LOCUS       NM_001287179            8338 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus kinesin family member 14 (Kif14), mRNA.
ACCESSION   NM_001287179
VERSION     NM_001287179.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8338)
  AUTHORS   Benoit,M.P.M.H., Asenjo,A.B., Paydar,M., Dhakal,S., Kwok,B.H. and
            Sosa,H.
  TITLE     Structural basis of mechano-chemical coupling by the mitotic
            kinesin KIF14
  JOURNAL   Nat Commun 12 (1), 3637 (2021)
   PUBMED   34131133
  REMARK    GeneRIF: Structural basis of mechano-chemical coupling by the
            mitotic kinesin KIF14.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8338)
  AUTHORS   Sishtla,K., Pitt,N., Shadmand,M., O'Hare,M.N., Sulaiman,R.S.,
            Sinn,A.L., Condon,K., Pollok,K.E., Sandusky,G.E. and Corson,T.W.
  TITLE     Observations on spontaneous tumor formation in mice overexpressing
            mitotic kinesin Kif14
  JOURNAL   Sci Rep 8 (1), 16152 (2018)
   PUBMED   30385851
  REMARK    GeneRIF: this work reveals a novel association of Kif14
            overexpression with lymphoma but suggests that Kif14 does not have
            as prominent a role in initiating cancer in other cell types as it
            does in accelerating tumour development in response to other
            oncogenic insults.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8338)
  AUTHORS   Zhou,L., Dai,H., Wu,J., Zhou,M., Yuan,H., Du,J., Yang,L., Wu,X.,
            Xu,H., Hua,Y., Xu,J., Zheng,L. and Shen,B.
  TITLE     Role of FEN1 S187 phosphorylation in counteracting oxygen-induced
            stress and regulating postnatal heart development
  JOURNAL   FASEB J 31 (1), 132-147 (2017)
   PUBMED   27694478
REFERENCE   4  (bases 1 to 8338)
  AUTHORS   O'Hare,M., Shadmand,M., Sulaiman,R.S., Sishtla,K., Sakisaka,T. and
            Corson,T.W.
  TITLE     Kif14 overexpression accelerates murine retinoblastoma development
  JOURNAL   Int J Cancer 139 (8), 1752-1758 (2016)
   PUBMED   27270502
  REMARK    GeneRIF: Data provide the first evidence that Kif14 can promote
            tumor formation in susceptible cells in vivo
REFERENCE   5  (bases 1 to 8338)
  AUTHORS   Schultz,N.G., Ingels,J., Hillhouse,A., Wardwell,K., Chang,P.L.,
            Cheverud,J.M., Lutz,C., Lu,L., Williams,R.W. and Dean,M.D.
  TITLE     The Genetic Basis of Baculum Size and Shape Variation in Mice
  JOURNAL   G3 (Bethesda) 6 (5), 1141-1151 (2016)
   PUBMED   26935419
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 8338)
  AUTHORS   Ahmed,S.M., Theriault,B.L., Uppalapati,M., Chiu,C.W., Gallie,B.L.,
            Sidhu,S.S. and Angers,S.
  TITLE     KIF14 negatively regulates Rap1a-Radil signaling during breast
            cancer progression
  JOURNAL   J Cell Biol 199 (6), 951-967 (2012)
   PUBMED   23209302
REFERENCE   7  (bases 1 to 8338)
  AUTHORS   Pajovic,S., Corson,T.W., Spencer,C., Dimaras,H., Orlic-Milacic,M.,
            Marchong,M.N., To,K.H., Theriault,B., Auspitz,M. and Gallie,B.L.
  TITLE     The TAg-RB murine retinoblastoma cell of origin has
            immunohistochemical features of differentiated Muller glia with
            progenitor properties
  JOURNAL   Invest Ophthalmol Vis Sci 52 (10), 7618-7624 (2011)
   PUBMED   21862643
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 8338)
  AUTHORS   Miki,H., Setou,M., Kaneshiro,K. and Hirokawa,N.
