LOCUS       NM_177357              15439 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus kalirin, RhoGEF kinase (Kalrn), transcript variant 1,
            mRNA.
ACCESSION   NM_177357
VERSION     NM_177357.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 15439)
  AUTHORS   Liu,S., Qi,R., Zhang,J., Zhang,C., Chen,L., Yao,Z. and Niu,W.
  TITLE     Kalirin mediates Rac1 activation downstream of
            calcium/calmodulin-dependent protein kinase II to stimulate glucose
            uptake during muscle contraction
  JOURNAL   FEBS Lett 596 (24), 3159-3175 (2022)
   PUBMED   35716086
  REMARK    GeneRIF: Kalirin mediates Rac1 activation downstream of
            calcium/calmodulin-dependent protein kinase II to stimulate glucose
            uptake during muscle contraction.
REFERENCE   2  (bases 1 to 15439)
  AUTHORS   Niu,F., Han,P., Zhang,J., She,Y., Yang,L., Yu,J., Zhuang,M.,
            Tang,K., Shi,Y., Yang,B., Liu,C., Peng,B. and Ji,S.J.
  TITLE     The m6A reader YTHDF2 is a negative regulator for dendrite
            development and maintenance of retinal ganglion cells
  JOURNAL   Elife 11, e75827 (2022)
   PUBMED   35179492
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 15439)
  AUTHORS   Grubisha,M.J., Sun,T., Eisenman,L., Erickson,S.L., Chou,S.,
            Helmer,C.D., Trudgen,M.T., Ding,Y., Homanics,G.E., Penzes,P.,
            Wills,Z.P. and Sweet,R.A.
  TITLE     A Kalirin missense mutation enhances dendritic RhoA signaling and
            leads to regression of cortical dendritic arbors across development
  JOURNAL   Proc Natl Acad Sci U S A 118 (49) (2021)
   PUBMED   34848542
REFERENCE   4  (bases 1 to 15439)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 15439)
  AUTHORS   Li,M., Ma,Y., Zhong,Y., Liu,Q., Chen,C., Qiang,L. and Wang,X.
  TITLE     KALRN mutations promote antitumor immunity and immunotherapy
            response in cancer
  JOURNAL   J Immunother Cancer 8 (2) (2020)
   PUBMED   33037113
  REMARK    GeneRIF: KALRN mutations promote antitumor immunity and
            immunotherapy response in cancer.
REFERENCE   6  (bases 1 to 15439)
  AUTHORS   Xie,Z., Cahill,M.E. and Penzes,P.
  TITLE     Kalirin loss results in cortical morphological alterations
  JOURNAL   Mol Cell Neurosci 43 (1), 81-89 (2010)
   PUBMED   19800004
  REMARK    GeneRIF: These data demonstrate important roles for kalirin in the
            regulation of cortical structure, ultrastructure, and spine
            structural plasticity.
REFERENCE   7  (bases 1 to 15439)
  AUTHORS   Cahill,M.E., Xie,Z., Day,M., Photowala,H., Barbolina,M.V.,
            Miller,C.A., Weiss,C., Radulovic,J., Sweatt,J.D., Disterhoft,J.F.,
            Surmeier,D.J. and Penzes,P.
  TITLE     Kalirin regulates cortical spine morphogenesis and disease-related
            behavioral phenotypes
  JOURNAL   Proc Natl Acad Sci U S A 106 (31), 13058-13063 (2009)
   PUBMED   19625617
  REMARK    GeneRIF: Kalirin regulates cortical spine morphogenesis and
            disease-related behavioral phenotypes.
            Erratum:[Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16890.
            Photowala, Huzefa [added]]
REFERENCE   8  (bases 1 to 15439)
  AUTHORS   Ma,X.M., Kiraly,D.D., Gaier,E.D., Wang,Y., Kim,E.J., Levine,E.S.,
            Eipper,B.A. and Mains,R.E.
  TITLE     Kalirin-7 is required for synaptic structure and function
  JOURNAL   J Neurosci 28 (47), 12368-12382 (2008)
   PUBMED   19020030
  REMARK    Erratum:[J Neurosci. 2012 Sep 5;32(36):12647]
REFERENCE   9  (bases 1 to 15439)
  AUTHORS   Chakrabarti,K., Lin,R., Schiller,N.I., Wang,Y., Koubi,D., Fan,Y.X.,
            Rudkin,B.B., Johnson,G.R. and Schiller,M.R.
  TITLE     Critical role for Kalirin in nerve growth factor signaling through
            TrkA
  JOURNAL   Mol Cell Biol 25 (12), 5106-5118 (2005)
   PUBMED   15923627
REFERENCE   10 (bases 1 to 15439)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154588.2, CT010573.10, AC154524.2 and AC165079.2.
