LOCUS       NM_001033228            5984 bp    mRNA    linear   ROD 31-DEC-2024
DEFINITION  Mus musculus integrin alpha 1 (Itga1), mRNA.
ACCESSION   NM_001033228 XM_907952 XM_920666 XM_920670 XM_920675
VERSION     NM_001033228.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5984)
  AUTHORS   Ray,A.T. and Soriano,P.
  TITLE     FGF signaling regulates salivary gland branching morphogenesis by
            modulating cell adhesion
  JOURNAL   Development 150 (6) (2023)
   PUBMED   36861436
REFERENCE   2  (bases 1 to 5984)
  AUTHORS   Song,W., Li,Q., Wang,T., Li,Y., Fan,T., Zhang,J., Wang,Q., Pan,J.,
            Dong,Q., Sun,Z.S. and Wang,Y.
  TITLE     Putative complement control protein CSMD3 dysfunction impairs
            synaptogenesis and induces neurodevelopmental disorders
  JOURNAL   Brain Behav Immun 102, 237-250 (2022)
   PUBMED   35245678
REFERENCE   3  (bases 1 to 5984)
  AUTHORS   Eckert,I.N., Ribechini,E., Jarick,K.J., Strozniak,S., Potter,S.J.,
            Beilhack,A. and Lutz,M.B.
  TITLE     VLA-1 Binding to Collagen IV Controls Effector T Cell Suppression
            by Myeloid-Derived Suppressor Cells in the Splenic Red Pulp
  JOURNAL   Front Immunol 11, 616531 (2021)
   PUBMED   33584706
  REMARK    GeneRIF: VLA-1 Binding to Collagen IV Controls Effector T Cell
            Suppression by Myeloid-Derived Suppressor Cells in the Splenic Red
            Pulp.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5984)
  AUTHORS   Bromley,S.K., Akbaba,H., Mani,V., Mora-Buch,R., Chasse,A.Y.,
            Sama,A. and Luster,A.D.
  TITLE     CD49a Regulates Cutaneous Resident Memory CD8+ T Cell Persistence
            and Response
  JOURNAL   Cell Rep 32 (9), 108085 (2020)
   PUBMED   32877667
REFERENCE   5  (bases 1 to 5984)
  AUTHORS   Brignani,S., Raj,D.D.A., Schmidt,E.R.E., Dudukcu,O., Adolfs,Y., De
            Ruiter,A.A., Rybiczka-Tesulov,M., Verhagen,M.G., van der Meer,C.,
            Broekhoven,M.H., Moreno-Bravo,J.A., Grossouw,L.M., Dumontier,E.,
            Cloutier,J.F., Chedotal,A. and Pasterkamp,R.J.
  TITLE     Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic
            Neuron Migration and Dopaminergic Substantia Nigra Development
  JOURNAL   Neuron 107 (4), 684-702 (2020)
   PUBMED   32562661
REFERENCE   6  (bases 1 to 5984)
  AUTHORS   Shakibaei,M., Zimmermann,B. and Merker,H.J.
  TITLE     Changes in integrin expression during chondrogenesis in vitro: an
            immunomorphological study
  JOURNAL   J Histochem Cytochem 43 (10), 1061-1069 (1995)
   PUBMED   7560884
REFERENCE   7  (bases 1 to 5984)
  AUTHORS   Tarone,G., Russo,M.A., Hirsch,E., Odorisio,T., Altruda,F.,
            Silengo,L. and Siracusa,G.
  TITLE     Expression of beta 1 integrin complexes on the surface of
            unfertilized mouse oocyte
  JOURNAL   Development 117 (4), 1369-1375 (1993)
   PUBMED   7691492
REFERENCE   8  (bases 1 to 5984)
  AUTHORS   Morse,H.C. 3rd.