  TITLE     All kinesin superfamily protein, KIF, genes in mouse and human
  JOURNAL   Proc Natl Acad Sci U S A 98 (13), 7004-7011 (2001)
   PUBMED   11416179
  REMARK    Review article
REFERENCE   9  (bases 1 to 8338)
  AUTHORS   Nakagawa,T., Tanaka,Y., Matsuoka,E., Kondo,S., Okada,Y., Noda,Y.,
            Kanai,Y. and Hirokawa,N.
  TITLE     Identification and classification of 16 new kinesin superfamily
            (KIF) proteins in mouse genome
  JOURNAL   Proc Natl Acad Sci U S A 94 (18), 9654-9659 (1997)
   PUBMED   9275178
  REMARK    Erratum:[Proc Natl Acad Sci U S A 1999 Mar 30;96(7):4214]
REFERENCE   10 (bases 1 to 8338)
  AUTHORS   Winter,H., Siry,P., Tobiasch,E. and Schweizer,J.
  TITLE     Sequence and expression of murine type I hair keratins mHa2 and
            mHa3
  JOURNAL   Exp Cell Res 212 (2), 190-200 (1994)
   PUBMED   7514534
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK087451.1, AC122127.31, AB731728.1 and AC126606.16.
            
            On Jun 6, 2014 this sequence version replaced NM_001287179.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158132.1, AB731728.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-32                AK087451.1         30-61
            33-33               AC122127.31        137451-137451
            34-110              AK087451.1         63-139
            111-5135            AB731728.1         1-5025
            5136-8338           AC126606.16        137590-140792       c
FEATURES             Location/Qualifiers
     source          1..8338
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 59.8 cM"
     gene            1..8338
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /note="kinesin family member 14"
                     /db_xref="GeneID:381293"
                     /db_xref="MGI:MGI:1098226"
     exon            1..1327
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     CDS             111..5135
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /note="N-3 kinesin"
                     /codon_start=1
                     /product="kinesin-like protein KIF14"
                     /protein_id="NP_001274108.1"
                     /db_xref="CCDS:CCDS78693.1"
                     /db_xref="GeneID:381293"
                     /db_xref="MGI:MGI:1098226"
                     /translation="MSVHTSHSRHNIGSLEVSSSQKISASSGLVHSSRLELHLKADMS
                     ECENHDPFVNAGSKTIDINSTYVISACKKTRETPVTSDPRRLSLQRRATCGDRESSLL
                     GSELGNRRTADTSLRLQRRHGRADYVGKWETLNPVGGNPGSDSASQASRTEAKGVNND
                     TRVLSSVVSVKDSNDTGLTRCKDPGPPVGASNEKVTVKDTNSRAPVGSQRQTEAMRSG
                     HLVVQLTESKSDTPVSGGRNSHRGNAGKDTAKQVGTFGSSDTRTPVKCVLEHRWTPRH
                     DPPPPKSPALSTPKNNGKDIPKHGSTFRSASSESRTPVKCVPEHRWTPRHDLPPPKSP
                     ALSTLKNRIASPRVKPRPKSSLFANKRESSRESTLPPEENSLVQKTFTEPDSLKVENS
                     QVTVAVRVRPFSKREKTEKASQVVFTNGEEITVEHPDMKQVYSFIYDVSFWSFDECHP
                     GYASQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSGKSYTMMGLNEEPGIIPRFCED
