LOCUS       NM_013565               4877 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus integrin alpha 3 (Itga3), transcript variant 1, mRNA.
ACCESSION   NM_013565
VERSION     NM_013565.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4877)
  AUTHORS   Moye,A.L., Dost,A.F., Ietswaart,R., Sengupta,S., Ya,V., Aluya,C.,
            Fahey,C.G., Louie,S.M., Paschini,M. and Kim,C.F.
  TITLE     Early-stage lung cancer is driven by a transitional cell state
            dependent on a KRAS-ITGA3-SRC axis
  JOURNAL   EMBO J 43 (14), 2843-2861 (2024)
   PUBMED   38755258
  REMARK    GeneRIF: Early-stage lung cancer is driven by a transitional cell
            state dependent on a KRAS-ITGA3-SRC axis.
REFERENCE   2  (bases 1 to 4877)
  AUTHORS   Abou Nader,N., Charrier,L., Meisnsohn,M.C., Banville,L.,
            Deffrennes,B., St-Jean,G., Boerboom,D., Zamberlam,G.,
            Brind'Amour,J., Pepin,D. and Boyer,A.
  TITLE     Lats1 and Lats2 regulate YAP and TAZ activity to control the
            development of mouse Sertoli cells
  JOURNAL   FASEB J 38 (9), e23633 (2024)
   PUBMED   38690712
REFERENCE   3  (bases 1 to 4877)
  AUTHORS   Zhang,X., Li,H., Wang,H., Zhang,Q., Deng,X., Zhang,S., Wang,L.,
            Guo,C., Zhao,F., Yin,Y., Zhou,T., Zhong,J., Feng,H., Chen,W.,
            Zhang,J., Feng,H. and Hu,R.
  TITLE     Iron/ROS/Itga3 mediated accelerated depletion of hippocampal neural
            stem cell pool contributes to cognitive impairment after
            hemorrhagic stroke
  JOURNAL   Redox Biol 71, 103086 (2024)
   PUBMED   38367510
  REMARK    GeneRIF: Iron/ROS/Itga3 mediated accelerated depletion of
            hippocampal neural stem cell pool contributes to cognitive
            impairment after hemorrhagic stroke.
REFERENCE   4  (bases 1 to 4877)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   5  (bases 1 to 4877)
  AUTHORS   Bosquetti,B., Santana,A.A., Gregorio,P.C., Cunha,R.S.D.,
            Miniskiskosky,G., Budag,J., Franco,C.R.C., Ramos,E.A.S.,
            Barreto,F.C. and Stinghen,A.E.M.
  TITLE     The Role of alpha3beta1 Integrin Modulation on Fabry Disease
            Podocyte Injury and Kidney Impairment
  JOURNAL   Toxins (Basel) 15 (12), 700 (2023)
   PUBMED   38133204
  REMARK    GeneRIF: The Role of alpha3beta1 Integrin Modulation on Fabry
            Disease Podocyte Injury and Kidney Impairment.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4877)
  AUTHORS   Shakibaei,M., Zimmermann,B. and Merker,H.J.
  TITLE     Changes in integrin expression during chondrogenesis in vitro: an
            immunomorphological study
  JOURNAL   J Histochem Cytochem 43 (10), 1061-1069 (1995)
   PUBMED   7560884
REFERENCE   7  (bases 1 to 4877)
  AUTHORS   Stepp,M.A., Zhu,L., Sheppard,D. and Cranfill,R.L.
  TITLE     Localized distribution of alpha 9 integrin in the cornea and
            changes in expression during corneal epithelial cell
            differentiation
  JOURNAL   J Histochem Cytochem 43 (4), 353-362 (1995)
   PUBMED   7534781
REFERENCE   8  (bases 1 to 4877)
  AUTHORS   Takeuchi,K., Hirano,K., Tsuji,T., Osawa,T. and Irimura,T.
  TITLE     cDNA cloning of mouse VLA-3 alpha subunit
  JOURNAL   J Cell Biochem 57 (2), 371-377 (1995)
   PUBMED   7759572
REFERENCE   9  (bases 1 to 4877)
  AUTHORS   Morse,H.C. 3rd.
  TITLE     Genetic nomenclature for loci controlling surface antigens of mouse
            hemopoietic cells
  JOURNAL   J Immunol 149 (10), 3129-3134 (1992)
   PUBMED   1431091
  REMARK    Review article
            Erratum:[J Immunol 1993 Mar 15;150(6):2563]
REFERENCE   10 (bases 1 to 4877)
  AUTHORS   Tamura,R.N., Cooper,H.M., Collo,G. and Quaranta,V.
  TITLE     Cell type-specific integrin variants with alternative alpha chain
            cytoplasmic domains
  JOURNAL   Proc Natl Acad Sci U S A 88 (22), 10183-10187 (1991)
   PUBMED   1946438
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC053031.1 and BQ032311.1.
