LOCUS       NM_001029872            3975 bp    mRNA    linear   ROD 21-MAY-2024
DEFINITION  Mus musculus integrin, alpha D (Itgad), mRNA.
ACCESSION   NM_001029872 XM_355945
VERSION     NM_001029872.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3975)
  AUTHORS   Hou,L. and Yuki,K.
  TITLE     CD11a regulates hematopoietic stem and progenitor cells
  JOURNAL   Front Immunol 14, 1219953 (2023)
   PUBMED   37781399
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3975)
  AUTHORS   Casteel,J.L., Keever,K.R., Ardell,C.L., Williams,D.L., Gao,D.,
            Podrez,E.A., Byzova,T.V. and Yakubenko,V.P.
  TITLE     Modification of Extracellular Matrix by the Product of DHA
            Oxidation Switches Macrophage Adhesion Patterns and Promotes
            Retention of Macrophages During Chronic Inflammation
  JOURNAL   Front Immunol 13, 867082 (2022)
   PUBMED   35720381
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3975)
  AUTHORS   Bailey,W.P., Cui,K., Ardell,C.L., Keever,K.R., Singh,S.,
            Rodriguez-Gil,D.J., Ozment,T.R., Williams,D.L. and Yakubenko,V.P.
  TITLE     Frontline Science: The expression of integrin alphaD beta2
            (CD11d/CD18) on neutrophils orchestrates the defense mechanism
            against endotoxemia and sepsis
  JOURNAL   J Leukoc Biol 109 (5), 877-890 (2021)
   PUBMED   33438263
  REMARK    GeneRIF: Frontline Science: The expression of integrin alphaD beta2
            (CD11d/CD18) on neutrophils orchestrates the defense mechanism
            against endotoxemia and sepsis.
REFERENCE   4  (bases 1 to 3975)
  AUTHORS   Hou,L., Voit,R.A., Sankaran,V.G., Springer,T.A. and Yuki,K.
  TITLE     CD11c regulates hematopoietic stem and progenitor cells under
            stress
  JOURNAL   Blood Adv 4 (24), 6086-6097 (2020)
   PUBMED   33351105
REFERENCE   5  (bases 1 to 3975)
  AUTHORS   Cui,K., Podolnikova,N.P., Bailey,W., Szmuc,E., Podrez,E.A.,
            Byzova,T.V. and Yakubenko,V.P.
  TITLE     Inhibition of integrin alphaDbeta2-mediated macrophage adhesion to
            end product of docosahexaenoic acid (DHA) oxidation prevents
            macrophage accumulation during inflammation
  JOURNAL   J Biol Chem 294 (39), 14370-14382 (2019)
   PUBMED   31395659
REFERENCE   6  (bases 1 to 3975)
  AUTHORS   Podolnikova,N.P., Kushchayeva,Y.S., Wu,Y., Faust,J. and
            Ugarova,T.P.
  TITLE     The Role of Integrins alphaMbeta2 (Mac-1, CD11b/CD18) and
            alphaDbeta2 (CD11d/CD18) in Macrophage Fusion
  JOURNAL   Am J Pathol 186 (8), 2105-2116 (2016)
   PUBMED   27315778
  REMARK    GeneRIF: The results indicate that both Mac-1 and alphaDbeta2
            support macrophage fusion with Mac-1 playing a dominant role
REFERENCE   7  (bases 1 to 3975)
  AUTHORS   Thomas,A.P., Dunn,T.N., Oort,P.J., Grino,M. and Adams,S.H.
  TITLE     Inflammatory phenotyping identifies CD11d as a gene markedly
            induced in white adipose tissue in obese rodents and women
  JOURNAL   J Nutr 141 (6), 1172-1180 (2011)
   PUBMED   21508205
  REMARK    GeneRIF: Relative white adipose tissue (WAT) expression of CD11d
            was massively induced by obesity to an extent greater than any
            other inflammatory marker (to >300-fold of controls in the 45 and
            60% fat groups) and this induction was WAT specific.
