LOCUS       NM_001362459            3986 bp    mRNA    linear   ROD 24-DEC-2022
DEFINITION  Mus musculus inositol 1,4,5-triphosphate receptor interacting
            protein (Itprip), transcript variant 3, mRNA.
ACCESSION   NM_001362459 XM_006527175
VERSION     NM_001362459.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3986)
  AUTHORS   Cheng LC, Baboo S, Lindsay C, Brusman L, Martinez-Bartolome S,
            Tapia O, Zhang X, Yates JR 3rd and Gerace L.
  TITLE     Identification of new transmembrane proteins concentrated at the
            nuclear envelope using organellar proteomics of mesenchymal cells
  JOURNAL   Nucleus 10 (1), 126-143 (2019)
   PUBMED   31142202
REFERENCE   2  (bases 1 to 3986)
  AUTHORS   Liu Q, Tian Y, Zhao X, Jing H, Xie Q, Li P, Li D, Yan D and Zhu X.
  TITLE     NMAAP1 Expressed in BCG-Activated Macrophage Promotes M1 Macrophage
            Polarization
  JOURNAL   Mol Cells 38 (10), 886-894 (2015)
   PUBMED   26429502
  REMARK    GeneRIF: Novel Macrophage Activated Associated Protein 1
            NP_001001738) is an essential molecule that modulates macrophages
            phenotype and plays an important role in macrophage tumoricidal
            functions
REFERENCE   3  (bases 1 to 3986)
  AUTHORS   Kang BN, Ahmad AS, Saleem S, Patterson RL, Hester L, Dore S and
            Snyder SH.
  TITLE     Death-associated protein kinase-mediated cell death modulated by
            interaction with DANGER
  JOURNAL   J Neurosci 30 (1), 93-98 (2010)
   PUBMED   20053891
  REMARK    GeneRIF: DANGER-deficient mouse embryonic fibroblasts and neurons
            exhibit greater death-associated protein kinase activity and
            increased sensitivity to cell death.
REFERENCE   4  (bases 1 to 3986)
  AUTHORS   Piao Y, Ko NT, Lim MK and Ko MS.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC126679.2.
            
            [WARNING] On May 16, 2023 this sequence was replaced by
            NM_001362459.2.
            
            On Apr 18, 2018 this sequence version replaced XM_006527175.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13948564.552504.1,
                                           SRR17253011.4961909.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849379, SAMN00849388
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-200               AC126679.2         81965-82164
            201-385             AC126679.2         86688-86872
            386-3986            AC126679.2         103098-106698
FEATURES             Location/Qualifiers
     source          1..3986
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19"
     gene            1..3986
                     /gene="Itprip"
                     /gene_synonym="4833424O12Rik; DANGER"
                     /note="inositol 1,4,5-triphosphate receptor interacting
                     protein"
                     /db_xref="GeneID:414801"
                     /db_xref="MGI:MGI:3042776"
     exon            1..200
                     /gene="Itprip"
                     /gene_synonym="4833424O12Rik; DANGER"
                     /inference="alignment:Splign:2.1.0"
     exon            201..385
                     /gene="Itprip"
                     /gene_synonym="4833424O12Rik; DANGER"
                     /inference="alignment:Splign:2.1.0"
