      841 cagatctttg tgaagcagca ggaccgggtt ccaggactga cccaggccct tcgagtagcc
      901 aagatgagct tgattgacct ggctggctcc gagcgggcat ccagcaccca tgccaaagga
      961 gagcggctgc gggagggtgc caacatcaac cgctctctgt tagcactcat taatgtcctc
     1021 aatgccctgg ctgatgcaaa gggccgcaag tctcacgtac cctaccgaga cagcaagctg
     1081 acccgcctgc tcaaggactc catcgggggc aactgccgca cagtgatgat tgctgccatc
     1141 agcccttcca gcctgaccta cgaggatact tacaacaccc tcaaatatgc tgaccgtgcc
     1201 aaggagatca gactcacgct gaagagcaat gtgatcagcg tggaccatca cattagccaa
     1261 tatgccacca tctgccagca gctccaggct gaggtagcct tcctgaggga gaaactccag
     1321 atgtatgagg ctggagccca ggccctgcaa cagcagtgct ctccacagcc tcccacgttg
     1381 agcattccac aaagcctttc tagctcctcg ttacagcctg ggccctccag ccagtcctct
     1441 accctagagt gccatgcaaa gaatgaaact cttcaagagg agagcctggg atcagacgcc
     1501 cagggacagg agattgtgga agaaagtgct tcagagcagg agcagtgtcc ccaggacaaa
     1561 cagtgtccaa cccagaagcc agagccgaac ctgcccgggt cccctagtcc aagtgtacag
     1621 gcaaagccag gcacgggcca acactcacca cagaaacagg atgcggacca ctccaaacag
     1681 ttggccctcc aggtgctccg cctggcccag cgacaatact ccctgctgca ggcagccaac
     1741 ctcctgactc ctgacatgat ctcagagttt gagaccctgc agcaactagt gctcgaggaa
     1801 agcgttgacc acagggctga gagccccagg tctcctgctc tggccagagg ggacccacta
     1861 gctcaggcgc tgtgttccga gtctaagtct tcagggtact gtggtccagt gaccaggacc
     1921 atggcaaagc aactgaatgg tctcacacac actctggggg ccccactcgc acctgactgc
     1981 acctcagata agacattcca aaagcctacc aaggagaaga aaaggaagct gacccccgaa
     2041 gagccaggca gcctaccagc cccgaatctg gagatgaagc gccagcgcca gtccttcctc
     2101 ccctgcctaa gaaggggctc tctacctaag gcccagccgt gctctgagcc gagaactccc
     2161 aaaagagaga gggcctcttc cccctctccc tcctcccgag tctgcccagc cacggtcatt
     2221 aaaagccggg tacccctggg cccttctgcc ttacagaact gttccactcc tctggcccta
     2281 cccactcggg acctcaacac caccttcaat gtctctgagg agtccccctc caaacccagc
     2341 ttccaggaat ttgttgactg ggaaaaagtt tccccggagc tgaacagtac cgaccagccc
     2401 tttctcccca gcgcacctgt cttcatattc acgaagggcc gcaagccttc gcttcctgca
     2461 gtcactgcca gcaagaagag gcgtactatg aggccctcag tctcccgagg ccgcagctgt
     2521 attgcccgtc tccacagtag caccttgaag aagccaaaca gacccttcac tgtcccagag
     2581 ccacccttga gcccccactg ccttgatgac cagaggactc ctaaaggact gactggggtg
     2641 acagagtcct attaactggg tgttctgacc acgagggact cctggcatcc acgattgttc
     2701 tgattcgcca atagccttct cttgtctaca gctgccaatg ccaagagtcc ctagcctgcc
     2761 ttcctcacct tggagcaatt aacaccacca tgccttagct ctgttaacac ccctccccaa
     2821 ccacttgtct atttgccttc tttattagtc tctttcacac tcagcttctt ggtatataca
     2881 tattcctttg tgagtgttaa acgtgtggct gtattaaagg atcctgtcag ggtttctcat
     2941 tcccaaagcc ttccacagaa gcaggggact cttgggctct gtcctttacc cctcagcttc
     3001 atgtctgaca acagggctct gcacagtgaa ggtggatgag gacaagaggg ttgctgacaa
     3061 atgccggctt agctctcctg gtgctaaaca cagcatacat tcagaatgta aggagagagg
     3121 ggactgtgag gatagagcct taggtctaaa tgctagctgg ttgtgtcggt agttaggcat
     3181 ccttctcatc tttggcttct ccacattcac atgtattgta tttatatgta tacacatagg
     3241 tgtatgccta tatatatata tatatatata tatatatttt ggctgtaata ataaacatct
     3301 ctgtctttgg tgtcttcttc cttctacact ctggaaaaaa aaaaa
//