REFERENCE   8  (bases 1 to 3975)
  AUTHORS   Miyazaki,Y., Bunting,M., Stafforini,D.M., Harris,E.S.,
            McIntyre,T.M., Prescott,S.M., Frutuoso,V.S., Amendoeira,F.C., de
            Oliveira Nascimento,D., Vieira-de-Abreu,A., Weyrich,A.S.,
            Castro-Faria-Neto,H.C. and Zimmerman,G.A.
  TITLE     Integrin alphaDbeta2 is dynamically expressed by inflamed
            macrophages and alters the natural history of lethal systemic
            infections
  JOURNAL   J Immunol 180 (1), 590-600 (2008)
   PUBMED   18097061
  REMARK    GeneRIF: These studies identify previously unrecognized and unique
            activities of integrin alphaDbeta2, and macrophages that express
            it, in host defense and injury.
REFERENCE   9  (bases 1 to 3975)
  AUTHORS   Adams,J.E., Webb,M.S., Hu,X., Staunton,D. and Barnum,S.R.
  TITLE     Disruption of the beta2-integrin CD11d (alphaDbeta2) gene fails to
            protect against experimental autoimmune encephalomyelitis
  JOURNAL   J Neuroimmunol 184 (1-2), 180-187 (2007)
   PUBMED   17254640
REFERENCE   10 (bases 1 to 3975)
  AUTHORS   Wu,H., Rodgers,J.R., Perrard,X.Y., Perrard,J.L., Prince,J.E.,
            Abe,Y., Davis,B.K., Dietsch,G., Smith,C.W. and Ballantyne,C.M.
  TITLE     Deficiency of CD11b or CD11d results in reduced staphylococcal
            enterotoxin-induced T cell response and T cell phenotypic changes
  JOURNAL   J Immunol 173 (1), 297-306 (2004)
   PUBMED   15210787
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124566.5 and AW495405.1.
            
            On Apr 22, 2010 this sequence version replaced NM_001029872.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            CCDS Note: The coding region has been updated to represent a change
            to the splice pattern, in addition to an extension of the
            N-terminus of the encoded protein. The N-terminus is extended by 5
            aa, and the protein is updated from 1164 aa to 1202 aa.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK156218.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849388 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                AC124566.5         115081-115159       c
            80-185              AC124566.5         113367-113472       c
            186-289             AC124566.5         111165-111268       c
            290-360             AC124566.5         110956-111026       c
            361-475             AC124566.5         110708-110822       c
            476-606             AC124566.5         107285-107415       c
            607-752             AC124566.5         105987-106132       c
            753-860             AC124566.5         105658-105765       c
            861-1014            AC124566.5         103302-103455       c
            1015-1165           AC124566.5         103055-103205       c
            1166-1239           AC124566.5         102801-102874       c
            1240-1369           AC124566.5         99747-99876         c
            1370-1512           AC124566.5         99518-99660         c
            1513-1653           AC124566.5         99201-99341         c
            1654-1863           AC124566.5         98904-99113         c
            1864-1994           AC124566.5         98108-98238         c
            1995-2152           AC124566.5         97857-98014         c
            2153-2307           AC124566.5         96868-97022         c
            2308-2436           AC124566.5         96507-96635         c
            2437-2510           AC124566.5         95681-95754         c
            2511-2652           AC124566.5         95367-95508         c
