LOCUS       NM_010585               9877 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Mus musculus inositol 1,4,5-trisphosphate receptor 1 (Itpr1), mRNA.
ACCESSION   NM_010585 NM_008789
VERSION     NM_010585.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9877)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 9877)
  AUTHORS   Akizawa,H., Lopes,E.M. and Fissore,R.A.
  TITLE     Zn2+ is essential for Ca2+ oscillations in mouse eggs
  JOURNAL   Elife 12, 88082 (2023)
   PUBMED   38099643
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9877)
  AUTHORS   Dong,S., Wu,Y., Zhang,Y., Li,S., Zhao,Q., Liu,S., Guo,Y., Li,X.,
            Song,K., Wu,L., Wu,L., Shi,J., Gong,L. and Yu,J.
  TITLE     IP3R-1 aggravates endotoxin-induced acute lung injury in mice by
            regulating MAM formation and mitochondrial function
  JOURNAL   Exp Biol Med (Maywood) 248 (23), 2262-2272 (2023)
   PUBMED   38159072
  REMARK    GeneRIF: IP3R-1 aggravates endotoxin-induced acute lung injury in
            mice by regulating MAM formation and mitochondrial function.
REFERENCE   4  (bases 1 to 9877)
  AUTHORS   Bosanac,I., Alattia,J.R., Mal,T.K., Chan,J., Talarico,S.,
            Tong,F.K., Tong,K.I., Yoshikawa,F., Furuichi,T., Iwai,M.,
            Michikawa,T., Mikoshiba,K. and Ikura,M.
  TITLE     Structure of the inositol 1,4,5-trisphosphate receptor binding core
            in complex with its ligand
  JOURNAL   Nature 420 (6916), 696-700 (2002)
   PUBMED   12442173
  REMARK    GeneRIF: crystal structure of the inositol 1,4,5-trisphosphate
            receptor binding core in complex with its ligand
REFERENCE   5  (bases 1 to 9877)
  AUTHORS   Harnick,D.J., Jayaraman,T., Ma,Y., Mulieri,P., Go,L.O. and
            Marks,A.R.
  TITLE     The human type 1 inositol 1,4,5-trisphosphate receptor from T
            lymphocytes. Structure, localization, and tyrosine phosphorylation
  JOURNAL   J Biol Chem 270 (6), 2833-2840 (1995)
   PUBMED   7852357
REFERENCE   6  (bases 1 to 9877)
  AUTHORS   Yamada,N., Makino,Y., Clark,R.A., Pearson,D.W., Mattei,M.G.,
            Guenet,J.L., Ohama,E., Fujino,I., Miyawaki,A., Furuichi,T. et al.
  TITLE     Human inositol 1,4,5-trisphosphate type-1 receptor, InsP3R1:
            structure, function, regulation of expression and chromosomal
            localization
  JOURNAL   Biochem J 302 (Pt 3) (Pt 3), 781-790 (1994)
   PUBMED   7945203
REFERENCE   7  (bases 1 to 9877)
  AUTHORS   Ross,C.A., Danoff,S.K., Schell,M.J., Snyder,S.H. and Ullrich,A.
  TITLE     Three additional inositol 1,4,5-trisphosphate receptors: molecular
            cloning and differential localization in brain and peripheral
            tissues
  JOURNAL   Proc Natl Acad Sci U S A 89 (10), 4265-4269 (1992)
   PUBMED   1374893
REFERENCE   8  (bases 1 to 9877)
  AUTHORS   Nakagawa,T., Okano,H., Furuichi,T., Aruga,J. and Mikoshiba,K.
  TITLE     The subtypes of the mouse inositol 1,4,5-trisphosphate receptor are
            expressed in a tissue-specific and developmentally specific manner
  JOURNAL   Proc Natl Acad Sci U S A 88 (14), 6244-6248 (1991)
   PUBMED   1648733
REFERENCE   9  (bases 1 to 9877)
  AUTHORS   Norman,D.J., Fletcher,C. and Heintz,N.
  TITLE     Genetic mapping of the lurcher locus on mouse chromosome 6 using an
            intersubspecific backcross
  JOURNAL   Genomics 9 (1), 147-153 (1991)
   PUBMED   1672287
REFERENCE   10 (bases 1 to 9877)
  AUTHORS   Mikoshiba,K., Furuichi,T., Maeda,N., Yoshikawa,S., Miyawaki,A.,
            Niinobe,M. and Wada,K.
