LOCUS       NM_010595               8970 bp    mRNA    linear   ROD 24-SEP-2024
DEFINITION  Mus musculus potassium voltage-gated channel, shaker-related
            subfamily, member 1 (Kcna1), mRNA.
ACCESSION   NM_010595 XM_987093 XM_987137
VERSION     NM_010595.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8970)
  AUTHORS   Peters,C., Aberle,T., Sock,E., Brunner,J., Kuspert,M.,
            Hillgartner,S., Wust,H.M. and Wegner,M.
  TITLE     Voltage-Gated Ion Channels Are Transcriptional Targets of Sox10
            during Oligodendrocyte Development
  JOURNAL   Cells 13 (13), 1159 (2024)
   PUBMED   38995010
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8970)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 8970)
  AUTHORS   George,A.G., Federico,A., Gom,R.C., Harris,S.A. and Teskey,G.C.
  TITLE     Caffeine exacerbates seizure-induced death via postictal hypoxia
  JOURNAL   Sci Rep 13 (1), 14150 (2023)
   PUBMED   37644198
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8970)
  AUTHORS   Martin,H.G.S. and Kullmann,D.M.
  TITLE     Basket to Purkinje Cell Inhibitory Ephaptic Coupling Is Abolished
            in Episodic Ataxia Type 1
  JOURNAL   Cells 12 (10), 1382 (2023)
   PUBMED   37408217
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 8970)
  AUTHORS   Aloi,M.S., Thompson,S.J., Quartapella,N. and Noebels,J.L.
  TITLE     Loss of functional System x-c uncouples aberrant postnatal
            neurogenesis from epileptogenesis in the hippocampus of Kcna1-KO
            mice
  JOURNAL   Cell Rep 41 (8), 111696 (2022)
   PUBMED   36417872
  REMARK    GeneRIF: Loss of functional System x-c uncouples aberrant postnatal
            neurogenesis from epileptogenesis in the hippocampus of Kcna1-KO
            mice.
REFERENCE   6  (bases 1 to 8970)
  AUTHORS   Lesage,F., Attali,B., Lazdunski,M. and Barhanin,J.
  TITLE     Developmental expression of voltage-sensitive K+ channels in mouse
            skeletal muscle and C2C12 cells
  JOURNAL   FEBS Lett 310 (2), 162-166 (1992)
   PUBMED   1383027
REFERENCE   7  (bases 1 to 8970)
  AUTHORS   Salkoff,L., Baker,K., Butler,A., Covarrubias,M., Pak,M.D. and
            Wei,A.
  TITLE     An essential 'set' of K+ channels conserved in flies, mice and
            humans
  JOURNAL   Trends Neurosci 15 (5), 161-166 (1992)
   PUBMED   1377421
  REMARK    Review article
REFERENCE   8  (bases 1 to 8970)
  AUTHORS   Ferroni,S., Planells-Cases,R., Ahmed,C.M. and Montal,M.
  TITLE     Expression of a genomic clone encoding a brain potassium channel in
            mammalian cells using lipofection
  JOURNAL   Eur Biophys J 21 (3), 185-191 (1992)
   PUBMED   1425474
REFERENCE   9  (bases 1 to 8970)
  AUTHORS   Migeon,M.B., Street,V.A., Demas,V.P. and Tempel,B.L.
  TITLE     Cloning, sequence and chromosomal localization of MK6, a murine
            potassium channel gene
  JOURNAL   Epilepsy Res Suppl 9, 173-80 (1992)
   PUBMED   1285906
REFERENCE   10 (bases 1 to 8970)
  AUTHORS   Klumpp,D.J., Farber,D.B., Bowes,C., Song,E.J. and Pinto,L.H.
  TITLE     The potassium channel MBK1 (Kv1.1) is expressed in the mouse retina
  JOURNAL   Cell Mol Neurobiol 11 (6), 611-622 (1991)
   PUBMED   1723658
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC079438.30.
