LOCUS       NM_001403371            6892 bp    mRNA    linear   ROD 07-AUG-2024
DEFINITION  Mus musculus lysine (K)-specific demethylase 6A (Kdm6a), transcript
            variant 3, mRNA.
ACCESSION   NM_001403371 XM_006527595
VERSION     NM_001403371.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6892)
  AUTHORS   Gao,C.W., Lin,W., Riddle,R.C., Chopra,S., Kim,J., Boukas,L.,
            Hansen,K.D., Bjornsson,H.T. and Fahrner,J.A.
  TITLE     Growth deficiency in a mouse model of Kabuki syndrome 2 bears
            mechanistic similarities to Kabuki syndrome 1
  JOURNAL   PLoS Genet 20 (6), e1011310 (2024)
   PUBMED   38857303
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6892)
  AUTHORS   Zhang,D., Zhao,X., Gao,Y., Wang,M., Xiao,M., Zhu,K., Niu,W. and
            Dai,Y.
  TITLE     Inactivation of KDM6A promotes the progression of colorectal cancer
            by enhancing the glycolysis
  JOURNAL   Eur J Med Res 29 (1), 310 (2024)
   PUBMED   38840262
  REMARK    GeneRIF: Inactivation of KDM6A promotes the progression of
            colorectal cancer by enhancing the glycolysis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6892)
  AUTHORS   Cheng,M.I., Hong,L., Bustillos,C., Chen,B., Chin,S., Luthers,C.R.,
            Vo,A., Sheikh,S.Z. and Su,M.A.
  TITLE     Cutting Edge: Hypoxia Sensing by the Histone Demethylase UTX
            (KDM6A) Limits Colitogenic CD4+ T Cells in Mucosal Inflammation
  JOURNAL   J Immunol 212 (7), 1069-1074 (2024)
   PUBMED   38353647
  REMARK    GeneRIF: Cutting Edge: Hypoxia Sensing by the Histone Demethylase
            UTX (KDM6A) Limits Colitogenic CD4+ T Cells in Mucosal
            Inflammation.
REFERENCE   4  (bases 1 to 6892)
  AUTHORS   Li,C., Qin,T., Zhao,J., Jin,Y., Qin,Y., He,R., Wu,T., Duan,C.,
            Jiang,L., Yuan,F., Lu,H., Cao,Y. and Hu,J.
  TITLE     Kdm6a-CNN1 axis orchestrates epigenetic control of trauma-induced
            spinal cord microvascular endothelial cell senescence to balance
            neuroinflammation for improved neurological repair
  JOURNAL   Bone Res 12 (1), 19 (2024)
   PUBMED   38528029
  REMARK    GeneRIF: Kdm6a-CNN1 axis orchestrates epigenetic control of
            trauma-induced spinal cord microvascular endothelial cell
            senescence to balance neuroinflammation for improved neurological
            repair.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6892)
  AUTHORS   Liu,Y., Luo,Z., Xie,Y., Sun,Y., Yuan,F., Jiang,L., Lu,H. and Hu,J.
  TITLE     Extracellular vesicles from UTX-knockout endothelial cells boost
            neural stem cell differentiation in spinal cord injury
  JOURNAL   Cell Commun Signal 22 (1), 155 (2024)
   PUBMED   38424563
  REMARK    GeneRIF: Extracellular vesicles from UTX-knockout endothelial cells
            boost neural stem cell differentiation in spinal cord injury.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6892)
  AUTHORS   Xu,J., Burgoyne,P.S. and Arnold,A.P.
  TITLE     Sex differences in sex chromosome gene expression in mouse brain
  JOURNAL   Hum Mol Genet 11 (12), 1409-1419 (2002)
   PUBMED   12023983
REFERENCE   7  (bases 1 to 6892)
  AUTHORS   Blair,H.J., Reed,V., Gormally,E., Wilson,J.B., Novak,J.,
            McInnes,R.R., Phillips,S.J., Taylor,B.A. and Boyd,Y.
  TITLE     Positioning of five genes (CASK, ARX, SAT, IMAGE cDNAs 248928 and
            253949) from the human X chromosome short arm with respect to
            evolutionary breakpoints on the mouse X chromosome
  JOURNAL   Mamm Genome 11 (8), 710-712 (2000)
   PUBMED   10920247
REFERENCE   8  (bases 1 to 6892)
  AUTHORS   Grbavec,D., Lo,R., Liu,Y., Greenfield,A. and Stifani,S.
