LOCUS       NM_021310               8780 bp    mRNA    linear   ROD 08-AUG-2024
DEFINITION  Mus musculus junction-mediating and regulatory protein (Jmy), mRNA.
ACCESSION   NM_021310 XM_973526
VERSION     NM_021310.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8780)
  AUTHORS   Liu,Y., Fan,J., Yan,Y., Dang,X., Zhao,R., Xu,Y. and Ding,Z.
  TITLE     JMY expression by Sertoli cells contributes to mediating
            spermatogenesis in mice
  JOURNAL   FEBS J 287 (24), 5478-5497 (2020)
   PUBMED   32279424
  REMARK    GeneRIF: JMY expression by Sertoli cells contributes to mediating
            spermatogenesis in mice.
REFERENCE   2  (bases 1 to 8780)
  AUTHORS   Kluge,F., Weissbach,J., Weber,A., Stradal,T. and Posern,G.
  TITLE     Regulation of MRTF-A by JMY via a nucleation-independent mechanism
  JOURNAL   Cell Commun Signal 16 (1), 86 (2018)
   PUBMED   30463620
  REMARK    GeneRIF: JMY activates MRTF-SRF independently of F-actin via
            WH2/V-mediated competition with the RPEL region for G-actin binding
            in the cytoplasm
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8780)
  AUTHORS   Gong,W., Gohla,R.M., Bowlin,K.M., Koyano-Nakagawa,N., Garry,D.J.
            and Shi,X.
  TITLE     Kelch Repeat and BTB Domain Containing Protein 5 (Kbtbd5) Regulates
            Skeletal Muscle Myogenesis through the E2F1-DP1 Complex
  JOURNAL   J Biol Chem 290 (24), 15350-15361 (2015)
   PUBMED   25940086
REFERENCE   4  (bases 1 to 8780)
  AUTHORS   Schluter,K., Waschbusch,D., Anft,M., Hugging,D., Kind,S.,
            Hanisch,J., Lakisic,G., Gautreau,A., Barnekow,A. and Stradal,T.E.
  TITLE     JMY is involved in anterograde vesicle trafficking from the
            trans-Golgi network
  JOURNAL   Eur J Cell Biol 93 (5-6), 194-204 (2014)
   PUBMED   25015719
  REMARK    GeneRIF: JMY drives vesicular trafficking in the trans-Golgi region
            and at ER-membrane contact sites, distinct from other Arp2/3
            activators involved in vesicle transport processes such as the
            related WHAMM or WASH.
REFERENCE   5  (bases 1 to 8780)
  AUTHORS   Wang,Q.C., Liu,J., Wang,F., Duan,X., Dai,X.X., Wang,T., Liu,H.L.,
            Cui,X.S., Sun,S.C. and Kim,N.H.
  TITLE     Role of nucleation-promoting factors in mouse early embryo
            development
  JOURNAL   Microsc Microanal 19 (3), 559-564 (2013)
   PUBMED   23552571
  REMARK    GeneRIF: Results of the present study show that the
            nucleation-promoting factors JMY and WAVE2 are critical for
            cytokinesis during development of mouse embryos.
REFERENCE   6  (bases 1 to 8780)
  AUTHORS   Sun,S.C., Sun,Q.Y. and Kim,N.H.
  TITLE     JMY is required for asymmetric division and cytokinesis in mouse
            oocytes
  JOURNAL   Mol Hum Reprod 17 (5), 296-304 (2011)
   PUBMED   21266449
  REMARK    GeneRIF: JMY is required for spindle migration, asymmetric division
            and cytokinesis during mouse oocyte maturation.
REFERENCE   7  (bases 1 to 8780)
  AUTHORS   Zuchero,J.B., Coutts,A.S., Quinlan,M.E., Thangue,N.B. and
            Mullins,R.D.
  TITLE     p53-cofactor JMY is a multifunctional actin nucleation factor
  JOURNAL   Nat Cell Biol 11 (4), 451-459 (2009)
   PUBMED   19287377
REFERENCE   8  (bases 1 to 8780)
  AUTHORS   Coutts,A.S., Boulahbel,H., Graham,A. and La Thangue,N.B.
  TITLE     Mdm2 targets the p53 transcription cofactor JMY for degradation
  JOURNAL   EMBO Rep 8 (1), 84-90 (2007)
   PUBMED   17170761
  REMARK    GeneRIF: These results define a new functional relationship between
            the p53 cofactor JMY and Mdm2, and indicate that transcription
            cofactors that facilitate p53 activity are important targets for
            Mdm2 in suppressing the p53 response.