  TITLE     Primary structure and functional expression of the inositol
            1,4,5-trisphosphate receptor, P400
  JOURNAL   Adv Exp Med Biol 287, 83-95 (1991)
   PUBMED   1662017
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK047719.1, AK049015.1, AK137477.1, CF539692.1, DN176734.1,
            BU705754.1, CF744794.1, CB521690.1, CF168791.1, CK636937.1,
            CN459019.1, AC156506.4, CN692248.1, DV652411.1, M21530.1,
            AK044776.1 and CJ236273.1.
            
            On Dec 1, 2011 this sequence version replaced NM_010585.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X15373.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1392              AK047719.1         2-1393
            1393-1601           AK049015.1         1007-1215
            1602-3804           AK137477.1         1604-3806
            3805-4140           CF539692.1         300-635
            4141-4565           DN176734.1         97-521
            4566-4887           BU705754.1         13-334
            4888-5423           CF744794.1         153-688
            5424-5492           CB521690.1         277-345
            5493-5738           CF168791.1         415-660
            5739-6295           CK636937.1         137-693
            6296-6710           CN459019.1         101-515
            6711-6833           AC156506.4         51821-51943
            6834-6938           AC156506.4         53150-53254
            6939-7131           AC156506.4         57036-57228
            7132-7551           CN692248.1         185-604
            7552-7884           DV652411.1         148-480
            7885-9070           M21530.1           788-1973
            9071-9840           AK044776.1         1864-2633
            9841-9877           CJ236273.1         635-671
FEATURES             Location/Qualifiers
     source          1..9877
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 49.74 cM"
     gene            1..9877
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /note="inositol 1,4,5-trisphosphate receptor 1"
                     /db_xref="GeneID:16438"
                     /db_xref="MGI:MGI:96623"
     exon            1..258
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            259..334
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            335..442
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     CDS             351..8600
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /note="Purkinje cell protein 1; inositol
                     1,4,5-trisphosphate receptor type 1; type 1 inositol
                     1,4,5-trisphosphate receptor; protein PCD-6; type 1 InsP3
                     receptor; IP3 receptor; inositol
                     1,4,5-trisphosphate-binding protein P400; opisthotonus;
                     InsP>3<R type I; inositol 1,4,5 trisphosphate receptor"
                     /codon_start=1
                     /product="inositol 1,4,5-trisphosphate-gated calcium
                     channel ITPR1"
                     /protein_id="NP_034715.3"
                     /db_xref="CCDS:CCDS51869.1"
                     /db_xref="GeneID:16438"
                     /db_xref="MGI:MGI:96623"
                     /translation="MSDKMSSFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPEAG
                     DLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQ
                     NETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSW
                     FYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSW
                     KIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSAT
                     SSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVD
                     PDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRH
                     LCTNTWVHSTNIPIDKEEEKPVMLKIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDAS
                     KVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQK
                     LMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQD
                     YRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRK
                     NREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVST
                     GENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDILSYYRYQLNLF
                     ARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQV
                     TPVKYARLWSEIPSEIAIDDYDSSGTSKDEIKERFAQTMEFVEEYLRDVVCQRFPFSD
                     KEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMTKGEE
                     NKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKL
                     KIIEILQFILNVRLDYRISCLLCIFKREFDESNSQSSETSSGNSSQEGPSNVPGALDF
                     EHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFS
                     QRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGPDEPMDGA
                     SGENEHKKTEEGTSKPLKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRL
                     LRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLF
                     LNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEG
                     KFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLV
                     ELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVE
                     MKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPF
                     SDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPV
                     DLDSQVNNLFLKSHNIVQKTALNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSAL
                     EDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEE
                     KLCIKVLQTLREMMTKDRGYGEKQISIDESENAELPQAPEAENSTEQELEPSPPLRQL
                     EDHKRGEALRQILVNRYYGNIRPSGRRESLTSFGNGPLSPGGPSKPGGGGGGPGSSST
                     SRGEMSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSF
                     FCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKA
                     KEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQSGEGTQATTDKAKDDLEM
                     SAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGG
                     LGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDIN
                     PLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGE
                     VEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQTMLKPGGQVDGDEALEFYAK
                     HTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSED
                     LFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEP
                     HWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNK
                     IIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLLICAMGLFVHEFFYSLLLFDLVYR
                     EETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVP
                     ETGESLANDFLYSDVCRVETGENCTSPAPKEELLPAEETEQDKEHTCETLLMCIVTVL
                     SHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLR
                     SEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTE
                     YTGPESYVAEMIRERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLS
                     GQLSELKDQMTEQRKQKQRIGLLGHPPHMNVNPQQPA"
     exon            443..513
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            514..629
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            630..716
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            717..875
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            876..974
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            975..1058
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1205
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            1206..1301
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1346
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..1501
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            1502..1601
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            1602..1762
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..1904
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            1905..2063
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            2064..2236
