LOCUS       NM_001195074             720 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus potassium large conductance calcium-activated channel,
            subfamily M, beta member 3 (Kcnmb3), mRNA.
ACCESSION   NM_001195074 XM_001475546
VERSION     NM_001195074.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Hayashi Y, Morinaga S, Zhang J, Satoh Y, Meredith AL, Nakata T, Wu
            Z, Kohsaka S, Inoue K and Nakanishi H.
  TITLE     BK channels in microglia are required for morphine-induced
            hyperalgesia
  JOURNAL   Nat Commun 7, 11697 (2016)
   PUBMED   27241733
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC130281.13.
            
            On Aug 19, 2010 this sequence version replaced XM_001475546.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR4095033.859.1, SRR4048179.9084.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849388
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-62                AC130281.13        127320-127381
            63-236              AC130281.13        136774-136947
            237-435             AC130281.13        145412-145610
            436-720             AC130281.13        146684-146968
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 15.73 cM"
     gene            1..720
                     /gene="Kcnmb3"
                     /gene_synonym="EG435726; Gm5707"
                     /note="potassium large conductance calcium-activated
                     channel, subfamily M, beta member 3"
                     /db_xref="GeneID:100502876"
                     /db_xref="MGI:MGI:3612244"
     CDS             1..720
                     /gene="Kcnmb3"
                     /gene_synonym="EG435726; Gm5707"
                     /note="potassium large conductance calcium-activated
                     channel, subfamily M, beta member 4"
                     /codon_start=1
                     /product="calcium-activated potassium channel subunit
                     beta-3"
                     /protein_id="NP_001182003.1"
                     /db_xref="CCDS:CCDS57206.1"
                     /db_xref="GeneID:100502876"
                     /db_xref="MGI:MGI:3612244"
                     /translation="MQPFSIPVQITLQGGRRRQGRTALPASGKINGDPLKVHPKLPSS
                     AGEDRAMLLGVAMMASSVLMFFLLGTTVLKPFMLRSPREESNCTTVHTHIVDDGLDFS
                     FTCEGSCQDHGRSPCLQVFVNLSHSGQKVLLHYDDEAIRTNPKCFYTPKCHGDRDDLL
                     NSVLDIKEFFDHNNGTFPCFYSPDGPLGVVLRKSGHKVVFHCLFWPLLTLLGGALIVG
                     LVRLTQHLSFQCEQYSTVVRA"
     exon            1..62
                     /gene="Kcnmb3"
                     /gene_synonym="EG435726; Gm5707"
                     /inference="alignment:Splign:2.1.0"
     exon            63..236
                     /gene="Kcnmb3"
                     /gene_synonym="EG435726; Gm5707"
                     /inference="alignment:Splign:2.1.0"
     exon            237..435
                     /gene="Kcnmb3"
                     /gene_synonym="EG435726; Gm5707"
                     /inference="alignment:Splign:2.1.0"
     exon            436..720
                     /gene="Kcnmb3"
                     /gene_synonym="EG435726; Gm5707"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgcagccct tcagcatccc tgtccaaatc acgctacagg gtggccggag gcgccaaggg
       61 aggacagcac ttccggcctc gggcaaaatc aatggagatc ccctgaaggt gcacccaaag
      121 cttccatcaa gcgctggtga ggaccgggcc atgctgctgg gcgtggccat gatggcttcc
      181 tctgtactga tgttcttcct gttggggacc actgtgttga agcccttcat gctcagatct
      241 cccagagaag aatcaaactg caccactgtc cacacacaca ttgtggatga cgggctggac
      301 ttttccttca cctgtgaggg tagctgccag gaccacggga gatccccatg cctgcaggtg
      361 ttcgtaaacc tgagccactc gggacagaaa gtgcttctcc actacgacga cgaggccatc
      421 aggaccaacc ccaagtgctt ttacacaccc aagtgtcacg gagaccggga tgatctgctc
      481 aacagcgtcc tggacatcaa ggaattcttc gatcacaaca atggaacttt cccctgtttc
      541 tacagtcccg atggcccctt gggagttgtt ctgaggaagt ctggccacaa ggttgtcttt
      601 cactgcttat tttggccttt attgactttg ctgggaggcg ccctgattgt tggcttggtt
      661 aggctaacac aacatctgtc ctttcagtgt gaacagtaca gcacagtggt aagagcttaa
//