REFERENCE   9  (bases 1 to 8780)
  AUTHORS   Demonacos,C., Krstic-Demonacos,M. and La Thangue,N.B.
  TITLE     A TPR motif cofactor contributes to p300 activity in the p53
            response
  JOURNAL   Mol Cell 8 (1), 71-84 (2001)
   PUBMED   11511361
REFERENCE   10 (bases 1 to 8780)
  AUTHORS   Shikama,N., Lee,C.W., France,S., Delavaine,L., Lyon,J.,
            Krstic-Demonacos,M. and La Thangue,N.B.
  TITLE     A novel cofactor for p300 that regulates the p53 response
  JOURNAL   Mol Cell 4 (3), 365-376 (1999)
   PUBMED   10518217
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK141957.1, BC090835.1 and AC154231.2.
            
            On Mar 23, 2011 this sequence version replaced NM_021310.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC090835.1, AF201390.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-119               AK141957.1         2-120
            120-4675            BC090835.1         1-4556
            4676-8780           AC154231.2         84271-88375         c
FEATURES             Location/Qualifiers
     source          1..8780
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 47.85 cM"
     gene            1..8780
                     /gene="Jmy"
                     /note="junction-mediating and regulatory protein"
                     /db_xref="GeneID:57748"
                     /db_xref="MGI:MGI:1913096"
     exon            1..1507
                     /gene="Jmy"
                     /inference="alignment:Splign:2.1.0"
     CDS             503..3454
                     /gene="Jmy"
                     /note="p300 transcriptional cofactor JMY"
                     /codon_start=1
                     /product="junction-mediating and -regulatory protein"
                     /protein_id="NP_067285.2"
                     /db_xref="CCDS:CCDS26688.1"
                     /db_xref="GeneID:57748"
                     /db_xref="MGI:MGI:1913096"
                     /translation="MSFALEETLESDWVAVRPHVFDEREKHKFVFIVAWNEIEGKFAI
                     TCHNRTAQRQRSGSREQAGTPASDGSRGPGSPAARGRSEAAASATAALRSPGPRKSQA
                     WAEGGSPRSARSLKGDPPRGPAGRGPESPLRSPARAKASPLRRSAESRDATASATPAP
                     PAPPVPPVSSVRVVSASGAVSEEIEVLEMVREDEAPQPLPDSEQPPSAAELESPAEEC
                     SWAGLFSFQDLRAVHQQLCSVNSQLEPCLPVFPEEPSGMWTVLFGGAPEMTEQEIDAL
                     CYQLQVYLGHGLDTCGWKILSQVLFTETDDPEEYYESLSELRQKGYEEVLQRARRRIQ
                     ELLDKHKTIESMVELLDLYQMEDEAYSSLAEATTELYQYLLQPFRDMRELAMLRRQQI
                     KISMENDYLGPRRIESLQKEDADWQRKAHMAVLSIQDLTVKYFEITAKAQKAVYDRMR
                     ADQKKFGKASWAAAAERMEKLQYAVSKETLQMMRAKEICLEQKKHALKEEMQSLQGGT
                     EAIARLDQLESDYYDLQLQLYEVQFEILKCEELLLTAQLESIKRLISEKRDEVVYYDT
                     YESMEAMLEKEEMAASVHAQREELQKLQQKARQLEARRGRVSAKKAYLRNKKEICIAK
                     HHEKFQQRFQSEDEYRAHHTIQIKRDKLHDEEERKSAWVSQERQRTLDRLRTFKQRYP
                     GQVILKSTRLRVAHSRRKSTASPVPCEEQCHSLPTVLQGQEKTEVGGGGSQLGPSQTA
                     EPQSLVQLEDTSSEQLESTSLPPRAVVSSELPPPQSAPLLTSIDPKPCSVTIDPLPPP
                     LPPTPPPPPPPPPPPPPPLPVAKDNGASTTAETLEKDALRTEGNERSIPKSASAPAAH
                     LFDSSQLVSARKKLRKTVEGLQRRRVSSPMDEVLASLKRGSFHLKKVEQRTLPPFPDE