  TITLE     Genetic nomenclature for loci controlling surface antigens of mouse
            hemopoietic cells
  JOURNAL   J Immunol 149 (10), 3129-3134 (1992)
   PUBMED   1431091
  REMARK    Review article
            Erratum:[J Immunol 1993 Mar 15;150(6):2563]
REFERENCE   9  (bases 1 to 5984)
  AUTHORS   Douville,P., Seldin,M.F. and Carbonetto,S.
  TITLE     Genetic mapping of the integrin alpha 1 gene (Vla1) to mouse
            chromosome 13
  JOURNAL   Genomics 14 (2), 503-505 (1992)
   PUBMED   1427867
REFERENCE   10 (bases 1 to 5984)
  AUTHORS   Eicher,E.M. and Lee,B.K.
  TITLE     The NXSM recombinant inbred strains of mice: genetic profile for 58
            loci including the Mtv proviral loci
  JOURNAL   Genetics 125 (2), 431-446 (1990)
   PUBMED   2165966
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK035870.1, AK040830.1, AK053377.1 and AK033533.1.
            
            On Jul 25, 2007 this sequence version replaced NM_001033228.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK035870.1, SRR10223969.13192.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2776              AK035870.1         2-2777
            2777-3882           AK040830.1         1201-2306
            3883-3984           AK035870.1         3884-3985
            3985-5282           AK053377.1         384-1681
            5283-5984           AK033533.1         90-791
FEATURES             Location/Qualifiers
     source          1..5984
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 64.61 cM"
     gene            1..5984
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /note="integrin alpha 1"
                     /db_xref="GeneID:109700"
                     /db_xref="MGI:MGI:96599"
     exon            1..494
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     CDS             434..3973
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /note="VLA-1; laminin and collagen receptor; CD49
                     antigen-like family member A"
                     /codon_start=1
                     /product="integrin alpha-1 precursor"
                     /protein_id="NP_001028400.2"
                     /db_xref="CCDS:CCDS36788.1"
                     /db_xref="GeneID:109700"
                     /db_xref="MGI:MGI:96599"
                     /translation="MVPRRPASLEVTVACIWLLTVILGVCISFNVDVKNSMSFSGPVE
                     DMFGYTVQQYENEEGKWVLIGSPLVGQPKARTGDVYKCPVGRERSMPCVKLDLPVNTS
                     IPNVTEIKENMTFGSTLVTNPKGGFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNS
                     FAPVQECSTQLDIVIVLDGSNSIYPWESVTAFLNDLLKRMDIGPKQTQVGIVQYGANV
                     THEFNLNKYSSTEEVLVAANKIGRRGGLQTMTALGIDTARKEAFTEARGARRGVKKVM
                     VIVTDGESHDNYRLKQVIQDCEDENIQRFSIAILGHYNRGNLSTEKFVEEIKSIASEP
                     TEKHFFNVSDELALVTIVKALGERIFALEATADQSAASFEMEMSQTGFSAHYSQDWVM
                     LGAVGAYDWNGTVVMQKANQIVIPHNTTFQTEPTKMNEPLASYLGYTVNSATIPGDVL
                     YIAGQPRYNHTGQVVIYKMEDGDVNILQTLSGEQIGSYFGSVLTTIDIDKDSYTDLLL
                     VGAPMYMGTEKEEQGKVYVYAVNQTRFEYQMSLEPIKQTCCSSLKDNSCTKENKNEPC
                     GARFGTAVAAVKDLNVDGFNDVVIGAPLEDDHAGAVYIYHGSGKTIRKEYAQRIPSGG
                     DGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWARDVAVVKVTMNFEPNKVNI
                     QKKNCRVEGKETVCINATMCFHVKLKSKEDSVYEADLQYRVTLDSLRQISRSFFSGTQ
