LOCUS       NM_010601               3967 bp    mRNA    linear   ROD 08-FEB-2025
DEFINITION  Mus musculus potassium voltage-gated channel, subfamily H
            (eag-related), member 3 (Kcnh3), mRNA.
ACCESSION   NM_010601
VERSION     NM_010601.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3967)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3967)
  AUTHORS   Hermanstyne,T.O., Yang,N.D., Granados-Fuentes,D., Li,X.,
            Mellor,R.L., Jegla,T., Herzog,E.D. and Nerbonne,J.M.
  TITLE     Kv12-encoded K+ channels drive the day-night switch in the
            repetitive firing rates of SCN neurons
  JOURNAL   J Gen Physiol 155 (9) (2023)
   PUBMED   37516908
  REMARK    GeneRIF: Kv12-encoded K+ channels drive the day-night switch in the
            repetitive firing rates of SCN neurons.
REFERENCE   3  (bases 1 to 3967)
  AUTHORS   Sundberg,J.P., Dadras,S.S., Silva,K.A., Kennedy,V.E., Garland,G.,
            Murray,S.A., Sundberg,B.A., Schofield,P.N. and Pratt,C.H.
  TITLE     Systematic screening for skin, hair, and nail abnormalities in a
            large-scale knockout mouse program
  JOURNAL   PLoS One 12 (7), e0180682 (2017)
   PUBMED   28700664
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3967)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   5  (bases 1 to 3967)
  AUTHORS   Vezzali,R., Weise,S.C., Hellbach,N., Machado,V., Heidrich,S. and
            Vogel,T.
  TITLE     The FOXG1/FOXO/SMAD network balances proliferation and
            differentiation of cortical progenitors and activates Kcnh3
            expression in mature neurons
  JOURNAL   Oncotarget 7 (25), 37436-37455 (2016)
   PUBMED   27224923
  REMARK    GeneRIF: Authors identified ligands of the TGFbeta- and IGF-family,
            Foxo1, Foxo3 and Kcnh3 as novel FOXG1-target genes during
            telencephalic development and showed that FOXG1 interferes with
            Foxo1 and Tgfbeta transcription.
REFERENCE   6  (bases 1 to 3967)
  AUTHORS   Noma,K., Kimura,K., Minatohara,K., Nakashima,H., Nagao,Y.,
            Mizoguchi,A. and Fujiyoshi,Y.
  TITLE     Triple N-glycosylation in the long S5-P loop regulates the
            activation and trafficking of the Kv12.2 potassium channel
  JOURNAL   J Biol Chem 284 (48), 33139-33150 (2009)
   PUBMED   19808681
  REMARK    GeneRIF: Data suggest that only glycosylated Kv12.2 channels
            (Kcnh3) show proper voltage dependence and are utilized in vivo.
REFERENCE   7  (bases 1 to 3967)
  AUTHORS   Miyake,A., Takahashi,S., Nakamura,Y., Inamura,K., Matsumoto,S.,
            Mochizuki,S. and Katou,M.
  TITLE     Disruption of the ether-a-go-go K+ channel gene BEC1/KCNH3 enhances
            cognitive function
  JOURNAL   J Neurosci 29 (46), 14637-14645 (2009)
   PUBMED   19923296
REFERENCE   8  (bases 1 to 3967)
  AUTHORS   Clancy,S.M., Chen,B., Bertaso,F., Mamet,J. and Jegla,T.
  TITLE     KCNE1 and KCNE3 beta-subunits regulate membrane surface expression
            of Kv12.2 K(+) channels in vitro and form a tripartite complex in
            vivo
  JOURNAL   PLoS One 4 (7), e6330 (2009)
   PUBMED   19623261
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 3967)
  AUTHORS   Harrell,M.D., Harbi,S., Hoffman,J.F., Zavadil,J. and Coetzee,W.A.
  TITLE     Large-scale analysis of ion channel gene expression in the mouse
            heart during perinatal development
  JOURNAL   Physiol Genomics 28 (3), 273-283 (2007)
   PUBMED   16985003
REFERENCE   10 (bases 1 to 3967)
  AUTHORS   Trudeau,M.C., Titus,S.A., Branchaw,J.L., Ganetzky,B. and
            Robertson,G.A.
  TITLE     Functional analysis of a mouse brain Elk-type K+ channel
  JOURNAL   J Neurosci 19 (8), 2906-2918 (1999)
   PUBMED   10191308
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC161198.5.