            
            On Dec 14, 2006 this sequence version replaced NM_010595.2.
            
            Sequence Note: This RefSeq record was created using genomic
            sequence from C57BL/6J because full-length sequence was not
            available from a single strain at the time of review. This
            transcript is supported by human sequences.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK039559.1, BC112970.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1546              AC079438.30        145496-147041       c
            1547-8970           AC079438.30        137703-145126       c
FEATURES             Location/Qualifiers
     source          1..8970
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 61.57 cM"
     gene            1..8970
                     /gene="Kcna1"
                     /gene_synonym="Kca1-1; Kv1.1; MBK1; mceph; Mk-1; Shak"
                     /note="potassium voltage-gated channel, shaker-related
                     subfamily, member 1"
                     /db_xref="GeneID:16485"
                     /db_xref="MGI:MGI:96654"
     exon            1..1546
                     /gene="Kcna1"
                     /gene_synonym="Kca1-1; Kv1.1; MBK1; mceph; Mk-1; Shak"
                     /inference="alignment:Splign:2.1.0"
     exon            1547..8970
                     /gene="Kcna1"
                     /gene_synonym="Kca1-1; Kv1.1; MBK1; mceph; Mk-1; Shak"
                     /inference="alignment:Splign:2.1.0"
     CDS             2078..3565
                     /gene="Kcna1"
                     /gene_synonym="Kca1-1; Kv1.1; MBK1; mceph; Mk-1; Shak"
                     /note="MKI; voltage-gated potassium channel subunit Kv1.1;
                     megencephaly; brain potassium channel protein-1"
                     /codon_start=1
                     /product="potassium voltage-gated channel subfamily A
                     member 1"
                     /protein_id="NP_034725.3"
                     /db_xref="CCDS:CCDS20555.1"
                     /db_xref="GeneID:16485"
                     /db_xref="MGI:MGI:96654"
                     /translation="MTVMSGENADEASTAPGHPQDGSYPRQADHDDHECCERVVINIS
                     GLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRL
                     RRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYP
                     ESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTIHRIDNTTVIYTSNIFT
                     DPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQ
                     EGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLF
                     IGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLC
                     AIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSSPNLASDSDLSRRSSSTIS
                     KSEYMEIEEDMNNSIAHYRQANIRTGNCTTADQNCVNKSKLLTDV"
     regulatory      8937..8942
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kcna1"
