LOCUS       NM_001401054            4401 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus janus kinase and microtubule interacting protein 1
            (Jakmip1), transcript variant 4, mRNA.
ACCESSION   NM_001401054 XM_011240790
VERSION     NM_001401054.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4401)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4401)
  AUTHORS   Berg,J.M., Lee,C., Chen,L., Galvan,L., Cepeda,C., Chen,J.Y.,
            Penagarikano,O., Stein,J.L., Li,A., Oguro-Ando,A., Miller,J.A.,
            Vashisht,A.A., Starks,M.E., Kite,E.P., Tam,E., Gdalyahu,A.,
            Al-Sharif,N.B., Burkett,Z.D., White,S.A., Fears,S.C., Levine,M.S.,
            Wohlschlegel,J.A. and Geschwind,D.H.
  TITLE     JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates
            Synaptic Function and Autistic-like Behaviors in Mouse
  JOURNAL   Neuron 88 (6), 1173-1191 (2015)
   PUBMED   26627310
  REMARK    GeneRIF: JAKMIP1 loss dysregulates neuronal translation during
            synaptic development and results in social deficits and other
            autistic-like behaviors.
REFERENCE   3  (bases 1 to 4401)
  AUTHORS   Tamplin,O.J., Cox,B.J. and Rossant,J.
  TITLE     Integrated microarray and ChIP analysis identifies multiple Foxa2
            dependent target genes in the notochord
  JOURNAL   Dev Biol 360 (2), 415-425 (2011)
   PUBMED   22008794
REFERENCE   4  (bases 1 to 4401)
  AUTHORS   Vidal,R.L., Valenzuela,J.I., Lujan,R. and Couve,A.
  TITLE     Cellular and subcellular localization of Marlin-1 in the brain
  JOURNAL   BMC Neurosci 10, 37 (2009)
   PUBMED   19386132
  REMARK    GeneRIF: Marlin-1 is enriched in restricted areas of the brain
            including olfactory bulb, cerebral cortex, hippocampus and
            cerebellum; it is abundant in dendrites and axons of hippocampal
            neurons, associated with microtubules at the ultrastructural level.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4401)
  AUTHORS   Costa,V., Conte,I., Ziviello,C., Casamassimi,A., Alfano,G.,
            Banfi,S. and Ciccodicola,A.
  TITLE     Identification and expression analysis of novel Jakmip1 transcripts
  JOURNAL   Gene 402 (1-2), 1-8 (2007)
   PUBMED   17761393
REFERENCE   6  (bases 1 to 4401)
  AUTHORS   Vidal,R.L., Ramirez,O.A., Sandoval,L., Koenig-Robert,R., Hartel,S.
            and Couve,A.
  TITLE     Marlin-1 and conventional kinesin link GABAB receptors to the
            cytoskeleton and regulate receptor transport
  JOURNAL   Mol Cell Neurosci 35 (3), 501-512 (2007)
   PUBMED   17532644
REFERENCE   7  (bases 1 to 4401)
  AUTHORS   Couve,A., Restituito,S., Brandon,J.M., Charles,K.J., Bawagan,H.,
            Freeman,K.B., Pangalos,M.N., Calver,A.R. and Moss,S.J.
  TITLE     Marlin-1, a novel RNA-binding protein associates with GABA
            receptors
  JOURNAL   J Biol Chem 279 (14), 13934-13943 (2004)
   PUBMED   14718537
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC115722.12 and AC110238.10.