            
            On Jun 20, 2019 this sequence version replaced NM_010601.3.
            
            Summary: The protein encoded by this gene is a voltage-gated
            potassium channel alpha subunit predominantly expressed in the
            forebrain. An increase in cognitive function was observed when this
            gene was knocked out, while deletion of the gene resulted in
            hippocampal hyperexcitability and epilepsy. [provided by RefSeq,
            Sep 2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC141013.1, AY380579.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-460               AC161198.5         136739-137198
            461-694             AC161198.5         138455-138688
            695-829             AC161198.5         139128-139262
            830-963             AC161198.5         140056-140189
            964-1207            AC161198.5         140620-140863
            1208-1365           AC161198.5         141206-141363
            1366-1573           AC161198.5         141453-141660
            1574-1885           AC161198.5         144840-145151
            1886-2085           AC161198.5         145396-145595
            2086-2335           AC161198.5         146014-146263
            2336-2553           AC161198.5         150222-150439
            2554-2885           AC161198.5         151742-152073
            2886-2992           AC161198.5         153034-153140
            2993-3069           AC161198.5         153897-153973
            3070-3967           AC161198.5         154067-154964
FEATURES             Location/Qualifiers
     source          1..3967
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 56.08 cM"
     gene            1..3967
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /note="potassium voltage-gated channel, subfamily H
                     (eag-related), member 3"
                     /db_xref="GeneID:16512"
                     /db_xref="MGI:MGI:1341723"
     exon            1..460
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     CDS             385..3672
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /note="potassium voltage-gated channel subfamily H member
                     3; ELK channel 2; ether-a-go-go-like potassium channel 2;
                     voltage-gated potassium channel subunit Kv12.2; ether a
                     go-go like"
                     /codon_start=1
                     /product="voltage-gated inwardly rectifying potassium
                     channel KCNH3"
                     /protein_id="NP_034731.3"
                     /db_xref="CCDS:CCDS27817.1"
                     /db_xref="GeneID:16512"
                     /db_xref="MGI:MGI:1341723"
                     /translation="MPAMRGLLAPQNTFLDTIATRFDGTHSNFVLGNAQVAGLFPVVY
                     CSDGFCDLTGFSRAEVMQRGCACSFLYGPDTSELVRQQIRKALDEHKEFKAELILYRK
                     SGLPFWCLLDVIPIKNEKGEVALFLVSHKDISETKNRGGPDNWKERGGGRRRYGRAGS
                     KGFNANRRRSRAVLYHLSGHLQKQPKGKHKLNKGVFGEKPNLPEYKVAAIRKSPFILL
                     HCGALRATWDGFILLATLYVAVTVPYSVCVSTAREPSAARGPPSVCDLAVEVLFILDI
                     VLNFRTTFVSKSGQVVFAPKSICLHYVTTWFLLDVIAALPFDLLHAFKVNVYVGAHLL
                     KTVRLLRLLRLLPRLDRYSQYSAVVLTLLMAVFALLAHWVACVWFYIGQQEIESSESE
                     LPEIGWLQELARRLETPYYLVSRSPDGGNSSGQSENCSSSSSSSGSGGGRGSEANGTG
                     LELLGGPSLRSAYITSLYFALSSLTSVGFGNVSANTDTEKIFSICTMLIGALMHAVVF
                     GNVTAIIQRMYARRFLYHSRTRDLRDYIRIHRIPKPLKQRMLEYFQATWAVNNGIDTT
