LOCUS       NM_030697               2652 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus KN motif and ankyrin repeat domains 3 (Kank3),
            transcript variant 1, mRNA.
ACCESSION   NM_030697
VERSION     NM_030697.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2652)
  AUTHORS   Guo,S.S., Seiwert,A., Szeto,I.Y.Y. and Fassler,R.
  TITLE     Tissue distribution and subcellular localization of the family of
            Kidney Ankyrin Repeat Domain (KANK) proteins
  JOURNAL   Exp Cell Res 398 (1), 112391 (2021)
   PUBMED   33253712
  REMARK    GeneRIF: Tissue distribution and subcellular localization of the
            family of Kidney Ankyrin Repeat Domain (KANK) proteins.
REFERENCE   2  (bases 1 to 2652)
  AUTHORS   Logunova,N., Korotetskaya,M., Polshakov,V. and Apt,A.
  TITLE     The QTL within the H2 Complex Involved in the Control of
            Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1
            Gene
  JOURNAL   PLoS Genet 11 (11), e1005672 (2015)
   PUBMED   26618355
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2652)
  AUTHORS   Quintens,R., Verreet,T., Janssen,A., Neefs,M., Leysen,L.,
            Michaux,A., Verslegers,M., Samari,N., Pani,G., Verheyde,J.,
            Baatout,S. and Benotmane,M.A.
  TITLE     Identification of novel radiation-induced p53-dependent transcripts
            extensively regulated during mouse brain development
  JOURNAL   Biol Open 4 (3), 331-344 (2015)
   PUBMED   25681390
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2652)
  AUTHORS   Shalom-Barak,T., Zhang,X., Chu,T., Timothy Schaiff,W., Reddy,J.K.,
            Xu,J., Sadovsky,Y. and Barak,Y.
  TITLE     Placental PPARgamma regulates spatiotemporally diverse genes and a
            unique metabolic network
  JOURNAL   Dev Biol 372 (1), 143-155 (2012)
   PUBMED   22967998
REFERENCE   5  (bases 1 to 2652)
  AUTHORS   Zhu,Y., Kakinuma,N., Wang,Y. and Kiyama,R.
  TITLE     Kank proteins: a new family of ankyrin-repeat domain-containing
            proteins
  JOURNAL   Biochim Biophys Acta 1780 (2), 128-133 (2008)
   PUBMED   17996375
REFERENCE   6  (bases 1 to 2652)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   7  (bases 1 to 2652)
  AUTHORS   Abe,K., Yuzuriha,M., Sugimoto,M., Ko,M.S., Brathwaite,M., Waeltz,P.
            and Nagaraja,R.
  TITLE     Gene content of the 750-kb critical region for mouse embryonic
            ectoderm lethal tcl-w5
  JOURNAL   Mamm Genome 15 (4), 265-276 (2004)
   PUBMED   15112104
REFERENCE   8  (bases 1 to 2652)
  AUTHORS   Xie,T., Rowen,L., Aguado,B., Ahearn,M.E., Madan,A., Qin,S.,
            Campbell,R.D. and Hood,L.
  TITLE     Analysis of the gene-dense major histocompatibility complex class
            III region and its comparison to mouse
  JOURNAL   Genome Res 13 (12), 2621-2636 (2003)
   PUBMED   14656967
REFERENCE   9  (bases 1 to 2652)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK002623.1 and AI847524.1.
