LOCUS       NM_026200               4496 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus potassium channel, subfamily V, member 1 (Kcnv1),
            mRNA.
ACCESSION   NM_026200
VERSION     NM_026200.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4496)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4496)
  AUTHORS   Harrell,M.D., Harbi,S., Hoffman,J.F., Zavadil,J. and Coetzee,W.A.
  TITLE     Large-scale analysis of ion channel gene expression in the mouse
            heart during perinatal development
  JOURNAL   Physiol Genomics 28 (3), 273-283 (2007)
   PUBMED   16985003
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ151712.1, AK139482.1 and AK034091.1.
            
            On Sep 3, 2009 this sequence version replaced NM_026200.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK034091.1, SRR1660811.151837.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-164               CJ151712.1         2-165
            165-3302            AK139482.1         1-3138
            3303-4496           AK034091.1         3196-4389
FEATURES             Location/Qualifiers
     source          1..4496
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 17.25 cM"
     gene            1..4496
                     /gene="Kcnv1"
                     /gene_synonym="2700023A03Rik; vibe"
                     /note="potassium channel, subfamily V, member 1"
                     /db_xref="GeneID:67498"
                     /db_xref="MGI:MGI:1914748"
     exon            1..764
                     /gene="Kcnv1"
                     /gene_synonym="2700023A03Rik; vibe"
                     /inference="alignment:Splign:2.1.0"
     CDS             295..1806
                     /gene="Kcnv1"
                     /gene_synonym="2700023A03Rik; vibe"
                     /note="neuronal potassium channel alpha subunit; potassium
                     channel Kv8.1 homolog; voltage-gated potassium channel
                     subunit Kv8.1"
                     /codon_start=1
                     /product="potassium voltage-gated channel subfamily V
                     member 1"
                     /protein_id="NP_080476.2"
                     /db_xref="CCDS:CCDS27459.1"
                     /db_xref="GeneID:67498"
                     /db_xref="MGI:MGI:1914748"
                     /translation="MDLSPRNRPLLDSSSLDSGSLTSLDSSVFCSEGEGEPLALGDCF
                     TVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRLGALAAAPSPLELCDDANPVDN
                     EYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFR
                     RKELSETLDFKKDTDDQESQHESEQDFSKGPCPTVRQKLWDILEKPGSSTAARIFGVI
                     SIIFVAVSIVNMALMSAELSWLNLQLLEILEYVCISWFTGEFVLRFLCVKDRCHFLRK
                     VPNIIDLLAILPFYITLLVESLSGSHTTQELENVGRLVQVLRLLRALRMLKLGRHSTG
                     LRSLGMTITQCYEEVGLLLLFLSVGISIFSTIEYFAEQSIPDTTFTSVPCAWWWATTS
                     MTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQ
                     REALKKLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF"
     exon            765..1294
                     /gene="Kcnv1"
                     /gene_synonym="2700023A03Rik; vibe"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..4496
                     /gene="Kcnv1"
                     /gene_synonym="2700023A03Rik; vibe"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2065..2070