                     LFAQIAKKQTSEVSYHLEMSFFEVYNEKIHDLLVCKGENGQRKQPLRAREHPVSGPYV
                     EGLSMNVVSSYSDIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEVVEGE
                     EHDHRITSRINLVDLAGSERCSTAHSSGQRLKEGVSINKSLLTLGKVISALSEQANGK
                     RVFIPYRESTLTWLLKESLGGNSKTAMIATVSPAASNIEETLSTLRYATQARLIVNIA
                     KVNEDMNAKLIRELKAEIEKLKAAQRSNRNIDPERYRLCRQEITSLRMKLHQQERDMA
                     EIQRVWKEKFEQAEKRKLQETKELQKAGVTFQMDNHLPNLVNLNEDPQLSEMLLYMVK
                     EGVTTVGKHTPSSSHDIQLSGVLIADDHCTIRNFGGTVSIVPAGEAKTYVNGTHISEP
                     TVLHHGDRVVLGGDHYFRFNHPVEVQKGKKLSSRNNLTTSEGPKDFEFAKNELLTAQR
                     SRLEAEIKDAQLKAKEEMMQGIQIAKEMAQQELSSQKAVYERKIQALEAELREESQRK
                     RLEELNNQKASHKIEELERAKQHLEQEVYVNKRRLEMETLATKQALEDHRIRHARILE
                     ALEIEKQKIAEEVQMLQENRGNRDKTFTIQPNWNSMKLSTMIQEANAISDKFKKCYIF
                     GRHDASDKGRSDTSVRVRNLQLGISTFWSLEKFESKLAAMKELYESNGGDRDEDVFCD
                     PADEWEPDITSTPVSSLSRRRSRSLMKNRRVSGCLHDIHPIQSMQSSHSSGLMEKPST
                     IYSNSSESFLPGICKELIGSSIDFLGQSFDEEKTIADSLINNLLRLHNGVIAISKAHE
                     EQDEESQDNLFSDRAAQALTIQVACAFEQLVVLFKHWLGDFLPCTGSARLEDELRQDI
                     KKLGGYLQLFLQGCCSDISSMVKEAQNKVMKIIQQAVQCVGQLAVLKGSKLCVLENSS
                     KVSSTQEFMAALQDGVTSGMKSLLDSGLETAQDLRQDLSRQSAREEVTKQMKASTVEW
                     VGSLENAVAEWRTKSFRTQAQEGSRQQVSKLLSLASEFLKLKSCLQQTVEMIVSALRG
                     CPSDLHCLRSCTETICSLARKLHSDFSAHSASAGSCGNELPRADCEELESLAKSLLLC
                     FECGESPGLSKPWESCSSNSKEEQCKSDRADCGKSGPRRACEPHGDATPAVSSGDCTP
                     NRIQWV"
     exon            1328..1582
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            1583..1670
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            1671..1769
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1822
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            1823..1853
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            1854..1961
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            1962..2078
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            2079..2194
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            2195..2367
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            2368..2515
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            2516..2579
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            2580..2764
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            2765..2867
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            2868..3031
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            3032..3179
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            3180..3332
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            3333..3459
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            3460..3553