                     ELLQSLPDELRADIAMHLHKEVLQLPLFEAASRGCLRALSLALRPAFCTPGEYLIHQG
                     DALQALYFVCSGSMEVLKGGTVLAILGKGDLIGCELPQREQVVKANADVKGLTYCVLQ
                     CLQLAGLHESLALYPEFAPRFSRGLRGELSYNLGAGGVSAEVDTSSLSGDNTLMSTLE
                     EKETDGEQGHTVSPAPADEPSSPLLSPGCTSSSSAAKLLSPRRTAPRPRLGGRGRPSR
                     AGVLKPEAGPSAHPRSLDGLQLPPMPWNVPPDLSPRVVDGIEDGCSSDQPKFSFRVGQ
                     SGPECSSSPSPGTESGLLTVPLGPSEARNTDTLDKLRQAVMELSEQVLQMREGLQSLR
                     QAVQLILVPQGEGQCPRGSGEEPCPATASGLLQPLRVDTGASSYCLQPPAGSVLSGTW
                     PHPRPGQPPPLMAPWPWGPPASQSSPWPRATALWTSTSDSEPPGSGDLCSEPSTPASP
                     PPSEEGARTGTPAPVSQAEATSTGEPPPGPGGRALPWDPHSLEMVLIGCHGPGTVQWT
                     QEEGTGV"
     exon            461..694
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     exon            695..829
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     exon            830..963
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1207
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..1365
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1573
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     exon            1574..1885
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     exon            1886..2085
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     exon            2086..2335
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     exon            2336..2553
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     exon            2554..2885
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     exon            2886..2992
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     exon            2993..3069
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     exon            3070..3967
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3955..3960
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /note="hexamer: AATAAA"
     polyA_site      3961
                     /gene="Kcnh3"
                     /gene_synonym="C030044P22Rik; Elk2; Kv12.2; Melk2"
                     /note="major polyA site"
ORIGIN      
        1 aggctgccgc ttctccccga cagacggagg gagctgcggg gacccggcgc tgagccgagc
       61 ccaagcggga gccaccccgc ttgcagaaac aggagccgcg ggcggaccaa aggtgcagag
      121 tgcgcggtgg ccgcggggcc tgcagcccgg aatccgtggg cggcgagggg tcgcgcgcgc
      181 gccatgcgcc cagccccgac ggtgcggacg cccccttgtg cgccggcagc tgctggggcc
      241 tgcgagcctg ggccgggcat agccccccga cggctactct agggggcgcg gggcccggcg
      301 gggggcggcc gagccaggcg ccctcccccg gcgctgagtc cccgcgcccc ggagggatgg
      361 ggcgggcggc ccccgccgcc taagatgccg gccatgcggg ggctcctggc gccgcagaac
      421 accttcctgg acaccatcgc cacccgcttc gacgggacgc acagcaactt cgtgctgggc
      481 aacgcccagg tggcggggct cttccctgtg gtctactgct ccgatggctt ctgtgacctc
      541 acgggtttct ccagagctga ggtcatgcag cggggctgtg cctgctcctt cctctatggg
      601 ccagacacca gtgagctggt ccgccaacag atccgaaagg ccctagatga gcacaaagaa
      661 ttcaaggctg aactgatcct gtaccggaag agtgggcttc cattctggtg tctcctggat
      721 gtgataccta taaaaaatga gaagggggag gtggccctct tcctggtctc tcacaaggac
      781 atcagcgaga ccaagaaccg aggaggccct gacaactgga aggagagagg cggtggccgg
      841 cgccgatatg gtcgggccgg atccaaaggc ttcaatgcca atcggaggcg gagccgggca
      901 gttctctacc acctctctgg ccatctgcag aagcaaccca agggcaagca caagctcaat
      961 aagggagtgt ttggagagaa gccaaatttg cctgaatata aagtcgctgc tatccggaag
     1021 tcacccttta tcctgctgca ctgtggggct ctgagagcca cctgggatgg cttcatcctg
     1081 cttgccacac tctacgtggc agtcactgtg ccatacagtg tgtgtgtgag cacagcacgg