  TITLE     Groucho/transducin-like enhancer of split (TLE) family members
            interact with the yeast transcriptional co-repressor SSN6 and
            mammalian SSN6-related proteins: implications for evolutionary
            conservation of transcription repression mechanisms
  JOURNAL   Biochem J 337 (Pt 1) (Pt 1), 13-17 (1999)
   PUBMED   9854018
REFERENCE   9  (bases 1 to 6892)
  AUTHORS   Greenfield,A., Carrel,L., Pennisi,D., Philippe,C., Quaderi,N.,
            Siggers,P., Steiner,K., Tam,P.P., Monaco,A.P., Willard,H.F. and
            Koopman,P.
  TITLE     The UTX gene escapes X inactivation in mice and humans
  JOURNAL   Hum Mol Genet 7 (4), 737-742 (1998)
   PUBMED   9499428
REFERENCE   10 (bases 1 to 6892)
  AUTHORS   Greenfield,A., Scott,D., Pennisi,D., Ehrmann,I., Ellis,P.,
            Cooper,L., Simpson,E. and Koopman,P.
  TITLE     An H-YDb epitope is encoded by a novel mouse Y chromosome gene
  JOURNAL   Nat Genet 14 (4), 474-478 (1996)
   PUBMED   8944031
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL773547.6 and AL732451.8.
            
            On Mar 30, 2022 this sequence version replaced XM_006527595.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223971.18615.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-530               AL773547.6         105713-106242
            531-594             AL773547.6         106454-106517
            595-703             AL773547.6         142228-142336
            704-753             AL773547.6         151806-151855
            754-812             AL773547.6         160008-160066
            813-933             AL732451.8         6011-6131
            934-988             AL732451.8         17114-17168
            989-1023            AL732451.8         19915-19949
            1024-1117           AL732451.8         22095-22188
            1118-1244           AL732451.8         24956-25082
            1245-1343           AL732451.8         29220-29318
            1344-1563           AL732451.8         29451-29670
            1564-1698           AL732451.8         30229-30363
            1699-1854           AL732451.8         30821-30976
            1855-1944           AL732451.8         31524-31613
            1945-2046           AL732451.8         33007-33108
            2047-2442           AL732451.8         33961-34356
            2443-3221           AL732451.8         37258-38036
            3222-3351           AL732451.8         41090-41219
            3352-3457           AL732451.8         44777-44882
            3458-3663           AL732451.8         45484-45689
            3664-3728           AL732451.8         47202-47266
            3729-3803           AL732451.8         47340-47414
            3804-3952           AL732451.8         47816-47964
            3953-4067           AL732451.8         52402-52516
            4068-4255           AL732451.8         55099-55286
            4256-4397           AL732451.8         56202-56343
            4398-4524           AL732451.8         58289-58415
            4525-4695           AL732451.8         60630-60800
            4696-6892           AL732451.8         61880-64076
FEATURES             Location/Qualifiers
     source          1..6892
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 13.45 cM"
     gene            1..6892
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /note="lysine (K)-specific demethylase 6A"
                     /db_xref="GeneID:22289"
                     /db_xref="MGI:MGI:1095419"
     exon            1..530
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            531..594
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            595..703
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            704..753
