LOCUS       NM_001130184            5486 bp    mRNA    linear   ROD 07-MAY-2024
DEFINITION  Mus musculus jade family PHD finger 1 (Jade1), transcript variant
            2, mRNA.
ACCESSION   NM_001130184
VERSION     NM_001130184.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5486)
  AUTHORS   Wang,J., Chai,B., Yang,Y., Chen,C., Ren,Y., Li,Y., Wang,Z.Q. and
            Li,T.
  TITLE     JADE1 is dispensable for the brain development in mice
  JOURNAL   Biochem Biophys Res Commun 695, 149421 (2024)
   PUBMED   38171233
  REMARK    GeneRIF: JADE1 is dispensable for the brain development in mice.
REFERENCE   2  (bases 1 to 5486)
  AUTHORS   Matoba,S., Kozuka,C., Miura,K., Inoue,K., Kumon,M., Hayashi,R.,
            Ohhata,T., Ogura,A. and Inoue,A.
  TITLE     Noncanonical imprinting sustains embryonic development and
            restrains placental overgrowth
  JOURNAL   Genes Dev 36 (7-8), 483-494 (2022)
   PUBMED   35483741
REFERENCE   3  (bases 1 to 5486)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5486)
  AUTHORS   Borgal,L., Rinschen,M.M., Dafinger,C., Liebrecht,V.I., Abken,H.,
            Benzing,T. and Schermer,B.
  TITLE     Jade-1S phosphorylation induced by CK1alpha contributes to cell
            cycle progression
  JOURNAL   Cell Cycle 15 (8), 1034-1045 (2016)
   PUBMED   26919559
  REMARK    GeneRIF: Interactome analyses revealed that the Jade-1S mutant
            unable to be phosphorylated by CK1alpha has an increased binding
            affinity to proteins involved in chromatin remodelling, histone
            deacetylation, transcriptional repression, and ribosome biogenesis.
REFERENCE   5  (bases 1 to 5486)
  AUTHORS   Siriwardana,N.S., Meyer,R., Havasi,A., Dominguez,I. and
            Panchenko,M.V.
  TITLE     Cell cycle-dependent chromatin shuttling of HBO1-JADE1 histone
            acetyl transferase (HAT) complex
  JOURNAL   Cell Cycle 13 (12), 1885-1901 (2014)
   PUBMED   24739512
REFERENCE   6  (bases 1 to 5486)
  AUTHORS   Tzouanacou,E., Tweedie,S. and Wilson,V.
  TITLE     Identification of Jade1, a gene encoding a PHD zinc finger protein,
            in a gene trap mutagenesis screen for genes involved in
            anteroposterior axis development
  JOURNAL   Mol Cell Biol 23 (23), 8553-8552 (2003)
   PUBMED   14612400
  REMARK    GeneRIF: exhibits a regulated expression during embryogenesis and
            localizes to the nucleus and/or cytoplasm of different cell types
REFERENCE   7  (bases 1 to 5486)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   8  (bases 1 to 5486)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 5486)
  AUTHORS   Zhou,M.I., Wang,H., Ross,J.J., Kuzmin,I., Xu,C. and Cohen,H.T.