                     DDSNNILAQIRKGVKLKKVQKEVLRESFTLLPDTDPLTRSIHEALRRIKEASPESEDE
                     EEALPCTDWEN"
     exon            1508..1681
                     /gene="Jmy"
                     /inference="alignment:Splign:2.1.0"
     exon            1682..1832
                     /gene="Jmy"
                     /inference="alignment:Splign:2.1.0"
     exon            1833..2002
                     /gene="Jmy"
                     /inference="alignment:Splign:2.1.0"
     exon            2003..2168
                     /gene="Jmy"
                     /inference="alignment:Splign:2.1.0"
     exon            2169..2356
                     /gene="Jmy"
                     /inference="alignment:Splign:2.1.0"
     exon            2357..2443
                     /gene="Jmy"
                     /inference="alignment:Splign:2.1.0"
     exon            2444..2539
                     /gene="Jmy"
                     /inference="alignment:Splign:2.1.0"
     exon            2540..3146
                     /gene="Jmy"
                     /inference="alignment:Splign:2.1.0"
     exon            3147..3457
                     /gene="Jmy"
                     /inference="alignment:Splign:2.1.0"
     exon            3458..8780
                     /gene="Jmy"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8756..8761
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Jmy"
                     /note="hexamer: AATAAA"
     polyA_site      8780
                     /gene="Jmy"
                     /note="major polyA site"
ORIGIN      
        1 gccgccgccg cgtcagcagc gtgccgcacg tgcccgtgtt tacgtccctc gtggagccgc
       61 agacgtcaca gccgaatggc aacattgtgg cgacgctgag actagcgctt taggagtctg
      121 ctttctggtt ctggttctgg ctggctgggc gctgttggcc gggggcagag gggcggcggg
      181 gaggtaggcc ccggcgggcg agcggcggac gcgcgcctca gcacgcagcc ccgcggctcc
      241 gcgcaggccg gtccggcggc ccagggccct gcgctgcggc agcgagcggc ttgtaaacag
      301 atccggccgc acgtgaccat gtgaactacc tgctccgggc cgcgtattgt ctcttctgag
      361 agccgcacca caaaggagcc ggtgggtgag cggccggcgc gctaagatgg ctgcaggcgc
      421 cccgcaaggg tgagctgggg gcgcggccac cgcggagact cggccgggcg ggcgaccccc
      481 ctcgccgggc accggagcta ccatgtcgtt cgcgctggag gagacactcg agtccgactg
      541 ggtggcggtg cggccccacg tattcgacga gcgcgagaag cacaagtttg tgttcattgt
      601 ggcctggaac gagatcgaag gcaagtttgc tataacctgt cacaaccgga cggcccagag
      661 acagaggagc ggttcccggg aacaggcggg gacgcccgcg tctgatggga gtcgcggtcc
      721 gggcagcccc gcggccaggg gtcggtcaga ggccgctgcc tctgctacag cagcgctccg
      781 gagtcccggg ccacggaaaa gccaggcctg ggccgagggc ggctctccgc gcagcgcgcg
      841 cagcctgaag ggggatcctc ctcggggtcc cgcgggcaga ggaccggaga gtcctctccg
      901 tagccccgcg cgggctaagg ccagcccgct ccgcagaagc gccgaatccc gagatgcgac
      961 cgccagtgcc acgccagccc cgccggcgcc cccggtgccc ccggtgtcgt cggtgcgggt
     1021 ggtgagtgcc tccggggcgg tctccgagga gatcgaggtc ctggaaatgg tgagggagga
     1081 cgaggcgcca cagccgctcc cggactcgga gcagccgccg tctgccgcgg agctggagtc
     1141 tccggccgaa gaatgcagct gggccgggct tttctccttc caggatctgc gagccgtgca
     1201 tcagcagctg tgctcggtaa actcccagct ggagccgtgt ctgccggtgt tccccgaaga
