LOCUS       NM_026214               3015 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus potassium channel tetramerisation domain containing 4
            (Kctd4), mRNA.
ACCESSION   NM_026214
VERSION     NM_026214.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3015)
  AUTHORS   Puelles,L. and Hidalgo-Sanchez,M.
  TITLE     The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic
            Organizer
  JOURNAL   Int J Mol Sci 24 (11), 9769 (2023)
   PUBMED   37298722
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3015)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3015)
  AUTHORS   Boyle,M.P., Bernard,A., Thompson,C.L., Ng,L., Boe,A., Mortrud,M.,
            Hawrylycz,M.J., Jones,A.R., Hevner,R.F. and Lein,E.S.
  TITLE     Cell-type-specific consequences of Reelin deficiency in the mouse
            neocortex, hippocampus, and amygdala
  JOURNAL   J Comp Neurol 519 (11), 2061-2089 (2011)
   PUBMED   21491433
REFERENCE   4  (bases 1 to 3015)
  AUTHORS   Quina,L.A., Wang,S., Ng,L. and Turner,E.E.
  TITLE     Brn3a and Nurr1 mediate a gene regulatory pathway for habenula
            development
  JOURNAL   J Neurosci 29 (45), 14309-14322 (2009)
   PUBMED   19906978
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK004465.1, BC028748.1, AK017592.1, AK032624.1, AK032314.1 and
            BB427231.1.
            
            [WARNING] On Oct 28, 2024 this sequence was replaced by
            NM_026214.4.
            
            On Aug 5, 2004 this sequence version replaced NM_026214.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY151198.1, AK008741.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849387, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-338               AK004465.1         13-350
            339-1421            BC028748.1         54-1136
            1422-1801           AK017592.1         1153-1532
            1802-1813           BC028748.1         1515-1526
            1814-2572           AK032624.1         1552-2310
            2573-3003           AK032314.1         2280-2710
            3004-3015           BB427231.1         263-274
FEATURES             Location/Qualifiers
     source          1..3015
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 40.3 cM"
     gene            1..3015
                     /gene="Kctd4"
                     /gene_synonym="2210017A09Rik"
                     /note="potassium channel tetramerisation domain containing
                     4"
                     /db_xref="GeneID:67516"
                     /db_xref="MGI:MGI:1914766"
     exon            1..195
                     /gene="Kctd4"
                     /gene_synonym="2210017A09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            196..3015
                     /gene="Kctd4"
                     /gene_synonym="2210017A09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             389..1168
                     /gene="Kctd4"
                     /gene_synonym="2210017A09Rik"
                     /codon_start=1
                     /product="BTB/POZ domain-containing protein KCTD4"
                     /protein_id="NP_080490.3"
                     /db_xref="CCDS:CCDS27282.1"
                     /db_xref="GeneID:67516"
                     /db_xref="MGI:MGI:1914766"
                     /translation="MERKIIRREKEREYEGRHNSVEDAEQGKNCKSTLMTLNVGGYLY
                     ITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLRNGELLLPE
                     GFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPRETTFLEITDNHDRSQGLRIFCN
                     APDFISKIKSRIVLVSKSRLDGFPEEFSVSSNIIQFKYFIKSENGTRLVLKEDNTFVC
                     TLETLKFEAIMMALKCGFRLLTSLDCSKGSIVHSDALHFIK"
     regulatory      1835..1840
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kctd4"
                     /gene_synonym="2210017A09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1863
                     /gene="Kctd4"