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            754..812
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            813..933
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            934..988
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1023
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1117
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1118..1244
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1343
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1344..1563
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1564..1698
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1699..1854
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1855..1944
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1945..2046
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            2047..2442
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            2443..3221
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3222..3351
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3352..3457
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3458..3663
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3664..3728
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3729..3803
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3804..3952
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3953..4067
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            4068..4255
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            4256..4397
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            4398..4524
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            4525..4695
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            4696..6892
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5565..5570
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /note="hexamer: ATTAAA"
     polyA_site      5587
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /note="major polyA site"
     regulatory      5836..5841
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /note="hexamer: AATATA"
     polyA_site      5868
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
     regulatory      5985..5990
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /note="hexamer: AATACA"
     polyA_site      6006
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
     regulatory      6874..6879
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
                     /note="hexamer: AATAAA"
     polyA_site      6892
                     /gene="Kdm6a"
                     /gene_synonym="Utx"
ORIGIN      
        1 acaacaactt tgtgctggtg ccggggaagt ttgtgtctcc tacgaatccc ccccagagct
       61 cccgctcctc gcgcgctccg gccattcccg ccgaccctgc ctgtggctgc ccccttccca
      121 tccccgcgat gtgaccctac agccgagccg tcgccgctcc ggacccagtg gttccacagc
      181 ctctgctgcc tctgccttca cctctaccgc gttaggattt ttcgctgccg cctctcgcgg
      241 cagaggagga ggcagaaata aagttggtgt gccggtcttg tgcggagatt ggaggcgtcc
      301 ttgcgggctc cggcccggag agggggggtg tcggcgttgg agttgtgaat tcgctgcgtt
      361 tccatgaaat cctgcggagt gtcgctcgct accgccgccg ccgccgccgc cgccgccgct
      421 ttcggtgatg aggaaaagaa aatggcggcg ggaaaagcga gcggcgagag cgaggaggcg
      481 tcccccagcc tgacagcgga ggagagggag gcgctcggcg gactggacag ccgccttttc
      541 gggttcgtga ggtttcatga agatggcgcc aggatgaagg ccctgctggg caaggctgtt
      601 cgctgctacg aatctctaat cttaaaagct gaagggaaag tggagtctga tttcttttgt
      661 caattaggtc acttcaacct cttattggaa gattatccaa aagcattatc tgcataccag
      721 aggtactaca gtttacagtc tgattactgg aagaatgctg cctttttata tggtcttggt
      781 ttggtctact tccattacaa tgcatttcag tgggctatta aagcatttca ggaggtgctt
      841 tatgtcgatc ccagcttttg tcgagccaag gaaattcatt tacgacttgg gcttatgttc