            2653-2766           AC124566.5         90884-90997         c
            2767-2846           AC124566.5         90688-90767         c
            2847-2930           AC124566.5         90496-90579         c
            2931-3009           AC124566.5         86072-86150         c
            3010-3117           AC124566.5         85840-85947         c
            3118-3195           AC124566.5         85682-85759         c
            3196-3309           AC124566.5         85395-85508         c
            3310-3411           AC124566.5         85154-85255         c
            3412-3522           AC124566.5         84460-84570         c
            3523-3633           AC124566.5         83933-84043         c
            3634-3975           AW495405.1         5-346               c
FEATURES             Location/Qualifiers
     source          1..3975
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 70.0 cM"
     gene            1..3975
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /note="integrin, alpha D"
                     /db_xref="GeneID:381924"
                     /db_xref="MGI:MGI:3578624"
     exon            1..79
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..3636
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /codon_start=1
                     /product="integrin alpha-D precursor"
                     /protein_id="NP_001025043.3"
                     /db_xref="CCDS:CCDS21890.2"
                     /db_xref="GeneID:381924"
                     /db_xref="MGI:MGI:3578624"
                     /translation="MHCSAMVRGVVILLCGWALASCHGSNLDVEKPVVFKEDAASFGQ
                     TVVQFGGSRLVVGAPLEAVAVNQTGQLYDCAPATGVCQPILLHIPLEAVNMSLGLSLV
                     ADTNNSQLLACGPTAQRACAKNMYAKGSCLLLGSSLQFIQAIPATMPECPGQEMDIAF
                     LIDGSGSIDQSDFTQMKDFVKALMGQLASTSTSFSLMQYSNILKTHFTFTEFKSSLSP
                     QSLVDAIVQLQGLTYTASGIQKVVDSNRLLLLRVWSALKPGCHYNTHMPWWVWQRVRF
                     SWKELFHSKNGARKSAKKILIVITDGQKFRDPLEYRHVIPEAEKAGIIRYAIGVGDAF
                     REPTALQELNTIGSAPSQDHVFKVGNFVALRSIQRQIQEKIFAIEGTESRSSSSFQHE
                     MSQEGFSSALSMDGPVLGAVGSFSWSGGAFLYPSNMRSTFINMSQENEDMRDAYLGYS
                     TALAFWKGVHSLILGAPRHQHTGKVVIFTQESRHWRPKSEVRGTQIGSYFGASLCSVD
                     MDRDGSTDLVLIGVPHYYEHTRGGQVSVCPMPGVRSRWHCGTTLHGEQGHPWGRFGAA
                     LTVLGDVNGDSLADVAIGAPGEEENRGAVYIFHGASRQDIAPSPSQRVTGSQLFLRLQ
                     YFGQSLSGGQDLTQDGLVDLAVGAQGHVLLLRSLPLLKVGISIRFAPSEVAKTVYQCW
                     GRTPTVLEAGEATVCLTVRKGSPDLLGDVQSSVRYDLALDPGRLISRAIFDETKNCTL
                     TRRKTLGLGDHCETMKLLLPDCVEDAVTPIILRLNLSLAGDSAPSRNLRPVLAVGSQD
                     HVTASFPFEKNCKQELLCEGNLGVSFNFSGLQVLEVGSSPELTVTVTVWNEGEDSYGT
                     LIKFYYPAELSYRRVTRAQQPHPYPLRLACEAEPTGQESLRSSSCSINHPIFREGAKA
                     TFMITFDVSYKAFLGDRLLLRASASSENNKPETSKTAFQLELPVKYTVYTVISRQEDS
                     TKHFNFSSSHGERQKEAEHRYRVNNLSPLTLAISVNFWVPILLNGVAVWDVTLRSPAQ
                     GVSCVSQREPPQHSDLLTQIQGRSVLDCAIADCLHLRCDIPSLGTLDELDFILKGNLS
                     FGWISQTLQKKVLLLSEAEITFNTSVYSQLPGQEAFLRAQVSTMLEEYVVYEPVFLMV
                     FSSVGGLLLLALITVALYKLGFFKRQYKEMLDLPSADPDPAGQADSNHETPPHLTS"
     exon            80..185
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            186..289
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            290..360
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            361..475
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            476..606
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            607..752