                     /gene_synonym="2210017A09Rik"
                     /note="major polyA site"
ORIGIN      
        1 gagatccatt tgcatgtgga cacctttaag gatgattcca actctagcta catcacaacc
       61 aggcggctag ttccgaggat tctgacccga tctagacttt tgaaataacc ctcttattca
      121 caaatcactc ctccatctac catctttgaa aaagaagaga agtacttcta ctaatcgcat
      181 gcgtctgtct aaaagaaagc tcctgcatgc atagctgaca cgccacctac tgcaaaaccc
      241 agctgccagc gcaggcggtg ctaccagcat ttcattgcat cgccaggctg ggaaggaata
      301 aaggcgtgct tgtgtggtag tgtttctttt ttaaaaggaa aaaaaaatct ccaagccaag
      361 aagaacaagc tgaaatagca tcttgaaaat ggagcgtaaa ataatcagaa gagaaaagga
      421 aagggagtac gaagggaggc acaacagcgt ggaagatgcc gagcaaggca agaactgcaa
      481 atccacgctg atgaccctca acgttggtgg atatttatat attactcaaa agcagacact
      541 gaccaagtac ccagacactt tccttgaagg tatcgtaaat gggaaaatcc tctgtccatt
      601 cgatgctgat ggccattact tcatagacag ggacgggctt ctcttcaggc atgtcctaaa
      661 cttcctacga aatggagaac ttctactacc cgaaggattt cgagaaaatc aacttcttgc
      721 tcaagaagca gaattcttcc agctcaaggg gctggcagag gaggtgaaat ccaggtggga
      781 aaaagaacag ctgacccccc gagagactac tttcttggaa ataacagata atcacgatcg
      841 ctcacaagga ctgagaatct tctgtaatgc tcctgatttc atatcaaaaa taaaatctcg
      901 cattgttctg gtatccaaaa gcaggctgga tgggtttcca gaggagttct ctgtgtcgtc
      961 aaatatcatt caatttaaat acttcatcaa gtctgagaac ggcactcgac ttgtactaaa
     1021 ggaagacaac acctttgtct gcaccttgga aactcttaag tttgaggcca taatgatggc
     1081 tttaaaatgt gggtttagac tgctgactag cctggactgc tccaaagggt caattgttca
     1141 cagcgatgca cttcatttta tcaagtaatt acctgtctca tgaacaaagg caacaagcat
     1201 gcagccagca agcttcagaa gccacagaat caaaggcatc ccaaacaacg tgcccagcca
     1261 gctagtccag agcccggctg ctaagcaagt actgtgagct aacggtatgt aaatctatca
     1321 ctaaagatgt ccttctctgg ggtgttctgc catcacattt ccaccgacag tgaagctgtg
     1381 gtcttctaaa ctgtaaataa agacaatgct tttgctattt attttttttt ttttttccct
     1441 taagctgtct ttcaatgaga atgtcttggg tacttcatct atcattcact actgcaaatg
     1501 ctaacaacat acgattcaaa atcttttcta cttaagagca aaaatccatg aagaagatga
     1561 actggtttat aaaataaaca tggagagcaa aataaatgta cagagctacc taaagcaggg
     1621 gtaacagtga atcaaaatgt gactgtaaaa cacattcgag ctactgattt gacttttaaa
     1681 atagcaggca ccaaaagctt tattatagct cctgtatttc atactagaat tatggctaaa
     1741 ttgatatttt gctgaaaatt tctaggaaac tgcttgataa caataaaaaa taaataaaag
     1801 cattgctagc ttctctgctt gtattaatga ttgcaataaa agttacatgt gtcactttaa
     1861 aaacgaatag taccacttga tgactgtgca cggtattctg cattcatgca attaactgtc
     1921 aggctattgc gccttgctga tcagcaaggg acagaaatta gccaccactt tccagtacag
     1981 cacagcatgg gtggcctggt cccagctgag tgcagggtgt gcgaacggaa gagcctattt
     2041 cacaatcact ctatgctcag ttttcaagct caaaatgtta aatgaacatt atttaacaac
     2101 actcttagag aagaacttta ctgatctttt aaaatctttt atgtaaaaaa aagtccttca
     2161 aaatttcata ctaaaaccta acaaagtcac caccaccaac tactcaattt ccgttctgct
     2221 acactaaaat atctgttctg atgctaaacc tcaaaatcac aaagttgtgc ggattatttc
     2281 tatttcatgc taacatttac agaaatttta aactttattt tatgaatggc tgtttaagga
     2341 ctattctcct agctaaactc taaatgtgag tgcccactta tgttgcaaag agcacctgca
     2401 ccactcctgt ggcttcacct acatcattcc taatagtttc taagaacaaa ttgtcttaag
     2461 tttaaaataa acaagctgga agtggtgatt catgtttgaa tccttccagt tgaggcagga
     2521 ggattaacac atgtttgagg ccagcaaggg ttactatgtg aggctctatc tcaaaaaaag
     2581 caaaaagaaa aaaaaaggag gcagggaagc aatcatggaa actaacaact ataatccaac
     2641 cttattaaat aaaccaaata acctgttgat tatcttggct gagtttaaat agttaatcat
     2701 atattataac attttggtta catataaaat ttagaatgag gctcactatt aattattatt
     2761 aactataact gacttttact tacaaaatct aaggtaatat aaaagttgcc tatacagact
     2821 aaaagaaata aatcctttaa aggtactgtg caaacaaagt ccttcaaaaa tttatactaa
     2881 aacaacactc aatgtcaact acatactttt ctcagatgtc acattaagaa aaaaaatgct
     2941 ttgccttatg tatcaaattt tcttaatgag ctatatatgg cttaatcagg acttacaggg
     3001 actattgaaa caatt
//