            
            On Apr 23, 2010 this sequence version replaced NM_177357.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript, and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence because no single transcript was available for the
            full length of the gene. The genomic coordinates used for the
            transcript record were based on transcript alignments and
            orthologous data, including rat AF232669.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-114               AC154588.2         142732-142845
            115-189             CT010573.10        42626-42700
            190-304             CT010573.10        49336-49450
            305-497             CT010573.10        73726-73918
            498-1010            CT010573.10        77338-77850
            1011-1133           CT010573.10        102489-102611
            1134-1325           CT010573.10        120375-120566
            1326-1457           CT010573.10        124168-124299
            1458-1688           CT010573.10        126896-127126
            1689-1811           CT010573.10        140495-140617
            1812-2003           AC154524.2         231639-231830       c
            2004-2212           AC154524.2         225163-225371       c
            2213-2387           AC154524.2         221236-221410       c
            2388-2583           AC154524.2         212782-212977       c
            2584-2750           AC154524.2         204256-204422       c
            2751-2870           AC154524.2         196038-196157       c
            2871-3062           AC154524.2         189067-189258       c
            3063-3212           AC154524.2         186807-186956       c
            3213-3327           AC154524.2         184026-184140       c
            3328-3443           AC154524.2         181802-181917       c
            3444-3566           AC154524.2         181169-181291       c
            3567-3749           AC154524.2         174159-174341       c
            3750-3868           AC154524.2         172872-172990       c
            3869-3935           AC154524.2         168196-168262       c
            3936-4045           AC154524.2         167404-167513       c
            4046-4115           AC154524.2         158679-158748       c
            4116-4205           AC154524.2         156426-156515       c
            4206-4298           AC154524.2         151669-151761       c
            4299-4410           AC154524.2         147307-147418       c
            4411-4601           AC154524.2         145278-145468       c
            4602-4703           AC154524.2         144740-144841       c
            4704-4846           AC154524.2         143396-143538       c
            4847-4949           AC154524.2         140283-140385       c
            4950-5193           AC154524.2         85233-85476         c
            5194-5477           AC154524.2         23843-24126         c
            5478-5582           AC154524.2         22571-22675         c
            5583-5675           AC154524.2         18841-18933         c
            5676-5806           AC165079.2         154000-154130       c
            5807-5873           AC165079.2         149614-149680       c
            5874-5977           AC165079.2         149174-149277       c
            5978-6047           AC165079.2         148957-149026       c
            6048-6134           AC165079.2         148577-148663       c
            6135-6227           AC165079.2         147628-147720       c
            6228-6278           AC165079.2         146539-146589       c
            6279-6356           AC165079.2         145675-145752       c
            6357-6542           AC165079.2         142761-142946       c
            6543-6714           AC165079.2         142059-142230       c
            6715-6953           AC165079.2         130513-130751       c
            6954-7210           AC165079.2         128079-128335       c
            7211-7334           AC165079.2         124643-124766       c
            7335-7394           AC165079.2         123391-123450       c
            7395-7422           AC165079.2         107757-107784       c
            7423-7594           AC165079.2         106980-107151       c
            7595-7716           AC165079.2         103889-104010       c
            7717-7848           AC165079.2         102891-103022       c
            7849-8013           AC165079.2         101207-101371       c
            8014-8092           AC165079.2         99296-99374         c
            8093-8293           AC165079.2         96809-97009         c
            8294-8432           AC165079.2         91647-91785         c
            8433-15439          AC165079.2         83194-90200         c
FEATURES             Location/Qualifiers
     source          1..15439
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 24.27 cM"
     gene            1..15439
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /note="kalirin, RhoGEF kinase"