                     /gene_synonym="Kca1-1; Kv1.1; MBK1; mceph; Mk-1; Shak"
                     /note="hexamer: ATTAAA"
     polyA_site      8962
                     /gene="Kcna1"
                     /gene_synonym="Kca1-1; Kv1.1; MBK1; mceph; Mk-1; Shak"
                     /note="major polyA site"
ORIGIN      
        1 gggggctcct cagaggctcc gcagcggtgg aaggactgga gctgctggct gcctcctccg
       61 gtgcagcctg tatccaggtg cagcggcact ggggacgcgg tgcatatccc ttgctcagac
      121 tgccactgtg acccttgcgc gaatatgtcc ggagcctaga aagtggtcct gagcggcaga
      181 gggccactgg gtgggtgggt gagtggggag gttcggaagg caggactgag ggtaggaagc
      241 gaattgggcg acttgcttct cacgtttgtc ccaattagca ccaagttggc agacaatcca
      301 caaatccacg acacctttgc ttgtccgccc ccgccgcctc ccttccccct cccgtcaaat
      361 tctctgcatt tcagaatatt ctgactgtaa gaaaacttca gctccccctc ctcggttcaa
      421 gtgaaacaga cacttggcac caccttctcc cagtaacact gtgtggatga atcccggaga
      481 tcctcaactg cagcgcttac caaactgcac cctttggagt gtggctggcg tggggttggg
      541 gggctagggt gggctgagca gagaggcctc tgggggagag gcggggtggc gcggaggagc
      601 gagatgcagg agcaagatcg cctgtgtgac tgcatctaaa gcagactggt ccaaggagtt
      661 ctgccaggga caccaccgcc tgcattgcgt cggacctgac catctccaat gtgaaattcc
      721 cggggaaggt cgctcgcagc ggagggccgt gcgtgggagg ggctgccggc cgccgggaaa
      781 gaggagttgg tggtgggctt ttcggggggg ggggcggaag aaaagctgtg caggcaagga
      841 tgggaactga atgacaaccc ccctctgcca aaccaccccc tcatattttc catctacctc
      901 ctcgctcctg ccctcccccg ccctccccaa cccacgcccg ggtgggccaa tcgctgctcc
      961 gcattccagg cgctttctca ggtttctgct gatcttgcag cgcccagaaa tggaccgagc
     1021 gaacctgcgg ccgcacgctc cctgccccac tcggagctgc tgaaggctcg cggcgcgccg
     1081 cggagagagg tccgtgctgt ggtagcgcag gttaccggag agccatgtag agccaggctt
     1141 tgagccgccc gcctccctcg ggatcgaatc aagggctccc gtagtgttca gaggggggcg
     1201 agagtgcagc ttatcgccat ttgcttgggt gattccggag aaggtggcct ttttgtcttt
     1261 ccaccccgca tcctccggga ctcccttccc cagagagagg acagcgtctc caggttgctt
     1321 gcaccgtgtg aggatggggg tagggtacgg acgtttcctc cgtagctgct cgataaaacg
     1381 atcggactcc tgagaggaga aggacgggaa acgcgagggg ccccggagcc tctcgcacgc
     1441 tgctgcggtg gtggcggctg ctcgttccgg ctgctgcaaa ggcgacctgc cgcattcaga
     1501 ctctccgccg actcagcaca gcctctgcgc caagccggcc cgccagcgtc catcgatcgc
     1561 cccggtggga gcttagaagg cggcaggcga agaggggtag gaggggggga gagccaagga
     1621 gcagcaaagt gggtgacagg cctggggagc tgctgagttg gcactgcacc gtgtcctaga
     1681 agggctgcag gaggggaggg gagccggggc gagccccgga agcgatggca ggtgtgcatt
     1741 aaggtgatca gagcaggaag aaaaacccat tcaccaacac aaaaacagag cacccccccc
     1801 caaaaaatac cccaagagta gcaaaaaagc ttcactgggg gccctcaggc gagaggggtt
     1861 tccaaattgc gtaaaaggca gagtggagga ggggaggtga taactagcaa agttgcagac
     1921 ttctgaacct tctggctctg aagcccctcc ctgtgagcgt ggggaagact cactttccgg
     1981 tggggggggc cgcttgggtc ccccccaccc ctactccctc gctccttcac aacccgggct
