LOCUS       NM_029550               1678 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus kidney expressed gene 1 (Keg1), mRNA.
ACCESSION   NM_029550
VERSION     NM_029550.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1678)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1678)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 1678)
  AUTHORS   Tang,F., Barbacioru,C., Nordman,E., Bao,S., Lee,C., Wang,X.,
            Tuch,B.B., Heard,E., Lao,K. and Surani,M.A.
  TITLE     Deterministic and stochastic allele specific gene expression in
            single mouse blastomeres
  JOURNAL   PLoS One 6 (6), e21208 (2011)
   PUBMED   21731673
REFERENCE   4  (bases 1 to 1678)
  AUTHORS   Kim,S.C., Sprung,R., Chen,Y., Xu,Y., Ball,H., Pei,J., Cheng,T.,
            Kho,Y., Xiao,H., Xiao,L., Grishin,N.V., White,M., Yang,X.J. and
            Zhao,Y.
  TITLE     Substrate and functional diversity of lysine acetylation revealed
            by a proteomics survey
  JOURNAL   Mol Cell 23 (4), 607-618 (2006)
   PUBMED   16916647
REFERENCE   5  (bases 1 to 1678)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   6  (bases 1 to 1678)
  AUTHORS   Nakadai,T., Okada,N., Makino,Y. and Tamura,T.
  TITLE     Structure of rat gamma-tubulin and its binding to HP33
  JOURNAL   DNA Res 6 (3), 207-209 (1999)
   PUBMED   10470852
REFERENCE   7  (bases 1 to 1678)
  AUTHORS   Nakadai,T., Kishimoto,T., Miyazawa,Y., Okada,N., Makino,Y.,
            Obinata,T. and Tamura,T.
  TITLE     HP33: hepatocellular carcinoma-enriched 33-kDa protein with
            similarity to mitochondrial N-acyltransferase but localized in a
            microtubule-dependent manner at the centrosome
  JOURNAL   J Cell Sci 112 (Pt 9), 1353-1364 (1999)
   PUBMED   10194414
REFERENCE   8  (bases 1 to 1678)
  AUTHORS   Takenaka,M., Imai,E., Kaneko,T., Ito,T., Moriyama,T., Yamauchi,A.,
            Hori,M., Kawamoto,S. and Okubo,K.
  TITLE     Isolation of genes identified in mouse renal proximal tubule by
            comparing different gene expression profiles
  JOURNAL   Kidney Int 53 (3), 562-572 (1998)
   PUBMED   9507200
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC150901.2, AK165515.1 and AI099383.1.
            
            On May 7, 2009 this sequence version replaced NM_029550.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC010803.1, AK002360.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AC150901.2         97763-97765
            4-1663              AK165515.1         2-1661
            1664-1678           AI099383.1         1-15                c
FEATURES             Location/Qualifiers
     source          1..1678
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 8.73 cM"
     gene            1..1678
                     /gene="Keg1"
                     /gene_synonym="0610008P16Rik; GS4059"
                     /note="kidney expressed gene 1"
                     /db_xref="GeneID:64697"
                     /db_xref="MGI:MGI:1928492"
     exon            1..52
                     /gene="Keg1"
                     /gene_synonym="0610008P16Rik; GS4059"
                     /inference="alignment:Splign:2.1.0"
     exon            53..142
                     /gene="Keg1"
                     /gene_synonym="0610008P16Rik; GS4059"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..952
                     /gene="Keg1"
                     /gene_synonym="0610008P16Rik; GS4059"
                     /EC_number="2.3.1.13"
                     /note="Acyl-CoA:glycine N-acyltransferase protein Keg1;
                     kidney-expressed gene 1 protein"
                     /codon_start=1
                     /product="glycine N-acyltransferase-like protein Keg1"
                     /protein_id="NP_083826.1"
                     /db_xref="CCDS:CCDS29636.1"