                     /db_xref="GeneID:545156"
                     /db_xref="MGI:MGI:2685385"
     exon            1..114
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     CDS             48..8996
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /EC_number="2.7.11.1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     huntingtin-associated protein interacting protein (duo);
                     serine/threonine kinase with Dbl- and pleckstrin homology
                     domains; protein Duo; serine/threonine-protein kinase with
                     Dbl- and pleckstrin homology domain"
                     /codon_start=1
                     /product="kalirin isoform 1"
                     /protein_id="NP_796331.2"
                     /db_xref="GeneID:545156"
                     /db_xref="MGI:MGI:2685385"
                     /translation="MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVA
                     FVSGGRDKRGGPILTFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRG
                     SKWDLIKPLLKTLQEAFPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLT
                     KLVDPSQLTEEFDGSLDYNHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPV
                     DVEGSRRLIDEHTQLKKKVLKAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQS
                     LVPKITSLLDKLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFL
                     QSHTEIGVSYQHALDLQTQHNHFAMNSMNAYVNINRIMSVASRLSEAGHYASQQIKQI
                     STQLDQEWKSFAAALDERSTILAMSAVFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDL
                     ELAIHHHQSLYEQVTQAYTEVSQDGKALLDVLQRPLSPGNSESLTATANYSKAVHQVL
                     DVVHEVLHHQRRLESIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGV
                     GKSLHRARALQKRHDDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYKAARHLEV
                     RIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKEVLEDVCADSVDAVQELIKQ
                     FQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPTEARDSAMSNNKTPHSSSISHI
                     ESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIEVTAELDAWNEDLLRQMND
                     FNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIMEVQASGIELICEKDLD
                     LAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVKQVLGWIRNGESMLN
                     ASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEALLQAGHYDADAIRECA
                     EKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRDEDWCGGRDKL
                     GPAAEMDHVIPLLSKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPSVASHTRGP
                     EQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQETGEYYLS
                     THTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEIRKWV
                     TTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANHEI
                     NEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHII
                     FGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLIL
                     EHAGTFFDEIQQRHGLANSISSYLIKPVQRVTKYQLLLKELLTCCEEGKGELKDGLEV
                     MLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEI
                     SLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLK
                     ASNIETKQEWIKNIREVIQERIIHLKGALKEPIQLPKTPAKLRNNSKRDGVEDGDSQG
                     DGSSQPDTISIASRTSQNTVESDKLSGGCELTVVLQDFSAGHSSELSIQVGQTVELLE
                     RPSERPGWCLVRTTERSPPQEGLVPSSALCISHSRSSVEMDCFFPLKDSYSHSSSENG
                     GKSESVAHLQSQPSLNSIHSSPGPKRSTNTLKKWLTSPVRRLNSGKADGNIKKQKKVR
                     DGRKSFDLGSPKPGDETTPQGDSADEKSKKGWGEDEPDEESHTPLPPPMKIFDNDPTQ
                     DEMSSLLAARQAPPDVPTAADLVSAIEKLVKNKLTLEGGSYRGSLKDPTGCLNEGMTP
                     PTPPRNLEEEQKAKALRGRMFVLNELVQTEKDYVKDLGIVVEGFMKRIEEKGVPEDMR
                     GKEKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLAQLFIKHERKLHIYVWYCQNKPR
                     SEYIVAEYDAYFEEVKQEINQRLTLSDFLIKPIQRITKYQLLLKDFLRYSEKAGLECS
                     DIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQQDTFYVIELDAGMQSRTK
                     ERRVFLFEQIVIFSELLRKGSLTPGYMFKRSIKMNYLVLEDNVDGDPCKFALMNRETS
                     ERVILQAANSDIQQAWVQDINQVLETQRDFLNALQSPIEYQRKERSTAVIRSQPPRVP
                     QASPRPYSSGPVGSEKPPKGSSYNPPLPPLKISTSNGSPGFDYHQPGDKFDASKQNDL
                     GGCNGTSTMTVIKDYYALKENEICVSQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGW
                     VPGSILAPLAKATAAAESSDGSIKKSCSWHTLRMRKRADVENSGKNEATGPRKPKDIL
                     GNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVLL
                     QCKACGRPKPSITWKGPDQNILDTDNSSATYTISSCDSGESTLKICNLMPQDSGIYTC
                     IAANDHGTASTSATVKVQGVPAAPNRPIAQERSCTSVILRWLPPASTGNCTISGYTVE
                     YREEGSQVWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLPSEPSEFVRLPE
                     YDAAADGATISWKENFDSAYTELNEIGRGRFSIVKKCIHKATRKDVAVKFVSKKMKKK