     2041 ctctcctggc ctcctacccc tgcaccctgc tttcatcatg acggtgatgt cgggggagaa
     2101 tgcggacgag gcttcgaccg ctccaggtca cccccaggat ggcagctacc cgaggcaggc
     2161 ggaccacgac gaccacgaat gctgcgagcg cgtagtaatc aacatctccg ggctgcgctt
     2221 cgaaacgcag ctcaagactc tggcacagtt ccccaacacg ctgctgggca acccgaagaa
     2281 acgcatgcgc tactttgacc ccctgaggaa cgagtacttc tttgaccgca accggcccag
     2341 cttcgatgcc atcctttatt actaccagtc cgggggccgc ctgcgcaggc cggtcaacgt
     2401 gcccctggac atgttctccg aggagattaa attttacgag ttgggcgagg aagccatgga
     2461 gaagttccgg gaagatgagg gcttcatcaa ggaagaggag cgccccctac ccgagaagga
     2521 gtaccagcgc caggtgtggc tgctctttga gtatccggag agctcaggac ctgcccgggt
     2581 tattgccatt gtgtcggtca tggtcatcct catctccata gtcatctttt gcctggagac
     2641 tctccctgag ctgaaggacg acaaggactt cacgggcacc atccaccgca tcgacaacac
     2701 cacagtcatc tatacttcca acatcttcac agaccctttc ttcattgtgg aaaccttgtg
     2761 tatcatctgg ttctcttttg agctggtggt gcgcttcttc gcctgcccca gcaagacaga
     2821 cttctttaag aacatcatga acttcatcga cattgtggcc atcatccctt atttcattac
     2881 cctgggcacg gagatagctg agcaggaggg aaatcagaag ggcgagcagg ccacttccct
     2941 ggccatcctc agggtcatcc gcttggtaag ggtgttcaga atcttcaaac tctcccgcca
     3001 ctccaagggc cttcagatcc tgggccagac cctcaaagct agtatgaggg agttagggct
     3061 gctcatcttt ttcctcttca ttggggtcat actgttttct agcgcagtgt actttgcgga
     3121 ggcggaagaa gctgagtcgc acttctccag tatccccgat gctttctggt gggcggtggt
     3181 gtccatgacc actgtgggat acggtgacat gtaccctgtg acaattggag gcaagatcgt
     3241 gggctccttg tgtgccatcg ctggtgtgct gacaattgcc ctgcccgtac ctgtcattgt
     3301 gtccaatttc aactatttct accaccgaga aactgagggg gaagagcagg ctcagttgct
     3361 ccatgttagt tctcctaact tagcctctga cagtgacctc agccgccgca gctcctctac
     3421 tatcagcaag tctgagtaca tggagatcga agaggatatg aacaatagca tagcccatta
     3481 cagacaggct aatatcagaa ctggtaactg caccacagct gatcaaaact gcgttaataa
     3541 gagcaagctc ctgaccgatg tttaaaaagc aacaggcaag ccaacaaaag ccccaaacaa
     3601 accccttggc gactcctgtc ccgctctgta gatactttac taagcagtag tctttgaatg
     3661 ctttattttg ctggcaatgc attgttgcat tgtgaatttg gggagtggcg aacctgaagc
     3721 tttcaagatc cattaaaaaa aaaaaaaacc aaacacaaag caaaaaataa aaacaaaaac
     3781 acaaaaatga cccaacaacc aactattttc atttttatta aaaagaaaag aaagaggatt
     3841 ttcttataaa tgctctccat taagtagtct gtgtgaaata agacgatttc cttgtcctga
     3901 agtatttcca atcttttggc ttaaggtttt gttttcgttt ttttatttat ttatttttgt
     3961 tttgttttgt tttttcccct aaaaatcaga tgaccactta ggaatataaa aattcaaatc
     4021 tgcatggaac tccactctaa acttttgcaa accgcacagc acatttcaga tagtgtgctc
     4081 tgtggaacag tttctaacag cttcagtggt cagtgtgggg gggggcaatg cttttatttt
     4141 gatcaactga attgcataca aggttaacaa aatctggact aattgagaat ggttcagaaa
     4201 gcaccttgca aatctgatac tgggcccaat ctgttgggat tctctatctg ccccattctc
     4261 ctaaatccag tctattctct aagaaaaggg taacttgatt aaatgagttg attcatctgt
     4321 agggctgcta agttctatca actgcagatg atccaaatgt agtttttttt aaccaatcct