            
            On Oct 21, 2017 this sequence version replaced NM_030697.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK002623.1, SRR7345562.773059.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2634              AK002623.1         2-2635
            2635-2652           AI847524.1         1-18                c
FEATURES             Location/Qualifiers
     source          1..2652
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 17.98 cM"
     gene            1..2652
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /note="KN motif and ankyrin repeat domains 3"
                     /db_xref="GeneID:80880"
                     /db_xref="MGI:MGI:1098615"
     exon            1..43
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /inference="alignment:Splign:2.1.0"
     exon            44..103
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..2445
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ankyrin repeat domain 47; KN motif and ankyrin repeat
                     domain-containing protein 3; ankyrin repeat
                     domain-containing protein 47; putative KN motif and
                     ankyrin repeat domains 3"
                     /codon_start=1
                     /product="KN motif and ankyrin repeat domain-containing
                     protein 3 isoform 1"
                     /protein_id="NP_109622.1"
                     /db_xref="CCDS:CCDS28630.1"
                     /db_xref="GeneID:80880"
                     /db_xref="MGI:MGI:1098615"
                     /translation="MAKFVLNQNLPDLGGPPLYPGPTGSARSPSSPYSVETPYGFHLD
                     LDFLKYVEEIERGPASRRTPGPPHARRPRASRTGLAGARSPGAWTSSESLASDDGGAS
                     GALSPGAFPGLSLPPLSPRSLSRNPRVEHTLLETSRRLEQAQARERALSPARAVTRSP
                     RGSGRSSPAPNPALASPGPAQLQLVREQMAAALRRLRELEDQARALPELQEQVRALRA
                     EKARLLAGRVQPEQEVEIEARPDKLAQLRRLTERLATSDRGVRSRASPRAEDPDGLAA
                     RRSEGALQVLDPGSRTPDGEPRTRETGTEVVPETREVDAQAVPETGEAGVEVVPETVE
                     VDTWVTEELLGLPEAAERELELLRTSLEHQRGVSELLRGRLRELEEAHEAAVTRPQSR
                     DVAAQTTLGCTEKTTQTELPVENQPRPTAGDEMAPVGILKSIMKKKDGIPGAQSSQGP
                     KSLQFVGVLNGEYESSSSEDGNSDDEDGVAEHPRSSSSGSDDSSGGSDAGTPGPHNDK
                     DAGDCELETHPELTAGREGRCELNPRLREACIALNQQLNRPRGVTSRDGNAARLVAQE
                     WFRVSSQKRSQAESVAGVLRGVKSLGPELLAYVVNLADGNGNTALHYSVSHGNLAISS
                     LLLDTGVCDVNHQNRAGYSALMLAALTSVGQEEEDMAVAQRLFSMGDVNAKASQTGQT
                     ALMLAISHGHQDMVAALLECGADVNVQDADGATALMCASEYGRLDTVQLLLAQPGCDL
                     TILDNEGTSALAIALEAEQDEVAALLHAHLTSNHQGQSSTGSPTAKECNDK"
     exon            104..1354
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /inference="alignment:Splign:2.1.0"
     exon            1355..1454
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /inference="alignment:Splign:2.1.0"
     exon            1455..1652
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /inference="alignment:Splign:2.1.0"
     exon            1653..1740
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /inference="alignment:Splign:2.1.0"
     exon            1741..1957
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /inference="alignment:Splign:2.1.0"
     exon            1958..2103
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /inference="alignment:Splign:2.1.0"
     exon            2104..2304
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /inference="alignment:Splign:2.1.0"
     exon            2305..2394
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /inference="alignment:Splign:2.1.0"
     exon            2395..2637
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2618..2623