     1141 gaacccagtg ctgcccgtgg cccacctagt gtctgtgacc tggctgtgga ggtcctcttc
     1201 atcttagata ttgtgctgaa ttttcgtact acatttgtgt ccaagtcagg ccaggtggta
     1261 tttgccccaa agtccatttg cctccactac gtcaccacct ggttcctgct ggatgtcata
     1321 gcagcactgc cctttgacct actacatgcc ttcaaggtca acgtgtacgt tggggctcac
     1381 ctcctgaaga ccgtgcgact gctgcgcctg ctgcgcctgc tgccaagact ggaccggtac
     1441 tcacagtaca gcgcggttgt gctcaccttg ctcatggctg tcttcgccct gctcgctcac
     1501 tgggtggcct gcgtctggtt ttacatcggc cagcaagaga ttgagagcag cgagtcggag
     1561 ctgcctgaga tcggctggct gcaggagctg gcacgcaggc tggagacccc ctactacctg
     1621 gtgagccgga gtccagatgg agggaacagc tctggccaga gtgaaaactg cagcagcagc
     1681 agcagcagca gtggcagcgg tggcggcaga ggcagcgaag ccaatgggac cgggctggag
     1741 ctgctgggtg gcccgtccct acgcagcgcc tacatcacct ccctgtactt cgcgctcagc
     1801 agtctcacca gtgtgggctt cggcaacgtg tccgctaaca cagacacgga gaagatcttc
     1861 tccatctgca ccatgcttat cggagctcta atgcatgcag tggtgtttgg gaatgtgacg
     1921 gccatcatcc agcgcatgta tgctcgccgc tttctgtacc acagccgcac tcgtgacctg
     1981 cgagactaca tccgcatcca ccgcatcccc aaacccctca aacaacgaat gctggagtac
     2041 ttccaagcca cctgggctgt gaacaatggc atcgatacca ctgagctgct gcagagcctc
     2101 ccggatgagc ttcgtgcaga catcgccatg cacctgcaca aggaagtcct gcagctgccg
     2161 ctgttcgagg ccgccagccg tggctgcctg cgggcgctgt ccctggccct gaggccggcc
     2221 ttctgcacgc cgggcgagta cctcattcac caaggcgatg ctctccaggc cctctatttt
     2281 gtctgctcgg gttccatgga ggtcctcaaa ggtggcaccg tgctcgccat tctagggaag
     2341 ggtgacctga tcggctgcga gctgccccag cgggaacaag tagtgaaggc caatgcagac
     2401 gtgaaggggc tgacatactg cgtcctacag tgtctgcagt tggctgggct gcatgagagc
     2461 cttgctctgt accctgagtt tgccccacgc tttagccgtg gcctccgagg ggagctcagc
     2521 tacaacctgg gagctggtgg agtctctgcg gaggtggata ccagctccct gagtggtgac
     2581 aacaccctca tgtccacact ggaggagaag gagacagatg gggagcaggg acacacggtc
     2641 tcaccagccc cagcagatga gccctccagt cccctgctgt cgcccggctg tacctcctcc
     2701 tcctcagccg ccaaactact ctccccacgt cgaactgcgc ctcggccgag gttgggtggc
     2761 agagggcggc caagtagggc aggggttttg aagcctgagg ctggtccttc tgctcatcca
     2821 cggtcacttg atgggctgca gctacccccc atgccatgga atgtaccccc agacctgagc
     2881 cccagggtcg tagatggcat tgaagatggc tgcagctctg accagcccaa gttctctttc
     2941 cgagtgggtc agtctggccc agaatgtagc agcagcccct ccccaggaac agagagcggc
     3001 ctgcttacag tccccttggg gcccagtgaa gcaagaaaca cagacacgct ggacaagcta
     3061 cggcaggcgg tgatggagct gtctgaacag gtgctgcaga tgcgggaggg actgcagtca
     3121 cttcgccagg ctgtgcagct catcctggtg ccccaagggg aaggccagtg tccccgggga
     3181 tcaggagagg agccgtgccc agccaccgcc tctgggctcc tacaacccct gcgtgtggac
     3241 actggggcat cgtcctactg cctgcagccc ccagcaggtt cggttttgag tgggacctgg
     3301 cctcaccccc gtccagggca accccctccc ctcatggcgc cctggccctg gggcccccca
     3361 gcatctcaga gctccccttg gcctcgagcc acagctttat ggacctccac ttcagactcg
     3421 gagccccctg gctctggaga tctctgctct gagcccagca caccagcctc accccctcct
     3481 tctgaggaag gggctaggac tgggacccca gcacctgtga gccaggctga ggctaccagt
     3541 actggagagc cccctccggg gccaggaggc cgagccttgc cctgggatcc ccacagccta
     3601 gagatggtgc tcattggctg ccacggtcct ggcacggtcc agtggaccca ggaagaaggc
     3661 acaggggtct gactgcggct ggagatgagt actacaaaca cctgccacct gctgctccgc
     3721 ctagccacac agggctgctc agggcaggga gcctgaggga ggaggaggct gagctggagc
     3781 ctcaggcagg ccccaggcta gagatccaca ggctctgctc cactgacctg cttgtccacc
     3841 ctctgcctgc cagatggggg cagaggtctg aggacgggga ggggttctgc cattccttgc
     3901 atgtgcccgt ctccactgtc ctcatgtttt ttatattaaa aaacattaaa aaaaaataaa
     3961 agaagct
//