            
            On Apr 16, 2015 this sequence version replaced NM_013565.2.
            
            Summary: This gene encodes a subunit of integrin family of cell
            surface proteins. The encoded protein undergoes post-translational
            processing to form a disulfide bond-linked dimer comprised of heavy
            and light chains. At the cell surface, the encoded protein
            non-covalently associates with the integrin beta-1 subunit to form
            a heterodimer that interacts with many extracellular matrix
            proteins including fibronectin and laminin. Mice lacking the
            encoded protein die during the first day after birth due to severe
            abnormalities in kidneys. Mice lacking the encoded protein
            specifically in the basal layer of epidermis display several skin
            defects and accelerated wound healing. Alternative splicing results
            in multiple transcript variants encoding different isoforms.
            [provided by RefSeq, Apr 2015].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC053031.1, SRR13948564.3939540.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4853              BC053031.1         1-4853
            4854-4877           BQ032311.1         1-24                c
FEATURES             Location/Qualifiers
     source          1..4877
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 59.01 cM"
     gene            1..4877
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /note="integrin alpha 3"
                     /db_xref="GeneID:16400"
                     /db_xref="MGI:MGI:96602"
     exon            1..584
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     CDS             379..3540
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /note="isoform 1 preproprotein is encoded by transcript
                     variant 1; galactoprotein B3; CD49 antigen-like family
                     member C; VLA-3 receptor, alpha 3 subunit"
                     /codon_start=1
                     /product="integrin alpha-3 isoform 1 preproprotein"
                     /protein_id="NP_038593.1"
                     /db_xref="CCDS:CCDS25271.1"
                     /db_xref="GeneID:16400"
                     /db_xref="MGI:MGI:96602"
                     /translation="MGPGPCRVPRAPGWLLRALALMVAACGRVAFAFNLDTRFLVVKE
                     AVNPGSLFGYSVALHRQTERQQRYLLLAGAPRDLAVGDDYTNRTGAVYLCPLTAHKDD
                     CERMDISEKSDPDHHIIEDMWLGVTVASQGPAGRVLVCAHRYTKVLWSGLEDQRRMVG
                     KCYVRGNDLQLDPGDDWQTYHNEMCNSNTDYLQTGMCQLGTSGGFTQNTVYFGAPGAY
                     NWKGNSYMIQRKDWDLSEYSYRGSEEQGNLYIGYTVQVGNAILHPTDIITVVTGAPRH
                     QHMGAVFLLKQESGGDLQRKQVLKGTQVGAYFGSAIALADLNNDGWQDLLVGAPYYFE
                     RKEEVGGAVYVFMNQAGASFPDQPSLLLHGPSRSAFGISIASIGDINQDGFQDIAVGA
                     PFEGLGKVYIYHSSSGGLLRQPQQIIHGEKLGLPGLATFGYSLSGKMDVDENLYPDLL
                     VGSLSDHIVLLRARPVINILHRTLVARPAVLDPALCTATSCVQVELCFAYNQSAGNPN
                     YRRNITLAYTLEADRDRRPPRLRFARSQSSVFHGFFSMPETHCQTLELLLMDNVRDKL
                     RPIVIAMNYSLPLRMPDRLKLGLRSLDAYPVLNQAQAMENHTEVHFQKECGPDNKCDS
                     NLQMRAAFLSEQLQPLSRLQYSRDTKKLFLSINVTNSPSSQRAGEDAHEALLTLEVPS
                     ALLLSSVRPSGTCQANNETILCELGNPFKRNQRMELLIAFEVIGVTLHTRDLPVLLQL
                     STSSHQDNLQPVLLTLQVDYTLQASLSLMNHRLQSFFGGTVMGEAAMKTAEDVGSPLK
                     YEFQVSPVGDGLAALGTLVLGLEWPYEVTNGKWLLYPTEITIHSNGSWPCQPSGNLVN
                     PLNLTLSDPGVTPLSPQRRRRQLDPGGDQSSPPVTLAAAKKAKSETVLTCSNGRARCV
                     WLECPLPDTSNITNVTVKARVWNSTFIEDYKDFDRVRVDGWATLFLRTSIPTINMENK
                     TTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALY
                     EAKRQKAEMKSQPSETERLTDDY"
     exon            585..712
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            713..792
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            793..1042
