LOCUS       NM_008258               1389 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus Jupiter microtubule associated homolog 1 (Jpt1), mRNA.
ACCESSION   NM_008258
VERSION     NM_008258.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1389)
  AUTHORS   Hupe,M., Li,M.X., Gertow Gillner,K., Adams,R.H. and Stenman,J.M.
  TITLE     Evaluation of TRAP-sequencing technology with a versatile
            conditional mouse model
  JOURNAL   Nucleic Acids Res 42 (2), e14 (2014)
   PUBMED   24165879
REFERENCE   3  (bases 1 to 1389)
  AUTHORS   Laughlin,K.M., Luo,D., Liu,C., Shaw,G., Warrington,K.H. Jr.,
            Qiu,J., Yachnis,A.T. and Harrison,J.K.
  TITLE     Hematopoietic- and neurologic-expressed sequence 1 expression in
            the murine GL261 and high-grade human gliomas
  JOURNAL   Pathol Oncol Res 15 (3), 437-444 (2009)
   PUBMED   19145478
  REMARK    GeneRIF: These data suggest a role for Hn1 in the biology of
            malignant brain tumors.
REFERENCE   4  (bases 1 to 1389)
  AUTHORS   Laughlin,K.M., Luo,D., Liu,C., Shaw,G., Warrington,K.H. Jr.,
            Law,B.K. and Harrison,J.K.
  TITLE     Hematopoietic- and neurologic-expressed sequence 1 (Hn1) depletion
            in B16.F10 melanoma cells promotes a differentiated phenotype that
            includes increased melanogenesis and cell cycle arrest
  JOURNAL   Differentiation 78 (1), 35-44 (2009)
   PUBMED   19427096
  REMARK    GeneRIF: Hn1 depletion in B16.F10 melanoma cells promotes a
            differentiated phenotype that includes increased melanogenesis and
            cell cycle arrest.
REFERENCE   5  (bases 1 to 1389)
  AUTHORS   Sone,M., Hayashi,T., Tarui,H., Agata,K., Takeichi,M. and
            Nakagawa,S.
  TITLE     The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear
            domain in a subset of neurons
  JOURNAL   J Cell Sci 120 (Pt 15), 2498-2506 (2007)
   PUBMED   17623775
REFERENCE   6  (bases 1 to 1389)
  AUTHORS   Shu,H., Chen,S., Bi,Q., Mumby,M. and Brekken,D.L.
  TITLE     Identification of phosphoproteins and their phosphorylation sites
            in the WEHI-231 B lymphoma cell line
  JOURNAL   Mol Cell Proteomics 3 (3), 279-286 (2004)
   PUBMED   14729942
REFERENCE   7  (bases 1 to 1389)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 1389)
  AUTHORS   Onodera,K., Shavit,J.A., Motohashi,H., Katsuoka,F., Akasaka,J.E.,
            Engel,J.D. and Yamamoto,M.
  TITLE     Characterization of the murine mafF gene
  JOURNAL   J Biol Chem 274 (30), 21162-21169 (1999)
   PUBMED   10409670
REFERENCE   9  (bases 1 to 1389)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   10 (bases 1 to 1389)
  AUTHORS   Tang,W., Lai,Y.H., Han,X.D., Wong,P.M., Peters,L.L. and Chui,D.H.
  TITLE     Murine Hn1 on chromosome 11 is expressed in hemopoietic and brain
            tissues
  JOURNAL   Mamm Genome 8 (9), 695-696 (1997)
   PUBMED   9271675
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645470.20.