     1261 gccgtcaggc atgtggacgg tgctgtttgg gggcgccccc gagatgaccg agcaggagat
     1321 cgacgctcta tgttaccaac tccaggtata cctgggccac ggcctggaca cgtgtggctg
     1381 gaagatcctt tctcaggttc ttttcaccga gacggatgat ccggaggagt attacgaaag
     1441 cctcagcgag ctgcggcaga agggctatga agaggtgctt cagcgggcca ggaggcgcat
     1501 ccaggagctc ttggacaagc acaagactat agaaagcatg gtagagcttt tggacttgta
     1561 tcagatggag gatgaagcct acagcagcct tgcagaggcc acaactgaac tctaccagta
     1621 tttacttcag ccattccgag acatgcgaga actggccatg ctacgaagac agcagatcaa
     1681 gatttccatg gagaatgatt atttgggccc tcgaagaatt gagagtctac agaaagaaga
     1741 tgctgactgg cagcggaaag ctcacatggc tgttttgtct attcaggatc tcaccgtcaa
     1801 atattttgaa ataacagcaa aagctcagaa agctgtgtat gatcggatgc gagcagatca
     1861 gaagaaattt ggcaaagcat cgtgggcagc agctgctgag cgaatggaaa aactccagta
     1921 tgcagtttct aaagagactt tgcagatgat gagagctaaa gaaatttgtc tggaacagaa
     1981 gaaacatgca ctaaaagaag agatgcaaag cttacagggt ggtacagaag ctatagctcg
     2041 attggatcag ctggaatctg actactatga tctgcaactt cagttgtatg aagtacagtt
     2101 tgaaatcttg aagtgtgaag agttgttatt aactgcacag ctggagagca tcaagagact
     2161 tatatcagaa aagagagatg aagtggtgta ctacgacact tacgaaagca tggaggccat
     2221 gctggagaag gaagagatgg cagcgtctgt gcacgcccag agggaagagc tacagaaact
     2281 gcagcagaag gcacgccagc tggaagcaag aaggggccgt gtctcagcca agaaagccta
     2341 cctcagaaat aaaaaagaaa tttgcattgc aaaacaccat gagaagttcc agcagcgttt
     2401 tcagagtgaa gatgaatata gagcccatca tacaatacaa ataaagagag acaaattgca
     2461 tgatgaagag gaaagaaaaa gtgcctgggt tagccaagag agacagagga cactggatag
     2521 acttcgaaca tttaagcaga ggtaccccgg gcaagtcatc cttaagtcga ccagattacg
     2581 agtggcgcat tcaagaagaa aaagcacagc aagccctgtg ccctgtgagg agcagtgtca
     2641 ctctctgcca acagtgctgc aggggcagga gaagacagag gtgggaggag gaggaagcca
     2701 gcttgggcct tcacagacag cagaacccca gagccttgtc caacttgaag acacttcatc
     2761 agaacaactt gaatccacct cattacctcc tcgtgctgtc gtcagctctg aactgcctcc
     2821 tccacagtca gctccactgt tgactagtat tgaccccaaa ccgtgttctg ttactataga
     2881 tcctctccca ccccctcttc ctccaacacc tccccctccc ccacccccac ccccacctcc
     2941 acccccaccc ctgcctgttg caaaggacaa tggggcctcc accactgcag agacactgga
     3001 gaaagatgca cttaggacgg agggcaatga gaggagcatc ccaaagtcgg ccagtgcccc
     3061 cgcagcacac ctctttgata gcagccagct ggtcagcgca cggaaaaagc tcagaaagac
     3121 tgtggaaggg ctgcagagga ggagagtgag ttcacccatg gatgaagtgt tagcatcctt
     3181 gaagcgtggt agctttcatc tgaaaaaggt tgaacagcgg actctgcctc cttttcctga
     3241 tgaagatgat agtaataata ttttggcgca gataaggaaa ggggtaaagt tgaagaaggt
     3301 tcagaaggaa gttttgagag aatccttcac acttctgcct gataccgacc ctttgacacg
     3361 gagtatccac gaagctctaa gaagaatcaa agaagcgtcc ccagagtcag aggatgagga
     3421 agaggctttg ccgtgcacag actgggagaa ctagcaggtg acttaagaga gaagaaaaat
     3481 acccatggat gaagactggc tctggttcct ttggggaaaa aatctaagct cttggtccca
     3541 caattggatt ccattatgtc ctgagtatat tgacaaagtg gtttgaaaaa ggaagcacaa
     3601 acgggaggtt actactgtcc agtccctctc attgatagtg caatgttccc gactgcagag
     3661 agaacaagcc tcctggagac ggctgttcct tccccacccc tcctccccat ctgcccaatc
     3721 ataatctcat agtggccagt cccattgcta tgaattggaa gaacactggg ttggcagagg