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1129
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1340
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1341..1537
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1538..1626
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1627..1763
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1764..1850
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1851..1918
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            1919..2055
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2056..2205
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2206..2303
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2304..2451
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2452..2523
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2524..2603
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2604..2681
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2682..2784
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2785..2967
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            2968..3090
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            3091..3204
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            3205..3303
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            3304..3429
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            3430..3571
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     exon            3572..4860
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4839..4844
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /note="hexamer: AATAAA"
     polyA_site      4860
                     /gene="Itga3"
                     /gene_synonym="CD49C; GAPB3"
                     /note="major polyA site"
ORIGIN      
        1 cctccctcct gccctcctgg tgatcgaggg cttgccgttc taaatcctcc acctagccga
       61 ggtccaaaga gctaacacct ccaagggggc gcggccggga ccatctaggg tgtggggtgc
      121 tcggagctcg gaacggtgac ccgtccaccg aaccaacgtg agagtagatc cacggatctg
      181 gaaaacggat tggaaaagca cccggagcag acgtgaaagt gacccggact agggtaaaaa
      241 attgcctgac taccggtgca gcggctctgc gggctcgggt gtcctctggt ggcgcctgga
      301 gcaggtgaac cgttcatcac tcccggtgct gagccctcta gcgatttcgc ccggcccctt
      361 acggcccggc ccgcagccat gggccccggc ccctgccgcg tgccccgcgc ccctggctgg
      421 ctgctccgcg ctctggcctt gatggtggcg gcttgcggcc gggtcgcctt cgccttcaac
      481 ctggacaccc gattcctggt ggtgaaggag gcggtgaacc ccggtagcct cttcggctac
      541 tcggtcgccc tccatcggca gactgagcga caacagcgct acctccttct ggccggggct
      601 ccccgggacc tcgctgtggg tgatgactat accaaccgga ctggtgctgt gtacctgtgt
      661 cccctcacgg cccacaagga cgactgtgaa cggatggaca tttcagagaa aagtgaccct
      721 gaccatcaca ttattgagga tatgtggctt ggagtgactg tggccagcca gggccctgca
      781 ggtagagtcc tggtctgtgc ccatcggtac accaaggtgc tgtggtctgg gctagaagac
      841 cagcggcgca tggtgggcaa gtgctatgtg cgtggcaatg acctacagct cgaccccggc
      901 gatgactggc agacatacca caacgagatg tgtaacagca acactgacta cttgcagacc
      961 ggcatgtgcc agctgggcac cagcggcggc ttcacccaga acaccgtata cttcggtgcc
     1021 cctggtgcct acaactggaa aggaaacagc tacatgattc agcggaagga ctgggattta
     1081 tctgaatata gctacagggg ctcagaggag caaggaaacc tttatattgg gtacacggtg
     1141 caggtaggca acgccatcct acatcccacg gacatcatca ctgttgtgac gggtgcccca
     1201 cggcaccaac atatgggcgc tgtcttcttg ctgaagcaag agtcaggtgg agacctgcag
     1261 aggaagcagg tgctgaaggg cacgcaggtg ggcgcttatt ttggcagtgc cattgccctg
     1321 gcagacctga acaatgatgg gtggcaggac ctcctggtgg gtgctcccta ctacttcgaa
     1381 cggaaagagg aggtaggggg tgccgtctat gtcttcatga accaggcggg cgcatccttc
     1441 cctgatcaac cttccctcct gcttcacggc cccagccgct ctgcctttgg catctctata
     1501 gccagcatcg gtgacatcaa ccaggatgga ttccaggaca tcgctgtggg agccccattt
     1561 gagggcttgg gcaaagtcta catctaccac agcagctccg gggggctcct caggcagccc
     1621 cagcagataa tccatggaga gaaactcgga ctgccaggct tggccacctt cggctactcc
     1681 ctgagcggga agatggatgt ggatgaaaac ctttacccag acctgctagt agggagcctg