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            2237..2356
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            2357..2551
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            2552..2803
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            2804..2945
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            2946..3099
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            3100..3287
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            3288..3426
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            3427..3481
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            3482..3647
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            3648..3818
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            3819..3884
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            3885..4022
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            4023..4148
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            4149..4349
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            4350..4601
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            4602..4727
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            4728..4856
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            4857..4977
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            4978..5162
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            5163..5311
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            5312..5423
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            5424..5456
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            5457..5492
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            5493..5543
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            5544..5676
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            5677..5867
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            5868..6048
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            6049..6302
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            6303..6503
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            6504..6614
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            6615..6710
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            6711..6833
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            6834..6938
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            6939..7131
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            7132..7254
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            7255..7430
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            7431..7595
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            7596..7791
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            7792..7884
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            7885..8024
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            8025..8190
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            8191..8351
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            8352..8513
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     exon            8514..9877
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9851..9856
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /note="hexamer: AATAAA"
     polyA_site      9871
                     /gene="Itpr1"
                     /gene_synonym="D6Pas2; Gm10429; InsP3R; insP3R1; Ip3r;
                     IP3R 1; IP3R1; Itpr-1; opt; P400; Pcp-1; Pcp1; wblo"
                     /note="major polyA site"
ORIGIN      
        1 gcagtaacca tgtggatgtt ctgctgaagc gtttcctcaa gcctgccggg gtgggaggag
       61 aggaggaggt ggtggtggtg gaggaggtgg aggcagaggg tggagagaga gaaagcgcac
      121 gccgagagga ggtgtgggtg ttccgctccc atcctaacgg aacgagctcc ctcttcgcgg
      181 acatgggatt gcccagcggc tgctaacccc tctcctggtc ctgatccccc aaaccggcgt