                     ERRIQRNLTVRESECIRHSFYMLDKHDFQDSVRVTLDFNLTDPENGPVLDDALPNSVH
                     GHIPFAKDCGNKERCVSDLTLDVSTTEKNLLIVRSQNDKFNVSLTVKNKGDSAYNTRT
                     VVQYSPNLIFSGIEEIQKDSCESNQNITCRVGYPFLRTGDVVNFKIIFQFNTSHLSEN
                     AIIHLSATSDSEEPLESLYDNEVNISIPVKYEVGLQFYSSASEHHISVAANETVPELI
                     NSTKDIGDEINVFYTIRKRGHFPMPELRLAISFPNLTSDGYPVLYPTGWSSSDNVNCR
                     PRSLEDPLGINSGKKMTISKSEVLKRGTIQDCSTCKIATITCHLLPSDVSQVNVSLIL
                     WKPTFIKAHFSSLNLTIRGELQSENSSLTLSSSNRKRELAIQISKDGLPGRVPLWVIL
                     LSAFAGLLLLMLLILALWKIGFFKRPLKKKMEK"
     exon            495..615
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            616..728
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            729..817
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            818..929
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1057
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1206
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1357
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            1358..1523
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            1524..1597
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            1598..1742
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            1743..1885
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            1886..2029
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            2030..2287
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            2288..2418
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            2419..2585
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            2586..2722
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            2723..2833
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            2834..3043
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            3044..3124
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            3125..3201
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            3202..3291
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            3292..3394
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            3395..3508
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            3509..3613
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            3614..3718
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            3719..3811
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            3812..3928
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     exon            3929..5984
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4358..4363
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /note="hexamer: AATAAA"
     polyA_site      4382
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /note="major polyA site"
     regulatory      4884..4889
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /note="hexamer: AATAAA"
     polyA_site      4904
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
     regulatory      5289..5294
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
                     /note="hexamer: AATGAA"
     polyA_site      5307
                     /gene="Itga1"
                     /gene_synonym="CD49A; E130012M19Rik; Vla1"