                     EQAAHEAALLQHLQHPQYVTLHDTYESPTSYILILELMDDGRLLDYLMNHDELMEEKV
                     AFYIRDIMEALQYLHNCRVAHLDIKPENLLIDLRIPVPRVKLIDLEDAVQISGHFHIH
                     HLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTYVMLSGVSPFLDESKEETCINVCRVD
                     FSFPHEYFCGVSNAARDFINVILQEDFRRRPTAATCLQHPWLQPHNGSYSKIPLDTSR
                     LACFIERRKHQNDVRPIPNVKSYIVNRVNQGTSLSHNP"
     exon            115..189
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            190..304
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            305..497
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            498..1010
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1133
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            1134..1325
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1457
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            1458..1688
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            1689..1811
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            1812..2003
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            2004..2212
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            2213..2387
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            2388..2583
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            2584..2750
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            2751..2870
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            2871..3062
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            3063..3212
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            3213..3327
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            3328..3443
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            3444..3566
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            3567..3749
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            3750..3868
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            3869..3935
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            3936..4045
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            4046..4115
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            4116..4205
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            4206..4298
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            4299..4410
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            4411..4601
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            4602..4703
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            4704..4846
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            4847..4949
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            4950..5193
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            5194..5477
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            5478..5582
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            5583..5675
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            5676..5806
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            5807..5873
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            5874..5977
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            5978..6047
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            6048..6134
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            6135..6227
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            6228..6278
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            6279..6356
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            6357..6542
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            6543..6714
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            6715..6953
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            6954..7210
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            7211..7334
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            7335..7394
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            7395..7422
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            7423..7594
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            7595..7716
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            7717..7848
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            7849..8013
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            8014..8092
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            8093..8293
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            8294..8432
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     exon            8433..15439
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /inference="alignment:Splign:2.1.0"
     regulatory      10499..10504
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /note="hexamer: AATATA"