            
            On Feb 1, 2022 this sequence version replaced XM_011240790.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.785889.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164133
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-248               AC115722.12        46055-46302         c
            249-511             AC110238.10        64410-64672
            512-1006            AC110238.10        70301-70795
            1007-1216           AC110238.10        79810-80019
            1217-1336           AC110238.10        80939-81058
            1337-1483           AC110238.10        83987-84133
            1484-1624           AC110238.10        84785-84925
            1625-1684           AC110238.10        86433-86492
            1685-1813           AC110238.10        96616-96744
            1814-1942           AC110238.10        97953-98081
            1943-2026           AC110238.10        100115-100198
            2027-2089           AC110238.10        102454-102516
            2090-2188           AC110238.10        104051-104149
            2189-2290           AC110238.10        106551-106652
            2291-2344           AC110238.10        107179-107232
            2345-2410           AC110238.10        107765-107830
            2411-2479           AC110238.10        113411-113479
            2480-2569           AC110238.10        114730-114819
            2570-2773           AC110238.10        120787-120990
            2774-2839           AC110238.10        121967-122032
            2840-2887           AC110238.10        127156-127203
            2888-4401           AC110238.10        128275-129788
FEATURES             Location/Qualifiers
     source          1..4401
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 19.66 cM"
     gene            1..4401
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /note="janus kinase and microtubule interacting protein 1"
                     /db_xref="GeneID:76071"
                     /db_xref="MGI:MGI:1923321"
     exon            1..248
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            249..511
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             383..2917
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /note="isoform 4 is encoded by transcript variant 4;
                     gamma-aminobutyric acid (GABA-B) receptor binding protein;
                     GABA-B receptor-binding protein; multiple alpha-helices
                     and RNA-linker protein 1"
                     /codon_start=1
                     /product="janus kinase and microtubule-interacting protein
                     1 isoform 4"
                     /protein_id="NP_001387983.1"
                     /db_xref="GeneID:76071"
                     /db_xref="MGI:MGI:1923321"
                     /translation="MSKKGRSKGDKPEAETDSVQMANEELRAKLTNIQIEFQQEKSKV
                     GKLRERLQEAKLEREQEQRRHTAYISELKAKLHEEKTKELQALREALIRQHEQEAART
                     AKIKEGELQRLQATLNVLRDGAADKVKTALLADAREEARRTFDGERQRLQQEILELKA
                     ARKQAEEALSNCMQADKAKAADLRAAYQAHQDEVHRIKRECERDIRRLMDEIKGKERV
                     ILALEKELGVQTGQTQRLLLQKEALDEQLVQVKEAERHHSSPKRELPPGIGDMAELMG
                     GQDQHMDERDVRRFQLKIAELNSVIRKLEDRNTLLADERNELLKRSRETEVQLKPLVE
                     KNKRMNKKNEELLHSIQRMEEKLKSLTRENVEMKEKLSAQASLKRHTSLNDLSLTRDE
                     QEIEFLRLQVLEQQHVIDDLSLERERLLRSKRHRGKSLKPPKKHVVETFFGFDEESVD
                     SETLSETSYNTDRTDRTPATPEEDLDETTTREEADLRFCQLTREYQALQRAYALLQEQ
                     VGGTLDAEREARTREQLQADLLRCQAKIEDLEKLLVEKGQDAAWVEEKQVLMRTNQDL
                     LEKIYRLEMEENQLKSEMQDAKDQNELLEFRVLELEERERRSPAFNLQITTFPENNSS