                     /db_xref="GeneID:64697"
                     /db_xref="MGI:MGI:1928492"
                     /translation="MFCLQSSQALQVLENSLRKHLPESLKVYGTVFHINQGNPFKLKT
                     LVDKWPDFNTVVIRPQEEDMTDDLDHYNNTYLVYSKDPKHCQEFLGSSEVINWKQHLQ
                     IQSSQSDLGKVIESLGATNLGKVKHKQCFLYMVCQTAKKLAPSLMDAKNLVVSRNKLT
                     PLDQQLFKFASLDVTHAALVNSLWHFGGNEKSQKFIERCIFTFPSFCIMGPEGTPVSW
                     TLMDHTGELRMGGTLPKYRRQSLIYHVASQQIQTLEKLGFPMYAHVDKANFTVQRMVG
                     LLGQILLPCTWNQWNCVPL"
     exon            143..250
                     /gene="Keg1"
                     /gene_synonym="0610008P16Rik; GS4059"
                     /inference="alignment:Splign:2.1.0"
     exon            251..377
                     /gene="Keg1"
                     /gene_synonym="0610008P16Rik; GS4059"
                     /inference="alignment:Splign:2.1.0"
     exon            378..549
                     /gene="Keg1"
                     /gene_synonym="0610008P16Rik; GS4059"
                     /inference="alignment:Splign:2.1.0"
     exon            550..1672
                     /gene="Keg1"
                     /gene_synonym="0610008P16Rik; GS4059"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1630
                     /gene="Keg1"
                     /gene_synonym="0610008P16Rik; GS4059"
                     /note="major polyA site"
     regulatory      1637..1642
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Keg1"
                     /gene_synonym="0610008P16Rik; GS4059"
                     /note="hexamer: AATAAA"
     polyA_site      1656
                     /gene="Keg1"
                     /gene_synonym="0610008P16Rik; GS4059"
ORIGIN      
        1 actgcttgtt ctttgttctg aggaagctct ctgtgtggat acggagttat aggtatcaga
       61 agagatgttc tgcttacaga gttcccaagc actgcaggtt ctggagaatt ccctaaggaa
      121 gcacctccct gagtccttaa aggtttatgg gactgtcttc cacatcaatc agggaaaccc
      181 attcaagctc aagactttgg tggacaaatg gcctgatttt aatactgttg ttattcgacc
      241 ccaggaagag gacatgacag atgaccttga ccactacaac aacacttatc tagtgtattc
      301 aaaggatccc aagcactgtc aggaattcct tggctcatca gaagttatta actggaaaca
      361 acatttgcag attcaaagtt cacagtcaga cctgggcaaa gtgatagaaa gtcttggagc
      421 cactaacttg ggcaaggtca agcataagca gtgctttctc tatatggtat gccaaacagc
      481 aaagaaactg gctccttcct tgatggatgc aaagaactta gtagtcagcc gtaacaagct
      541 cacgcctctt gaccagcagt tattcaaatt tgcctcactg gatgttacac atgctgcact
      601 ggtgaatagc ctctggcatt ttggtggcaa tgagaagagc cagaagttca ttgaacgctg
      661 tatctttacc ttccccagct tctgtattat ggggcctgag gggacccctg tgtcctggac
      721 cctgatggac cacactggag aactgagaat gggaggcacc ttgcctaagt accggcgcca
      781 gagtctcatt taccatgttg cttcccagca gattcagaca ctagaaaagc ttggctttcc
      841 catgtatgca catgtggata aggctaactt cactgttcag agaatggttg gcttgctggg
      901 gcaaatcctc ttgccttgta cctggaacca gtggaactgt gtaccgctat aaagctagaa
      961 aagggtgaga aggggcctgc gcttgtagac ggagaaatgg ctgagagaac agagagaagt
     1021 gaactgtcat taggatggtg tgagtttcta gagagcagag gtgcacctcg ctgagcttca
     1081 caccctgttt ccgcgcgctc accttgttca tgctcttaac tccattcttt ggcatgcaga
     1141 aggccacctt ctcctcctcc acccctgtta cagctcccac attctcagga ttcctctaac
     1201 acatttggct aaattgtact cttttctatt tgttttgctg gctcattgat ccatgcccat
     1261 tagtcagtag tttgtgacct atcctgcact ccccttgcac acaaggcata cctcctctga
     1321 ctttctgtag ttttgctttt atgggctgga gaagtagccc gtcatctaaa aagatgtttt
     1381 caaaaatgat tctttctcac gccactcact aggcagtata ttgttaatat gtaaaaacta
     1441 ccatatatgc aaacacagat gcacaatatg tgtggtgcaa ctgtaagaat tattaggaaa
     1501 gagacaagta aatgtgcttg cagccaagcc tggaaacctg aatgtgattc ctgggaccca
     1561 tttgtaaaag gagagcatca actccattac cttgccctct gactgccaca ggtatggagc
     1621 agtatttgca cacacaaata aataaatgta ttatttcaaa agttaaaaaa aaaaaaaa
//