     polyA_site      10525
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /note="major polyA site"
     regulatory      15420..15425
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /note="hexamer: AATATA"
     polyA_site      15439
                     /gene="Kalrn"
                     /gene_synonym="2210407G14Rik; DUET; E530005C20Rik; Gm539;
                     Hapip; TRAD"
                     /note="major polyA site"
ORIGIN      
        1 gaggctgtgc cctggagact gactgtgaag gatgagttca gggtgggatg acggaccgct
       61 tctgggacca gtggtatctt tggtatctcc gcttgcttcg gcttctggat cgaggatctt
      121 ttcggaatga tggtttgaaa gcttctgatg tccttcctat cctaaaggag aaagtggcct
      181 ttgtgtctgg ggggcgtgac aagcgaggtg gacccatcct gaccttccct gcccgaagca
      241 atcatgacag aataagacag gaagacctac ggaaacttgt gacgtatttg gccagcgtgc
      301 caagtgagga cgtttgcaaa cgtggcttca ccgtcatcat cgacatgcgg ggctccaagt
      361 gggatctcat caagcccctc ctcaagacgc tgcaggaagc cttccccgcc gagatccatg
      421 tggccctcat catcaagcct gacaacttct ggcagaagca gaagaccaac tttggcagct
      481 ccaaattcat ctttgagaca agcatggtgt ctgtggaggg cctcacgaag ctggtggacc
      541 cctcccagct gacagaggag tttgacggct ccctggatta caaccatgag gagtggattg
      601 agttgcgcct ctccctggag gagttcttca acagtgcggt ccacctgctc tcacgccttg
      661 aggacctgca ggagatgctg gcccggaagg agttccctgt ggatgtggag ggctctcgga
      721 ggcttatcga cgagcacacg caacttaaga aaaaggtgct gaaggccccc gtggaagagc
      781 tggaccggga ggggcagcgt ctactgcagt gcatccgctg cagcgatggc ttctcagggc
      841 gcaactgcat cccaggaagt gccgacttcc agagccttgt acccaagatc accagcctcc
      901 tggacaagct gcattccacc cgacaacacc tgcaccaaat gtggcacgtg cgaaagctca
      961 agctggatca gtgcttccag ctgcggctct tcgagcagga tgctgagaag atgttcgact
     1021 ggataagcca caacaaggag ttatttcttc agagccacac agagatcgga gtcagctacc
     1081 agcatgcact agacctccag acacagcaca atcactttgc catgaactcc atgaatgcct
     1141 atgtcaacat caaccgcatc atgtctgtcg cttcccgcct ctcagaggcc ggccattatg
     1201 cctcccagca aatcaagcag atctccacgc agctagacca ggagtggaag agctttgccg
     1261 ctgccctgga tgaacgcagt acaatcctgg ccatgtctgc tgtgttccac cagaaggcag
     1321 agcagttcct gtcaggcgtg gatgcctggt gtaagatgtg cagcgaaggc ggccttcctt
     1381 ctgagatgca ggacctggag ctggcaatcc accatcacca gtccttatat gagcaggtga
     1441 cccaggccta cacagaggtc agccaggatg gcaaagcact actggatgtc ctgcagcgtc
     1501 ccctgagtcc tgggaactct gagtccctca cagccacagc caactactcc aaggcggtcc
     1561 accaggtgct ggatgtggtc cacgaggtgc tgcaccatca gcgacggctc gagagcatct
     1621 ggcagcaccg caaggtgcgg cttcaccagc ggctgcagct gtgtgtcttc cagcaggatg
     1681 tgcagcaggt gctggactgg attgaaaacc atggcgaggc ctttctcagc aaacacactg
     1741 gggttggcaa gtccttgcat cgagcacgtg cactacagaa gaggcatgat gactttgaag
     1801 aagtggcaca gaatacatac accaatgcgg acaagctcct agaagcagcg gagcagctgg
     1861 ctcagactgg ggaatgtgac ccggaggaga tctacaaggc agcccggcac ctggaggtgc
     1921 gcatccaaga ctttgtgcgc agagtggagc agcggaagct gcttctggac atgtcggtct
     1981 ctttccacac gcacaccaaa gagctgtgga catggatgga ggaccttcag aaggaggtgc
     2041 tggaggatgt ctgtgcagac tctgtggatg cggtccagga gctgatcaag cagttccagc
     2101 agcagcagac cgccaccctg gatgccactc tcaatgtcat caaggaaggc gaagacctta
     2161 tccagcagct caggtcagcg cctccctccc tgggggagcc caccgaggcc agggactcag
     2221 cgatgtccaa caacaagaca ccccacagta gctctatcag ccatattgag tctgtcctcc
     2281 agcagctgga cgatgctcag gtacagatgg aagagctgtt tcacgagcgg aagatcaagc
     2341 tggacatctt cctacagctg cgcatctttg aacagtacac cattgaggtc actgcagagc
     2401 tggatgcctg gaacgaggac ttgctccggc agatgaatga tttcaacaca gaggatctga
     2461 ccctggctga gcagcggcta cagcgccaca cagaacggaa gcttgccatg aacaacatga
     2521 cgttcgaggt catccagcag ggccaggacc tgcaccagta catcatggaa gtgcaagcgt
     2581 caggaatcga gttaatctgt gagaaggacc ttgacctggc agctcaggtg caggagctgc
     2641 tggagtttct ccatgagaag cagcacgagc tggagctcaa tgcggagcag acgcacaagc
     2701 ggctagagca gtgtctccag ctgaggcacc tccaggctga ggtcaaacag gttctgggat
     2761 ggatccgcaa tggagagtcg atgctcaacg ccagcctggt caacgccagc tctttgtcgg
     2821 aggcagagca gctgcagcgg gagcatgaac agttccagct agccatcgag aagacgcacc
     2881 agagcgccct gcaggtacag cagaaggcag aggcactgct ccaggccggc cactacgacg
     2941 cagacgccat ccgggaatgt gctgagaagg tggccctcca ctggcaacag ctcatgctaa
     3001 agatggagga ccggctgaag cttgtcaacg cctctgtggc cttttacaag acctctgagc
     3061 aggtgtgcag tgttctggag agcttggagc aggagtaccg gagagacgag gactggtgtg
     3121 gtgggagaga caagctgggg ccggcggcag agatggacca cgttattcca ctcctcagca
     3181 agcacctgga gcagaaggag gccttcctga aggcctgcac gctggcaagg cggaacgccg
     3241 aggtgttcct caaatacatc cacaggaaca atgtgagcat gcctagtgtt gccagccaca
     3301 cccgggggcc tgaacagcaa gtaaaagcca tcttgagcga gctcttgcag agggagaatc
     3361 gagtcctgca cttctggacc ttgaagaagc ggcggttaga ccagtgtcag caatatgtgg
     3421 tgtttgagcg cagtgctaag caggcactgg actggatcca agaaacagga gaatattacc
     3481 tctcaacaca tacctccacc ggagagacca cggaggagac tcaggagctg ctgaaagagt
     3541 atggagaatt cagggtgcct gccaagcaaa cgaaggagaa ggtgaaactt ctgatccagc
