LOCUS       NM_028974               3036 bp    mRNA    linear   ROD 13-FEB-2025
DEFINITION  Mus musculus kelch repeat and BTB (POZ) domain containing 13
            (Kbtbd13), mRNA.
ACCESSION   NM_028974 XM_134954 XM_917857
VERSION     NM_028974.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3036)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3036)
  AUTHORS   de Winter,J.M., Bouman,K., Strom,J., Methawasin,M.,
            Jongbloed,J.D.H., van der Roest,W., Wijngaarden,J.V.,
            Timmermans,J., Nijveldt,R., van den Heuvel,F., Kamsteeg,E.J., van
            Engelen,B.G., Galli,R., Bogaards,S.J.P., Boon,R.A., van der
            Pijl,R.J., Granzier,H., Koeleman,B., Amin,A.S., van der Velden,J.,
            van Tintelen,J.P., van den Berg,M.P., van Spaendonck-Zwarts,K.Y.,
            Voermans,N.C. and Ottenheijm,C.A.C.
  TITLE     KBTBD13 is a novel cardiomyopathy gene
  JOURNAL   Hum Mutat 43 (12), 1860-1865 (2022)
   PUBMED   36335629
  REMARK    GeneRIF: KBTBD13 is a novel cardiomyopathy gene.
REFERENCE   3  (bases 1 to 3036)
  AUTHORS   de Winter,J.M., Molenaar,J.P., Yuen,M., van der Pijl,R., Shen,S.,
            Conijn,S., van de Locht,M., Willigenburg,M., Bogaards,S.J., van
            Kleef,E.S., Lassche,S., Persson,M., Rassier,D.E., Sztal,T.E.,
            Ruparelia,A.A., Oorschot,V., Ramm,G., Hall,T.E., Xiong,Z.,
            Johnson,C.N., Li,F., Kiss,B., Lozano-Vidal,N., Boon,R.A.,
            Marabita,M., Nogara,L., Blaauw,B., Rodenburg,R.J., Kusters,B.,
            Doorduin,J., Beggs,A.H., Granzier,H., Campbell,K., Ma,W.,
            Irving,T., Malfatti,E., Romero,N.B., Bryson-Richardson,R.J., van
            Engelen,B.G., Voermans,N.C. and Ottenheijm,C.A.
  TITLE     KBTBD13 is an actin-binding protein that modulates muscle kinetics
  JOURNAL   J Clin Invest 130 (2), 754-767 (2020)
   PUBMED   31671076
  REMARK    GeneRIF: KBTBD13 is an actin-binding protein that modulates muscle
            kinetics.
            Erratum:[J Clin Invest. 2024 Feb 01;134(3):e179111. doi:
            10.1172/JCI179111.. PMID: 38299595]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC114645.9.
            
            On Mar 14, 2022 this sequence version replaced NM_028974.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK048611.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3036              AC114645.9         135916-138951
FEATURES             Location/Qualifiers
     source          1..3036
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 35.28 cM"
     gene            1..3036
                     /gene="Kbtbd13"
                     /gene_synonym="5430433E21Rik"
                     /note="kelch repeat and BTB (POZ) domain containing 13"
                     /db_xref="GeneID:74492"
                     /db_xref="MGI:MGI:1921742"
     exon            1..3036
                     /gene="Kbtbd13"
                     /gene_synonym="5430433E21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..1443
                     /gene="Kbtbd13"
                     /gene_synonym="5430433E21Rik"
                     /codon_start=1
                     /product="kelch repeat and BTB domain-containing protein
                     13"
                     /protein_id="NP_083250.1"
                     /db_xref="CCDS:CCDS57682.1"
                     /db_xref="GeneID:74492"
                     /db_xref="MGI:MGI:1921742"
                     /translation="MPPGPEVPVQVWVDGQLFQAEQSLLVEHCGFFRGLFRSGMREAR
                     AAEVRLGALSASGFRTALRVLRGERPALAAEDELLQAVECAAFLQAPALARFLEHSVT
                     SDNCSLLCDAAAAFGLRDVLHSAALFIRDGSHELVAQLELPEARAYVAALRPSTYVAV
                     STHTPTPGFLEDASRTMCFLDEEEDAWRTLAALPLEASTLLAGVATLGNKLYIVGGVC
                     GASKEVVELGFCYDPEGGTWCEFPSPHQPRYDMALAGFEGRLYAIGGEFQRTPMSSVE
                     CYDPATGCWSFVADLPQPATGVPCAQARGRLFVCLWRPADITAVVEYVVQMDKWLPVA
                     ELCRSQSYGHFMVAHRDSLYVVRNGPSDDFLHCAIDCLNLVTGQWTSLPGQFVNSKGA
                     LFTSVVRGDTVYTVNRVSTLVYAIEDGTWRLLREKAGFPRPGSLQTFLLRLPPGTTGP
                     VATALPEL"
     regulatory      3012..3017
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kbtbd13"