     1741 tcggaccaca tcgtgctgct gcgggcccgg cctgtcatca atatcctcca taggaccttg
     1801 gtggccaggc cagctgtgtt ggaccctgcg ctttgtacag ctacctcctg tgttcaggtg
     1861 gagctgtgtt ttgcctacaa ccagagcgct gggaacccca actacaggcg gaacatcacc
     1921 ctggcttaca cactggaggc tgacagggac cgacgcccac ccaggctccg atttgcccgc
     1981 agccagtcat ctgtcttcca cggcttcttc tccatgccag agacacattg ccagacactg
     2041 gagttactgc tgatggacaa tgttcgcgat aaactccgtc ctatcgtcat tgccatgaac
     2101 tactccttac ctctgcgcat gcctgatcgc ctcaagctcg gcttgcggtc tctggatgcc
     2161 tacccagtcc tcaaccaggc acaggctatg gagaatcaca ctgaggtcca cttccagaaa
     2221 gagtgcgggc cagacaacaa gtgcgacagc aacctgcaga tgcgagcagc cttcctgtct
     2281 gagcagctgc agcctctaag caggctccag tacagcagag acactaagaa actgtttttg
     2341 agcatcaatg tgaccaattc accgagcagc caacgggctg gggaagatgc gcatgaggca
     2401 ttgctcaccc tagaggtgcc atccgccctg ctactgtcct ccgtgcgccc gtctgggacc
     2461 tgccaagcta ataacgagac catcctgtgt gagctaggaa accccttcaa acggaaccag
     2521 aggatggagc tgctcattgc ctttgaggtc atcggggtaa cgttgcacac gagggacctc
     2581 ccagtacttc ttcagctgtc cacgtcgagt caccaggaca acttgcagcc cgtactcctg
     2641 actttgcagg tggactacac cctccaggcc tcgctcagct taatgaatca tcggttgcag
     2701 agcttctttg gtggcacagt gatgggtgag gctgccatga aaactgcgga ggatgtggga
     2761 agtcccctga aatatgaatt ccaggtgagc ccagtgggag atgggctggc agccttgggc
     2821 acactggttc taggtctgga gtggccctat gaagttacca atggcaagtg gctgctgtac
     2881 cccacggaga tcaccatcca tagcaatggt tcctggccct gccagccgtc tggaaacctt
     2941 gtcaaccctc tcaaccttac tctctctgac cctggagtca caccactgtc gccacagcgc
     3001 cgccggcggc aactggatcc agggggagac cagagttccc cgcctgtcac actagctgct
     3061 gccaaaaaag ccaagtctga gactgtgttg acctgctcca atggccgtgc ccgctgtgtg
     3121 tggctggagt gcccccttcc agacacctcc aacattacca atgtgaccgt gaaagcacgg
     3181 gtgtggaaca gcaccttcat tgaggactac aaagactttg acagagtcag ggtagatggc
     3241 tgggctaccc tgttcctgag aaccagcatc cctaccatca acatggagaa caagaccaca
     3301 tggttctctg tggacattga ctcagagctg gtggaggagc tgccggctga gattgagctg
     3361 tggttggtgc ttgtggccgt gggtgctggg ttgctgctgc tggggctcat catcctcctc
     3421 ttgtggaagt gcggcttctt caagcgagcc cgcactcgtg ccctgtatga agctaagagg
     3481 cagaaggctg agatgaagag ccagccgtca gagacagaaa ggctgaccga cgactactga
     3541 ggggtcagcc cccctgcccc ggcccacccg gtgtgacttc tttaagccga cccgctacta
     3601 ccggattatg cccaagtacc atgcagtgcg tatccgggag gaggaccgct acccacctcc
     3661 agggagcacg ctacccacca agaagcactg ggtcaccagc tggcagattc gggaccgata
     3721 ctactgatgc cctccccgac aaaccttccg gcgctccctt ccttcctatt tatcataaat
     3781 tatgactccg acagtccaaa gggggccacg cccttggctg gcaccagcag gctcaggcat
     3841 ctatccctct tcagtgcagg catgttttct ggggccctgg aatctccttc aagaccttgc
     3901 aatgctgagc ccagcacagc ccttgcacag tggacacaca cacagggcct actgctaatg
     3961 gcctgctctg atatatcatg gagggtgccg tatccaagtc tctgtctgtg ccaaaaccaa
     4021 gccaaagcgc ctctactggg agacaggagg aaaaggtccc tgatgtgggg acacggctcc
     4081 tccacactga atcccccttg agccattgtc aatggatgga gtttactgtc cagaataaaa
     4141 ctactgatgc ggaggagaca gtcaggctca gctgcaattc ctgccaggca ctggagcgca
     4201 gggctacact aaaggctacc caggggatgt tcttacgacc tgcgtgctca gacgcaagag
     4261 caatgaacta gaaagcaggt cgccggaatg ggctttatgg gtgcatctct aaaatcgtgg
     4321 ctacagagag agctggcaag aaacgcagcc cgaaggaaca aagagagacc gtgggcagcc
     4381 tggacgcaca cactgtgctg ggactgacct ggagcatggc ggcatccttc agagagcagg
     4441 gtcctggcgc agcagacatt ggtaggatga agaggagaga cttctgatcc atcctgacca
     4501 cctcagcctg ggcaaggcct ggagatcccc acgagaccac gtggggtgtg atacttgaat
     4561 gtagcatggc aggggagggc ccagcccctg ccccagttgg ccagacttaa ctctgctccc
     4621 ttgaccacag agatgagatt ctgagctgcc tgtggctttc ttcccctccc ccaggggctg
     4681 catccccatt ctagcagtgg aggctgattt cccaggtcct ctccccatcc cggtccacag
     4741 gcaggcccac tccccagctc tgtcccctcc accccacggt actataacaa cttccccgat
     4801 cctgtgcctt ctttgtatat gggcttctca ctaaaataaa taaactgttc ccagtttgta
     4861 aaaaaaaaaa aaaaaaa
//