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            753..860
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            861..1014
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1165
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1239
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            1240..1369
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1512
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..1653
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            1654..1863
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            1864..1994
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            1995..2152
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            2153..2307
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            2308..2436
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            2437..2510
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            2511..2652
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            2653..2766
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            2767..2846
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            2847..2930
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            2931..3009
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            3010..3117
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            3118..3195
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            3196..3309
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            3310..3411
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            3412..3522
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     exon            3523..3965
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3941..3946
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /note="hexamer: AATAAA"
     regulatory      3946..3951
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /note="hexamer: AATGAA"
     polyA_site      3961
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
     polyA_site      3965
                     /gene="Itgad"
                     /gene_synonym="Cd11d"
                     /note="major polyA site"
ORIGIN      
        1 gcaggctcta cagctctcta cttcctaatg cactgctcag ctatggtccg tggagttgtg
       61 atcctcctgt gtggctgggc cctggcttcc tgtcatgggt ctaacctgga tgtggagaag
      121 cccgtcgtgt tcaaagagga tgcagccagc ttcggacaga ctgtggtgca gtttggtgga
      181 tctcgactcg tggtgggagc ccctctggag gcggtggcag tcaaccaaac aggacagttg
      241 tatgactgtg cgcctgccac tggcgtgtgc cagcccatct tactgcacat tcccctagag
      301 gcagtgaaca tgtccctggg cctgtctctg gtggctgaca ccaataactc ccagttgctg
      361 gcttgtggtc caactgcaca gagagcttgt gcaaagaaca tgtatgcaaa aggttcctgc
      421 ctccttctgg gctccagctt gcagttcatc caggcaatcc ctgctaccat gccagagtgt
      481 ccaggacaag agatggacat tgctttcctg attgatggct ccggcagcat tgatcaaagt
      541 gactttaccc agatgaagga cttcgtcaaa gctttgatgg gccagttggc gagcaccagc
      601 acctcgttct ccctgatgca atactcaaac atcctgaaga ctcattttac cttcacggaa
      661 ttcaagagca gcctgagccc tcagagcctg gtggatgcca tcgtccagct ccaaggcctg
      721 acgtacacag cctcgggcat ccagaaagtg gtagacagca acaggctcct tcttctacgt
      781 gtctggtcag cactgaagcc aggttgccac tacaacactc acatgccatg gtgggtctgg
      841 cagagggtac ggttctcctg gaaagagcta tttcatagca agaatggggc ccgaaaaagt
      901 gccaagaaga tactaattgt catcacagat gggcagaaat tcagagaccc cctggagtat
      961 agacatgtca tccctgaagc agagaaagct gggatcattc gctatgctat aggggtggga
     1021 gatgccttcc gggaacccac tgccctacag gagctgaaca ccattggctc agctccctcg
