LOCUS       NM_133207               3798 bp    mRNA    linear   ROD 20-OCT-2024
DEFINITION  Mus musculus potassium voltage-gated channel, subfamily H
            (eag-related), member 7 (Kcnh7), mRNA.
ACCESSION   NM_133207 NM_178805
VERSION     NM_133207.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3798)
  AUTHORS   Schwarz,J.R., Freitag,S., Pechmann,Y., Hermans-Borgmeyer,I.,
            Wagner,W., Hornig,S. and Kneussel,M.
  TITLE     Purkinje cell hyperexcitability and depressive-like behavior in
            mice lacking erg3 (ether-a-go-go-related gene) K+ channel subunits
  JOURNAL   Sci Adv 10 (40), eadn6836 (2024)
   PUBMED   39365861
  REMARK    GeneRIF: Purkinje cell hyperexcitability and depressive-like
            behavior in mice lacking erg3 (ether-a-go-go-related gene) K[+]
            channel subunits.
REFERENCE   2  (bases 1 to 3798)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 3798)
  AUTHORS   Alderman,P.J., Saxon,D., Torrijos-Saiz,L.I., Sharief,M., Page,C.E.,
            Baroudi,J.K., Biagiotti,S.W., Butyrkin,V.A., Melamed,A., Kuo,C.T.,
            Vicini,S., Garcia-Verdugo,J.M., Herranz-Perez,V., Corbin,J.G. and
            Sorrells,S.F.
  TITLE     Delayed maturation and migration of excitatory neurons in the
            juvenile mouse paralaminar amygdala
  JOURNAL   Neuron 112 (4), 574-592 (2024)
   PUBMED   38086370
REFERENCE   4  (bases 1 to 3798)
  AUTHORS   Ding,Y., Lang,D., Yan,J., Bu,H., Li,H., Jiao,K., Yang,J., Ni,H.,
            Morotti,S., Le,T., Clark,K.J., Port,J., Ekker,S.C., Cao,H.,
            Zhang,Y., Wang,J., Grandi,E., Li,Z., Shi,Y., Li,Y., Glukhov,A.V.
            and Xu,X.
  TITLE     A phenotype-based forward genetic screen identifies Dnajb6 as a
            sick sinus syndrome gene
  JOURNAL   Elife 11, e77327 (2022)
   PUBMED   36255053
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3798)
  AUTHORS   Ye,Q., Bhojwani,A. and Hu,J.K.
  TITLE     Understanding the development of oral epithelial organs through
            single cell transcriptomic analysis
  JOURNAL   Development 149 (16) (2022)
   PUBMED   35831953
REFERENCE   6  (bases 1 to 3798)
  AUTHORS   Nakano,Y., Jahan,I., Bonde,G., Sun,X., Hildebrand,M.S.,
            Engelhardt,J.F., Smith,R.J., Cornell,R.A., Fritzsch,B. and Banfi,B.
  TITLE     A mutation in the Srrm4 gene causes alternative splicing defects
            and deafness in the Bronx waltzer mouse
  JOURNAL   PLoS Genet 8 (10), e1002966 (2012)
   PUBMED   23055939
REFERENCE   7  (bases 1 to 3798)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   8  (bases 1 to 3798)
  AUTHORS   Hardman,R.M. and Forsythe,I.D.
  TITLE     Ether-a-go-go-related gene K+ channels contribute to threshold
            excitability of mouse auditory brainstem neurons
  JOURNAL   J Physiol 587 (Pt 11), 2487-2497 (2009)
   PUBMED   19359372
  REMARK    GeneRIF: ERG3 K+ channels contribute to threshold excitability of
            mouse auditory brainstem neurons.
REFERENCE   9  (bases 1 to 3798)
  AUTHORS   Harrell,M.D., Harbi,S., Hoffman,J.F., Zavadil,J. and Coetzee,W.A.
  TITLE     Large-scale analysis of ion channel gene expression in the mouse
            heart during perinatal development
  JOURNAL   Physiol Genomics 28 (3), 273-283 (2007)
   PUBMED   16985003
REFERENCE   10 (bases 1 to 3798)
  AUTHORS   Polvani,S., Masi,A., Pillozzi,S., Gragnani,L., Crociani,O.,
            Olivotto,M., Becchetti,A., Wanke,E. and Arcangeli,A.