  TITLE     The von Hippel-Lindau tumor suppressor stabilizes novel plant
            homeodomain protein Jade-1
  JOURNAL   J Biol Chem 277 (42), 39887-39898 (2002)
   PUBMED   12169691
REFERENCE   10 (bases 1 to 5486)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY060282.1, BN000281.1 and AV515494.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. All four variants encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK049332.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                BY060282.1         1-86
            87-5471             BN000281.1         1-5385
            5472-5486           AV515494.1         294-308
FEATURES             Location/Qualifiers
     source          1..5486
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 19.88 cM"
     gene            1..5486
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /note="jade family PHD finger 1"
                     /db_xref="GeneID:269424"
                     /db_xref="MGI:MGI:1925835"
     exon            1..86
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            87..164
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /inference="alignment:Splign:2.1.0"
     CDS             113..2617
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /note="Jade1 PHD finger protein; PHD finger protein 17;
                     jade family PHD finger protein 1"
                     /codon_start=1
                     /product="protein Jade-1"
                     /protein_id="NP_001123656.1"
                     /db_xref="CCDS:CCDS17331.1"
                     /db_xref="GeneID:269424"
                     /db_xref="MGI:MGI:1925835"
                     /translation="MKRGRLPSSSEDSDDNGSLSTTWSQHSRSQHGRSSTCSRPEDRK
                     PSEVFRTDLITAMKLHDSYQLNPDDYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVV
                     SEEKSLMFIRPKKYIASSGSEPPALGYVDIRTLADSVCRYDLNDMDAAWLEVTNEEFK
                     EMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDG
                     NEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGT
                     KWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNC
                     RTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEEGLGEGAAQENGAPES
                     SPQSPLEPYGSLEPNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDF
                     LYQYWKLKRKINFNKPLITPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTY
                     MVTRREKIKRSVCKVQEQIFTQYTKLLEQEKVSGVPSSCSSALENMLFFNSPSVGPNA
                     PKIEDLKWHSAFFRKQMGTSLVHPLKKSHKRDAVQNSSGTEGKTSHKQPGLCGRREGL
                     EVSESLLSLEKTFAEARLLSSAQQKNGVVTPDHGKRRDNRFHCDLVKGDLKDKSFKQS
                     HKPLRSTDTSQRHLDNTRAATSPGVGQSAPGTRKEIVPKCNGSLVKVPITPASPVKSW
                     GGFRIPKKGERQQQGEAHDGACHQHSDCSHLGVSRAPAKERAKSRLRADSENDGYAPD
                     GEMSDSESEASEKKCIHASSTISRRTDIIRRSILAS"
     exon            165..253
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            254..411
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            412..599
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            600..811
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            812..979
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            980..1096
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1618
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            1619..1736
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            1737..5478
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5446..5451