     4381 gacccctgac ccctgacctt cagaagtgga tgtaaaacct taccctcctt attgcaagag
     4441 cacaagagtt aaatggtaag catgtttgaa tctgataaca tttattttat aatcgcatgc
     4501 cgagaaagtt aacccagaca atagggaata agcttacgtt gaaattgact cttctaaata
     4561 taggcccttt tcatttgcat tcaccaaaag tgcactcctt catttattaa ctcttttctt
     4621 agcaactaaa gtactgtatt taagtacata cattagatgg ggacaatccc ttttcggagc
     4681 tcaaagcatg ttctcttagt cagcattatg gcctatttga ttaagatata ccttgaatta
     4741 attaatgcat gatttcagtg ataaaaatta gaaaatacta aaaattacaa gtctgtggga
     4801 cgaaaggccc aaagaaacac ttggggtggg ggtggggtgg gggacactcc cgtcagtttt
     4861 cccgcctttg ctcagggaaa tgccaaggtt ctgtgcaggt ttagacagag agaggaccaa
     4921 tatgcccatc ctttaaggga aaattgtgga aaactaaata agtcatcaag gtatttaata
     4981 gacctaagac aagcattctt tctagctgaa cataaataca agcaaaacaa acaaacaaac
     5041 aaacaaacaa aaaaaggtgc aatattgcat ggtttcttgg tgcattctta ggatgtaact
     5101 gataaagctg acctcttcat gcatccagag cagagccaat ttcttttttg cagtcatgat
     5161 ttgaagtcta tagagacttc agccctcccc ctgaggctcc ctgaagaaac tcagccaatt
     5221 gatttaatac ttgcttagtg cctttatctg tacccacagt gaactgcaga aagtgcctct
     5281 gtaactcagc tgggaagtta tttaacagaa gggaggaagg gttggggcac agaccttttg
     5341 cttttcgttt tctttgtttt tttttttttt ccatcctcac cgtctcactt caccactgtg
     5401 agaagacctc tccaccctca gagcccccaa agaagagaga gagaaagcag gtgctgtctc
     5461 tcttggccct ctaccgggct tagttggtct ctttggcagc ctgactctgg atatgaactg
     5521 agacccatct ttgaactgga cacgaactat aaaccagttc tattctgttc tgtgctgttt
     5581 tgtttcttct tgatcaaaag ccaagagaaa tgtttttggg aatgtggaag gccactctgg
     5641 acatacaaag cttcctcagg ttcagtggct ccgtctcccc catctctccc tgtcagctat
     5701 agcacttcgc agatctctga tagtctgatc tttggggata ttgttgtgaa tcatggggac
     5761 acttatctca cagtgactcg ccatacgcca gccatcttgg gtcaacctcc tatgtatctt
     5821 tcctatgatg ctcctccgat tgtcccactg ggaagtcact tcactggctg aacatctgac
     5881 tgctgctgcc ccagccactg aatccagaga atggtgggga ccccatgtcc agctgataga
     5941 tcatcatatc acacaggctc tggagtctag cagcttttca ccaacagaga ggcgttcatt
     6001 gcctttttaa ggacgccgga gtgggggatc ttcattctgc ttttagcatg tggctgccta
     6061 ctactgtttg ccttacattc ttgcctggct tcttctggaa tcttccctgg ttcttccgta
     6121 cctttccccc acccaatctt cagactagaa gtgaggccat aaaccaagaa actatgagga
     6181 catccaggct atctagctca tttggaagga gatggacatt ttctttccct gtgcaatttt
     6241 tgtgagtctt cagggtgttc caacatatat cctagaagat gaggtgccaa gaactgccca
     6301 gcctctgact atagggcact ctaccctgct gtgtgtcgct caatctttga accttagatc
     6361 tttccttcca catgattgca agtgtccagt tcggagaaaa atgccaactc ctcccccact
     6421 ctccaggaat atcttgaact tttattttga ctctgagatc taggacacaa cagaactctg
     6481 tccacagcaa taatccactc agtactatgg gatggatggg ttagaagatg cgttactgag
     6541 cctgagactg gtcagccagc cactggacat gcgacctgcc tcttgtagcg gtgccctgga
     6601 caggttgaca ctctggtgta tgttacaaga caaagtgctg catgtggtga agtggtctgc
