LOCUS       NM_001114637            1383 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus jumonji domain containing 7 (Jmjd7), mRNA.
ACCESSION   NM_001114637
VERSION     NM_001114637.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1383)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1383)
  AUTHORS   Liu,H., Wang,C., Lee,S., Ning,F., Wang,Y., Zhang,Q., Chen,Z.,
            Zang,J., Nix,J., Dai,S., Marrack,P., Hagman,J., Kappler,J. and
            Zhang,G.
  TITLE     Specific Recognition of Arginine Methylated Histone Tails by JMJD5
            and JMJD7
  JOURNAL   Sci Rep 8 (1), 3275 (2018)
   PUBMED   29459673
  REMARK    GeneRIF: Recognition between JMJD5/JMJD7 and histone substrates is
            specific, which is reflected by the binding data between enzymes
            and substrates. High structural similarity between JMJD5 and JMJD7
            is reflected by the shared common substrates and high binding
            affinity.
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL833774.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC016255.1, SRR7652917.80965.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-94                AL833774.4         160455-160548       c
            95-248              AL833774.4         157820-157973       c
            249-502             AL833774.4         157489-157742       c
            503-559             AL833774.4         157159-157215       c
            560-655             AL833774.4         156629-156724       c
            656-732             AL833774.4         156380-156456       c
            733-892             AL833774.4         156031-156190       c
            893-1383            AL833774.4         155427-155917       c
FEATURES             Location/Qualifiers
     source          1..1383
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 60.09 cM"
     gene            1..1383
                     /gene="Jmjd7"
                     /note="jumonji domain containing 7"
                     /db_xref="GeneID:433466"
                     /db_xref="MGI:MGI:3845785"
     exon            1..94
                     /gene="Jmjd7"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..981
                     /gene="Jmjd7"
                     /EC_number="1.14.11.63"
                     /note="jmjC domain-containing protein 7; jumonji
                     domain-containing protein 7; L-lysine (3S)-hydroxylase
                     Jmjd7"
                     /codon_start=1
                     /product="bifunctional peptidase and (3S)-lysyl
                     hydroxylase Jmjd7"
                     /protein_id="NP_001108109.1"
                     /db_xref="CCDS:CCDS50676.1"
                     /db_xref="GeneID:433466"
                     /db_xref="MGI:MGI:3845785"
                     /translation="MAEAALEAVRRALQEFPAAARDLNVPRVVPYLDEPPSPLCFYRD
                     WVCPNRPCIIRNALQHWPALQKWSLSYLRATVGSTEVSVAVTPDGYADAVRGDRFVMP
                     AERRLPISHVLDVLEGRAQHPGVLYVQKQCSNLPTELPQLLSDIESHVPWASESLGKM
                     PDAVNFWLGDASAVTSLHKDHYENLYCVVSGEKHFLLHPPSDRPFIPYNLYTPATYQL
                     TEEGTFRVVDEEAMEKVPWIPLDPLAPDLTQYPSYSQAQALHCTVRAGEMLYLPALWF
                     HHVQQSHGCIAVNFWYDMEYDLKYSYFQLMDTLTRATGLD"
     exon            95..248
                     /gene="Jmjd7"
                     /inference="alignment:Splign:2.1.0"
     exon            249..502
                     /gene="Jmjd7"
                     /inference="alignment:Splign:2.1.0"
     exon            503..559
                     /gene="Jmjd7"
                     /inference="alignment:Splign:2.1.0"
     exon            560..655
                     /gene="Jmjd7"
                     /inference="alignment:Splign:2.1.0"
     exon            656..732
                     /gene="Jmjd7"
                     /inference="alignment:Splign:2.1.0"
     exon            733..892
                     /gene="Jmjd7"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1383
                     /gene="Jmjd7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1355..1360
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Jmjd7"
                     /note="hexamer: AATAAA"
     polyA_site      1373
                     /gene="Jmjd7"
                     /note="major polyA site"
ORIGIN      
        1 ataggggcgg gttcttgtcc cgcggccgtc atggcggagg cggctctgga ggcagttcgg
       61 agggcgttgc aagagttccc ggcggcggct cgcgacctca atgtacctcg tgttgtgccc
      121 tacctggatg agcccccaag cccactctgc ttctaccggg attgggtgtg ccccaacagg
      181 ccctgcatta tccgaaatgc tctgcagcac tggccagccc tccagaagtg gtccctgtcc
      241 tacttaagag ccacggtggg ctccacggag gtgagtgtgg ctgtgactcc agatggttat
      301 gcggacgcgg tgcgagggga ccgctttgtg atgcctgctg aacgccgcct gcccataagc
      361 catgtactgg atgtgttgga aggtcgggcc cagcacccag gagtcctcta tgtgcagaaa
      421 cagtgttcca acctgcccac tgagctgccc cagcttctgt ctgacattga gtcccatgtg
      481 ccctgggcct ctgagtcact ggggaagatg cctgatgccg tgaacttctg gctgggtgat
      541 gcatctgcag tgacatcctt gcacaaggac cactatgaga atctgtactg tgtagtctct
      601 ggcgagaaac acttcttgtt acatccaccc agcgaccggc ccttcatccc ttacaatctc
      661 tacacaccag caacctacca gctgactgaa gagggcactt ttagggtggt ggacgaggaa
      721 gccatggaga aggtaccctg gatcccactg gaccccttgg ctccagacct gacccagtac
      781 cccagttaca gccaggcaca ggcccttcac tgcacagtgc gggccggcga gatgctgtac
      841 ctgccagctc tgtggttcca ccatgtccag cagtcccacg gctgtattgc tgtgaatttc
      901 tggtatgaca tggagtatga cctcaagtac agttactttc aactgatgga caccctcacc
      961 agggccacag gccttgactg aagagaccct cagacactgc aaaggacagc ggggatcgac
     1021 ggggtcattt gattctggag gcagcctaga gttcgaatat gtcctggctg ctgcccaggt
     1081 tcccgcctgt gttgggatca ggcattgcag gaacttggaa tttagttgga ggtccaagaa
     1141 atgccagaca ggtctgggtg aacgtgccca ggaaattgcc acacaggtga caaggaagca
     1201 cggatcaggt acagcagtgc ctctcaccag tgctatgacc ttgggtgagt cactgcatgt
     1261 tagcatcagt cccttgtctg taaagtggag ataataatgg ctctggctcc cagagctttg
     1321 ggaataggca tgggccaatg tagaggaagc ggtcaataaa aggtgacact tgatacactt
     1381 gtt
//