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kcnv1"
                     /gene_synonym="2700023A03Rik; vibe"
                     /note="hexamer: AATATA"
     polyA_site      2086
                     /gene="Kcnv1"
                     /gene_synonym="2700023A03Rik; vibe"
                     /note="major polyA site"
     regulatory      2964..2969
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kcnv1"
                     /gene_synonym="2700023A03Rik; vibe"
                     /note="hexamer: AATAAA"
     polyA_site      2988
                     /gene="Kcnv1"
                     /gene_synonym="2700023A03Rik; vibe"
     regulatory      4471..4476
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kcnv1"
                     /gene_synonym="2700023A03Rik; vibe"
                     /note="hexamer: AATATA"
     polyA_site      4494
                     /gene="Kcnv1"
                     /gene_synonym="2700023A03Rik; vibe"
                     /note="major polyA site"
ORIGIN      
        1 gtgtatcctg ggttgttccc tgcctggacg ccacacaact gcttgcaggg ttccctccgc
       61 gcgaccactc ctgtgctccc agcctcatcg ctctaccgcg cactcgcagc tccctagcga
      121 caccagccat caagctggtg gaaagagtag gggtgtgcaa gtgggaggct tctccctcgg
      181 gaacctggga gatccctgcc gccagcaggg gccgtggcac cgcctgcgcg gggacccacg
      241 cttccatcca gcgccttccc aacttcccag tgccttcagg ccaaggcggt caggatggat
      301 ctgtcacccc gcaaccggcc gctactggac tcgtcgtcgc tggacagcgg ttctctgacc
      361 tcactggact ccagtgtctt ctgtagcgag ggcgaagggg aacccttggc tctgggggac
      421 tgctttacag tcaacgtggg cggtagccgc ttcgtgctct cgcagcaagc tctgtcctgc
      481 ttcccgcaca cgcgcctggg caaactggcc gtagtggtgg cctcctaccg ccgcctgggt
      541 gccctggctg ccgcccccag ccccctggag ctttgcgatg atgcgaatcc ggtggacaac
      601 gagtacttct ttgatcgcag ctctcaggcg ttccgttatg tcctgcacta ctatcgcact
      661 ggtcgcctgc atgtcatgga gcagctctgt gcgctctcct ttcttcagga gatccagtac
      721 tggggcatag atgaactcag cattgactcc tgctgcaggg acagatactt cagaagaaag
      781 gagctgagtg aaactcttga ctttaagaag gacacagatg accaggaaag tcaacatgag
      841 agtgaacagg acttctcaaa aggaccttgt cccactgtcc gacaaaagct ctgggatatt
      901 ctggagaaac ctggatcttc cacagcagcc cggatctttg gagtaatctc catcattttt
      961 gtggcagtgt ccatcgtcaa catggccctg atgtcagctg agcttagctg gctcaaccta
     1021 cagctgctgg agatcttgga gtatgtgtgc atcagctggt tcaccgggga gttcgttctg
     1081 cgcttcctat gtgtgaaaga caggtgccac ttcctgagga aggttccaaa catcatagac
     1141 ctccttgcca tcttgccctt ctatataact cttctggtgg aaagcctgag cggcagccac
     1201 accacacaag agctggaaaa tgtgggacgt ctggtccagg tcttgaggct cctcagagct
     1261 ctgcgcatgc tgaaactggg aaggcattct acaggattgc gctcacttgg gatgacaatc
     1321 actcagtgct atgaagaagt tggcctactg ctcctgtttc tatctgtggg gatttctata
     1381 ttttcaacaa tagaatactt tgcagagcaa agcattcctg atacaacctt cacaagtgtt
     1441 ccttgtgcat ggtggtgggc cacaacatcc atgactacag taggatatgg ggacattaga
     1501 ccagacacca ccacaggcaa aatcgtggcc ttcatgtgta ttctgtcagg aatccttgtc
     1561 ttggccttgc ctattgccat tattaatgat cgattctctg cttgctactt caccttgaaa
     1621 ctcaaggaag cagctgtgag acagcgtgaa gctctcaaga aacttaccaa gaatatagcc
     1681 actgactcat atattagtgt taacttgagg gatgtctatg cccggagcat aatggagatg
     1741 cttcgattaa agggcaggga gagagcaagt actagaagca gtggtggaga tgatttctgg
     1801 ttttaagttt accttcaact tatttacaaa acctctgtat atttagctgg attgatgaag
