LOCUS       NM_183322               1950 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus KH domain containing 1A (Khdc1a), mRNA.
ACCESSION   NM_183322 XM_001471897
VERSION     NM_183322.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1950)
  AUTHORS   Cai,C., Tamai,K. and Molyneaux,K.
  TITLE     KHDC1B is a novel CPEB binding partner specifically expressed in
            mouse oocytes and early embryos
  JOURNAL   Mol Biol Cell 21 (18), 3137-3148 (2010)
   PUBMED   20668163
  REMARK    GeneRIF: The paper describes the connection of this gene to
            translational machinery including CPEB
REFERENCE   2  (bases 1 to 1950)
  AUTHORS   Pierre,A., Gautier,M., Callebaut,I., Bontoux,M., Jeanpierre,E.,
            Pontarotti,P. and Monget,P.
  TITLE     Atypical structure and phylogenomic evolution of the new eutherian
            oocyte- and embryo-expressed KHDC1/DPPA5/ECAT1/OOEP gene family
  JOURNAL   Genomics 90 (5), 583-594 (2007)
   PUBMED   17913455
REFERENCE   3  (bases 1 to 1950)
  AUTHORS   Rajpal,A., Cho,Y.A., Yelent,B., Koza-Taylor,P.H., Li,D., Chen,E.,
            Whang,M., Kang,C., Turi,T.G. and Winoto,A.
  TITLE     Transcriptional activation of known and novel apoptotic pathways by
            Nur77 orphan steroid receptor
  JOURNAL   EMBO J 22 (24), 6526-6536 (2003)
   PUBMED   14657025
REFERENCE   4  (bases 1 to 1950)
  AUTHORS   Motoyama,N., Okada,H. and Azuma,T.
  TITLE     Somatic mutation in constant regions of mouse lambda 1 light chains
  JOURNAL   Proc Natl Acad Sci U S A 88 (18), 7933-7937 (1991)
   PUBMED   1910169
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY725559.1, AK136166.1, BB712184.1 and AK162365.1.
            
            On or before Aug 8, 2008 this sequence version replaced
            XM_001471897.1, NM_183322.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY238603.1, AK136166.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-74                BY725559.1         38-111
            75-901              AK136166.1         2-828
            902-952             BB712184.1         324-374
            953-1950            AK162365.1         49-1046
FEATURES             Location/Qualifiers
     source          1..1950
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 6.59 cM"
     gene            1..1950
                     /gene="Khdc1a"
                     /gene_synonym="AU014713; C88118; Ndg1"
                     /note="KH domain containing 1A"
                     /db_xref="GeneID:368204"
                     /db_xref="MGI:MGI:2676610"
     exon            1..443
                     /gene="Khdc1a"
                     /gene_synonym="AU014713; C88118; Ndg1"
                     /inference="alignment:Splign:2.1.0"
     CDS             344..844
                     /gene="Khdc1a"
                     /gene_synonym="AU014713; C88118; Ndg1"
                     /note="Nur77 downstream protein 1; nur77 downstream gene 1
                     protein; KH homology domain containing 1A"
                     /codon_start=1
                     /product="KH homology domain-containing protein 1A"
                     /protein_id="NP_899145.2"
                     /db_xref="CCDS:CCDS14848.1"
                     /db_xref="GeneID:368204"
                     /db_xref="MGI:MGI:2676610"
                     /translation="MSDLRRKGWWNVPDYFHSPLVFDMEEDKEDYIFGPHDEYLHTLE
