LOCUS       NM_027782               1734 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus potassium channel tetramerisation domain containing 6
            (Kctd6), transcript variant 2, mRNA.
ACCESSION   NM_027782
VERSION     NM_027782.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1734)
  AUTHORS   Lange,S., Perera,S., Teh,P. and Chen,J.
  TITLE     Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1
            (sAnk1.5) protein turnover
  JOURNAL   Mol Biol Cell 23 (13), 2490-2504 (2012)
   PUBMED   22573887
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CX239507.1, AK082924.1 and CJ248971.1.
            
            On Apr 9, 2015 this sequence version replaced NM_027782.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Variants 1-3 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CX239507.1, AK017384.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-608               CX239507.1         1-608
            609-1705            AK082924.1         542-1638
            1706-1734           CJ248971.1         439-467
FEATURES             Location/Qualifiers
     source          1..1734
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 4.76 cM"
     gene            1..1734
                     /gene="Kctd6"
                     /gene_synonym="5430433B02Rik"
                     /note="potassium channel tetramerisation domain containing
                     6"
                     /db_xref="GeneID:71393"
                     /db_xref="MGI:MGI:1918643"
     exon            1..262
                     /gene="Kctd6"
                     /gene_synonym="5430433B02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            263..332
                     /gene="Kctd6"
                     /gene_synonym="5430433B02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             306..1019
                     /gene="Kctd6"
                     /gene_synonym="5430433B02Rik"
                     /codon_start=1
                     /product="BTB/POZ domain-containing protein KCTD6"
                     /protein_id="NP_082058.1"
                     /db_xref="CCDS:CCDS26812.1"
                     /db_xref="GeneID:71393"
                     /db_xref="MGI:MGI:1918643"
                     /translation="MDNGDWGYMMSDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGG
                     DFPTARDPQGNYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLI
                     QCLNDPRPLYPMDTFEEVVELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYF
                     TKWNKHMMDTRDCQVSFTFGPCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERAN
                     ENTVEHNWTFCRLARKTDD"
     exon            333..1716
                     /gene="Kctd6"
                     /gene_synonym="5430433B02Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1690..1695
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kctd6"
                     /gene_synonym="5430433B02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1709
                     /gene="Kctd6"
                     /gene_synonym="5430433B02Rik"
                     /note="major polyA site"
ORIGIN      
        1 tccggcttcc cggccttcgc cccgcgccgc cgataggggg cgtccgcgtt ctcggcgccg
       61 cgactctgct gagaaggcgc cgcccgcgcc gggcagctgg agccgcaact ccgggctccg
      121 gctcactcgt cccctctgcc gccgccgccg ccgccgccgc caccgccgcc gctgccgccg
      181 cggggcgcgg gctcgctcgt ccccgcgctc gcgctctcgg gccgccggcg tctcccggcc
      241 gggtcgcctc cgcgctcgtg caagttccct ggctcctgag ctctgaggac gcagtgctgg
      301 agcagatgga taatggggac tggggctata tgatgagtga cccagtcaca ttaaatgtag
      361 gtggacactt gtacacgaca tcgcttacca cgttgacacg ctacccggat tctatgcttg
      421 gagctatgtt tgggggtgac ttccccacag cccgagaccc tcaaggcaat tacttcattg
      481 atcgagacgg accgctcttc cgctatgtcc ttaacttcct acggacttca gaactgacac
      541 tccccctgga ctttaaggag tttgatctgc ttcggaaaga ggctgatttc taccagatcg
      601 aacccttgat tcagtgtctc aatgacccca ggcctctgta tcctatggat acttttgaag
      661 aagtcgtaga gctgtctagc actcggaagc tttctaaata ttccaatccg gtggccgtca
      721 tcatcaccca gttaaccatc accacaaagg tccactcctt actcgaaggc atctcaaact
      781 atttcaccaa gtggaataag cacatgatgg acaccagaga ctgccaggtc tccttcacct
      841 ttggaccgtg cgattaccac caggaagtct ctctccgggt ccatctgatg gagtacatca
      901 cgaagcaagg tttcacgatc cgcaatactc gggtgcatca catgagcgag cgggccaatg
      961 agaacacagt agagcacaac tggactttct gtagactggc ccgcaagacg gacgactgac
     1021 tgctggccag ccctcagaga acttcctgca agctcacgtt ttgggacatg gaagagactg
     1081 ttgttgggtt ttagtgtggg ccctcttttt ttttttaatt ttttgattca gtctttgtat
     1141 ttatttgaag gcattgagga ccagaaggaa gttttgtgtg tgagcagtct cctccctgtt
     1201 ttgttcccaa gtatgcatgt gcctgttccg agtctctaga aacctttttt ataaaaagag
     1261 atctgaaaat cattatggta tataatctac ccttaacagt gataaaatga tttctgagaa
     1321 cgtggttcct gactcgactg gaaggctaaa aacaggaata aaagattaaa gagggtattc
     1381 atgatgtctt tgagaaaaat cagaatatca tgtagggcga cctagtttcc agaccagtag
     1441 gcagtattgt ggtgttaaag gaagactggc ccagtcatct gagggtactt gttaaggact
     1501 gctttctaca gttttgacaa ctgtttcttt ctatgcatat aaatcaagca accaaatatc
     1561 tgtagccatg gaaatgtctg actagaaata tttatattgg attctcaata caaaatgtcc
     1621 ctgtggtaga aaccttatgc ctggtacagt ttcattccca aggtactgtc taccaggaaa
     1681 gaaaaatcta ataaaaaatg gaatatgaat attaaaaaaa aaaaaaaaaa aaaa
//