     3601 tagcagacag ctttgtggaa aagggccaca tccacgccac agagatacgg aaatgggtga
     3661 ccacggtgga caagcactac cgcgatttct ccctgaggat ggggaagtac cggtactcgc
     3721 tggagaaggc gctgggggtc aacacggagg ataacaagga cctagagctg gacatcatcc
     3781 cagcaagcct ttcggatcgg gaggtcaagc tccgggacgc taaccatgag atcaatgaag
     3841 agaaacggaa gtcagctcga aagaaagagt tcattatggc tgaactgctc caaactgaga
     3901 aggcttatgt aagggacttg cacgagtgct tggagaccta cctgtgggag atgactagtg
     3961 gtgtggaaga gatacccccc ggcatcctca ataaggaaca tatcatcttc ggcaacatcc
     4021 aggagatcta tgacttccat aacaacatct tcctcaaaga gctggagaag tacgagcagc
     4081 tgcctgagga tgtgggacac tgctttgtta cctgggcaga caaatttcag atgtatgtca
     4141 cctactgtaa aaacaagcct gattccaacc agctgatcct ggagcatgcg ggcaccttct
     4201 ttgatgagat ccagcagcgg catggcctgg ccaactccat ctcctcctac ctaattaagc
     4261 ctgtccagag ggttaccaag taccagctgc tcctgaagga acttctaact tgctgtgaag
     4321 aagggaaagg agagctgaag gatggcctgg aggtgatgct cagtgtcccc aagaaagcca
     4381 acgatgccat gcatgtcagc atgctggaag ggttcgatga aaacttggat gtacaggggg
     4441 agttgattct ccaggatgcc tttcaagtgt gggacccaaa gtcgctgatc cggaaggggc
     4501 gggagcgcca tctgttcctc tttgagatct ccttggtgtt tagcaaagag atcaaagact
     4561 cttcaggaca cacgaaatat gtttacaaga acaagctact gacctcagag ctgggtgtga
     4621 ccgagcatgt agaaggtgac ccctgcaaat tcgccttgtg gtctgggcgc accccatcct
     4681 cagacaataa aacagtgctc aaagcttcca acatcgaaac caagcaggaa tggatcaaga
     4741 acattcgaga agtgattcag gagaggatca ttcatcttaa aggcgcttta aaggagccaa
     4801 ttcagctccc caaaacacca gccaaactga ggaacaatag taagagggat ggggtagagg
     4861 atggtgacag ccaaggggat gggagcagcc agccagatac catatccatt gcctccagga
     4921 cctctcagaa cacagtggaa agtgacaagc tctcaggtgg atgtgagctg accgtggtcc
     4981 tccaggactt cagcgcaggc cacagcagcg agctgagcat ccaggtgggc cagacggtgg
     5041 agctgctgga acgaccgagt gagaggcctg gctggtgtct ggtccgcacc acagagcgga
     5101 gccccccaca ggaaggcctg gtacccagca gcgccctgtg catctcacac tctcgcagca
     5161 gcgtggaaat ggactgcttc ttccccttga aagattcata ctctcattcc tccagtgaga
     5221 atggaggcaa atccgagtcc gtggcccacc tgcagtctca gccctccctg aactccatcc
     5281 acagttcccc tggtcccaag cgctccacca acaccctcaa aaagtggctg accagccccg
     5341 tgcgccgcct caacagcgga aaagccgacg ggaacatcaa aaagcagaag aaagtccggg
     5401 atgggcggaa gagcttcgat ctgggatcgc ccaagcctgg ggatgagacg acacctcagg
     5461 gagacagcgc tgacgagaag agcaagaagg gttggggcga agacgagcca gatgaagagt
     5521 cacacacacc cctccctccg cccatgaaga tctttgacaa cgaccccaca caggatgaga
     5581 tgtcgtcttt gctagcagcc cggcaggctc cccctgacgt gcctactgct gcagaccttg
     5641 tcagtgcaat agaaaagttg gtcaaaaata agctgactct ggaaggaggc tcttaccggg
     5701 ggagcttgaa ggaccctaca ggctgcctga atgaggggat gacccctccc acacctccta
     5761 gaaacctgga agaagaacag aaagccaagg cgctgagagg caggatgttt gtcctgaatg
     5821 agctggtaca gacagagaag gactacgtca aggacctggg gattgtggtg gagggcttca
     5881 tgaagagaat agaagagaag ggggtccctg aggacatgcg agggaaggaa aagatcgtgt
     5941 ttggaaatat ccaccagatt tacgactggc ataaagattt tttcctggct gaactggaaa
     6001 aatgtatcca agagcaagac agattggccc agctcttcat taaacacgag cggaagctgc
     6061 acatctacgt gtggtactgc cagaacaagc cgcgttccga gtacatcgtg gctgagtacg
     6121 atgcctattt tgaggaggtt aaacaagaga tcaatcaaag gctgaccctt agtgacttcc
     6181 tgatcaagcc cattcagaga ataacaaagt accagctgct actcaaggac ttcctgcgat
     6241 acagcgagaa ggctggtttg gagtgttccg atattgagaa agcagtggag ttaatgtgcc
     6301 ttgtccccaa gcgctgtaat gacatgatga atctgggacg cctgcagggc ttcgagggca
     6361 ccctgaccgc ccagggcaag ctactgcagc aggacacatt ctatgtgatc gagctggatg
     6421 ccggcatgca gtcccggacc aaggagaggc gtgtgtttct ctttgagcag attgtcatct
     6481 tcagtgaact gctccgaaag gggtccctca ccccaggcta catgttcaaa agaagcatca
     6541 agatgaatta cttggtcctg gaagacaatg tggatggtga cccctgcaaa tttgcactca
     6601 tgaacaggga gacttcagaa agggtcattc tacaggctgc caactcagac atccagcagg
     6661 cctgggtgca ggacatcaac caagtcctag aaacacagag ggacttctta aatgcactac
     6721 agtcacccat tgagtatcag cggaaggaga gaagcacagc tgtgatccgg tcccagcccc
     6781 cgagggttcc acaagccagc cccaggccct actcttctgg cccggtgggc tcagagaagc
     6841 cccccaaggg ctccagctat aacccgcctc tgccacccct gaagatatct acctctaatg
     6901 gcagtccagg gttcgactac catcagcctg gggacaagtt tgacgctagc aagcagaacg
     6961 acctgggagg ctgcaatggg acatcaacca tgactgtaat caaagattac tatgcactga
     7021 aggagaatga aatctgcgtg agccaaggtg aggtggtaca ggtcctcgcc gtcaaccagc
     7081 agaacatgtg tctggtgtac cagcctgcca gcgaccattc cccggcagca gagggctggg
     7141 tcccaggcag catcctggcg cccctcgcca aagccacagc agcggccgaa agtagtgacg
     7201 ggagcatcaa gaagtcatgc tcttggcaca ctctacgcat gagaaagcgg gcagacgtgg
     7261 agaactcggg taaaaatgaa gccacagggc ctcgtaaacc caaggatatt ctgggcaaca
     7321 aagtctctgt taaagagacg aacagttccg aggagtcaga gtgtgatgat cttgacccta
     7381 atactagtat ggagatcttg aatccaaatt tcatccagga agtggctcca gaattcctcg
     7441 tgcccttagt agatgtgacc tgtttgcttg gagacacagt gctactgcag tgtaaagcct
     7501 gtgggcggcc aaagcccagc atcacctgga agggtccgga tcagaacatc ctagacactg