     1861 ccttgctgct atggatatct gtatattgat gatgactttc ttgagcactt ctcatcttct
     1921 ttctggtgta ttgatatcct agaatattta acatctccta tagcaactac tgattatttt
     1981 gacacacatc tttaacatag ccaattaata caaccaaaat caattgggaa aggaaacaca
     2041 tatttgaatt ttcaaatatc aattaatata atttcataca tcaaaattta aagattcatg
     2101 tgtctttatt gttgggcttt cagtagcgct atagtttctg tttttaatgg aagtcgaatt
     2161 ctacagtcca gaggggtggg agaataactg aacatttaaa aacacactga agaaattttt
     2221 gccatttaaa gatttttctc caaataagtt atttctttct ctatcaagta aagccactga
     2281 gtataaagat aagctttgca atcaaacact taagcttagt agccgtagtg agtacctcat
     2341 cttcgatcaa gtacaagtca ctgggtccaa ctggaccgag ctctgccctc catcagttca
     2401 gttgcgagag gaagcctcaa actgaagagt ggagtaggtg agacttcaag tgcctaggca
     2461 gcttcatctt cccagctgag tgtgatgtgt gaagaagaat gcagcatagc tctctaggaa
     2521 aattaaatga tttataaaac atctcattat agatgaatta tttaagctat gctttcaaaa
     2581 tcatgaatat gtaaaactga agtagtaaag atcctaaatt tatccatcaa aaagattaga
     2641 tagtcttttc ataagtggaa atatgttgga tgacatcatt agatgaactt gtagatcttt
     2701 ttatttgtta aaaacaatat tgtgagaagc tttctgactg ttgaggtaaa taacaaatgt
     2761 ttagatgtca ccatcacttc tttggtattt atagtaatac tacaatgcct agacattgtg
     2821 aaatataatt aaaccaaaaa gttttaaagt taagaaaaac cctggttcta aatattatac
     2881 aaagtaatat tttgaaaagc ttaacaaagg atttccttat tgcctacttt cttgatatat
     2941 gcaataaagt tccttaaaaa ataaataaaa ttggctctgg gatagaaatg ttactctccc
     3001 tatttattaa agcaaataca catgaaatgc atatgcatac atgcagaata actgcaatat
     3061 caaaacttcg ctgagaatag aattaggaaa aacacttaga tggtaataag cattgaataa
     3121 cagtttcctt ttaatcctgt aatgcaagcc ccaaatcaca acacatggaa agctaaacca
     3181 gaagacacat aaacctgtag ccaattggac tgcatagcac attctaggtc aggttcatct
     3241 gaagtgcaag ttcaagaaca catcaaggaa tggtaagacc ctgtctcaaa aagtaaaaac
     3301 aataatcctt tgtcttaaca tatggcttta taatttttag tgttctgttt aatgtgtgcc
     3361 tatatatttc accaactgta tttaaggcat cttactatct tacaaactac caagcagcaa
     3421 taaaggtgcc aatcattgtt atgacatcat agattctaag tacattccta atttagatat
     3481 gtaaaatcat aatatttacc acagaaacaa ggtaacacct cctcttttct tatatgcatg
     3541 cttaaaatct gatgaaattt ccatggcatg agttttttta gtataatttt tctactttaa
     3601 ttgtgaatca gaatacatca tgcattctga ttatggtttc acttctctca actcctatga
     3661 gatctttccc atatcccctc acatcaaaat ccacaccttt tcttccctcc cttagaaaac
     3721 acagacatct aaataataaa aataattata aataataata atataaagta ggatttagaa
     3781 caacagaaaa agaagaaaag agggggaaag cacgggaaac actcatagaa aaggcacaca
     3841 cacttgcaca caaaggaatc caataaaaac acataaattg atgccatgat agatacacaa
     3901 agtacctgta aggctacaat aaataaaaat aaataaaaaa atacttcaca agatattatg
     3961 tgacaaagaa cctcaaaaga tgcctctaag tttgttttgt cttggctatc tactgcttat
     4021 gattgggttt tcattcctgg taggagacaa tgaatggaga aaactgattt ttcatttatg
     4081 agttgttata aactggagat aacttccagg ttagagaaag gggctgtgtt aaattctcct
     4141 cttgtctctg ggagtccatc tggtgcagaa ccaggcaaaa ctctgtgtac actgccacag
     4201 tttctatgtt ttcatttgtg cattgatctt gttgtgctta gagggctttg gaccccctat
     4261 tccctctgat tcttacaatc tccctgactc tttttccaca ggattttgta agtctggaag
     4321 aaagaggtat gatggagaca atccatttag gactgagtgt atcaaagtct cttgcactat
     4381 gaacattgtc tagctgtatc tttgtatttg tttcaatgta ctacaaaaag gtatttctct
     4441 gatgatgact gaacaaggca caaaattgtg aatatagcaa gatgttatta gaaatc
//