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /note="hexamer: AATAAA"
     polyA_site      5472
                     /gene="Jade1"
                     /gene_synonym="D530048A03Rik; mKIAA1807; Phf17"
                     /note="major polyA site"
ORIGIN      
        1 tctttgggtt ctagaaggca gaagacatcc ttgtccgctc gcctgctacc tctgaggaaa
       61 ctcggggctc tactcaaagt gctgaggctg cctgctgtct cccggggaga tcatgaaacg
      121 aggtcgcctt cccagcagca gtgaggattc tgacgacaat ggcagcttgt caacgacatg
      181 gtcccagcat tctcgatccc agcatgggag gagtagtacc tgctctagac ctgaagatcg
      241 aaagccttct gaggtgttta ggaccgacct gatcactgcc atgaagttgc atgactccta
      301 ccagctgaac ccggatgact actacgtgct ggctgatccc tggagacagg agtgggagaa
      361 aggggtccag gtgcctgtga gcccagggac catcccacag cctgtggcca gggttgtgtc
      421 tgaagagaag tctctcatgt tcatcaggcc caagaagtac atcgcgtcgt ccggctctga
      481 gcccccagcg ttaggctacg tcgatatccg gactctggca gacagtgtgt gtcggtatga
      541 cctcaatgat atggatgctg cgtggctgga agtaaccaat gaagaattta aggagatggg
      601 gatgccggag ctggacgagt acaccatgga aagggtcttg gaggaattcg aacagcgatg
      661 ctatgacaat atgaatcatg ccatagagac agaagagggc ttggggattg aatacgacga
      721 agacgttgtc tgcgatgtct gccagtcacc tgatggcgag gacggcaacg agatggtgtt
      781 ctgtgacaag tgtaacatct gtgtgcacca ggcttgctat gggatcctca aggtgccaga
      841 gggcagttgg ctatgtcgta catgtgccct gggagttcag ccaaaatgtt tgctgtgtcc
      901 caagaaaggc ggagctatga agccgacccg cagcggaacc aagtgggtcc acgtcagctg
      961 tgccctgtgg atccctgagg taagcattgg cagccctgag aagatggagc ccatcacaaa
     1021 agtgtctcac attcccagca gccggtgggc gcttgtgtgc agcctctgca atgagaaatt
     1081 cggggcctcc atacagtgct ctgtgaagaa ctgccggaca gccttccacg tgacttgtgc
     1141 ttttgaccgt ggcctggaga tgaagaccat attggcagag aatgatgaag tcaaattcaa
     1201 gtcctactgc ccaaagcaca gctcacacag gaaacccgag gagggcctgg gtgaaggagc
     1261 agcccaggag aatggggccc ctgagagttc tccccagagc cctctggagc cctatggtag
     1321 tctggagccg aatcgagagg aggcccaccg ggtgagtgtt cgcaagcaga agctacagca
     1381 gctggaggat gagttctaca cctttgtcaa cctgctggat gtggccaggg cgctgcggct
     1441 gcctgaggaa gtggtggatt tcctgtacca gtactggaag ttgaagagga agatcaactt
     1501 caacaagccc ctcatcaccc caaagaaaga cgaagaggac aatctagcca agcgggagca
     1561 ggatgtcttg tttaggaggc tgcagctgtt cacgcacctg cggcaggacc tggagagggt
     1621 tcggaacctc acttacatgg tgacccgcag ggaaaagatt aaacggtctg tgtgcaaagt
     1681 ccaggaacaa attttcactc agtacactaa gctcttggag caagaaaaag tttcaggtgt
     1741 gccttcttcc tgctcctccg cactggagaa catgcttttt ttcaacagtc cttctgtggg
     1801 ccccaatgct cccaagatag aggacttgaa atggcattct gcattcttca ggaaacaaat
     1861 gggcacttcc ttggttcatc cactgaaaaa gtcccataaa cgagatgcag tgcagaatag
     1921 ttctgggacc gagggcaaga cctcgcataa gcagccaggt ctttgtggta gaagggaggg
     1981 gctggaggtc tcagaaagct tgctgagctt agaaaagact tttgcagaag cacgtctcct
     2041 atcatcagca caacagaaaa atggtgtggt gaccccagac catgggaaaa gaagagacaa
     2101 tcgttttcat tgtgatctcg ttaaaggaga cttaaaggac aaatctttta agcagagtca
     2161 caagcctctc aggtccacag acacatccca gaggcatctg gacaacacaa gagctgccac
     2221 ctcccctgga gtagggcagt cagcacctgg caccaggaag gagattgtgc ccaagtgcaa
     2281 tggctcccta gtcaaagtgc ctataacacc tgccagccca gtgaaaagct ggggaggatt
     2341 ccggattcca aagaaggggg agcggcagca gcaaggagaa gcccatgatg gggcctgcca
     2401 ccagcactca gactgctccc atctgggtgt aagccgagct ccagccaagg agagagcgaa
     2461 gagcaggtta agagctgaca gtgagaatga tgggtacgcc cctgatgggg aaatgagtga
     2521 ctcagagagc gaggcatcag agaagaaatg tatccatgcc agcagcacca tcagcaggag
     2581 gacagatatc atcaggcgaa gcatcttggc ctcttgatga aacagccggt gtggaagcac