     7561 acaacagttc agcaacatac accatctcct cctgtgattc tggggaaagc accctcaaga
     7621 tctgcaacct gatgccccag gatagtggga tttatacctg catagcagca aacgaccacg
     7681 ggactgcatc cacatctgct acagttaagg tgcaaggtgt ccccgcagcc cccaaccgcc
     7741 caatcgcaca ggagaggagc tgcacctccg tcatcctccg ctggctgccc ccagccagca
     7801 ccggaaactg cactatttcg gggtacacag tggagtatcg cgaggaaggt tcccaggtct
     7861 ggcagcaatc cgtagcttcg accttggaca cttacctggt cattgaagac cttagtcctg
     7921 ggtgccctta tcagttcagg gtcagtgcca gcaacccctg gggaatcagc cttcccagtg
     7981 agccctcgga gtttgtgcgc cttccagagt acgatgcagc cgccgacggt gccaccattt
     8041 cttggaagga aaattttgat tctgcttaca ctgaactgaa cgagattggc agaggccgtt
     8101 tctctattgt aaagaaatgc attcacaaag ctacccgcaa agatgttgct gtgaaatttg
     8161 tgagcaaaaa aatgaagaag aaggagcagg ctgctcacga ggccgccctg ctccagcacc
     8221 tgcagcaccc tcagtatgtc acgctccatg acacctacga gtcccccaca tcctacatcc
     8281 tgattttgga actgatggat gacggccgac tcttggacta ccttatgaat catgatgagc
     8341 tgatggaaga aaaggtagct ttctacattc gagacatcat ggaagctctg cagtacctgc
     8401 acaactgtag ggtcgcacat ttggacataa agcccgaaaa cctgctcatt gacctccgga
     8461 tcccagtgcc tcgagtgaag ctcatcgact tggaagacgc tgtccagatc tcaggccact
     8521 tccatatcca ccatctgctg gggaaccctg agttcgctgc ccccgaagtg atccaaggca
     8581 tccctgtctc cctgggcaca gacatctgga gcatcggggt tctgacatat gtcatgctta
     8641 gtggggtctc ccccttctta gatgagagca aagaggaaac ctgtatcaac gtgtgcaggg
     8701 tggactttag cttcccccac gagtacttct gcggtgtgag caatgctgcc agggatttca
     8761 tcaacgtaat cttacaggaa gacttccgga ggcggcccac agcagccacg tgcctgcagc
     8821 atccctggct acagccccac aacggcagct actccaagat ccccttggac acctcccgtc
     8881 tggcctgctt catagaacgc cgcaagcacc agaatgatgt gcggcccatt cccaatgtca
     8941 agagttacat cgtcaatagg gtgaaccaag ggacctcgct atcccacaac ccctgaggtt
     9001 tcacatagta gtgcagtgtg aaccaaagca agactgagcg tgtctgtaaa taactctgat
     9061 catcatttca ctccatgtgg ttctctggac tgacaggtga tcctcttaaa ccttgtctgt
     9121 ggttacccgg ggtctgagta ccatgaaagt caccttaatc ccagaaggtc atgctgaaga
     9181 agtaaagata cagagttgca gaaagtatta aaagaaaggg caaggctaag gagacagtac
     9241 ttggtatgaa aatggtaatt gtacattcca aaatgagcag ttaagtggga aaaccgtaca
     9301 cccactgtga gcagtatggt aggtttctga ctccattgaa aatttaagca aaaacaaaaa
     9361 aacaaaaaaa acaaaaacaa aaaaaagttc tatttaacag agatgtcaac tattctgctt
     9421 tagatggctt agatatagtt tcttaacagg atacatatac gcatacaata taatagatct
     9481 cattcaggtt tcagagtttt ataatataga gttctatatg aaatctatca taagtaactt
     9541 tgagtgctcc cattaagaca gtaatttctt taccgaagca ttgcattatt ttgactaagc
     9601 acaattagat gacaagtttt ttagagcatt ttataaatct tgtatagaaa tcttttatca
     9661 gaacctgtgt attaagagaa agcaatgtga cccttttgcg atctgtgact gggatatttt
     9721 tccctccatc atgggttgta tgactaagat aggttctgta gatcaaagct ttccctgccc
     9781 tgaactcatg ggcagctcag agttcctcct gtgggaaaga ctgccaggaa ataaatccaa
     9841 atctagtaag agttggcggg tgggggttgt ttttatgtcc accctaggcc tgccataggc
     9901 aaatgaatat cacaagttca tacaggaggg cacacggaag cttttcctac agttcctgtg
     9961 aacagcgtag cagcgctttc tgatttcata gctgtagaat acagttttca gaaagttagc
    10021 ttgctttatt cctaacccct cgtgaagctt cggggtgctt accaaaagga ggcagccata
    10081 aaagcctttt aaaggctagt cctaagtcct tcctgaagcc atggagcaaa gcctgaccca
    10141 tcactctaac acagcacggg gttttaactg tggtagcaat acctatcacc acacagccac
    10201 caacggctct ggacagaaag gaccaattgt attctgaggc cagtgccgct ttctcataca
    10261 agattatgcc cagtgccctc tggagggaaa acacattaac cagggcactt catgtttttt
    10321 tgttttgtta tgttttgttg gttttttggt ttttacttct tctgttggaa ggggggtggg
    10381 ggaggtttgg ttttttgctt tgttttttta aaaattattt tctgtttgta catgatccac
    10441 cctttgtttc ctagagtgtg ctttaaaaat cgctttgaag caaataatat tcttaaaaaa
    10501 tatataactg aaatgtttgt gtaaaccggg tttcatgtca tcgtgtcgct cctgctagtg
    10561 ggaactgaga aaatggaagt tatgtagcac aaagtgcaat cagagaatct gggaagggaa
    10621 aatggaactg cataactatt taaactattt aaaggagaca tgatgggaac agtctaattt
    10681 taaggtataa aaccacttat tcccatggtg gaactataga attaaaatac tcatcaccac
    10741 ctccccccgc cccgtcagtt tcaaagtcag attactcatc atccatcctc catcccagct
    10801 tatccgagat gatagggaaa taaactagta ggaagtaaaa gcaataaagc tagatagcac
    10861 ctagtattgt ggggattaac caaatacgtg ggaaccgact ctgactgtat tctccttgtc
    10921 tccgggtggc cctgggtcat caggcctcac tccctcagag cttgcttacc tccatggttt
    10981 tcacttaaac cacaatgcat gcccaaagca tgcttactga agctttttaa aataaacgtg
    11041 tctttattaa gaaatgtagc attgaggagg aaggcctggg gccagagggc ttattctagg
    11101 ataaaatgca ggctctgagg actccaaaga tccacaaagt gacatggcca ggtctgttct
    11161 gtccacttgt ccactctggc tgtcttgaaa gaagggcttc ctgctgagtt acttagaatt
    11221 gttctgaccg gtcaagtttt gactagagag ggacacagag cctaagactg gtgttcagac
    11281 gctacagaag ggccacattg aaaggatgta gtgcgtggta gaactctata gagagccaag
    11341 ttttcccagc catgtttgtg tcagagttgg aatggtctag atatggggct atgtggaatt
    11401 gccccaggta cacagtacaa ctgttaagag tagtgtaagc ttcagggacg tacaaagaga
    11461 aaggggcatt ctctgtatag tttgatgact gaagtgaaca gggaggcccc tgtctacaaa