  TITLE     Developmentally regulated expression of the mouse homologues of the
            potassium channel encoding genes m-erg1, m-erg2 and m-erg3
  JOURNAL   Gene Expr Patterns 3 (6), 767-776 (2003)
   PUBMED   14643686
  REMARK    GeneRIF: erg3 gene expression pattern in the developing embryo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928663.4, AL928689.7 and AL929246.7.
            
            On Oct 31, 2006 this sequence version replaced NM_133207.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ291608.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849383,
                                           SAMN00849384 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-286               AL928663.4         67652-67937         c
            287-517             AL928663.4         65706-65936         c
            518-673             AL928689.7         157948-158103       c
            674-1102            AL928689.7         131096-131524       c
            1103-1123           AL928689.7         126500-126520       c
            1124-1338           AL928689.7         117812-118026       c
            1339-1764           AL928689.7         68336-68761         c
            1765-2164           AL928689.7         58028-58427         c
            2165-2364           AL928689.7         45317-45516         c
            2365-2617           AL928689.7         19890-20142         c
            2618-2823           AL928689.7         16719-16924         c
            2824-2905           AL928689.7         14965-15046         c
            2906-3169           AL928689.7         2433-2696           c
            3170-3338           AL929246.7         137759-137927       c
            3339-3531           AL929246.7         127567-127759       c
            3532-3798           AL929246.7         124597-124863       c
FEATURES             Location/Qualifiers
     source          1..3798
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 36.5 cM"
     gene            1..3798
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /note="potassium voltage-gated channel, subfamily H
                     (eag-related), member 7"
                     /db_xref="GeneID:170738"
                     /db_xref="MGI:MGI:2159566"
     exon            1..286
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            287..517
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            518..673
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            674..1102
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1103..1123
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1124..1338
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1339..1764
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..2164
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            2165..2364
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            2365..2617
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            2618..2823
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            2824..2905
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            2906..3169
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            3170..3338
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            3339..3531
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
     exon            3532..3798
                     /gene="Kcnh7"
                     /gene_synonym="9330137I11Rik; erg3; Kv11.3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgaggcccc ctccggaagg tgagcgggat ggattggact tcggcggaga acgcgggtgt
       61 ctcgaagtgg tgctaatggg aagagatttc tgctccccaa agaagatgcg ctgccacaaa
      121 gagcggcttg cgcgccggcc tgggctctag cccgggagac atcccgggag aactctgagc
      181 tcggagcgct cggcgaagac ccggggcaac atgcctgttc gcagggggca tgtggcaccg
      241 caaaacacct tcctggggac catcatacgg aaatttgaag ggcagaataa aaaatttatc
      301 attgcaaatg ccagagtgca gaactgtgct atcatctact gcaatgatgg cttctgtgag
      361 atgacgggtt tctccaggcc agatgtcatg cagaagccgt gtacctgtga ctttctccat
      421 gggcctgaga ccaagaggca tgatattgcc cagattgccc aggcgctgct ggggtcagag
      481 gagaggaaag tggaggtcac ctactatcac aagaatggtt ccacttttat ttgtaacact