     2641 atggcttgtt gccgtgtgct gaggagagct ctgataatag gggcaagcaa atacccattg
     2701 tttctgagct acagacatac ttccttgcaa ttcagattga atttttttcc agagtcattt
     2761 ataaatcatt gtgagaagtt tgtgttattt gcaacttgtt gaggaaacag aagagtagac
     2821 tgtaaccata agacactaag attagaacct gaactaaaca ctataaaaaa aaaaccaaca
     2881 aatgaagtaa ctttgcagag ggccaggctt gaatagcacc atgtattatt gccctctaca
     2941 ttctccccaa agcacaaact cttgaatact cactcttaca gaatcataga attctgtgtg
     3001 gtgaacaagt cctatttcta gaagccctca tgtaccattt atagcccaca aagcttattt
     3061 tctaggaatg gtaaatgctg acggcatttg gctcccaggc tgtgtggtat gaggagctga
     3121 ggttctgaag cttcacaaca ctgggatctt gcacatgtgg catccagggg aagagtttac
     3181 acaacaggca ttgctggaag gctgcaggga cagagcagag ctgctgcact gagatttggg
     3241 gcccgtgtag caaggtcccg aagccctgag tgggctgtgg acacaggacg ggtggaggaa
     3301 aagttgtcca gaaacttctg tgagacaggg cagctgaggc ccaggtgtta ctagtccgct
     3361 tgaccttcct ctttcctaac tgctggcctt tggatccaaa tgggatttcc ctggctactg
     3421 ccagtacttg gccatctggc ttccaataat acaatggtta ttcaagttca agtgatgaac
     3481 ttctggtgac tctcactcta cagagtcaac cactagtgca tatttgggaa atccaggctt
     3541 ccaccatgag tggattcctt aagcaaaaag gaaaacaaaa agcaaaatag gttatatttt
     3601 aaaatataga aaggcaataa gttgcatcaa ggttatacag gaaagaattc aaagtgtatc
     3661 cttgaatagg tttctggagt tggagttcta aactctgatt tgtaacttgg actttcgaat
     3721 tgcaaatggc aataactagt aagttatcag caataataaa tttagcatta aatttgagta
     3781 taatgttctg tttttgcact cctcatatag tgcatatgta ttcagacaag tggatagtgt
     3841 taaagtcctg ttattttctt tggaattcaa tgtagttgtg aatcaaaatt aagagaaggg
     3901 aagtttcatt agcaatgaga tttagaatta agggcatttg gaataagccc agtttcccct
     3961 aaattaccct tagtttatta atatcaatgt tcagattcct gactcattta tacatctgtt
     4021 tccatgtggc agggacattc tgatatttaa tgagcaatgc tttgagtttg tagaagcttt
     4081 caagtcttcc agatgattgt caacaacaga aaaggcttat tgaattccat cttgctatgc
     4141 aagttttatc agatgatcaa atgacagatc tgatgcatct catcgtatgt atgacatttt
     4201 caaactaagt cttaacttct caagtacatt gtagtagcta attcagggga ggggaaagga
     4261 tgacccaggt tttagattga ctattttttg agctatggag ctcctttgag actgctgtcc
     4321 agatcagctc gttgctactg gtattcgaag attctcagga gtccaagttg tacttttgct
     4381 tgtagcctaa tttaaaaatg agatgttttg catctgagca aaaacctttt gctggataca
     4441 ggaaaaggct ggactctgat ctagttatct tttgattaca gcaacagctc tgggtgagaa
     4501 tagaatttat agaggaataa tctgtgaagc catagaaaga aaccctaaat taatctagtg
     4561 agtatatggc ctctcaccat tttaggaggc accagattca tttgcactat taggaatgct
     4621 agttttgtgc aaaaataaat gccttacctg tttcccccca catttaggtt gaaaagcttt
     4681 caaatgttcc aagttatgct gaaccaaaaa caaataaaac aaaatgaaaa aaaaaaaaaa
     4741 aaataataat aaaaaatttc ccccacaaaa acataacaaa aaaaaaaaaa gcccacacgt
     4801 ttaattactg ctttgaaatg caatggtata gagcacggtt tctgacagtg taatgatagc
     4861 tttgtaagtt agttcatgtc atgctgggaa ctctgtatga ggcggccaca ggcagcagca
     4921 gcccacctac ctacccactt gcattctatt agtattgagc ttttttgttt gtttgtttgt
     4981 tcttttgaat cttccttgtg catcctgacc aagaaatatc tttgattatg atcaatgtat
     5041 tatgtcaaaa tgtaggctag ttgaactttt gtaaagttgc ctggaatgtc atttgttagg
     5101 ttataaacac aaaatttaaa tgaagggttt tatgtgttgt gtacaaatct taattatttt
     5161 aaaatggaca gacttgtcat tacatttgta accttgtaca gaggattttt cactatgtgc
     5221 ctagcttggt gtccattcaa ctaaaattga aaaaaaaaag gtgcatgaag agttaaaatc
     5281 agaagttaaa caaagtctat gtagagatga ctattttata ttacatggcc caatcctgta
     5341 tttatttcta cccccttttt gaaagtattt ataaaactag ttgaagacag ctgtattttt
     5401 ttgttgaact atttagtaga atttgtgcct ttttgtctgt atgtgaataa atgctgtaca
     5461 ttttgcaata cattttaaaa aaaaaa
//