      241 ggctccccgg tcaccaagga gctgattaca agggaccagg atttgcatcc ttggctgggc
      301 gtccattggc tacagagtgc ctgacctggg tcaggctttc caacacggac atgtctgaca
      361 aaatgtcgag tttcctacat attggagaca tttgttctct gtatgcggag ggatctacga
      421 atggatttat cagcacctta ggcttggttg atgaccgttg tgttgtacag ccagaagccg
      481 gggaccttaa caatccaccc aagaaattca gagactgcct ctttaagcta tgtcctatga
      541 atcgatactc cgcacagaaa cagttctgga aagctgctaa gcccggggcc aacagcacta
      601 cagatgcagt gctgctcaac aaattgcatc atgctgcaga cttggaaaag aagcagaatg
      661 agacagaaaa caggaaattg ttggggaccg tcatccaata tggcaacgtg atccagctcc
      721 tgcatttgaa aagcaataaa tacctgactg tgaataagag gctcccagcc ttgctagaga
      781 agaacgccat gagggtgacg ttggacgagg ctggaaatga agggtcctgg ttttacattc
      841 aaccattcta caagcttcgc tccatcggag acagtgtggt cataggcgac aaggtagttt
      901 tgaatcctgt caatgctggc cagcctctac atgccagcag tcatcagctg gtggataacc
      961 caggctgcaa tgaggtcaac tccgtcaact gtaatacaag ctggaagata gtgcttttca
     1021 tgaaatggag tgataacaaa gacgatattc tcaaaggagg tgatgtggtg aggctcttcc
     1081 atgccgagca agagaagttt ctcacctgcg atgagcaccg gaagaagcag catgtgttcc
     1141 tgaggaccac cggcaggcag tcagccacat cggccaccag ttccaaagcc ctgtgggaag
     1201 tggaggtagt ccagcacgac ccatgtcggg gtggagctgg gtactggaat agcctcttcc
     1261 ggttcaagca cctggctaca gggcattact tggctgcaga ggtagaccct gactttgagg
     1321 aagaatgcct ggagtttcag ccctcagtgg accctgatca ggatgcatct cggagtaggt
     1381 tgagaaacgc gcaagaaaaa atggtatact ctctggtctc cgtgcctgaa ggcaacgaca
     1441 tctcctccat ctttgagcta gaccccacga ctctgcgtgg aggtgacagc cttgtcccaa
     1501 ggaactccta tgtccgtctc agacacctgt gcaccaacac ctgggtacac agcacaaaca
     1561 tccccatcga caaggaagag gagaagcctg tgatgctgaa aattggtacc tctcccctga
     1621 aggaggacaa ggaagcattt gccatagttc ctgtttcccc tgctgaggtt cgggacctgg
     1681 actttgccaa tgatgccagc aaggtgctgg gctccatcgc tgggaagttg gaaaagggca
     1741 caatcaccca gaatgagaga aggtctgtca cgaagctttt ggaagacttg gtttactttg
     1801 tcacgggtgg aactaactct ggccaagacg tgcttgaagt tgtcttctct aagcccaatc
     1861 gagagcggca gaagctgatg agggaacaga atattctcaa gcagatcttc aagctgttgc
     1921 aggccccctt cacggactgc ggggatggcc cgatgcttcg gctggaggag ctgggggatc
     1981 agcgccatgc tcctttcaga catatttgcc gactctgcta cagggtcctg cgacactcac
     2041 agcaagacta caggaagaac caggagtaca tagccaagca gtttggcttc atgcagaagc
     2101 agattggcta tgacgtgctg gccgaagaca ccatcactgc cctgctccac aacaaccgga
     2161 aactcctgga gaagcacatc accgcggcag agattgacac gtttgtcagc ctggtgcgaa
     2221 agaacaggga gcccaggttc ttggattacc tctctgacct ctgcgtatcc atgaacaagt
     2281 caatccctgt gacacaggag ctcatctgta aagctgtgct caatcccacc aatgctgaca
     2341 tcctgattga gaccaagctg gttctttctc gttttgagtt tgaaggcgtt tccactggag
     2401 agaatgctct ggaagccggg gaggatgagg aagaggtgtg gctgttctgg agggacagca
     2461 acaaagagat ccgtagtaag agtgtccggg aattggcgca agatgctaaa gagggacaga
     2521 aggaagacag ggacatcctc agctactaca gatatcagct gaacctcttt gcaaggatgt
     2581 gtctggaccg ccagtacctg gccatcaatg aaatctccgg gcagctggat gttgatctca
     2641 ttctccgctg catgtctgac gagaacctcc cctacgacct cagggcatcc ttttgccgcc
     2701 tcatgcttca catgcatgtg gaccgagatc cccaagagca ggtgacacct gtgaaatatg
     2761 cccgactgtg gtcagaaatt ccctctgaga tcgccattga tgactatgac agcagtggaa
     2821 catccaaaga tgaaattaag gagaggtttg cacagacgat ggagtttgtg gaggagtacc
     2881 taagagatgt ggtttgtcaa agattcccct tctctgataa ggagaaaaat aagctcacgt
     2941 ttgaggttgt gaacttagcc aggaatctca tatactttgg tttctacaac ttttctgacc
     3001 ttctccgatt aaccaagatc ctcttggcaa tcttagactg tgtccatgtg accactatct
     3061 tccccattag caagatgaca aaaggagaag agaataaagg cagtaacgtg atgaggtcta
     3121 tccatggcgt tggggagctg atgacccagg tggtgctgcg gggaggaggc ttcttgccca
     3181 tgactcccat ggctgcggcc cctgaaggaa atgtgaagca ggcagagcca gagaaagagg
     3241 acatcatggt catggacacc aagttgaaga tcattgaaat actccagttt attttgaatg
     3301 tgagattgga ttataggatc tcctgcctcc tgtgtatatt taagcgagag tttgatgaaa
     3361 gcaattccca gtcatcagaa acatcctccg gaaacagcag ccaggaaggg ccaagtaatg