                     ALQLFCHQEGVKGVNISELMKNLDILGDNGNLRNEEQVAVIQAGTVLALCEKWLKQIE
                     GTEAALTQKMMDLEKEKDQFSRQKGYLEQELDYRKEALDQAYLVGPEKIQDLEATLYN
                     ALQQEPGRRASEALSASQREDLQAAVEKVRRQLLRQSREFDSQILRERMELLQQAQQK
                     IREMEGKLELQRRQLKELEEKHSFCGLDDSHAPPRTRARQRAFGIT"
     exon            512..1006
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..1216
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..1336
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1483
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1484..1624
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1625..1684
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1685..1813
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1814..1942
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1943..2026
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2027..2089
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2090..2188
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2189..2290
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2291..2344
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2345..2410
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2411..2479
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2480..2569
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2570..2773
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2774..2839
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2840..2887
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2888..4401
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4375..4380
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /note="hexamer: ATTAAA"
     polyA_site      4401
                     /gene="Jakmip1"
                     /gene_synonym="5830437M04Rik; C330021K24Rik; Gababrbp;
                     Marlin-1"
                     /note="major polyA site"
ORIGIN      
        1 agccgctagc gtgcggcgcc ggtccccgcc gttcccgcat cgcacacggg ttccccacgg
       61 gccgagcctc ctcggctacg gtccaggttt tctttatttt cattttttgc atgcattcat
      121 tttctgttct atctcgtcca ttttaaggca gcggcgacgg cgacagcagc gtaggtgcgc
      181 gcggggaggg ggcggccgga gaatgcggct ccccgctgct gctcggcttg tgtcggagcg
      241 tcaagcagac tcgccagtga tggtgtgcac agaggacgag cggagccctg tacgactgct
      301 tagcacagcc gagctggtag ctgtactcgc tggtgggcgg gcgtgaacct caggacctca
      361 gtgtctcact ccaagaggaa acatgtctaa aaagggccgc agcaaggggg acaagcccga
      421 ggcggagacg gactctgtgc agatggctaa tgaagagctg cgcgccaagc tgaccaacat
      481 ccagattgag ttccagcagg agaagagcaa ggtggggaag ctgcgggagc gtctgcagga
      541 ggccaagctg gagcgcgagc aggagcagcg tcgccacacc gcctacatct cggaactcaa
      601 ggccaagctg cacgaggaga agacgaagga actgcaggcg ctgcgcgagg cgctcatccg
      661 gcagcacgag caggaggcag cgcggaccgc caagatcaag gaaggtgagc tgcagcggct
      721 gcaggccacg ctgaatgtgc tgcgcgatgg cgccgcagac aaagtcaaga ctgcattgct
      781 ggccgacgcg cgcgaggagg cgcgcaggac ctttgatggc gagcgccagc ggctgcagca
      841 ggagatcctg gagctgaagg ctgcgcgcaa acaggcggaa gaggcactca gtaactgcat
      901 gcaggcagac aaggccaaag ccgccgacct gcgcgctgcg taccaggcgc accaggatga
      961 ggtgcaccgc atcaagcggg agtgcgaacg tgacatccgc agactgatgg acgagatcaa
     1021 agggaaggag cgggtgatcc tggccctgga gaaggagctt ggtgtgcaaa ccgggcagac
     1081 ccagcggctg ctgttacaga aggaggctct ggatgagcag ctggtccagg tcaaggaggc
     1141 agaacgccac cacagcagcc caaagaggga gcttcctcct ggcattggtg acatggcgga
     1201 gcttatgggt ggccaggatc aacatatgga tgagcgagat gtgaggcgat ttcaactgaa
     1261 aattgctgaa ctgaattcag tgattcggaa gctagaggac aggaacaccc tgctggctga
     1321 cgagaggaac gaactgctga agcgctctcg ggagacggag gtgcagctga agccgctggt
     1381 ggagaagaac aaacgcatga acaaaaagaa cgaggagctg ctgcacagca tccagaggat