            
            On Feb 15, 2018 this sequence version replaced NM_008258.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U90123.1, BC003758.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-174               AL645470.20        110431-110604
            175-317             AL645470.20        121650-121792
            318-415             AL645470.20        122722-122819
            416-434             AL645470.20        124140-124158
            435-1389            AL645470.20        126525-127479
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 80.84 cM"
     gene            1..1389
                     /gene="Jpt1"
                     /gene_synonym="Hn1"
                     /note="Jupiter microtubule associated homolog 1"
                     /db_xref="GeneID:15374"
                     /db_xref="MGI:MGI:1096361"
     exon            1..174
                     /gene="Jpt1"
                     /gene_synonym="Hn1"
                     /inference="alignment:Splign:2.1.0"
     exon            175..317
                     /gene="Jpt1"
                     /gene_synonym="Hn1"
                     /inference="alignment:Splign:2.1.0"
     exon            318..415
                     /gene="Jpt1"
                     /gene_synonym="Hn1"
                     /inference="alignment:Splign:2.1.0"
     exon            416..434
                     /gene="Jpt1"
                     /gene_synonym="Hn1"
                     /inference="alignment:Splign:2.1.0"
     exon            435..1389
                     /gene="Jpt1"
                     /gene_synonym="Hn1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      684..689
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Jpt1"
                     /gene_synonym="Hn1"
                     /note="hexamer: ATTAAA"
     polyA_site      703
                     /gene="Jpt1"
                     /gene_synonym="Hn1"
                     /note="major polyA site"
     regulatory      1358..1363
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Jpt1"
                     /gene_synonym="Hn1"
                     /note="hexamer: AGTAAA"
     polyA_site      1381
                     /gene="Jpt1"
                     /gene_synonym="Hn1"
ORIGIN      
        1 ccccgcggcg gtagaagctc gtggagccct ggtggtttag cttttggagt cgtctgcgcc
       61 tgttggtccc agtccccctt ggcgttttca gggccagcct acctcgcccc ttggcgccat
      121 gaccactacc actaccttta agggtgtgga ccctaacagc aggaacagct cccgggtttt
      181 gcggcctcca ggtggtgggt ccaatttttc attaggcttt gatgagccag cagaacagcc
      241 tgtgaggaag aacaagatgg cttctaacat ctttgggaca ccggaagaga accccccatc
      301 ttgggccaag tcagcaggtt ccaagtctag tggtggcagg gaagattcgg agtcgcctgg
      361 aacacagaga agtaactctt ctgaagcaag ctctggagat ttcttagacc tcaagggaga
      421 aggtgatatg catgaaaatg tggacacaga cttccaagcc aacctggcgc agatggagga
      481 gaagccagtg cccgctgctc ctgtgcccag cccagtggct ccagccccag tgccatccag
      541 gagaaacccc cctggcggca agtccagcct ggtcttgggt tagcttcttg tgttggaact
      601 ctgtccttct gtctgtctgt ttgttgtccc atgcttggga actgcacagc gtgagctgac
      661 tgtacatctc tcggattggt ttcattaaag gagaagcact ttatgtaccg ctgtctttcc
      721 ctgcttcctc tcttcctttc cttctgtctg tctgactcct gggtctgtgc gccatggcat
      781 gagtgttttc tagtagtaga ctggagtagt agactgtttc taagaacaga tgatctggtt
      841 cctgatgtgt agagactctt atgtaccagg gtttttgacg atgtccttgg cttcatgtga
      901 tgggaccgac agcagcctca ggcactaccc tgctcccagc tccacagggt gggcaccact
      961 cagcttgcct tgcacttgcc ccaccatcgg tgccctttgc taagtgcacc ttcctgtgcc
     1021 atgtggagtg atcaaacagc tgtacctcac atcctgctgc ctgcagagca gacaagctgc
     1081 cttctgtacc ctgaagatgc cattggccac tgtggctggc cagctgcggg gcagagccac
     1141 ccagcgcaga ggatggcttc aggtacacaa gcaagctccc tggaattgca aggtgaagca
     1201 cacaggaagg ccgtccgtcc cagagtggga ctgtgggcgc agctcccaca gggacctcct
     1261 tgacggaaga agtgccatgt gcatgatgct gatgcctgac catggagaaa gtctcaccct
     1321 tgacacttgt actccttagt cctggactgt tgcttaaagt aaacaatacc caccttttga
     1381 agcaccgtg
//