     3421 tgccaggtgc tcttgacttt gaacacattg aagaacaagc ggaaggcatc tttggaggaa
     3481 gtgaggagaa cacacctttg gacctggatg accatggtgg cagaaccttc ctcagggtcc
     3541 tgctccactt gacaatgcat gactacccac ccctggtgtc tggggccctg cagctcctct
     3601 ttcggcactt cagccagagg caggaggtcc ttcaggcctt caaacaggtt caactgctgg
     3661 ttactagcca agatgtggac aactacaaac agatcaagca agacttggac caactaaggt
     3721 ccattgtgga gaagtctgag ctctgggtgt acaaaggcca aggtcccgat gagcctatgg
     3781 acggagcctc cggtgaaaat gagcataaga aaaccgagga ggggacgagc aagccactga
     3841 agcacgagag caccagcagc tacaactacc gagtggtgaa agagattttg attcgactta
     3901 gcaagctctg cgtgcaggag agcgcgtcgg tgaggaagag ccggaagcag cagcaacgac
     3961 tgctgaggaa catgggcgca cacgctgtgg tgctggagct gctgcagatc ccctacgaga
     4021 aggccgaaga cacaaagatg caagagatca tgcggctggc tcatgaattt ttgcagaatt
     4081 tctgtgcagg caaccagcag aatcaagctt tgctgcataa acacataaac ctgtttctca
     4141 acccagggat cctggaggca gtgacgatgc agcacatctt catgaacaac ttccagctgt
     4201 gcagtgagat caacgagaga gtggtccagc actttgttca ctgcatagag acccacggtc
     4261 gaaacgtcca gtatatcaag tttctccaga cgattgtcaa ggcagaaggg aaattcatta
     4321 aaaagtgcca agacatggtc atggctgagc ttgtcaactc tggagaggac gtcctcgtgt
     4381 tctacaatga cagagcctct ttccagactc tgatccagat gatgcggtcc gagcgtgacc
     4441 ggatggatga gaacagccct ctcatgtacc acatccatct ggtggagctc ttggccgtgt
     4501 gcacagaggg caagaatgtg tacacggaga tcaagtgcaa ctccttgctc ccgctcgatg
     4561 acatcgttcg tgtggtcact catgaagact gcatccccga ggttaagatc gcttacatta
     4621 acttcctgaa tcactgctat gtggatacgg aggtggagat gaaggagatt tacacaagca
     4681 accacatgtg gaagttgttt gagaatttcc tcgtggacat ctgcagggcc tgtaacaaca
     4741 caagcgacag gaagcacgca gactccattc tggagaagta cgtcactgaa atcgtgatga
     4801 gcatcgtcac caccttcttc agctctccct tctcagacca gagcaccact ctgcagaccc
     4861 gccagcctgt ctttgtgcaa ctcctgcaag gcgtgttccg agtttaccac tgcaactggc
     4921 tgatgccgag ccaaaaagcc tcggtggaga gctgcatccg ggtgctctct gacgtagcca
     4981 agagccgggc catagccatt cctgttgacc tggacagcca agtcaacaac ctcttcctga
     5041 agtcccacaa cattgtgcag aaaacagccc tgaactggcg gttatcagcc cgaaacgccg
     5101 ctcgcagaga ctctgtactg gcagcatcca gagactaccg aaatatcatt gagaggttac
     5161 aggacatcgt gtctgcccta gaggaccggc tcaggcccct ggtgcaggct gagctgtctg
     5221 tgctcgtgga tgttctacac agaccagaac tgctcttccc cgagaacacg gatgccagga
     5281 ggaaatgtga gagtggaggt ttcatctgca agctaataaa acataccaag caactgctgg
     5341 aggagaatga agagaaacta tgcattaaag tcttacagac cctcagggaa atgatgacca
     5401 aagacagagg ctatggagag aagcaaattt ccattgatga atcggaaaat gccgagctgc
     5461 cacaggcacc ggaagctgag aactccacag agcaggagct tgaaccaagt ccacccctga
     5521 ggcaactgga agaccataaa aggggtgagg cactccgaca aattttggtc aaccgttact
     5581 atggaaacat cagaccttca ggaagaagag agagccttac cagctttggc aatggcccac
     5641 tatcaccagg aggacccagc aagcctggtg gaggaggggg aggtcctgga tctagttcca
     5701 caagcagggg tgagatgagc ctggctgagg ttcagtgtca cctcgacaag gagggggcct
     5761 ccaacctggt catcgatctc ataatgaatg catccagtga ccgagtattc catgaaagca
     5821 ttctgctggc catcgcactt ctggaaggag gcaacaccac catccagcac tcgtttttct
     5881 gccggctgac agaagataag aaatcagaga agttcttcaa ggttttttac gatcgaatga
     5941 aggtggccca gcaggaaatc aaggcgacag tgacagtgaa caccagcgac ttgggaaaca
     6001 aaaagaaaga tgatgaagtg gacagggatg ccccgtctcg gaagaaagcc aaagagccca
     6061 caacacagat aacagaagag gtccgggatc agctcctgga agcatctgct gccaccagga
     6121 aagcctttac caccttccgg agggaggccg accctgatga ccattaccag tctggggagg
     6181 gcacccaggc tacaaccgac aaagccaagg atgacctaga gatgagcgct gtcatcacca
     6241 tcatgcagcc tatcctgcgc ttcctgcagc tgctgtgtga aaaccacaac cgagatctgc
     6301 agaatttcct tcgttgccaa aataataaga ccaactacaa tttggtgtgt gagacactgc
     6361 agtttctgga ctgtatttgt gggagcacaa ccggaggcct tggtcttctt ggactgtaca
     6421 taaatgaaaa gaatgtagca cttatcaacc aaaccctgga gagtctgacg gagtactgtc
     6481 aagggccttg ccatgagaac cagaactgca tcgccaccca cgagtccaat ggcatcgata
     6541 tcatcacagc cctcatcctc aatgatatca accctctggg aaagaagcgg atggacctgg
     6601 tgttagaact gaagaacaat gcttcgaagc tgctactggc catcatggaa agcagacacg
