LOCUS       NM_134090               1414 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein
            retention receptor 3 (Kdelr3), mRNA.
ACCESSION   NM_134090
VERSION     NM_134090.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1414)
  AUTHORS   Altenhofen,D., Khuong,J.M., Kuhn,T., Lebek,S., Gorigk,S.,
            Kaiser,K., Binsch,C., Griess,K., Knebel,B., Belgardt,B.F.,
            Cames,S., Eickelschulte,S., Stermann,T., Rasche,A., Herwig,R.,
            Weiss,J., Vogel,H., Schurmann,A., Chadt,A. and Al-Hasani,H.
  TITLE     E96V Mutation in the Kdelr3 Gene Is Associated with Type 2 Diabetes
            Susceptibility in Obese NZO Mice
  JOURNAL   Int J Mol Sci 24 (1), 845 (2023)
   PUBMED   36614300
  REMARK    GeneRIF: E96V Mutation in the Kdelr3 Gene Is Associated with Type 2
            Diabetes Susceptibility in Obese NZO Mice.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1414)
  AUTHORS   Tamplin,O.J., Cox,B.J. and Rossant,J.
  TITLE     Integrated microarray and ChIP analysis identifies multiple Foxa2
            dependent target genes in the notochord
  JOURNAL   Dev Biol 360 (2), 415-425 (2011)
   PUBMED   22008794
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC117806.11 and AK136991.1.
            
            On Nov 25, 2009 this sequence version replaced NM_134090.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024420.1, AK136991.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                AC117806.11        48460-48476
            18-818              AK136991.1         2-802
            819-1412            AK136991.1         804-1397
            1413-1414           AC117806.11        59790-59791
FEATURES             Location/Qualifiers
     source          1..1414
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 37.76 cM"
     gene            1..1414
                     /gene="Kdelr3"
                     /note="KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum
                     protein retention receptor 3"
                     /db_xref="GeneID:105785"
                     /db_xref="MGI:MGI:2145953"
     exon            1..233
                     /gene="Kdelr3"
                     /inference="alignment:Splign:2.1.0"
     CDS             143..787
                     /gene="Kdelr3"
                     /note="KDEL receptor 3; KDEL endoplasmic reticulum protein
                     retention receptor 3"
                     /codon_start=1
                     /product="ER lumen protein-retaining receptor 3"
                     /protein_id="NP_598851.2"
                     /db_xref="CCDS:CCDS27642.1"
                     /db_xref="GeneID:105785"
                     /db_xref="MGI:MGI:2145953"
                     /translation="MNVFRILGDLSHLLAMILLLVKIWRSKSCAGISGKSQILFALVF
                     TTRYLDLFSNFISIYNTVMKVVFLLCAYVTVYMIYWKFRKTFDIENDTFRLEFLLVPV
                     TGLSFLVNYSYTPMEVLWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRL
                     LYLANWIRRYQTENFYDQISVVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPVPV"
     exon            234..334
                     /gene="Kdelr3"
                     /inference="alignment:Splign:2.1.0"
     exon            335..493
                     /gene="Kdelr3"
                     /inference="alignment:Splign:2.1.0"
     exon            494..746
                     /gene="Kdelr3"
                     /inference="alignment:Splign:2.1.0"
     exon            747..1414
                     /gene="Kdelr3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1394..1399
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kdelr3"
                     /note="hexamer: AATAAA"
     polyA_site      1414
                     /gene="Kdelr3"
                     /note="major polyA site"
ORIGIN      
        1 ggcgggagcg cgccagcaag gaggcgcggc accggcctgg ggcaccgcga ggagcaggga
       61 cggggacgtg gcagcgcccc gcgcaacaga aagttccctg ggaagttctg cgcgacacgg
      121 cgcgggagcg gcgggcggga ccatgaacgt gttccgaatc ctcggggacc tgagccacct
      181 cctggctatg atcttgctcc tggtgaagat ctggaggtcc aagagctgcg ccggcatctc
      241 tggaaagagc cagattcttt tcgctttggt ctttaccacc aggtacctgg acctcttctc
      301 gaacttcatc tccatctaca acacagtgat gaaggtggtt ttcctcctct gtgcctatgt
      361 cacagtgtac atgatctatt ggaagttccg gaaaacgttt gacattgaaa atgacacatt
      421 ccggctggag ttcctcctgg tccccgtgac tggcctttcc tttctggtga actacagtta
      481 cacgccgatg gaggtcctct ggaccttctc catctatctg gagtcagtgg ctatcctgcc
      541 acagctcttc atgatcagca agaccggaga ggctgagacc atcaccactc actacctgtt
      601 cttcctgggg ctctatcggc tcctctatct ggccaactgg atcaggcggt accagacaga
      661 gaacttctat gaccagatct cagtagtgtc tggagttgtt caaaccatct tttactgtga
      721 cttcttctac ttgtatgtga ccaaagtcct taaaggaaag aaattaagcc tcccggtgcc
      781 agtttgaaga gaagggccac ccctatggca gctaaagcaa accatccgga tcactgcttc
      841 atgacttcaa gccaagactt gggacttcat gttagagtga ctggtgtgaa tttgagcaaa
      901 gcaccatctt gggataaacg gcagcacctc cctaatccac catggataga atgggatacc
      961 tagcccatct gcccaaggat ggtgccctac aagtgccaag tgaagagaag cagtagatac
     1021 ctccgtgagt ggctcaactc cttgcttcct taggactata caactcatgc ccagggctgg
     1081 gaagatccat tcagagaacc tccctaggtc agcgtgctga actcgagcca catgtccacc
     1141 tggcctgcaa gctgtaagca gtccaaataa ccagctctgc caagtgctta ggactgctta
     1201 gctcacttgt tagctgagat ggacaccatg gccactgtgt aaatccattc tgtgctaaga
     1261 accaccaatg tagccttccc ctcccagcct gaggtgctaa atagaatgcc taatacactc
     1321 accctgctta atgttttcac tgcttggagg aaaacattaa gagtacactt aaactctttt
     1381 taagttttaa tgtaataaaa aattcacacc ttta
//