     1081 caggaccacg tgttcaaggt gggcaatttt gtagcacttc gcagcatcca gcggcaaatt
     1141 caggagaaaa tctttgccat tgaaggaacc gaatcaaggt caagtagttc ctttcagcac
     1201 gagatgtcac aagaaggttt cagctcagct ctctcaatgg atggaccagt tctgggggct
     1261 gtgggaagct tcagctggtc tggaggtgcc ttcttgtacc cctcaaatat gagatccacc
     1321 ttcatcaaca tgtctcagga gaacgaggat atgagggacg cttacctggg ttactccacc
     1381 gcactggcct tttggaaggg ggtccacagc ctgatcctgg gggcccctcg ccaccagcac
     1441 acggggaagg ttgtcatctt tacccaggaa tccaggcact ggaggcccaa gtctgaagtc
     1501 agagggacac agatcggctc ctactttggg gcatctctct gttctgtgga catggataga
     1561 gatggcagca ctgacctggt cctgattgga gtcccccatt actatgagca cacccgaggg
     1621 gggcaggtgt cggtgtgccc catgcctggt gtgaggagca ggtggcattg tgggaccacc
     1681 ctccatgggg agcagggcca tccttggggc cgctttgggg cggctctgac agtgctaggg
     1741 gacgtgaatg gggacagtct ggcggatgtg gctattggtg cacccggaga ggaggagaac
     1801 agaggtgctg tctacatatt tcatggagcc tcgagacagg acatcgctcc ctcgcctagc
     1861 cagcgggtca ctggctccca gctcttcctg aggctccaat attttgggca gtcattaagt
     1921 gggggtcagg accttacaca ggatggcctg gtggacctgg ccgtgggagc ccaggggcac
     1981 gtgctgctgc ttaggagtct gcctttgctg aaagtgggga tctccattag atttgccccc
     2041 tcagaggtgg caaagactgt gtaccagtgc tggggaagga ctcccactgt cctcgaagct
     2101 ggagaggcca ccgtctgtct cactgtccgc aaaggttcac ctgacctgtt aggtgatgtc
     2161 caaagctctg tcaggtatga tctggcgttg gatccgggcc gtctgatttc tcgtgccatt
     2221 tttgatgaga cgaagaactg cactttgacc cgaaggaaga ctctggggct tggtgatcac
     2281 tgcgaaacaa tgaagctgct tttgccagac tgtgtggagg atgcagtgac ccctatcatc
     2341 ctgcgcctta acttatccct ggcaggggac tctgctccat ccaggaacct tcgtcctgtg
     2401 ctggctgtgg gctcacaaga ccatgtaaca gcttctttcc cgtttgagaa gaactgtaag
     2461 caggagctcc tgtgtgaggg gaacctgggc gtcagcttca acttctcagg cctgcaggtc
     2521 ttggaggtag gaagctcccc agagctcact gtgacagtaa cagtttggaa tgagggtgag
     2581 gacagctatg gaaccttaat caagttctac tacccagcag agctatctta ccgacgggtg
     2641 acaagagccc agcaacctca tccgtaccca ctacgcctgg catgtgaggc tgagcccacg
     2701 ggccaggaga gcctgaggag cagcagctgt agcatcaatc accccatctt ccgagaaggt
     2761 gccaaggcca ccttcatgat cacatttgat gtctcctaca aggccttcct gggagacagg
     2821 ttgcttctga gggccagcgc aagcagtgag aataataagc ctgaaaccag caagactgcc
     2881 ttccagctgg agcttccggt gaagtacacg gtctataccg tgatcagtag gcaggaagat
     2941 tctaccaagc atttcaactt ctcatcttcc cacggggaga gacagaaaga ggccgaacat
     3001 cgatatcgtg tgaataacct gagtccattg acgctggcca tcagcgttaa cttctgggtc
     3061 cccatccttc tgaatggtgt ggccgtgtgg gatgtgactc tgaggagccc agcacagggt
     3121 gtctcctgtg tgtcacagag ggaacctcct caacattccg accttctgac ccagatccaa
     3181 ggacgctctg tgctggactg cgccatcgcc gactgcctgc acctccgctg tgacatcccc
     3241 tccttgggca ccctggatga gcttgacttc attctgaagg gcaacctcag cttcggctgg
     3301 atcagtcaga cattgcagaa aaaggtgttg ctcctgagtg aggctgaaat cacattcaac
     3361 acatctgtgt attcccagct gccgggacag gaggcatttc tgagagccca ggtgtcaacg
     3421 atgctagaag aatacgtggt ctatgagccc gtcttcctca tggtgttcag ctcagtggga
     3481 ggtctgctgt tactggctct catcactgtg gcgctgtaca agcttggctt cttcaaacgt
     3541 cagtataaag agatgctgga tctaccatct gcagatcctg acccagccgg ccaggcagat
     3601 tccaaccatg agactcctcc acatctcacg tcctaggaat ctactttcct gtatatctcc
     3661 acaattacga gattggtttt gcttttgcct atgaatctac tggcatggga acaagttctc
     3721 ttcagctctg ggctagcctg ggaaacttcc cagaaatgat gccctacctc ctgagctggg
     3781 agatttttat ggtttgccca tgtgtcagat ttcagtgctg atccactttt tttgcaagag
     3841 caggaatggg gtcagcataa atttacatat ggataagaac taacacaaga ctgagtaata
     3901 tgctcaatat tcaatgtatt gcttgtataa atttttaaaa aataaaatga aaatgcaggt
     3961 ggaaaaaaaa aaaaa
//