     6661 ctggggctgt gggatgtgct gctgttatga atttggagtg aatgggggat acagatgctg
     6721 gttatccatc tgtagctcat tgcagtgagc gtgatgacag ggggcacggg gattatctgt
     6781 gtagcatagg catgtgacct ttgactaagc tcttacccct gcactgtaat gtgctgaaat
     6841 gtctttgtag acctgaaggt gcacttaact aaactgccta ctaaggaatg actctcatct
     6901 ggtccacttc acactccctt ccccaggtgt ttgccctttc acccccttct taggtattga
     6961 gccttgatag ctcaagcccc aatgctaaga cccgttttct ctgtaaggag aagacttatg
     7021 atatactgat agccatagcc catctcttcc aacatgtagg gccctagttc catagggtgc
     7081 ccttggaagg atcaggtcat cctgtggcta ttagccatcc cagaatctct gaagtgctta
     7141 actcacttca agtgatctga atcagagaga ccaaagatat taattttctc tgtcctcaga
     7201 tttctagaag acagactatg gccaggaaag gctttatttt ggtttgggct ttctctctct
     7261 cctttctcca tctgtacaca tcccctacct cactccccac ttgagaccta aattttgaag
     7321 ctcaatgacc ctgttcactg ggagtgtgtt tgtgggttag tccagaatat caggtccaac
     7381 aatttccccc acactgtagt caatggacag tcattttctc taacacaaaa ctgtgtggtg
     7441 gatttagatt ccactgaggt ggaactgggg ttgccacagc cttgatcttc ttgagactag
     7501 acagaacaag agtggtggct gagaaataca ttttcctaag tagaaatgag gtacaaccca
     7561 taaaggactt tcttcacagt gagcgtagca gttacgactt tttcaaatta gagtctaaag
     7621 gaatcagtaa agaagtaaaa aagaaaaaaa attcgttttc aacctcatgc ttcatataag
     7681 aggcctcaaa gcacatgctt atttttttta aagcaacttt aaattttaat tccttgtttg
     7741 gtagattagc ttgaacaaaa agtaggaaat gaacgttagc agaaggcagt tccccatttt
     7801 cttccaggga tgacttattc ctgggagcag tgagaattgg tgggtggtaa ccatccatag
     7861 tataaaattg ttagaaagag tataaactgc caaacaacca cattatcttc cagccctttt
     7921 ccaagagtga agccttttga tatttatatt cacttggaga agacaaacaa actagagttt
     7981 gaggaataga cccaggcttg gttgaagtgt tctctcaggt ggtggactct cacctacagc
     8041 agggtccagc aggacttaca tttatagcac aggacttcag ggtatatgca gacatgtcta
     8101 gaatgactca ggtaaccctt caagaattgt accttacttg ttgcttttgt aaagaagcaa
     8161 gcaggaactg aattgttaac caaaagtatt ccattacctt gggccactgt gcaaactcat
     8221 tcagggcata cacataatgt taaaagctcc aggatcaagt ggcagcctct tttctcattg
     8281 actcatggga gtgccaatgt gtaggaaaag cattaggctc tgctgtcttt cgtacagctt
     8341 ggggaaggtt gacactagtc acagtgattt tcatatagga gttattaggg aatttgtgat
     8401 atgagacttc aaaagatcta gaaagccctc cccccctaaa tcaaagaaga agaagtggat
     8461 aaggaaagaa aatggaagga gaaagtaccc acagagtatg ctaggtcata actgtctttc
     8521 ctcttcaaaa cttgcagaag tctccttctt caatgcactg tttaggagtc acgtacgaag
     8581 cagccataag ttggtgacat ggtctctatg acatacctct aagatgaaag atagactatt
     8641 cctgaggcta aaactacagt ctagaagtat taatctgatg tgcaccctca ggacgacaaa
     8701 ccattgaagc tgattctgaa gttctgtttt ctttcttggc tttgccaatt gcttcctcct
     8761 tgagttaagg acacgtctca tctcatcacc cctgcacttg ccctgcccta accgtttact
     8821 atgttgggtt gaggatactg aaagttacga atggagaacc taaggatgcg catagttttc
     8881 atctatgcaa ttttacttgg ttctgtcact tcatgatctg ttcatatttg gcatcaatta
     8941 aagataattt ttaaggatct tatcatggaa
//