     6661 atagtgaaaa tgcagagagg atcctgtaca acatgaggcc caaggagctg gtggaagtga
     6721 tcaagaaggc ctacatgcaa ggtgaagtgg aatttgagga tggggagaac ggtgaggatg
     6781 gagctgcctc acccaggaac gtgggccaca acatctacat cctcgctcac cagttggctc
     6841 ggcataacaa agaacttcaa accatgctga aacctggagg ccaggtggat ggggatgaag
     6901 ctctggagtt ctacgcgaag cacacagcac aaattgagat tgtcagactg gaccggacaa
     6961 tggaacagat cgtcttccct gtgcccagca tctgtgaatt cctgactaag gaatcgaaac
     7021 ttcgaatata ttacaccaca gagcgggatg agcaaggtag caagatcaat gacttcttcc
     7081 tgcgctccga ggacctcttt aacgagatga actggcagaa gaaacttcga gcccagcctg
     7141 tcttgtactg gtgtgcccga aacatgtctt tctggagcag catctccttc aacctggccg
     7201 tcctgatgaa cctgctggtg gcgtttttct atccatttaa aggagtaagg ggaggaacac
     7261 tagagccaca ctggtcaggc cttctgtgga cagccatgct catctctctg gccattgtca
     7321 ttgctctgcc caagccccac ggcatccggg ccttaattgc ttctacaatc ctacgactga
     7381 tattttcagt tgggttgcag cccacactgt ttctgctggg agctttcaat gtctgcaata
     7441 aaatcatctt cctgatgagc tttgtgggca actgtgggac cttcaccaga ggctaccggg
     7501 ccatggttct ggatgtggag ttcctctatc atttgctgta tctactcatc tgtgccatgg
     7561 gcctcttcgt acatgagttc ttctatagct tgctgctttt tgatttagtg tacagagagg
     7621 agactttgct taatgtcatt aaaagtgtca cccgcaatgg acggtccatc atcttgacag
     7681 cggtcctggc tctgatcctg gtttacctgt tctcaattgt gggctatctg ttcttcaagg
     7741 atgactttat cttggaagta gataggttgc ccaatgaaac agctgttcca gaaactggcg
     7801 agagtttggc caacgatttc ctgtactctg atgtgtgcag ggtagagacg ggggagaact
     7861 gcacctctcc tgcacccaaa gaagagctgc tccctgccga agaaacggaa caggataagg
     7921 aacacacgtg tgagaccctg ctcatgtgca tcgtcactgt tctgagtcac gggctgcgga
     7981 gtgggggagg ggtaggagac gtgctcagga agccatccaa agaggagcct ctgtttgctg
     8041 caagggtgat ctacgacctc ctcttcttct tcatggtcat catcatcgtc ctgaacctga
     8101 ttttcggggt catcattgac acctttgctg acctgaggag tgagaagcaa aagaaggagg
     8161 agatcttaaa aaccacgtgc ttcatctgcg gcttggaaag ggacaagttt gacaataaga
     8221 ctgtcacctt tgaagagcac atcaaggaag agcacaacat gtggcactat ctgtgcttca
     8281 tcgtgctggt gaaagtgaag gactccacag agtacaccgg gcctgagagt tacgtggcag
     8341 agatgatcag ggaaagaaac cttgattggt tccccagaat gagagccatg tccctggtca
     8401 gcagcgattc tgaaggggaa cagaacgagc tgaggaacct gcaggagaag ctggagtcta
     8461 ccatgaagct ggtcaccaat ctttctggcc agctgtcaga actaaaggac cagatgacag
     8521 aacagaggaa gcagaaacaa agaatcggcc ttctaggaca tcctcctcac atgaatgtca
     8581 acccacagca gccggcctag gcaaatgagg cagagggact ctgctcagcc ctctgtatat
     8641 cactgtcagg gtgggtacgg ctcattggtt ctgatttgcc cactaagggt acatgtgcgc
     8701 ttagtacatt tgtaaatact cagttttgta ttgtatgtat atgattgcta ttctcagagg
     8761 tttggacttt cgtattgtaa ttagctctgt tggcatggtg acttgtcact cctgccaaaa
     8821 atattaaaaa tgcctttttt ggaaggacta cagaaagtac ctgatttgca cttgaaccag
     8881 attatagatt taaaagtata tgacatgtat tttgtattta aaactagaat agccagtatt
     8941 tatgtttttt ataaaactgt gcaatacaaa ttatgcaatc accataactt tgtaactcct
     9001 gagtgtccta agggagtaca catctttgaa gctgatttgt tgatactcgt gtaataaatg
     9061 gttaaatatc aaatgctgct gctgctgcca aaattatatt aatagcgagt ttctggcccc
     9121 tgggcaattt tgtaccttgt aattatccta tggtgatgct gtttctcgtt gctaatggca
     9181 ttagtgcccc tgtatcctag tgataactcc aggtctgtga accattcaaa cagcattcat
     9241 tttgagaaaa gcaactttag tttcaaggat aattttaagc ttcaaaatta atcatttaaa
     9301 gtgtttcttt aagagagcca tgttagaggc tcacacttta gcttgaaagg agttgatgaa
     9361 ttaatttttt aaagggaact ttttacatga cgtttggaat aacagcatat tgctgaccag
     9421 tcagtgtcat ctcccgggtg aattttgatg tcacgttata gtcaaatgag ttagctgatg
     9481 gtttctagat tttcttcctc tgaaccatga tgcagtaggt aagaagttat tatgcgtata
     9541 tacatatata cattcatata cgacaaagta ggagctgtcc ccttaggatg catagctgcc
     9601 cctagggtac gtagctgaac actgacaatg gcgttcttct gaaagagcca cgtttgggtt
     9661 ttatttcttt gtcacatgat ttcttttctg gatgggtgca aagtatcaca ggaagtgttt
     9721 tctctctgtc gccttgtttt gtacctgggt ctcgctttac tagaccgtct ctgcacaaaa
     9781 gtttaaaaac tgaaccgtat gcagagttcc gaagcaagtc aagtttgtaa atgcatacct
     9841 aaaaatattt aataaacgat gcagaatcct atgcagt
//