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            3554..3683
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            3684..3784
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            3785..3873
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            3874..4098
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            4099..4280
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            4281..4436
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            4437..4556
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            4557..4631
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            4632..4764
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     exon            4765..8338
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7077..7082
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /note="hexamer: AATAAA"
     polyA_site      7096
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /note="major polyA site"
     regulatory      7199..7204
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /note="hexamer: ATTAAA"
     polyA_site      7230
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
     regulatory      8316..8321
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
                     /note="hexamer: ATTAAA"
     polyA_site      8338
                     /gene="Kif14"
                     /gene_synonym="D1Ertd367e; E130203M01"
ORIGIN      
        1 tcggccagat attttgttgg aaactgaaaa gaacaaaatg cccagcaccc cgacaaggat
       61 ctgaagggct tagatccttc acatcctctt aaaaatcgct tgctgccaag atgtcagtac
      121 acacttcgca tagcagacac aacatcggaa gcctggaggt ttcttcttca cagaagattt
      181 cagcatccag tggcctcgtc cacagcagcc ggctggaact gcacttgaag gcagatatgt
      241 cagagtgtga gaatcatgat ccattcgtga atgctggaag taaaaccatc gacataaata
      301 gcacttatgt tatctctgcc tgtaaaaaaa caagagagac tcctgttacc tctgaccccc
      361 ggagactgag cctccagaga agggctactt gtggggacag agagtcgtct ttacttggaa
      421 gtgagttggg aaacagaaga acagcagaca caagtcttag gttacaacgg cggcacggta
      481 gagcggatta tgtgggaaag tgggagacat tgaatcctgt gggaggtaac ccaggaagtg
      541 actctgcctc ccaggcatcg aggacagaag caaagggtgt aaataatgat acccgtgtcc
      601 tgtcgtctgt cgtctccgtg aaagactcca acgacaccgg gttgacgaga tgcaaagacc
      661 caggtcctcc cgttggtgcc tctaatgaaa aggtgacagt taaggacaca aacagtagag
      721 cgcctgtggg ttcccagcgt cagactgaag ctatgagatc aggacactta gtggtgcaac
      781 tgaccgagag caagtctgat accccagtgt caggaggaag aaactcacac cgtgggaatg
      841 ctggcaagga cactgctaaa caagtcggta catttggaag ctcagataca agaaccccag
      901 tgaaatgtgt tttagaacac agatggacac caaggcatga cccgcctcca ccgaaaagcc
      961 cagctttatc cacaccgaaa aacaatggga aggacatccc gaaacatggc agtacattca
     1021 gaagcgcgag ctcagaatcg aggaccccgg taaaatgtgt cccagaacac agatggacac
     1081 caaggcatga cctgcctcca ccgaaaagcc cagctttatc cacactgaaa aacaggattg
     1141 caagccctcg agttaaaccg aggcccaaaa gttctctttt tgcaaataaa agggaaagct
