LOCUS       NM_206924               1103 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus jumping translocation breakpoint (Jtb), mRNA.
ACCESSION   NM_206924 XM_130925 XM_181436
VERSION     NM_206924.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1103)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1103)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 1103)
  AUTHORS   Hald,J., Galbo,T., Rescan,C., Radzikowski,L., Sprinkel,A.E.,
            Heimberg,H., Ahnfelt-Ronne,J., Jensen,J., Scharfmann,R.,
            Gradwohl,G., Kaestner,K.H., Stoeckert,C. Jr., Jensen,J.N. and
            Madsen,O.D.
  TITLE     Pancreatic islet and progenitor cell surface markers with cell
            sorting potential
  JOURNAL   Diabetologia 55 (1), 154-165 (2012)
   PUBMED   21947380
REFERENCE   4  (bases 1 to 1103)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   5  (bases 1 to 1103)
  AUTHORS   Kanome,T., Itoh,N., Ishikawa,F., Mori,K., Kim-Kaneyama,J.R.,
            Nose,K. and Shibanuma,M.
  TITLE     Characterization of Jumping translocation breakpoint (JTB) gene
            product isolated as a TGF-beta1-inducible clone involved in
            regulation of mitochondrial function, cell growth and cell death
  JOURNAL   Oncogene 26 (41), 5991-6001 (2007)
   PUBMED   17369841
REFERENCE   6  (bases 1 to 1103)
  AUTHORS   Hatakeyama,S., Osawa,M., Omine,M. and Ishikawa,F.
  TITLE     JTB: a novel membrane protein gene at 1q21 rearranged in a jumping
            translocation
  JOURNAL   Oncogene 18 (12), 2085-2090 (1999)
   PUBMED   10321732
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY308991.1, AK004469.1, BG077727.2 and BY617278.1.
            
            On Feb 2, 2007 this sequence version replaced NM_206924.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK146337.1, SRR1660813.306216.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-89                BY308991.1         2-90
            90-593              AK004469.1         2-505
            594-711             BG077727.2         160-277
            712-1100            AK004469.1         624-1012
            1101-1103           BY617278.1         410-412
FEATURES             Location/Qualifiers
     source          1..1103
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 39.21 cM"
     gene            1..1103
                     /gene="Jtb"
                     /gene_synonym="Gm622"
                     /note="jumping translocation breakpoint"
                     /db_xref="GeneID:23922"
                     /db_xref="MGI:MGI:1346082"
     exon            1..444
                     /gene="Jtb"
                     /gene_synonym="Gm622"
                     /inference="alignment:Splign:2.1.0"
     CDS             362..802
                     /gene="Jtb"
                     /gene_synonym="Gm622"
                     /note="protein JTB"
                     /codon_start=1
                     /product="protein JTB precursor"
                     /protein_id="NP_996807.1"
                     /db_xref="CCDS:CCDS17523.1"
                     /db_xref="GeneID:23922"
                     /db_xref="MGI:MGI:1346082"
                     /translation="MLAGAGRRGLPRAGHLCWLLCAFTLKLCEAEAPVREEKLSVSTS
                     TSPCWLAEEFVVTEECTPCSNFQIKTTPECGSTGYVEKITCSSSKRNEFKSCRSALLE
                     QHLFWKFEGVVVAVALVFACLVIVRQRQLDRKALEKVRKQIESI"
     exon            445..482
                     /gene="Jtb"
                     /gene_synonym="Gm622"
                     /inference="alignment:Splign:2.1.0"
     exon            483..565
                     /gene="Jtb"
                     /gene_synonym="Gm622"
                     /inference="alignment:Splign:2.1.0"
     exon            566..645
                     /gene="Jtb"
                     /gene_synonym="Gm622"
                     /inference="alignment:Splign:2.1.0"
     exon            646..1103
                     /gene="Jtb"
                     /gene_synonym="Gm622"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1083..1088
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Jtb"
                     /gene_synonym="Gm622"
                     /note="hexamer: AATAAA"
     polyA_site      1101
                     /gene="Jtb"
                     /gene_synonym="Gm622"
                     /note="major polyA site"
ORIGIN      
        1 gagatgcagt tgccaccgag tccggaacga caacagcagc aaacagacga gagcacccgg
       61 gaagagtcgg cgtcgccagt gccgggacca ggagcctccg cgagcaagat ggccgctccc
      121 gagaccgagg ccgaggggca cgggcactag gtccggaccc gcgtacccct ttcccggacg
      181 cctgcgtccc cacaaagacc tcgtgcttct agcaagacac ccgcatggat tattctcgct
      241 gtggtcacga ggccgttcct atagcgctct agttggccca gactgagaac tctggcatct
      301 ggctgctcgg agctggaacc tcagggaggt ctgctgcaac aggtgcgacc ctgaccgctc
      361 catgctcgcg ggcgcgggga ggcgtggcct cccccgggcc ggccacctct gttggctgct
      421 gtgcgctttc accttaaaac tctgcgaggc agaggctccg gtgcgcgagg agaagctatc
      481 agtgagcact tcaacttcgc catgttggtt ggcagaagag tttgtggtga ctgaagagtg
      541 tactccgtgt tctaacttcc agattaaaac aacacctgag tgtggttcta cagggtatgt
      601 ggaaaaaatc acatgcagct catctaagag gaatgaattc aaaagctgcc gttcggctct
      661 actggaacaa cacttattct ggaaatttga aggcgttgtg gtggctgtag ctttagtctt
      721 cgcctgcctt gtcatcgttc gtcagcgaca actggacaga aaggctcttg aaaaagtcag
      781 gaagcaaatt gagtccatat agctgaattt ctactgtatt atggtggctc tttacggact
      841 gtatctcaga tggagaaagt tcagcggcta atttgcactc gtaaacctgt ggtagtagca
      901 ttttcaatga cttcctcttc tagaccatta atgagcacaa taaaaagtaa aatagagctg
      961 gacatgacac agacttggaa tcccagcact tgagagaatg aggcaggagg atccttggta
     1021 actttgtagg ccgactaggc tgaactacat agtaagcctg tctttaaaga gaaaacggaa
     1081 ataataaagg agtaaagagt ttc
//