     3781 tctgctgtac gagctacttt gggattcatc tttcagtgaa ctgagaagat ctgtgctgaa
     3841 gcacagccgc ttccatgtca gcttgtagag acagagagac atgctacaga agacattgat
     3901 caaggtagtt atggtcagga attaaaaaaa aaccatgaaa tgcacttaaa atttccacat
     3961 tattcatctc cagagaagtt cagtatctga gaagccagtg gagatatacc tatcaatgtg
     4021 tgcaccagaa cacgacacat ttaacaaggc atatttttaa gaggccacag tcttacattt
     4081 tgtaagaatt tgaagttaaa atttccatgc ttttaaaata gcgtttcata attctgaatt
     4141 tagaatagtt tgaattttat gtgcatcctg tttatgagaa gcaatgcttt gtaatttgat
     4201 aatgttattt ttagtctttt tgtttgaact actgcttgat tactataact caagactttc
     4261 ctattgagaa tcaaaaaagc aggattcaac agtggggatt caaattacaa gccgtgcacc
     4321 cggttacgtt tttattgtta tgctccgtgg tgaggagcat gtattcagta aaggtccaga
     4381 aggcagctgg gcccgaagcc tccagctggc attttagtgg ttttgttttt tgttttttta
     4441 ttctgtgtat agaactttag gagaacgttt gttgctgtca ctaaatcttt aaactcacat
     4501 gtgtagatcc aatgctgacc tggctgtatc ttaaagggtc catttatgaa cggggccggc
     4561 agggattgtc attggtttga ttatgtgaac atgcatgagg gcagatatgc tggacccagt
     4621 ttacagtaca ttgtagtgtg tgctttatat ggaggaattg aaataccaaa aagaacttca
     4681 tttgtagaaa gttctttccc ggcgttgccc agaatcttcc cagaagcgaa agcctctcaa
     4741 tgcccgccat agttttcctc caggaacatg gcttcctggt cacttttaag agatgtgttt
     4801 ctttaattat gaaaaagatt cttgtaacgg gttatagaaa accaaatttt tgcacttaaa
     4861 acattcatgt ttattgatga gactgggagc tcatgtagca attactttat atattggttt
     4921 tagtccaagc ataattcaca catcttgtcc gcaacaatta aaagagctct gatatataag
     4981 cctcattcta agatgatctg tgtgtccttt atacccccag taaagcacca aaatgtgttt
     5041 aacccaaaga gtcattggct agataaagaa atatttgaaa agcttcaaaa cttacaaatg
     5101 ttctaaaaat cagccatcgt ttataaactt gtaatattta cagatctatc catcgatgca
     5161 ttatatattc aggttctttg cttacttact tctgaggcca ggccctgctg tgtagccctg
     5221 gctggcctag gatttgctgt gcaggccagg cactctgcag cagtctgctt ctctctgcct
     5281 ctcttacagg tatgcaccaa gatgcctgcg tccctggttg tttttggttt ttgttttttt
     5341 ttaagattca ttttaaaaat tactttaaat tatgtaaact atgtacagag gctctggctt
     5401 ggttactagg aaccaaactt gggtcttttg aaggagcagt gtgtgctctt aatctctgag
     5461 caatctctcc agtccctttt tttaaactat aggaaaatat gaaatataat ttatcaaaag
     5521 ccattgtgtt gtactctgtt tagcaccacg tgcctgggct ttgtaagtgg ggatgaactg
     5581 ggacaatgag cagctctcag cacatcctga caatccaaga ttacagcctg gagtgagcct
     5641 tcagcctgtt ttcaagtaaa tgattctctc ccaacatgcc agcttctctg cctcgggagt
     5701 cttgtttttg tactggagca tggctcagta gtaaagtgca acaccttatg ttccatctct
     5761 agcattggct tcttaatcct caagaaaaga tttttacttc acaaaatcac acacattgga
     5821 gttactcata ataatataat ttaaaataac tagtatacat gtgttcatca aatcaccagg
     5881 tgagccctca ttaatttaaa gtggttttag ggccccagga aaatgacaat aagcatgatg
     5941 tggtttttct cccttacttt cctagacaca gaagttttgc ttaattttag atgcagtcat
     6001 cagaccataa gtgataagct ctggccttca gagttcattc atgtgtctag ttgtcatggc
     6061 agtcagtcaa tgtttccagt tcccagtgta gttagccttc cacggtgccc agtatccaca
     6121 gacactgctt gtctttgctg ttcccaagtg ttttatactg aagatgggaa agcaggagtt
     6181 aactagatgc ttaatctagt gttattattc atacttgaat gtcaaatttc aaatatgtcc
     6241 ccgatacaac caaaataatg tatagtagcc gatgtgctat gtatagaaaa gatatctcta