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /note="hexamer: AATAAA"
     polyA_site      2637
                     /gene="Kank3"
                     /gene_synonym="0610013D04Rik; Ankrd47; D17Ertd288e; NG28"
                     /note="major polyA site"
ORIGIN      
        1 gggctcgggt gcggtgcggg cgctgccggg gcttctcatt caggctgtct ggtggctgct
       61 ccaggaaaca tggccaagtt tgtcctgaat cagaaccttc ctgacctggg cggccctccc
      121 ctgtacccag gccccactgg aagtgcccgc agccctagct ctccctattc tgtggagacg
      181 ccctatggct tccacttgga cctggacttc ctcaaatacg tggaggaaat cgagcgtggc
      241 cctgcctctc gccgaactcc aggacctcct catgcacgcc gcccgcgcgc gtctcgaacg
      301 ggcctcgcgg gagcgcggag cccaggagct tggacttcca gcgaatccct ggccagtgac
      361 gacggcggag cctcgggtgc actctctcct ggtgcgttcc cggggctctc gctacctccg
      421 ctgtcgccac gctccttgtc gcgcaatccg cgcgttgagc acacgctctt ggagaccagc
      481 cgacgactgg agcaggcgca ggctcgggag cgcgcgctca gcccggcccg cgcagtcaca
      541 cgcagtccgc gcgggtccgg ccgtagcagc cccgccccta accccgccct tgcctccccg
      601 ggccctgccc agctgcagct agtgagggag cagatggccg cggcgctgcg gcgcctgcgt
      661 gagctcgagg accaggcgcg cgctctgccc gagctgcagg agcaggtgcg cgcgctgcgt
      721 gccgagaagg cgcggctact ggccgggcgc gtgcagccag aacaagaagt agagatcgag
      781 gcgcgcccag acaagctcgc ccagcttcgg cgcctcaccg agcgtctggc cacctcggat
      841 cgtggagtgc gctccagggc tagcccccgg gcagaggatc ccgacgggtt ggctgccagg
      901 cgcagcgaag gagcgctgca ggtgctcgac ccggggtcta ggacacccga tggggaaccc
      961 cggactcggg agacgggcac cgaagtcgtg cctgagaccc gagaggtgga tgcccaggca
     1021 gtacccgaga caggggaggc tggagtggag gtggtccctg agaccgttga ggtggacacg
     1081 tgggtgactg aggagctcct agggttgcct gaggctgcag agcgtgagct ggagctgctc
     1141 cgcaccagct tggagcatca gcgaggggtg agcgaactct tgcggggccg attgagggag
     1201 ttggaggagg cccacgaggc cgcagtgacc aggcctcagt ctcgcgacgt tgctgcccag
     1261 actacattgg gttgcactga gaaaaccaca cagacagagc tgccagtgga gaaccagccc
     1321 agacccacgg ctggagacga gatggcccct gttggcatcc tcaaatccat catgaagaag
     1381 aaagatggta ttccaggtgc acaatccagt cagggaccca agagtctgca gttcgttggg
     1441 gtcctcaacg gagagtatga gagttcctcc agtgaggatg gcaacagcga tgatgaagat
     1501 ggtgttgctg aacaccccag gagtagctct tctggatcag atgatagcag tgggggatct
     1561 gacgctggaa cccctggccc ccacaatgac aaagatgctg gggactgcga gcttgagaca
     1621 catccagagc tgacggcagg gagagaaggg aggtgtgaac tgaacccccg tttgagggag
     1681 gcttgcattg ctctgaatca gcagctgaac cggccacgtg gagtcaccag cagagatggc
     1741 aatgcagcac gccttgtggc ccaggaatgg tttcgagtgt ccagccaaaa acgctctcag
     1801 gcagagtctg tggctggggt tcttcgaggg gtgaaaagcc tggggcctga gctgctggct
     1861 tatgtggtga acctggctga tggcaatgga aacacagctc tgcattacag cgtgtctcat
     1921 gggaatctcg ccatttccag cctgctactg gatacagggg tctgtgatgt gaatcaccag
     1981 aatagagctg gctactctgc cctcatgttg gctgcactca cttctgtagg acaagaggag
     2041 gaagacatgg ctgtggccca gagacttttc agtatgggtg atgtcaatgc caaggctagc
     2101 cagactggac agacagccct catgctggcc atcagccatg gccaccagga catggtagct
     2161 gccttgctag aatgcggggc tgatgtcaat gtacaggatg ctgatggggc cacagcactg
     2221 atgtgtgcca gcgagtatgg acgccttgat acagttcaat tgttgttggc ccagccaggt
     2281 tgtgacctaa ccatcttaga caatgagggc acaagtgccc tggccattgc actggaggct
     2341 gaacaggatg aggtggctgc actgctccat gcccacctga catcaaacca ccagggacag
     2401 tcttccacag ggtctcccac tgcaaaggaa tgcaatgaca aatgaggaac ctctacctct
     2461 gtgagctgct aactacatct agactctctc tgctgtctga atcacagcag ggcaccttga
     2521 gaagatgctc cctctagctt gttaggatgc tgaggggaaa gagtgaggca aagcctgggt
     2581 aatgccatat ccctcaactc acttcatgaa acatcctaat aaaagtattt ctactaaaaa
     2641 aaaaaaaaaa aa
//