      541 cacataatcc cagtaaagaa ccaagagggt gtggctatga tgttcatcat taattttgag
      601 tatgtgacag atgaagaaaa tgctgccact ccagagaggg tcaacccgat attaccagtc
      661 aagactgtaa accggaaact ttttgggttc aaatttcctg gactgagagt tctaacatac
      721 agaaaacagt ccttgccaca ggaagacccg gatgtggtag ttattgattc ttctaaacac
      781 agcgatgact ctgtggccat gaagcacttt aagtctccca cgaaagaaag ttgcagtccc
      841 tctgaagcag atgatacgaa agccttgata cagcctagcc agtgttctcc cttagtgaac
      901 atatcaggac ctctggacca ttcctctccc aaaagacaat gggaccgcct ctaccctgac
      961 atgctgcagt caagttccca actaacacac tccaggtcaa gggagagcct ctgtagcata
     1021 cggagggcat cttcagttca tgatatagaa gggttcagtg tccaccccaa gaacatattt
     1081 agagatcgac atgccagtga agacaatggt cgaaatgtca aaggaccttt taatcatatc
     1141 aagtcaagcc tgctgggatc cacatcagat tcaaacctca ataagtacag caccattaac
     1201 aagatcccac aactcactct gaatttctca gatgtcaaaa cagaaaagaa gaatacatcc
     1261 cctccttctt cagacaaaac tattattgca cccaaggtta aagaaaggac acacaacgtg
     1321 accgagaaag taacccaggt tctttctttg ggagcagatg tcttgccaga atataagctg
     1381 cagacgccac gcatcaacaa atttacaata ttgcactaca gtcctttcaa agcagtctgg
     1441 gattggctta ttttactctt ggtcatttat actgctatat tcacccccta ctctgcagca
     1501 tttctcctca atgacagaga ggaacagaaa aggcgagaat gtggctattc ttgtagccct
     1561 ttgaatgtgg tagacttgat tgtggatatt atgtttatta tagacattct aataaacttc
     1621 agaacaacct atgtaaatca gaatgaagaa gtggtaagtg atcctgccaa aatagcaata
     1681 cactacttca aaggctggtt cctgattgac atggttgcag ccattccttt tgacttgctg
     1741 atttttggat caggttctga tgagacaacg acactaattg gtcttttgaa gactgcacga
     1801 ctcctgcgtc ttgtgcgcgt agccaggaaa ctggaccgat actcagaata tggtgcggct
     1861 gttctaatgc tcttgatgtg catatttgcc ctgattgccc actggctggc ttgcatctgg
     1921 tatgcgattg ggaatgtaga gaggccctat ctgactgaca aaattggatg gttggattcc
     1981 ttaggaacac aaattgggaa acgttacaat gacagtgact cgagttctgg accgtccatt
     2041 aaagacaaat acgtcacggc actttatttt accttcagca gtctaaccag tgtaggattt
     2101 ggaaatgtgt ctcctaacac caattcggag aaaatctttt ccatttgtgt catgttgatt
     2161 ggctctctaa tgtatgcgag catttttggg aacgtttctg caattattca aagactgtac
     2221 tcaggaactg ccaggtacca catgcagatg ctgagagtaa aagagttcat tcgcttccac
     2281 caaatcccca accctttgag gcaacggctt gaggagtatt tccagcatgc atggacttac
     2341 actaacggca tagacatgaa catggtctta aagggatttc cagaatgttt acaagctgac
     2401 atttgcctgc atctgaacca gactttgcta caaaactgca aagcctttcg aggagcaagt
     2461 aaaggctgtc ttagagctct ggcaatgaag ttcaaaacca cccatgcccc tccaggagac
     2521 accctggttc actgtgggga tgttctaact gcactgtact tcttatccag aggctccatt
     2581 gaaatcctca aggatgatat agtggtagct attcttggaa aaaatgatat ctttggggaa
     2641 atggttcatc tttatgccaa acctggcaag tctaatgcag atgtgagagc acttacgtac
     2701 tgtgacctgc ataagattca gcgagaagat ttattagagg tcttggatat gtatccagaa
     2761 ttttctgatc actttctgac aaatctagaa ctgactttca acctgagaca tgaaagtgcc
     2821 aagtcccaat ctgtaaatga ttctgaagga gacaccggta aacttcggag aaggcgattg
     2881 tcctttgaaa gtgaagggga aaaagatttt agcaaagaaa acagtgcaaa tgacgctgac
     2941 gactctacag atacaataag gcgttaccag agttccaaga agcacttcga agagaggaaa
     3001 agcagatcgt catcgttcat ctcctccatt gatgatgagc aaaagccact cttcttagga
     3061 acagtagatt ctactccaag aatggtgaaa gcaaccagac tccatggtga agaaacaatg
     3121 ccacactcag gaagaattca cacagaaaaa aggagtcact cctgcagaga tatcactgat
     3181 acacacagct gggaaagaga gcctgcccgg gctcaacctg aagaatgtag tccctcagga
     3241 cttcagagag ctgcctgggg cgtctctgag acggaaagcg acctcaccta tggggaagtg
     3301 gagcaaagat tagatttact tcaagagcaa cttaacagac ttgaatccca aatgacaacg
     3361 gacatccagg ccatcttgca gctcctgcag aaacaaacca cggtagtccc tccagcctac
     3421 agcatggtga ctgcaggagc agagtaccag aggcccatcc tccgtctgtt gagaaccagt
     3481 caccccagag catccattaa gactgaccgg agtttcagcc cctcctcaca gtgtcctgaa
     3541 tttctcgacc tcgaaaaatc caaactccaa tccaaagagt cactctcaag cggaaggcgc
     3601 ctgaacacag cttccgaaga caacttgact tcccttttaa aacaagacag tgatgcgtca
     3661 tcagagcttg accctcggca aaggaaaact taccttcatc ccatccggca tccctctctg
     3721 ccagactcct ccctaagcac tgtagggatc ttgggtctcc ataggcatgt ctctgaccct
     3781 ggtcttccag ggaagtaa
//