     exon            386..3986
                     /gene="Itprip"
                     /gene_synonym="4833424O12Rik; DANGER"
                     /inference="alignment:Splign:2.1.0"
     CDS             402..2069
                     /gene="Itprip"
                     /gene_synonym="4833424O12Rik; DANGER"
                     /note="inositol 1,4,5-trisphosphate receptor-interacting
                     protein"
                     /codon_start=1
                     /product="inositol 1,4,5-trisphosphate
                     receptor-interacting protein precursor"
                     /protein_id="NP_001349388.1"
                     /db_xref="CCDS:CCDS29895.1"
                     /db_xref="GeneID:414801"
                     /db_xref="MGI:MGI:3042776"
                     /translation="MAMELFRVCLVVVTAIINHPLLFPRENATIPENEEEIIRKMQEH
                     QEKLRLEQLRLEEEVSRLEAEKEALRQVEEEQQQLEAHTAWDLWTTLCMVLFLIIEVL
                     RQNHQEGTFPECLGGDEDELSGLGGTLLQGLPLPNRATLDHFYEHCIRSTTGDATRTQ
                     EFVEGFVDDLLEALRSTYNGKTDMELEDFIGVGSMYENWQVERPLRCHLFIPFIPPEP
                     YSFHPEFWCSSLSTPLERQGYGQIKVTLADGNPLGCVCGKAKLEEDMLCLLYGKNRGA
                     WPSSAGCGEMEGLLCSRESSYLDVMQVMKWFQMALTRAWHRIAHKYEFDLAFGELDTP
                     GSLKIKFRSGKSMPFILTPVIQCNDSDLYFILQLPKEPCGGGPASSAHWLLSFAVYER
                     EFLRMTGKALPEGACHLSCLQIASFLLSKQTRLTGPSGLSDYHLKTALLHLLLSRQAS
                     DWKASKLDVRLQDLFCFLERSLLEKKLYHFFMGNHKVPEALGLPEVVRRAEPLNLFRP
                     FVLQRTLYRNTVDSFYEMLKNAPALISEYSLHVPSVRASPPPKAVVS"
ORIGIN      
        1 ggagcaaaaa gtttccgtga caacgcggaa atgagtaact ctgttgccca gtaaagctgg
       61 gcgggaggag tccaggaggc gggagccgcc ttggtctagt cgcccgcatc cctggatccc
      121 cggcagcctg cagacccggg accacgaccc gcgcttggag cgaggcccac tcggtatccc
      181 tgcggcggcc gcggccgaac agaatatgtc ttctctgtgc ccatgtgtcc cacccggtga
      241 catcattgga atggaggccc ctcagatggc attactgttg cccaggtaac acctccacct
      301 taaggcagac aggaaggaca tataccagca tcaactgtaa gacgcatgtt ccaggaaagg
      361 accctagaag atataactac cacaggacag agactgcagc tatggccatg gaactcttcc
      421 gggtctgtct ggtcgtggtg acagccatca ttaaccaccc tctgctgttc ccacgggaga
      481 atgccacgat tcccgagaac gaggaagaga tcatacgcaa gatgcaggag caccaggaga
      541 agctgcgcct ggagcagcta cgcctggagg aggaggtgtc acgtctggag gccgagaagg
      601 aggctctgcg gcaggtggag gaggagcagc agcagctaga ggcccacacc gcctgggacc
      661 tctggaccac actctgcatg gtcctcttcc tgatcatcga ggtgttgcga cagaaccatc
      721 aggagggcac cttcccggag tgcctgggtg gagacgagga cgagctgtcg ggactagggg
      781 gcacgctgct gcagggcctt cccctgccca atagggccac cctggaccac ttctacgagc
      841 actgtatccg gagcaccacg ggggatgcca cccgcaccca ggagtttgtg gaaggtttcg
      901 tggatgatct gctggaagcc ctgaggagca cctacaacgg gaaaaccgac atggaattgg
      961 aggacttcat cggcgtgggc agcatgtatg agaactggca agtggagagg ccactacggt
     1021 gccacttgtt tatacccttc atacccccag agccctacag cttccaccca gagttctggt
     1081 gctccagcct ttcaacgccc ctggaacgtc agggctatgg ccagatcaag gtgacgctgg
     1141 ctgacgggaa ccctctaggc tgtgtctgcg gcaaggctaa gcttgaggag gatatgttgt
     1201 gtctcctcta cggcaagaat agaggggcgt ggcccagcag tgccgggtgc ggtgagatgg
     1261 agggcttgct gtgttccaga gagtcctcct atctcgatgt catgcaggtc atgaagtggt
     1321 ttcagatggc cctcaccaga gcgtggcacc gcatcgccca caagtatgag tttgaccttg