     1441 ggaggagaag ctcaagagcc tcacgaggga gaacgtggag atgaaagaaa agctgtctgc
     1501 tcaggcctcg ctaaagcgac acacgtccct gaatgacctc agtctgacca gggacgagca
     1561 ggagatagag ttcctgaggc tgcaggtgct ggaacagcag catgtcatcg atgacctctc
     1621 tctggagaga gaacgcctgc tgcgctccaa gaggcatcga gggaagagcc tgaagccccc
     1681 caagaagcat gttgtggaga cattttttgg atttgatgag gagtccgtgg actctgaaac
     1741 attgtccgag acgtcctaca acacggacag gacagaccgg accccagcca cgccggaaga
     1801 ggacttagat gagaccacaa ccagagaaga ggctgacctg aggttctgcc agctgaccag
     1861 ggagtaccag gctctgcaga gggcttatgc cctgcttcag gagcaggttg gggggacact
     1921 ggatgctgaa agggaggccc ggactcggga gcagcttcag gccgacctgc tgaggtgcca
     1981 ggccaaaatc gaggacttag agaagctgct ggttgagaag ggacaggacg ctgcgtgggt
     2041 agaggagaag caggtactca tgaggacaaa ccaggacctg ctggagaaga tttacagact
     2101 ggagatggag gagaaccagc taaagagcga aatgcaagac gccaaggacc agaacgagct
     2161 gttagaattc agagtgctag aactcgaaga gagagagcgg aggtcgccag cctttaacct
     2221 ccaaatcacc accttccccg agaacaacag cagcgccctc cagctgttct gtcaccagga
     2281 aggagtaaag ggtgtgaata tctctgaact tatgaagaac ttagatattc ttggcgataa
     2341 tgggaatttg aggaatgaag agcaggttgc agtaatccaa gcgggaactg tgcttgccct
     2401 ctgtgaaaag tggctgaagc agatagaggg gacagaggca gccctcacgc agaagatgat
     2461 ggacctggag aaggagaagg accagttcag caggcagaaa ggctacctgg agcaggagct
     2521 ggactacagg aaagaagccc tcgaccaggc ctacctggta ggaccggaaa aaatccagga
     2581 cctggaggcc accttgtaca atgcactgca gcaggagcca gggcggaggg ccagtgaggc
     2641 actgagtgcc agccagcgtg aggacctcca ggcagcagta gagaaggtgc gcagacagct
     2701 gctgcgtcag agccgggagt ttgacagcca gatcctgcgg gagcgaatgg agctgctaca
     2761 gcaagcccag cagaaaatcc gggagatgga gggcaagctg gagctgcaga ggcgccagct
     2821 gaaggagcta gaggaaaagc attcattctg tggccttgac gactcccatg cgccgccgag
     2881 aactcgggct agacaaagag cttttggaat cacctgagtc cccgtggtgc cccatcctca
     2941 ctgaaaccaa aatccaacag caacaaagct tttcaaagtc cagagcctga acacagaatt
     3001 tacgcacatt tgacagtcac ttaaagggga ggcctgggga cctggccagc ctctgctgtg
     3061 gagctctgca ggacaatggc aagccttccc agtatcccca ctgtgacatc ttcaggagcc
     3121 aagggcaaag gtggatctgg atggcagaaa tcgataagtg caattagtgg aagcccagga
     3181 catgggagct actaccttgg gggataggca caagccctgt ccccgtgttg tgtgcctccc
     3241 tgaaggcacc gcgagtgcct agagggactc agacagcccc tctgccccat gtacataaat
     3301 ctccatggac tgagtgtgtt cttccagagt ctgtctgcca gagcaaccaa cgaaacctct
     3361 gactccatgc acagctggac tggcagctag tgaccagcaa gagagagttg gaatcgccaa
     3421 tgtggggacc ctgtggattg tagatttctg aggaaagctg aaggctctga cacttatagg
     3481 tgtgacactg cataagtccc agagcatggc tgtgcctaag tccagggaga agtgaggaca
     3541 gagaaaacag acccaagcta tctgttgtaa tttgtaggga tatcctgtga aggagctcag
     3601 gctggtagtg cagcactcag aggctctgag gtctgaggtc tgaggccagg agcacccttt
     3661 accataaaga aaactactgt agagccttca ctgcccagga ttcttggtag agagtagagt
     3721 catctcctca ggtgttgggg cctcccagag cacagggggt aagataaagg gtagtgcact
     3781 ctaagttcac tgggaacaag atgctagaag tcgacttcca gaggaaattc cccaagaagt
     3841 aactttgggg aatctagggc aggtagggtg gggaacctcc aaaaggaact tgcctatgtg
     3901 gctatactct ttcaaacttg gggtggagag aatgttagcc atcagattga cagtgtgaaa
     3961 aaaaagatag gacgctgagt ctgggtgcag gagcgtgtgg tgaggctcga tgagacacgg
     4021 aggcagcagg ccagatgaag cctcttgctg tgtagttaca ggaccaagct agtggcacca
     4081 tgatttcctg gaagcaagaa gattgactgg ggctcagatc aggcccattg atggaaccat
     4141 ggagcaggga ccggacattg tagggaagcc agattcaaac acagagaggc gaggacagtg
     4201 ctctggacgg aagaggggct gtccagacag gaggtcatcc cgggagctat gacgtctcca
     4261 gcttgaagca aacacagcag aatggctcag aagtgttgac tctctgctga aatctgagtc
     4321 ccccaacacc tgtgacccat aagcctctgc aacctaccac tacccagtgg cttaattaaa
     4381 tcccaaggaa tttatctttg a
//