                     VHSNTLIQLERWFTPTGQTRVTVVGPLKARLWVMDMIRKVGSKNNLDQIKGKMMLLQI
                     RDHPLRDRDLELHPESGSSLWITTMNDTTFVEVPHFLRFPLTVAWLFCGFVRILGIHN
                     FADLHW"
     exon            444..626
                     /gene="Khdc1a"
                     /gene_synonym="AU014713; C88118; Ndg1"
                     /inference="alignment:Splign:2.1.0"
     exon            627..1950
                     /gene="Khdc1a"
                     /gene_synonym="AU014713; C88118; Ndg1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1927..1932
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Khdc1a"
                     /gene_synonym="AU014713; C88118; Ndg1"
                     /note="hexamer: AATAAA"
     polyA_site      1949
                     /gene="Khdc1a"
                     /gene_synonym="AU014713; C88118; Ndg1"
                     /note="major polyA site"
ORIGIN      
        1 gatcttcctc ctccagctct ttcattcctc cccagcctcc agcgacttct ctactccatg
       61 gtctgtagat ctgctccaga aattttgaca ttataaagaa gaaaatttta ggtgtttgga
      121 cattcaagtg aagactaatc agattatcta agagtaatca cagggagttt cgaagggaga
      181 acttagaggc atttgagtct cctccctaag gtgggtcaaa gcttgttcct tgggagtgag
      241 catacatata tagctcctaa agccagaact gcctttctac ggagcaacaa gctgtctgga
      301 attgctttgt tctaaggcaa gtaggatcct tcagaagaca ggaatgagtg acctccgcag
      361 gaagggatgg tggaatgtgc ctgactactt ccacagccca ctggtgtttg acatggaaga
      421 ggacaaggaa gactacatat ttggccctca tgatgaatac cttcacaccc tggaggtcca
      481 cagcaacacc ctcatccagc tggaaagatg gttcacaccc acaggccaaa cccgagtcac
      541 tgtggtgggg ccacttaagg caaggctgtg ggtgatggac atgatcagaa aagtggggag
      601 taagaacaat ttggatcaaa ttaaaggcaa gatgatgcta ctgcagatcc gggatcatcc
      661 tctgagggat cgagacctgg agcttcatcc ggaatcaggg agcagtcttt ggattaccac
      721 aatgaatgat acgacttttg tggaagttcc tcacttcttg aggtttcctt tgacagttgc
      781 ttggttgttt tgtggttttg tgagaattct tggtattcat aacttcgcag acctccattg
      841 gtaaatgctt tgggaaagca gcagtttgga aaagcagtgt tggtggtggt ggtgggtggg
      901 tgggggacag gtgtttcatc ggcctttaaa aattaataaa agatagtcaa ggaactttga
      961 attgtggacc atattggcaa tctctagaat tgtaaggcat aagattacac tcttgctggt
     1021 gtaagattct ggcaaaggta tctgtgacag gcaatgcctt tgatgttggt ctcttttgtc
     1081 tacactaatc cgacctagtg gtagaatttc tgggcaaggc agattccaag gtctgggaag
     1141 gctacaattt ctcccaagaa ttacaatctg ggaggtggga gtggaaacaa gatgtaaatt
     1201 gcttctctca catggaagca ccttaggctg tgttactggg agtgtctgat taaagcaagt
     1261 tgtatttaaa atcgcaggag ggcctggcta gactactgcc agggtgacct gccatagtta
     1321 gtttttaaat caaactggtt catggtagta tttacttggc acacaatttt tttttcaaag
     1381 tcaaaacatt tattatgcac ttaacaaagg gggacaatct tctcatggaa aggtgcccct
     1441 attatgacac gctcaaacta caatagtact agtgaagaaa agaatgcttg acactttttg
     1501 cagatggaac atccattctc ttgctcagag gaagatcttt cctttacaat gtgtctcagg
     1561 cttttaggtg cttgacatat ccatgttcct atcagcaatg gacattgact ttcgattttg
     1621 tccatctcta atactcagct ttcatttttt tgttccacaa tcaatattcc agtagttctc
     1681 tctggtatag gcaatgctgg gtctccagat cataaactta ggacccacaa cagtttaaac
     1741 atttggatgt agcaaatgtg actctgttgg gctgcctatt agcccagatt atgtccagaa
     1801 gacataattt caactaactc ggatttaata ggagttcatt taagtccttt acagagaaag
     1861 ttgtcttcta ggaattcttg ctgatacttg taacttcttg aagattaatc tgttactatt
     1921 tgttctaata aagatacagg tgggtacatg
//