     6301 ggttaaaggt cctagttggt ttttagtagt aagaaattgc tggcgaatga ggattttagg
     6361 gtctaagcaa tgaccctagt taaagagtgc tttatatagg gatatgaagt tcatgagaca
     6421 gcataaaaac aatcattcct tagttgctca tcatgcactt aaaactttct tccccctccc
     6481 cattcctgag acagggtttc tccatgtggc cctagctgct ctggaactcc ctctatagat
     6541 caggctggcc tcaaactcag ggatttgcct gcctctgcct cccgagtgct gggactaagg
     6601 catgtgcgac tacacctgtt gcaaaatcca ttttttaaaa gatactggtg tagtatagtg
     6661 aacactttgt ggactctaca gtgtgtgtga acgttcagag ggttctcatt tgtataaata
     6721 tgaatgtcga acaatccttg gtgccacagt aagtcctaga atgtggtaag ttgcacggtg
     6781 tactgcagac accacacact aagaattaga attcagtagg atatagaatg acagcatcca
     6841 catggcatgg gggcacgcac attgatacag ttgcattctc tagactccct gagacttctt
     6901 tatggaatcc actcacagaa tatgtttgta tttatttaaa ccaatatttt gagtccagcc
     6961 ttgtaataca ctcatcaaca gacatcaatc tgcacagtga ctttgggtct ttagtgggcc
     7021 tgtcagggag ttttgagctt tcttacattt taccagtaaa ataagtatag atcctgacca
     7081 actgcaggac atttcagact attgcttaag atgcaagcac ttgacaggga aagcggagac
     7141 ctttaatttt tcctcatctt tgcactgaat ataaatgatt atataaagct aaatgtgcat
     7201 attgaacatt ttatttgtgc ttggtgttgc cagtgaccat caagacttta gatggaagag
     7261 ggtgagaaag cagaagcacc ttactgctga gcacactgtg ttcaggcctc acgactgcag
     7321 tcgtgaggcc tgaactttat gttagagcat gttaaaatcc tgcctaattg cttggaaata
     7381 ggaggcgatg gtatttttag cctatttatg taatgtaact taaaaggttt tcccagaaaa
     7441 tgagtttata ttgttatcta aactatccca tgtgtaaaca gaagctttta aaggtaggag
     7501 gcagtcctga tgcagagaga gacaatgaga gagacagtcc actaaatgtt ccctgagtta
     7561 tgttaaagat gttcttattt taaatttttt gttttgtcca cagtaaatat acaatgtggc
     7621 atttatatga cttaatggat tgagctccaa gtttataaat gtaccctctc ttcaaagcaa
     7681 attttttggg gccactgtaa ggtgcatata gagaaattac ctctgaggat gacatgctaa
     7741 agtgttcatg agagctgctt cacttccacc ctcagagaat cacttgtttt gagagcaagg
     7801 ggaagtttct tttttttttt tttttgtaga ttcacttata gttaacagtg gcccaattta
     7861 gggtattgga aatgagtagg gaagacaatg aaatgtttaa aaactaaagg catgggtgtt
     7921 agagttgagt tttaacagga gaaaacattt tttcttgcat gttgtatagt taactgtcaa
     7981 ggggtgtaat gcggcatttt aggtttctcc atgcaaattc ctttgtcttt cctatgaagt
     8041 ctttgcagtt accggtggca tttccctttc ctgtggtttc cccttatttt gtgtgatgta
     8101 acaagggttg catcctatag cagtttctta caatgttttc gacacagtcc ccactgcctt
     8161 gttgaatctc tctctgtact gtatgcactg ccaagtgtga gaccataata tgtagtttaa
     8221 tgagaaacgg aaggatgcag gtcagtttgc atgagtaaag cccactgggg ctacataaac
     8281 tgacactttt gtcattttac ccagttgtgg gtaaatgaag actacaatgg cagactgact
     8341 caccattact tgctttgtgc aatgttataa aggcaaaaca ctatgcacta tgcttggctt
     8401 tacagatggc attcccacca tgacattaag tggattgtcc acagcatact ataaatgcca
     8461 tctcttgcaa atttatatac gtaaatatgc tcaattaaca cttaagtatt acaagtataa
     8521 ggaaactact aagcaggcat ttatagcaat actatgaaat ctccaatcac tgttttgact
     8581 gtcgccttct ccttagtgca gcctttctgc atcgtagttg ctgctttttt acatttcaca
     8641 ctcctgactt cagagttaag tacttgctca tccagtgttg cactcacctt tcttattgta
     8701 catgcaatgt aacaacacac agttttggtg cttaacaata ttcctttttt tctttaataa
     8761 aggatattta tttgaattaa
//