     1201 cacgagaaag cacactccct ccagaagaaa acagtctagt tcagaagacc tttacagagc
     1261 cagactcctt aaaagtagag aacagtcagg tgaccgtggc ggtgcgcgtg aggcctttca
     1321 gcaaaagaga gaagactgag aaagcatccc aggttgtctt caccaatggg gaagagataa
     1381 ctgtggagca tcccgatatg aaacaagttt actcttttat ttacgatgtt tccttttggt
     1441 cttttgatga atgtcaccct ggctatgcca gccagacaac tgtatatgag acactagctg
     1501 caccactcct ggacagagct tttgaaggct ataacacctg tctctttgct tatggccaga
     1561 ctggctctgg aaagtcctat acgatgatgg ggcttaatga agaaccagga ataattccta
     1621 gattctgtga agatctcttt gctcaaatag ccaaaaaaca aacctcagag gtcagctacc
     1681 atcttgaaat gagcttcttt gaagtttata atgaaaaaat tcatgatctt ctggtttgta
     1741 aaggtgaaaa tgggcagagg aaacaaccac tgcgcgcgag ggagcaccct gtttctggac
     1801 cgtatgttga aggcctgtca atgaatgttg tgagttctta ctctgatatt cagagctggc
     1861 tggaactggg aaataaacag agagccacgg cggccaccgg catgaacgat aaaagctccc
     1921 ggtctcattc tgtgttcacc ctggtgatga cacagaccaa gacagaggtg gtggagggag
     1981 aggaacatga ccacaggatc acgagccgca tcaaccttgt ggacctggcc ggcagtgagc
     2041 gctgctccac cgcccactcg agtgggcagc gactgaagga aggtgtgagc attaacaagt
     2101 ccttgctgac tttggggaag gtcatatctg cactctccga gcaagcaaac ggaaagaggg
     2161 tttttattcc atatcgggaa tccactctta catggctatt aaaagaaagc ctgggtggaa
     2221 attcaaaaac agccatgatt gctaccgtca gtcccgctgc cagcaacata gaggaaacgc
     2281 tgagcacact cagatacgcc acccaagccc gcctgatagt caatatcgcc aaagtcaacg
     2341 aggacatgaa tgcaaagttg atcagagagt tgaaagcaga aattgaaaag ttaaaagctg
     2401 cccagagaag caatcggaac attgaccctg aacggtaccg actctgtcgg caagagataa
     2461 cgtccttaag gatgaagctg catcagcagg agagagacat ggcagagatt cagagagtat
     2521 ggaaggaaaa gtttgaacaa gctgaaaaaa gaaaacttca agagacaaag gagttacaga
     2581 aagcaggagt tacatttcaa atggacaacc acttgccaaa ccttgtcaat ctcaatgaag
     2641 acccacagct gtcggagatg ctgctctaca tggtaaagga aggagtgacc acagttggaa
     2701 agcacacacc aagctcaagc catgacatcc agttgtctgg agtgctgatt gccgatgatc
     2761 actgtactat cagaaatttt ggaggaacag tgagtattgt cccagctgga gaagcaaaga
     2821 catatgtaaa cgggacgcac atctcggagc ccacagtgtt acatcatggt gatcgggtgg
     2881 ttcttggtgg agatcattat tttagattta atcatccagt tgaagtccag aaaggaaaaa
     2941 aactgtcaag tagaaataat ctcacaacaa gcgaaggccc aaaagatttt gagtttgcca
     3001 aaaatgagtt acttacagca cagaggtctc ggcttgaggc agaaattaaa gatgcgcagc
     3061 tgaaggcgaa ggaagaaatg atgcaaggaa ttcagatcgc aaaggagatg gcccagcaag
     3121 aactttcttc ccaaaaagct gtgtatgagc gcaaaatcca ggccctagag gcggagctga
     3181 gggaagagtc tcaaaggaag agattggagg aattaaataa ccaaaaagct agtcacaaga
     3241 ttgaggagtt ggaaagggcg aagcagcatc ttgaacagga agtgtacgtg aacaaaaggc
     3301 gactggagat ggagaccctg gccacaaagc aggccttaga agaccataga atccgacatg
     3361 caaggatctt agaagcttta gaaattgaaa agcaaaagat cgctgaagaa gtacaaatgc
     3421 ttcaggagaa tcggggaaac agggataaaa ctttcaccat tcagccaaac tggaactcca
     3481 tgaaactctc cacgatgatt caggaagcca atgccatcag tgacaaattt aaaaagtgct
     3541 atatttttgg cagacatgat gcatcagaca aaggccgttc tgatacctct gttcgagttc
