LOCUS       NM_027008               2457 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus potassium channel tetramerisation domain containing 5
            (Kctd5), mRNA.
ACCESSION   NM_027008
VERSION     NM_027008.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2457)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2457)
  AUTHORS   Hirano,A., Nakagawa,T., Yoshitane,H., Oyama,M., Kozuka-Hata,H.,
            Lanjakornsiripan,D. and Fukada,Y.
  TITLE     USP7 and TDP-43: Pleiotropic Regulation of Cryptochrome Protein
            Stability Paces the Oscillation of the Mammalian Circadian Clock
  JOURNAL   PLoS One 11 (4), e0154263 (2016)
   PUBMED   27123980
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2457)
  AUTHORS   Ahmed,S.M., Theriault,B.L., Uppalapati,M., Chiu,C.W., Gallie,B.L.,
            Sidhu,S.S. and Angers,S.
  TITLE     KIF14 negatively regulates Rap1a-Radil signaling during breast
            cancer progression
  JOURNAL   J Cell Biol 199 (6), 951-967 (2012)
   PUBMED   23209302
REFERENCE   4  (bases 1 to 2457)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK052960.1, AK143644.1 and AI606105.1.
            
            On Jun 10, 2009 this sequence version replaced NM_027008.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK052960.1, SRR1660815.149639.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                AK052960.1         3-35
            34-2081             AK143644.1         2-2049
            2082-2443           AK052960.1         2088-2449
            2444-2457           AI606105.1         166-179
FEATURES             Location/Qualifiers
     source          1..2457
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.22 cM"
     gene            1..2457
                     /gene="Kctd5"
                     /gene_synonym="2610030N08Rik; mKIAA0176"
                     /note="potassium channel tetramerisation domain containing
                     5"
                     /db_xref="GeneID:69259"
                     /db_xref="MGI:MGI:1916509"
     exon            1..309
                     /gene="Kctd5"
                     /gene_synonym="2610030N08Rik; mKIAA0176"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..762
                     /gene="Kctd5"
                     /gene_synonym="2610030N08Rik; mKIAA0176"
                     /codon_start=1
                     /product="BTB/POZ domain-containing protein KCTD5"
                     /protein_id="NP_081284.2"
                     /db_xref="CCDS:CCDS28473.1"
                     /db_xref="GeneID:69259"
                     /db_xref="MGI:MGI:1916509"
                     /translation="MAENHCELLPPAPSGLGAGLGGGLCRRCSAGMGALAQRPGGVSK
                     WVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPV
                     LNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKISQMPVKHVYRV
                     LQCQEEELTQMVSTMSDGWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTTS
                     EPSEKAKILQERGSRM"
     exon            310..418
                     /gene="Kctd5"
                     /gene_synonym="2610030N08Rik; mKIAA0176"
                     /inference="alignment:Splign:2.1.0"
     exon            419..510
                     /gene="Kctd5"
                     /gene_synonym="2610030N08Rik; mKIAA0176"
                     /inference="alignment:Splign:2.1.0"
     exon            511..606
                     /gene="Kctd5"
                     /gene_synonym="2610030N08Rik; mKIAA0176"
                     /inference="alignment:Splign:2.1.0"
     exon            607..732
                     /gene="Kctd5"
                     /gene_synonym="2610030N08Rik; mKIAA0176"
                     /inference="alignment:Splign:2.1.0"
     exon            733..2457