     1381 cctttggaga gctggacacc ccagggtctc tcaaaatcaa gttccgctcg gggaagtcca
     1441 tgcctttcat cttgactcct gtgatccagt gtaatgactc agacctgtac ttcatcttac
     1501 aacttcccaa ggagccctgt gggggaggcc cagcctccag cgctcactgg ctcctgtcct
     1561 ttgctgtcta tgagcgagag ttcctccgga tgacaggcaa ggctttgccg gagggtgcct
     1621 gccacctgag ctgtttgcag atcgcctcct tcttgctctc caagcagacc cgtctgacgg
     1681 gtcccagtgg gctgagtgac taccacctaa agactgccct gctgcatctc ctgctgtccc
     1741 ggcaggcctc tgactggaag gccagcaagc tggatgtacg cctgcaggac ctcttctgct
     1801 tcctggagag gagcctgctg gagaagaaac tctatcactt cttcatgggc aaccacaagg
     1861 tgcctgaggc tctgggtctc ccagaggttg tgcgcagagc cgagcctctc aatctcttcc
     1921 ggcccttcgt cttgcagcgg actctttacc ggaacacagt ggactccttc tatgaaatgc
     1981 ttaagaacgc cccggcgctc attagcgagt attccctcca tgtcccttca gttcgtgcca
     2041 gcccaccacc aaaagctgtc gtctcgtaat agtttaagat ttgggggttg aggagggaga
     2101 gccatcccgt gcgtcgacct tcctgggccc tgtgacctca cacaggaaac acagtagatc
     2161 tagagggagc cgaggctcag tttcccagga agccaggccc tacagagtga aggaaacaag
     2221 agttacaact agacgctggt ttgcctttcc gccacggggg cttgttggta aaaccattgt
     2281 ttgggtttgg gtaccaatcg tttgtagctt agttttagat cactatgaac ggccaagaca
     2341 gtgaccacac agtctctagg gtactgagtt agagagagcg caagcactga ccagaatgca
     2401 gtcctttctg tagcatagtc cgttctgtgt tccatagcaa agaggagcta ccaggatggt
     2461 gctggggatc tgagacccag cactgcaccc caggcgttcc aggccccagc catctgcaga
     2521 tgaatcttga atggggacag atgtgggaat tcacagcctt ggaaccgcat cgtgcacagt
     2581 aatagaggtc ccacagtggc tgagttggct aaaagaacct gccagaaggc taggggcctg
     2641 gtggctaatg tctccactac agagaagtgg ggccttggtg gtggagtgtc taaagctggc
     2701 cagtttctca ggcacacatc ttactcaggt gcatcccctg ctgctctacc cttgtatggg
     2761 gtcccaatca cagtgggtgc catttaccac actgggtgct ggcccagaag cccctctcct
     2821 ctctccgttg ctggtcttac cagccagcag tatggcagaa ggacacaggg acaaagttcg
     2881 acccactttg aggaaagcta gagatccctg ggacaagggt taggatatct ctaacccatc
     2941 ttggggtcct ggtcataggg aaaggtgagc ttataagcca caggcactat gaaaacccag
     3001 ctctggtcct cggaccccga gcatctccca gttcctaatg ccaagagggc ctcacccagt
     3061 gcctccagtc ttttctgcac acgccatggt gacctcgtag ctgacccaga cttaaagaag
     3121 gtggtagagg ctgggctcac tggggatcta tatgagtcgt tcaagcatag cctggttacc
     3181 caaaggagcg ttgtgagccc cagacaagac cagagcctga ggctggactc caggacccag
     3241 cagcttcttt tccacttgac cttgactgtc tgtttgggat ttcttcgcca catctcctta
     3301 ggaactttta cagtgggcca aagaagaaac agtaagaaag aggtagcgcc tgctagcctt
     3361 ccagaagtgc aggcatcaaa atcaggcttc ccttcgcccc acacgtgcct cctgtggtct
     3421 caaagctctc cagaagatag acgattttgc caccagggtt aagtggtggt ggagaggatc
     3481 tgctgggtgc acagaagcca gaggcaatag gatacttgag taccggcggt gggggttaaa
     3541 ctgagcatgc gcggtcctgc ccctccgcag ctccaattgt caccctagca cccagtcatg
     3601 gagcctactc aatgtgcagc tctgtcaaca gccctaagcc gcctcacccg agaggtacct
     3661 tccagagggg aggcagatgt cctcattgtc acctgtgcct ttcctggctc actcatatcc
     3721 ggctgtgttt ccaggagtgc ccggcaacca agaaccagcc tccagaagcc aagacccaac
     3781 ctgagcctcc ttcagcttcc ccttcgcttc cagggaaaga tcacgggaag gccatgggca
     3841 gaacatcagt ggctccttgt ctgctgagca cccgggcagg acaggagact gtcccacacc
     3901 agggctgctt tggaagcagc agggctctta ggggttcatg ctgccttgtt tgtattaaaa
     3961 gaagaattaa attcttgtaa ggagta
//