     3601 gtaacctcca gcttgggatc tcaactttct ggagcctgga aaagtttgaa tctaaacttg
     3661 cagcaatgaa agagctttat gagagtaacg gtggtgacag ggatgaggat gtcttctgtg
     3721 accctgcaga tgagtgggag cccgacatta caagcacacc agtttcttcc ctttctagaa
     3781 ggaggagcag aagtttgatg aagaacagga gagtctctgg ctgtctgcat gacatccatc
     3841 cgattcagag catgcagtct tcacactcat ctggattaat ggaaaaaccg agcaccattt
     3901 actcaaattc atcagagtcc tttcttcccg ggatttgcaa agaattgatt ggctcatcaa
     3961 tagatttcct cggacagagt ttcgatgaag agaaaactat agcagatagc ctgataaata
     4021 atctccttag gcttcataat ggggtgattg ccatctccaa agcccatgaa gagcaggatg
     4081 aagaaagtca agataacctg ttctctgacc gggcggcaca ggctcttacc atccaggttg
     4141 cttgtgcctt tgagcagctt gtggttttgt tcaaacactg gctgggtgat tttctacctt
     4201 gtactggctc agcgaggctt gaagacgaat tgagacaaga tattaaaaaa ctcggaggct
     4261 atttgcaatt gtttttgcag ggatgctgtt cggatatttc atcgatggtt aaagaggctc
     4321 aaaacaaagt catgaagatt atacagcagg ctgttcagtg tgtgggtcag ctagctgttc
     4381 tgaaagggag caagctctgt gttctggaaa acagcagcaa agtctccagt acccaggagt
     4441 tcatggccgc tctccaggat ggtgtaacct ctgggatgaa gagtctctta gactctgggc
     4501 tggagaccgc gcaagacctc aggcaggacc tctccaggca gagtgcacga gaggaggtca
     4561 ctaagcagat gaaagccagt actgtggagt gggtcgggtc tctggaaaat gctgtcgctg
     4621 aatggaggac gaaaagcttc agaactcaag cacaagaagg ttctagacaa caagtttcca
     4681 agctgttaag ccttgcgtca gaattcttga agctgaagtc gtgcttgcaa caaaccgttg
     4741 agatgattgt atctgcgctg agagggtgcc ccagtgactt gcactgtctc agaagctgca
     4801 ccgagactat ctgcagcctg gctcgcaagc ttcacagtga cttcagcgca cactctgcct
     4861 ctgctggcag ctgcggaaat gaactgcctc gtgctgactg tgaggaactg gagtctctag
     4921 cgaagtcact cctcctatgt tttgaatgtg gagaaagccc tggtttgtcg aaaccctggg
     4981 agtcttgttc ttcgaatagc aaggaagagc agtgcaagtc agacagggct gactgcggga
     5041 aaagcgggcc aagacgcgcc tgtgaaccac acggagacgc aaccccagca gtgtcctctg
     5101 gggactgcac cccgaatagg attcagtggg tatgaaacca ttgtgcactt ggagaccgtc
     5161 catgaccaaa aaggacactt ggtgtcactt ttcctcgtgc aggagagcat aaaaagagag
     5221 gagtgtaaat attccaagtc catgcctgtg tgtggcctct cgctgggtgt agaaagcgct
     5281 aacagtgcgg agtgctggct tcagaatgcc tctgtgtatg ctcagaattc tataagcaga
     5341 tgagttttaa acaaagaata ttgtttaaaa atgttgaaat attggcatca gaatgaaatt
     5401 aaggtatcag gaccaagtga gtgactatgg tcctagtttc tcatcttaaa ttttttttct
     5461 ttttttttat tggttatttt atttatttgc atttcaaatg ttatccccct tcccaatttt
     5521 ccctccacaa gcctcctaac ccctcctcct cccccctgct tctatgaggg tgctccccca
     5581 cccacccacc cacccactcc cacttcacca ccctggtgct gtctagctgg ttcattggtc
     5641 tgtttgtaga tagttatttt ctcctgaatg gaaatctaaa cagtttgtta ctttgggcct
     5701 gtgcattctc tcccccaaat atagcatatg gattaagttt atgtgaaatt attagcacag
     5761 gtttaaccaa ggtagctgac taaaactaca gctctttgtc caagaatcaa ctgtttgcca
     5821 tcttcaataa tatatatgtg tgatttgttt cttttcaaaa tgtacataaa aagataatat
     5881 aattgcatat taataatatg accagatagc atcgtagctt actgtgtttt ctgtgttcca
     5941 cagtggttgc ttcatttata aaatttaaaa gtagtagtga aatgtaacca gaaccacttg