    11521 gcacctgatc cctccaaata gggggcaaga gagtcttggc tggagacttt tccctagcaa
    11581 ggtgggaatt agtaagagaa acaccattga cagggctagg aaatagagtt tggagtacaa
    11641 ctgtgctcca cagtggctgg agaagaagac ccaccccaag accactctcc tgtacctgtg
    11701 ttggcaggga gacttagaac taggagagaa aggtggggag gggagaaaaa tctcccactc
    11761 cgaaccccat cccaattgtt cttgctgaga gtgagctgtc agctgacccc aggagagcaa
    11821 cagtgctggc gaaagatttc ttatttggtt tctactcatc attttgagct catttgtttt
    11881 gtgttcaaag ggtggggtac agaaagatgg aaacgatcag ggacagccca ggatccctga
    11941 tgagaactca tgattttttg cgccatttat gtttgtttcg aattaaacag atttctaccc
    12001 acttataaca gaatgtggtt aaaaactgtt aagaaagaaa acaacaaaac acaaaacaaa
    12061 caaacaaaca aacaaacatg gcaatgttgg atgtgtcctt caggtctctc ccagccacca
    12121 gcagcctaag tgggtagagg aggcagaggg gaaagctggc tttggctttg tgcttaacga
    12181 agcctttata aacagtagtg cctttcagag gggaggtgga gagtgaagtt agattgcgtt
    12241 tagatttgct gatactgcgg tctttttttc cccttaggtt taagctatgt tttaaatgag
    12301 aatatctgaa tgtaggatgg gaacaggaat ttttgagtct ccatctcagc tattccaaac
    12361 ccagtctttc ttccaggaag tcttttgttg ttttctggcc caaatgtctc cattgataaa
    12421 atggaatttg gggagaagag gagagaacat taatctctta agaatgttga gaaaaatatc
    12481 cttgtcgaca catctataag atgttttgat tttcttcaag tgctacacac tgccagtgtt
    12541 tagaatttta tcgacagcaa ctttgaacat tccagtttcc cacagtctta tctttgggta
    12601 ccgtttacaa actcatgagg ttgacctctg taaattgctt ctcactggaa ggtctgggtc
    12661 cttctcatct acatgttaat tgttcttacc ttttaatttc taacctctaa gagcttctct
    12721 acagagcagg gtttgggaga actgaggagg cctaaaatgt ccataagctg ttttccacag
    12781 tattcttagg gtggacatga gtctgatgcc taccaagaca gagaaccatt tctttctctt
    12841 accaagcttt atgctggggg cagggggagg acaaagaaga atccaaatag ctactttcca
    12901 cactggaagg acagatgtga gaatcgaata cacttcctag gctccctcgt cacaattcat
    12961 ttccttagag acccacagga atcttttaga aaaggcaagt gatgcccaca gtgggaaaga
    13021 gaattagatt ttggagaaag agagctttgg ctttgctctt cgagggtcgt cttctgttgt
    13081 ctccaaaccc ccatgcccat gacccactca tccttccttc cttcttgctt atcttgaaaa
    13141 acatggcaag ttagattttt gagaatatga tggagaaaat gccatctaaa gaaaatggtg
    13201 gttatttttc agtgttaata gaaactctct cctctatacc tgatagaggg aaatacattg
    13261 aacacaaagg gtctctgtag tagacaaaag aacacaatca ccacacccta ggatagccca
    13321 tcaattgcac tgggtgagtt ttgaggaact tagaccatat tcttttcttg cctgggtaac
    13381 attccattgg agtctgagtt aggcaaacat atataagctt tcaatagatt tatctgttaa
    13441 agaaaaataa acctaatgat ttttgtttgc tatttgaaat ctaaagacct ttagggaagg
    13501 aagttattag acctagaata ggctaaagga aatgctcaca tagattccac caacaggaaa
    13561 gaagatgcta tgttagtaat tattttctga gaatggtaag gctctcactg tctcattcat
    13621 tttaaagagc tcaaaggggc tgaaatttat ccatagacat atttttttta aataggaaat
    13681 gtttttcatg aaaaatccat atggaaattg aatacagaat tatcatatga tcatatttgt
    13741 tataaaagac atttttctct tattttttaa atataagttg acattatagg agaagaaaac
    13801 ggtcattcca ctacaatgct ttaatcttaa atgacattaa ttaaaagcct aaaattaaca
    13861 ctcccaggct attgtcaaga acttccatgc tgtggtcaga tttcattttt atctgaatga
    13921 ccaacccaac agttcacaag gggggagcgc aaggaaaggt ttagatagca agtcttggaa
    13981 ctcctgagtg ttaatttaac caagtagatc tgccagtgca gggataggag ctgcattaat
    14041 cccccatttc catcaataac taagtccgca tgtcggagtc catgaagacc gttactgtga
    14101 cctcaaagac tgtggctacg aatctcaagt cttctcttac taacttaagc catatctttc
    14161 acctctgtgt ttgaattttt ttttttttaa atcaaaaccc tggtgctttt acttctgttt
    14221 ctgctgaacg ttagacgact ctgtgggaaa gtcaataaaa ctagaagagg aataaataga
    14281 aagactgtga aaaactaacc atacccttga gaaaatgcta tttatgcaga gaacagtggc
    14341 aatggagggc aaactgttgg aaaatattga tatatgtaca tctgagcatg tatatagtgt
    14401 ataatatgta tgtatatgtt attgctcata tgcagaaatc tatccatttt tcaggcagcc
    14461 caggtgggtc agtttttcta ctggaaaacc atttaggacc attcaaaacc attagggata
    14521 atacatggag aattctcgtc acatgggagt tgatttgttg acttctgaag tccacatggc
    14581 caaatgaaca aagtatgaaa tgcattgaga ctataattta tgtgactctg tttactcaga
    14641 agtctatatt tgaattcttt tgtatgtgtg tatgtttgga tttttttgtt tgtttgtttt
    14701 tgatgagaca gggtccctct atgtagttgt ggctgtcctg ggactcattc tatagaccag
    14761 gctggccttg aactcacaga ggtctgcctg cctctgcctc ctgagtgctg ggattaaagg
    14821 catgtgccat caggtccagc caatatttga attttaatat ctgattttca aactgcacca
    14881 acacttcttg gttttgagtg atcccttccc caaagccttt tgagaatttg tggtgggcat
    14941 ctctggccaa tctgtaaaag gccttatcaa taagtggaca ggtttcccca tagggaccat
    15001 tacacatata catataagta catacttcca tcaggcttgt gacaattgtt ttaaaatcac
    15061 tccacagtat tggtaaatag ctctatattt tcaaggtgca gaagaattcc acagccttaa
    15121 ttatttcagt gtcttgctgg tctgccttaa tgtatcttct ggggtttttg ggttttggtt
    15181 gtcttattat tttaactttt tctgcagctg ttcattttgt atgcacatga tgttgttttg
    15241 taaaggtagg ttgtaaatat tttatttgta agtctgactc actcactcac tcactcactc
    15301 actcactcct gtgtaatgtt gtaaagtgcc gacctgctgt cttgttctta ttgcagtaaa
    15361 cgttataagt tgtggatgaa acttcaaaat gtacatttca catgttatgc attcctataa
    15421 atataatata ctgaaggta
//