                     /gene="Kctd5"
                     /gene_synonym="2610030N08Rik; mKIAA0176"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1544
                     /gene="Kctd5"
                     /gene_synonym="2610030N08Rik; mKIAA0176"
                     /note="major polyA site"
     regulatory      2419..2424
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kctd5"
                     /gene_synonym="2610030N08Rik; mKIAA0176"
                     /note="hexamer: AATAAA"
     polyA_site      2436
                     /gene="Kctd5"
                     /gene_synonym="2610030N08Rik; mKIAA0176"
                     /note="major polyA site"
ORIGIN      
        1 gtattaaaga acggacgctt ccggcgaagg gccgctgtgg cggggcttgt taggatcatg
       61 gcggagaatc actgcgagct gctgccgccg gctccgagcg gcctcggggc ggggctgggg
      121 ggcggcctgt gccgccgctg cagcgctggg atgggcgccc tggctcagcg ccccggtggc
      181 gtgtccaagt gggtccggct caacgtcggc ggcacctact tcctcaccac ccggcagacg
      241 ctgtgccggg acccgaagtc tttcctgtac cgcttgtgcc aggcggaccc cgacctagat
      301 tcggacaagg atgaaacggg tgcctattta atcgacagag atcccaccta ctttggacct
      361 gtactgaact acttgagaca tggaaagctg gttattaaca aagacctcgc agaggaagga
      421 gtgttggaag aagcagaatt ttacaatatc acctcactaa taaaacttgt aaaggacaaa
      481 attagagaac gagacagcaa aatatcccag atgccagtga agcatgtgta ccgtgtgctg
      541 cagtgccagg aggaggagct cacacagatg gtatccacaa tgtcagacgg ctggaagttt
      601 gagcagctgg tcagcattgg ctcctcttac aactatggaa atgaagacca ggctgagttc
      661 ctctgtgtgg tttccaagga gctgcacaac actccatacg gcacaaccag tgagccaagc
      721 gagaaagcca agattttgca agaacggggc tcaaggatgt gaggaatgct gagagttgaa
      781 gaaatgattt tcttttcccc aagataaagt gaaccgccat gtgcaaaaag catggctgtg
      841 agaagaaacc tgcttttgat catttctcta gaggtctggg tgtggatcct tttttgcctc
      901 agatgtgggt ggcgagagac agcccagctg tcaggccagt cgtccccacc cggagcagct
      961 agggctgggt tggcagtctc tggtctcact attctttctg agtgctacgt gggactgagg
     1021 caggatgctg ctaaccagcc cgtgcattcc tgaagatgat ttgaaggaca gggtccttgg
     1081 tgctacacac agtctgcaac aagcagcctg gaccttgcca ggagggaggg gcagccgccg
     1141 caactcctgt ccagtgcact gtggctttgg gggtgggtgc ctgctcatca ctgactgagc
     1201 accaggcgca catccttgag tcagggaggc tgctctgcct ccaggcatga ttggttgatt
     1261 tctctcgacc tcagctgagg ctcctgacaa aggtggcctc cacgttatca ctacttctgg
     1321 gcaccacccc tggacattac tccttcagag ccaggctctt gttctggcct gtcagcttgg
     1381 cccaggatca tcaaggcttc ttaatttgta ttttccaggc aagaggactt tgtatccctt
     1441 ttttaaagtg tggatagacc acccggtgtt tatactcttt agaaatgcct aaaagtgttg
     1501 ctacattttg gattgatctg ttaaatcatt tatgctccca taaatagagg ttttgcctca
     1561 tatgtctcgc ctgtgggctc atgggggagc tggcgcctac cagtgccttt gttgtgcctg
     1621 ggatagaggc tggggtggga ggcctgtcca cctggcttct ggaactgaca ctccaggtca
     1681 tgttaagcat tcaggatgtt tacagtgcaa acatgtctcc ttctcactgg ctctcatttc
     1741 cttgtataac tatgcagttc ttctctcgta tttctggagt gtttgggact ttgcacaatt
     1801 tgcatgggct ctgttcatct gatacgacat tggagctgct aaggttcctg cagaggctgc
     1861 gcctgctggc ttgaaacaga ccttctcagc tggttagggg attgtagcag gccacaaact
     1921 tggctcaagc aagcaagctc tgtgcttctt gaccttccca agggagctgt gcaaactgac
     1981 cactatggct gcccatgtgc aggccagggc ctctgacact gcttgtttca aatgcttccg
     2041 gaaacttctt gcctagaccc tcttccttct cctctgccag taactgatta gtcaagttct
     2101 ccagcatcta ggaccgacct cctcctttcc taaggtctgt tgtatgttgt taaggtgtgg
     2161 cttaatcact ctggggcagt agctctgctg ttggccatgg ggatgctctg gggagtggct
     2221 ggacactcag cattgcttca tttatgactt tgacaataga taggcttctg ggggtttttg
     2281 tttctgtttt tttaatttaa tgatattaaa acttaattca ctaaaatcct aaggggatat
     2341 ttatactttt atactttttt aggtatccat attttatcag cttaccgttt aatgcctaag
     2401 tttcccctgg aaatagtaaa taaaattgtg tatttatgac tgtgttcagc aactgtg
//