ORIGIN      
        1 gggatttggt tcgtgaagca agatcgccct ctcagtgaaa ggcagatgtc cctttaaggt
       61 ttgctttgct gctgcctgtg gactttagcc taaacacggt cccgcgaagt tggctttatt
      121 tgtccatgtc tcggacagag cctgggtggc tgccagtgag atttcagaga cttgagcgca
      181 aaggggcggg agatgtggca atccatctgg gatctgagaa gcgtggagcg ggcttagcag
      241 cattcgacca aaacacagga aattactctt ccaccgctcc agggcgctgc agccgctggg
      301 gccgctgccg gacacccgcg gagaccgcac cgagtgaccc agagcgcaag tcgccggcgc
      361 ctggcttctg cctgttcctg ccagctcctg cccacgaacc agtacgtcgc tggttccagc
      421 agccactcca gcaatggtcc ccaggcgtcc tgctagccta gaggtcactg tagcctgcat
      481 ctggcttctc accgttatcc taggcgtctg catctccttc aacgttgatg tcaaaaactc
      541 catgagcttc agtggtccag tggaggacat gtttggatac accgttcaac agtatgaaaa
      601 cgaagaaggc aaatgggttc ttattggttc tcctttagtt ggccaaccca aagcaagaac
      661 tggagatgtc tataagtgtc cagttgggag agagagatca atgccttgtg tgaagttgga
      721 tttaccagtt aacacatcga ttcctaatgt cacagaaata aaggaaaaca tgacatttgg
      781 atcaacttta gtcaccaatc cgaagggagg atttctggca tgtgggccct tgtatgccta
      841 tagatgtgga catttgcatt atacgactgg catatgttct gatgtcagcc ctacatttca
      901 agttgtgaac tcgttcgccc ctgtacaaga atgtagcaca cagcttgaca tagtcatcgt
      961 cctagatggc tccaacagca tctacccctg ggaaagtgtc actgcctttt taaacgacct
     1021 tcttaagagg atggacattg gccccaaaca gacacaggtt ggaattgtac aatatggagc
     1081 aaatgtaaca catgagttca acctcaataa gtattcatcc acagaagagg tcctggtggc
     1141 agcaaacaaa ataggccgca ggggtggtct ccagacgatg acagcccttg gaatagacac
     1201 agccaggaaa gaggcattca ctgaagctcg gggggccaga aggggagtga aaaaagtcat
     1261 ggttattgtg actgatggag aatcgcatga caactatcgc ctgaaacagg tcatccaaga
     1321 ctgtgaggat gaaaacattc agcgattttc catagctatc cttggccact ataacagggg
     1381 gaacttaagc accgaaaaat ttgtggagga gataaaatca atcgcaagtg agcccaccga
     1441 aaagcacttc ttcaacgtct cagatgagtt ggccctggtc actattgtta aagctctggg
     1501 agaaaggata tttgctttgg aagctacagc tgaccagtca gcagcttcgt ttgaaatgga
     1561 gatgtctcag accggcttca gtgctcatta ttcacaggac tgggtcatgc ttggagctgt
     1621 tggagcctat gactggaacg gaactgtggt catgcagaag gctaaccaga ttgtcatccc
     1681 tcataacacc acctttcaaa ctgagcccac caagatgaac gagcctcttg cttcttactt
     1741 gggttacaca gtgaactctg ccaccatccc gggagatgtg ctctatatcg ctgggcagcc
     1801 tcggtacaat cacaccggcc aggtcgtcat ctacaagatg gaggatgggg acgtcaacat
     1861 tctgcagaca ctcagtggag agcagatcgg atcctacttt ggtagcgtct taaccacaat
     1921 tgacatcgac aaagattctt acactgatct gcttctcgtc ggggctccca tgtatatggg
     1981 gacagagaaa gaggaacagg gcaaggtgta cgtgtacgct gtgaatcaga cgaggtttga
     2041 atatcaaatg agcctggaac caattaagca gacctgctgt tcatccctga aggataattc
     2101 atgcacaaaa gaaaacaaga atgagccctg tggggcccgt tttggaacag cagttgctgc
     2161 tgtaaaagac ctcaacgtgg atggctttaa tgacgtcgtg attggagctc ccctggaaga
     2221 cgaccacgca ggagctgtgt acatttatca tggcagtggc aagaccataa ggaaagagta
     2281 tgcgcaacgc attccctcag gtggggatgg gaagacgctg aaattttttg gccagtctat
     2341 ccacggagag atggatttaa atggcgatgg tctgactgac gtgaccattg gaggccttgg
     2401 aggagctgcc ctcttctggg ccagagatgt ggctgtagtt aaagtgacca tgaattttga
     2461 acccaacaaa gtgaatattc aaaagaaaaa ctgccgtgtg gagggcaaag aaacagtatg
     2521 cataaatgct acaatgtgtt ttcatgtgaa attgaagtct aaagaagact cagtttacga