      901 aaagtgaaca cagactatga gtctagttta aagcattttc agttagcttt ggttgactgt
      961 aatccctgca ctttgtccaa tgctgaaatt cagtttcaca ttgcccactt atatgaaacc
     1021 cagaggaagt atcattctgc aaaagaagct tatgagcaac ttttgcagac agaaaacctt
     1081 tctgcacaag taaaagcaac tattttacaa caattaggtt ggatgcatca cactgtggat
     1141 ctcctgggag ataaggccac caaggaaagt tatgctattc agtatctcca gaagtccttg
     1201 gaagcagatc caaattctgg ccagtcctgg tatttccttg gaaggtgcta ttcaagtatt
     1261 gggaaagttc aggatgcctt tatatcttac aggcaatcta ttgataaatc agaagcaagt
     1321 gcagatacat ggtgttcaat aggtgtgctc tatcaacagc aaaatcagcc tatggatgct
     1381 ttgcaagctt atatttgtgc tgtacaattg gaccacggtc atgctgcagc ctggatggat
     1441 ctaggcactc tctatgaatc ctgcaaccaa cctcaggatg ctattaaatg ctatttaaat
     1501 gcaactagaa gcaaaaattg tagtaatacc tctggacttg cagcacgaat taagtattta
     1561 caggctcagt tgtgtaacct tccacaaggt agtctacaga ataaaactaa attacttcct
     1621 agtattgagg aggcatggag cctaccaatc cccgcagagc ttacctccag gcagggtgcc
     1681 atgaacacag cacagcaggc atgtaaacct catcatccaa atactgaacc tgtattaggc
     1741 ctcagtcaaa caccaatttc acagcagtcc ttgccactac acatgattcc tcctagccaa
     1801 gtagatgacc tgtccagtcc tgccaagagg aaaagaacat ctagtccaac aaagaatact
     1861 tctgataatt ggagtggtgg caatgcacca cctccagtag aacaacaaac tcattcatgg
     1921 tgtttgacac cacagaaatt acagcacttg gaacagctcc gagcaaacag aaataattta
     1981 aatccagcac agaaactaat gctggaacag ctggaaagtc agtttgtctt aatgcagcaa
     2041 caccaaatga gacaaacagg agttgcacag gtacggccta ctggaattct taatgggcca
     2101 acagttgact catcactgcc tacaaactca gtttctggcc agcagccaca gcttcctctg
     2161 accagaatgc ctagtgtctc tcagcctgga gtccacactg cctgtcctag gcagactttg
     2221 gccaatggac ccttttctgc aggccatgtt ccctgtagca catcaagaac actgggaagt
     2281 acagacactg ttttgatagg caataatcat gtaacaggaa gtggaagtaa tggaaacgtg
     2341 ccttacctgc agcgaaacgc acccactcta cctcataacc gcacaaacct gaccagcagc
     2401 acagaggagc cgtggaaaaa ccaactatct aactccactc aggggcttca caaaggtccg
     2461 agttcacatt tggcaggtcc taatggtgaa cgacctctat cttccactgg gccttcccag
     2521 catctccagg cagctggctc tggtattcag aatcagaatg gacatcccac cctgcctagc
     2581 aattcagtaa cacagggggc tgctctcaat cacctctcct ctcacactgc tacctcaggt
     2641 ggacaacaag gcattacctt aaccaaagag agcaagcctt caggaaacac attgacggtg
     2701 cctgaaacaa gcaggcaaac tggagagaca cctaacagca ctgccagtgt tgagggactt
     2761 cctaatcatg tccatcaggt gatggcagat gctgtttgca gtcctagcca tggagattct
     2821 aagtcaccag gtttactaag ttcagacaat cctcagctct ctgccttgtt gatgggaaaa
     2881 gctaataaca atgtgggtcc tggaacctgt gacaaagtca ataacatcca cccaactgtc
     2941 catacaaaga ctgataattc tgttgcctct tcaccatctt cagccatttc cacagcaaca
     3001 ccttctccta agtccactga acagacaacc acaaacagtg ttaccagcct taacagccct
     3061 cacagtgggc tgcacacaat taatggagaa ggaatggaag aatctcagag ccccattaaa
     3121 acagatctgc ttctagttag ccacagacct agtcctcaga tcataccatc aatgtctgtg
     3181 tccatatatc ccagctcagc agaagttctg aaagcttgca ggaatctagg taaaaacggc
     3241 ctgtctaata gtagcattct gttggataaa tgtccgcctc caagaccacc atcctcacca
     3301 taccctccct tgccaaagga caagttgaat ccacctacac ctagtattta tttggaaaat
     3361 aaacgtgatg ctttctttcc tccattacat caattttgta caaacccaaa caaccctgtt
     3421 acagtaatac gtggccttgc tggagctctt aaattagact tgggactttt ctctactaaa
     3481 actttggtgg aagctaacaa tgaacatatg gtagaagtga ggacacagtt gttacaacca
     3541 gcagatgaaa attgggaccc tactggaacc aagaaaatct ggcactgtga aagtaataga
     3601 tctcatacta caattgctaa atatgctcag taccaggcct cctcattcca agaatcattg
     3661 agagaagaaa atgagaaaag aagtcaccat aaagaccact cagacagtga atctacatca
     3721 tcagataatt ctgggaaaag aagaaaagga ccctttaaaa ccattaagtt tgggaccaac
     3781 attgacctgt ctgatgacaa aaagtggaag ttacagctac atgagctgac taaacttcct
     3841 gccttcgtga gagttgtatc tgcaggaaat cttttaagcc acgttggtca tactatactg