                     /gene_synonym="5430433E21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3036
                     /gene="Kbtbd13"
                     /gene_synonym="5430433E21Rik"
                     /note="major polyA site"
ORIGIN      
        1 agagtcagtg gcccctggca aatctaggcc ccccagcggc agcagcctcc acccctctgg
       61 ctcatcatgc ccccaggccc cgaggtccca gtgcaggtgt gggtggacgg tcaactcttc
      121 caggcggagc agtcgctgct ggtggagcac tgcggcttct tccgcgggct tttccgctct
      181 ggcatgcggg aggcgcgcgc cgcggaggtg cgcctgggcg cgctgagcgc ctccggcttc
      241 cgcacggcgc tgcgggtgct gcgcggagag cggccggcgc tggcggccga ggacgagttg
      301 ctgcaggcgg tggagtgcgc cgcgttcctg caggcgcccg cgctcgcgcg cttcctggag
      361 cacagcgtca cgtcggacaa ctgctcgctt ttgtgcgacg cggccgccgc cttcggcctg
      421 cgcgacgtgc tccacagcgc tgcgctcttc atccgcgacg ggtcgcacga gctggtggca
      481 caactggagc tgcccgaggc ccgagcctac gtggcggcgc tgcgacccag cacctacgtg
      541 gcggtgagca cgcacacgcc cacaccgggc ttcctagagg atgcgtcgcg caccatgtgc
      601 ttcctggacg aggaagagga cgcatggcgc acgctggccg cgctgcccct ggaggccagc
      661 acactgctgg cgggtgtggc caccctgggc aacaagctct acatcgtggg tggcgtgtgt
      721 ggtgccagca aggaagtagt ggagctaggc ttctgttacg acccagaggg tggcacctgg
      781 tgcgaattcc ccagccctca ccaaccgcgc tatgatatgg cgctggctgg cttcgaaggc
      841 cgcctctatg ccattggtgg cgaattccag aggacaccca tgagctccgt ggagtgctat
      901 gatcccgcca caggttgctg gagcttcgtg gcggacttgc cacagccggc tacaggggtt
      961 ccctgtgccc aggcacgtgg ccgcctcttc gtgtgcctgt ggaggccggc agacatcact
     1021 gccgttgtcg agtatgtggt gcaaatggac aagtggctgc cagtggctga actgtgtcgt
     1081 tcacagagct acggtcactt tatggtggcc catcgcgata gtctctatgt agtacgaaat
     1141 ggaccttccg atgatttcct gcactgtgcc atcgattgcc tcaacctggt cacaggccag
     1201 tggacatcgc tacctggcca atttgtcaac agcaagggag cactcttcac gtctgtagtg
     1261 cgtggggaca ccgtttatac tgtcaaccgt gtatccacgt tggtctatgc cattgaagat
     1321 ggcacctggc ggctgctcag ggaaaaggct ggctttcctc ggcctggctc tttacagacc
     1381 tttcttctgc ggctgcctcc tggcactact ggacctgtgg ccaccgcact gccagagttg
     1441 tgagcttgga atgacttcag aagataacac aagtctccat gaaccttggc ggtgtcctca
     1501 tgagccttga ctgtgtgatt ggggagctct tgggaactcc tttttcccta ttaagacact
     1561 caggtttgct ttctggtggt gcgggtgtcc acgaagccct gagcaacaca ggtgcttggg
     1621 tccttaaatc tcttgggctc tgttgggagc tggtgggtca caatctcagg gaaaagggtg
     1681 gggttacaat ttgagcaatc cggacttgta ggcgaataca agtctagcta tagctactat
     1741 agctagaagt gggttaagtg atgttaaacc aatctgctaa ttagcaggca caaaatgtca
     1801 atacaacatt ggcctgtagt tgtcagctgt ggcacagaga agcttgaaga caataccagc
     1861 tttcttaaca caaaggtcag gatgagaaaa caggtctaca cataatttgc ctccacccac
     1921 aagctgacag caccatgctg attttaaaaa gcaaacaacg caccgtgcag taagaagaat
     1981 actgaagcag tcagcctgga agaacagctt cggatcacag agtctgagtg tttcaggagc
     2041 agagaggggg aagactggac aagacaggat cttggtaagc tccagccttt ttaagctgaa
     2101 cagcggaaga tggaggcatt tcgccagtga ggctggacta aattatagca aaagaaactc
     2161 agctgagcct gaagcaagaa ggtgggaggg agcaagggtt ccctacagta gctttaagga
     2221 ctggaatgga aagggagtac ccgggtgtaa atccttgacc tatctttttt gtaatcactg
     2281 taactgtaga ctgttaatct cctgacttca ggttacttaa ggtggatgga gcctagccct
     2341 gctgacctct cagggcattt cttcatagat atgccacagg ctccacctct cttgtaatct
     2401 ctgctgtggc cattccctga gcctacagtg ctatccctct tcctctctgt cagttccata
     2461 cccacctcct ctctgcaggc ttgcctgagc cagctcctgt tttcctgact tggctgccag
     2521 cattgctcat tgatctctgt gttggatatg cagccatacc tgtttgcaga tagaaggcgt
     2581 aggggtccaa tacttttaac tgagccaggc acccccttgc ctgcggaatg aaatgaagtc
     2641 ttacaagaac cactagttag gggtctgcta ctgactgaca ggtgctgtta aacagctctc
     2701 atcttaaaag caatacccag acccagcttc tgttacagat gcctgcttca gccctacagc
     2761 ctggccatat cccaggtaaa tgtctctcaa tggtccggta tagtctctat cctccaggac
     2821 tcaaggctca tagaaaaccc tggcttcaga agtcgagaat acagccttgg catggtactc
     2881 cctgagcatg gagccttgtg ttgggccgtc gattgctacc tcttccctga tgtgtatccc
     2941 aaacttgaaa taagttgcct ttgggagtgt ggaattgtct agccttttag tctagtctga
     3001 tgaatcacaa caataaactc tgacatttgt atccta
//