     6001 ggaggtcaga ggctgccccc ttttgatagt gcttgttttg ctaaagggta cttagtttac
     6061 atgttgtttg atggagatta aagatccttt ttatatttca tagccttaag aacccttcat
     6121 ctacaatcaa gtctaaagat aatatcctac tttagggttt gacttaagga aattgtttat
     6181 tttttacctc aagaatatgt gtaatttgaa agatatttag tatcttagcc tgggtgacct
     6241 gagcaggttc tgtaagggac ttcccgtgag tggcctgctt ttggctgtag ctgctgcctg
     6301 tacattcagt ggagctcggt gacactggct tgaagatacc tgttgttttc tctatgggga
     6361 gagataggag agcagcactc tctcccgtgg tcggctgagc cgtggtggtc catcccttgt
     6421 gcctccagga gctttgaaga ggtgcagtca ccaggccatt ctgagtgccc cgtcctgtcg
     6481 gatgtgtggc agcagagtga ccaggccatt ctgagtgccc tgtcctgtcc tgtcggacag
     6541 agaggattgg tttccctttc cctctttggc cactgggttt cctcctgcgg ttcactctgt
     6601 accggtcatt gctctggaag taacacttct gttaccgagt tcatacgctg tgaagtacgc
     6661 ggaaggattc ttcctgagcg ctgagcttcc ttgaacttac tcaagtacca aaatggcagt
     6721 tttcaccttg ctgtgcaata atctttagtt tctccatctc ttatccccct tgtttttttt
     6781 ttttccttgc ttttagactt ggtccagctg agcagtgcgg tgtggcctca ccctgtcacc
     6841 ttgctgcctt tgcctcctga atgctggggt tacagtcagt cccccaaacc caagcccaaa
     6901 cccagctagt gtctatcttt caaactcatg tctgtcctca aaaatattgt gggtatgctt
     6961 gtaagcttat ttatatttat gctaaataat ctgtgggact gtgttcgagt gggtggtgca
     7021 gaaggcattg ctgtcagaat catgtgcatg aaaagtgttg taaaggaagt gcctttaata
     7081 aatctcatga gctccagaac cgcctcctaa tccaggacct ttcttattga attattttca
     7141 ttcacttcat cgtgatttaa aaaatgtcac tgtggctctg cctgtctact acatatcaat
     7201 taaataggaa acactagatt catgctaaaa tcattgtggc cactgtgtcg cttttcttgc
     7261 ttgttccctt ctagaggtgg ggaccgaatc caggtgctgt cactaagcta ccacgtagcc
     7321 cctcctttct ccctcctgaa caatgtccca ccctctgggt tggctggaca tggatcagcc
     7381 ttatttccca gttctctgct tggaagctgg gtgtgcgttt tatgcactga acactgtact
     7441 gcaggccggt gagtaactac accaccttaa atgaggcact agctgcttcc ttcctggttc
     7501 ctcatctgca gaaggaaaag tcccaccact tcatggacta tgtccgtggg cactgggtga
     7561 cagagaggaa ggagggcgct tgcccagtag cagatgataa gccaatggta gtctcccttc
     7621 tgtaacgagc agcaaaacct tgttacataa acaacatgcc tttagtctca gcactcagga
     7681 ggcagaggca ggcagatctc tgagctcgag gacagcctgg tctacacaga gaaaccctgt
     7741 ctcaaataag atcatacctg gtgcaagcag atgccaatgt tgtgtattac agcccttgaa
     7801 gcatgatgtg tttaatagta tatctaccaa cactggtttc cacagtaact gatataagga
     7861 tgagtgaatt ccagtgttca cagtccgttc acgtcttttg gtgtctatat tacagttgtc
     7921 caatctgctc agcagtgtac tgtgatggtt agttttaatc gttgggttgg cacatctaga
     7981 gtcacctggg aagggagtct cactgaggga ttgtctgtgt taggctggcc cgtgggcacc
     8041 tctgtgtgat gttggcttga ctgcatttgt cgaagtgcta ttgcctgggc agaggtctct
     8101 gaactgtaga ggatggagaa agtgatagga gaactaccgt gcttgcatta attcattgtt
     8161 ctctgctctt gactgggaat gaacgaatag ctgcttccag gtcctgcagc cttgtcttat
     8221 ccgtgatgat ggactgtacc cttagccaaa taagctgtca ccctgaagtt gcttctgttc
     8281 gggtatttta tcataagaaa aaaaaaaact aggacattaa aatttttcca aaatggca
//