     3901 ggcatgaaca cagttcaact atacatgaaa gttccaggaa gcagaacacc aggtcatcaa
     3961 gaaaataaca acttctgttc agttaatata aatattggcc caggtgactg tgaatggttt
     4021 gttgttcctg aaggctactg gggtgttttg aatgacttct gtgaaaaaaa taatttgaat
     4081 ttcttaatgg gttcttggtg gcccaacctt gaagatctat atgaagcaaa tgttccagtg
     4141 tataggttta ttcagcgacc tggagatctg gtctggataa atgctggcac tgttcattgg
     4201 gttcaagcta ttggctggtg caacaatatt gcttggaatg ttggtccact tacagcctgt
     4261 cagtataagt tagcagtgga acgttatgaa tggaacaagt tgcaaaatgt aaagtcaata
     4321 gtacccatgg ttcatctttc ctggaatatg gcacgaaata tcaaggtttc agatccaaag
     4381 ctttttgaaa tgattaagta ttgtcttctg agaacgctga agcaatgtca gacattgagg
     4441 gaagctctaa ttgctgcagg aaaagagatc atatggcacg ggcggacaaa agaagaacca
     4501 gctcattatt gtagtatttg tgaggtggag gtttttgatc tgctttttgt cactaatgag
     4561 agtaattctc gaaaaaccta catagtacat tgccaagatt gtgcacgaaa aacaagtggg
     4621 aatctggaaa attttgtggt gctagaacag tacaaaatgg aggatctgat gcaagtctat
     4681 gaccaattta cattagctcc tccattacca tccgcctcat cttgatattg ttccatggac
     4741 attaaacatg agaccttttc tgctattcag aaagtaaccc agttctgcac cactgctatt
     4801 tgtagctatc tcgtaaggct gctggctgaa aactgtgtct atgcaacctt ccaagtgtgg
     4861 agtgtcaacc aactggacgg gagagtactg ctcctatgcc aggactctcg taaagctaat
     4921 tagctgaact tcagagaaaa aaaaaagaat aataattacc acgttttgta tatatctgac
     4981 aaaactggca acatcataaa gactactgac ttgaagacaa cctcttttat atttctcgat
     5041 ttctgggcta atgaatttgt tttcacctat cttttccctt tcagaatttt attcgggggg
     5101 gaaaataact agcctagctg gtcatttctt tgtaaggtag ttagcaatat ttagtctttc
     5161 tttggtcacc tttttttttt taatgtgaaa agttaagtaa gaaacttttt ttactgcttt
     5221 tatgaatttc tgtcttgttt tgaaactatg atcgttataa ttttggttcc caaataaaac
     5281 atttaaaaaa aataattaac agcaacgtca caaagataat ggattgcaca tagactaaga
     5341 aataaacttc agaattgtga ttttttttgt ttctaatctt gatgtaaatt tacactattt
     5401 ataaatacat atttattgcc tgaaaatatt tgtgaatgga atgctgttat tttttccaga
     5461 tttacctgcc attgaaattt taaggagttc tgtaatttca aacactactc ctattacatt
     5521 ttctatgtgt aaataaaact gcttagcctt gtacagaaac ttttattaaa attgtttaat
     5581 gtttaaagag ttttctattg tttgagtttt aaaaagaatt tatgtacagt gcccaatttt
     5641 tgttcacttt tcaaatctga ttatatatat tttatatata cttatgtctg tatatataat
     5701 atatatagaa atctagatat atgtataaag atttagaatt tgaatttttc ttgttttaag
     5761 tttcacatct atggtagatt tttgaggtgt ctactgtaaa gtattgctca caaaaagtat
     5821 gattattttt aaagaaatat atatggtatg tatcttcaag acctaaaatg tcagactggt
     5881 ttattgttaa attgcaacta ctgcaattac agacaaaaaa aatctgccaa atgtagtata
     5941 atagaaaaca tagtgattga acttaaaact ttaaagggag ttttaataca ggcttttcaa
     6001 atcctataca tgactcatca ttttttatga ggaaaaaatt tccaggatga agggccgtgt
     6061 tttagaatac aaattaattt aagaggctta ttttttaatg ttaggcaatt ttgaaatatc
     6121 atgcctttct gcatgcatga cagtggagtg ggattatgtt accattcaca gattaccgct
     6181 agttaatgct aggatttttt tccttctttt tttttttttt tttttttttt taaataatgg
     6241 caccttccat ttgtaccatt ttcttaagta ctttgggaca catttttatt ttagaatata
     6301 gttcttaaga attttccacc aaattaggga agaagaatag agaatgctgt aagtaaagag
     6361 tgggtggctg ggttggttgg ttcatatcta gtcttacctg ctggaccatt gtggtgaata
     6421 tattatcttt tcagatattt tttagagtat gtcttaggag tatttcaagg actgaaagta
     6481 tagagatatt ttattcagtt ggttaataac ttagtaaaca ttgaatgtct attggcattc
     6541 atttcttatt atttcaggaa gcaattattc caaatcattt atccaaatac tgattcagct
     6601 gtttaactac aaatatttta aatggttaat ttgtaaaaat aagctatcaa gaaagtccaa
     6661 cagaatgaaa taaggaagta aggcttttgt gaataaaaat tctaagccaa ccttaaagga
     6721 acaaaactac acctaactgt tcttactttg ttctagtttt ttgttctagt cttactgaca
     6781 tatcttttga gtgactatgt taaggtaaag ttttgtcaag atgaatgtgt tgtcttacat
     6841 ctatataaga gaaatttatg taatccaagt ttgaataaat atatcaagat ta
//