     2581 ggctgatctg cagtaccgtg tcacccttga ttcgctgagg cagatatcac ggagcttttt
     2641 ttctggaact caggaaagga ggattcaaag aaacctcacc gttcgagaat ccgaatgcat
     2701 caggcactcc ttctacatgt tggataagca cgactttcag gactccgtga gagtgacttt
     2761 ggattttaac ctcactgatc cagaaaatgg gcccgtgctc gatgacgctc tgccaaactc
     2821 agtccatgga catattcctt ttgccaaaga ctgtgggaac aaggaaagat gcgtttcaga
     2881 cctcaccctg gatgtgtcca caacagaaaa gaacctgctg attgtcagat cccagaatga
     2941 caagttcaat gtcagcctca ccgtcaaaaa caagggagac agtgcgtaca acacccggac
     3001 agtggttcag tattctccaa atctgatttt ttcaggaatt gaggagatcc aaaaagatag
     3061 ctgcgaatcc aatcaaaata tcacgtgtag agttggatat cctttcctga ggacaggaga
     3121 cgtggttaac ttcaaaataa tattccagtt taatacatca catctctcag aaaatgcaat
     3181 tattcattta agtgcaacaa gtgacagtga agagcccctg gaatctcttt acgataatga
     3241 agtaaatatt tccatccccg taaaatatga agtcggactg cagttttaca gttctgcgag
     3301 tgaacaccac atttcagttg ctgccaatga gactgttcct gagctgatta attccaccaa
     3361 ggacattggg gatgaaatta atgtcttcta cacgattaga aaaagagggc atttcccaat
     3421 gccagaactt cggctggcaa tttcatttcc caatctgacg tcagatggct atcctgtact
     3481 gtacccaact ggatggtcat cttctgataa tgtaaactgc agacctcgaa gccttgagga
     3541 ccctttgggt atcaactctg ggaagaaaat gacaatatca aagtctgagg ttctcaaaag
     3601 aggcacaatc caggactgca gtacctgcaa gattgctacc atcacgtgtc atctccttcc
     3661 ctcggatgtg agtcaagtga atgtctcact catcttgtgg aaaccaactt tcataaaagc
     3721 acatttttcc agcttaaatc ttaccatacg gggagaactt cagagtgaaa actcatcgct
     3781 gactttaagc agcagcaacc ggaaacgaga gctggctatt cagatatcca aagacgggct
     3841 cccaggccga gtgccgctgt gggttatcct cctgagcgcc tttgcgggac tcctgctgtt
     3901 aatgctgctt atattagctc tgtggaagat tggattcttc aaaaggccac taaagaagaa
     3961 aatggagaaa tgaaatattt aaggaaaaaa accaataaca actattcaac aatctatcct
     4021 caggtttgcc tcaatcatgt gagaagaaat tcagaaatat agccaaagat gtggtcacat
     4081 agctccatgt actccatcat ccatctagga ttgcttactt ggaaagagac agatcaagtg
     4141 tgacccagaa aggctaccca aagatacagt gtagaaagca atgggaaata tttttaataa
     4201 ttactcattt ttgctgagta agtgaaatga caaagagttt taaagaagaa tcgtccgtat
     4261 aagtaccttt atgtgtttac gtgccacaca gagtatctta agggatgcac aaaaagagct
     4321 tcgtgttccg tgaagcagtt actctcagca cagcataaat aaagaatctc tccttggtca
     4381 catcttccga gtgacactca gcatttgtaa atgacaacac gggaatgggg tgaaaggttc
     4441 tcccagttca aatgagaaaa actttcctta gccaagctca tatacaatat ggactgaaaa
     4501 tagaattaga tcacgggtga cactcggtga ccttgtggat cccataaggt ggaaagagta
     4561 ttttccagtg tgattggaaa atagtgcagt tgagcttaaa ttctatgtag aataggcagt
     4621 caagatggag tccttattta aacatgagcg cactgaatct attaatttaa acttttacag
     4681 aaagtaaaac tgcttaattt atattgagct ctagaacaaa aaactcttat aatatatata
     4741 atatgtatgt atacgtatat atatattata tataaagttg aagcagcctg tgtagcataa
     4801 caatgataag tagtgaaaag ccacaccatg tgtgtgatgc ccagagggtt tcttaatgaa
     4861 acatgagcat acatagatga cccaataaaa ctgatgtcac ctttcctgag tagttattta
     4921 atgctagggc ttctgggatg tttcattaag tagggggctt ctcaactctg gtataaggat
     4981 catgtaaaac cacaaaatat gactgtttat tttaattttt ttcaattttc taaacacatt
     5041 ttatgttgtt attgaaaaaa gcagtctccc cggctaatgt tatattgtac caagaaatca
     5101 ctgctttcga acatggtgta tcagtattta aatagaaaac caggtaattt aaagaattta
     5161 tatcttgaaa acatatacta acagagacat acaactcatt tgtttgcact tctgttttcc
     5221 tgaaataatc cctgaggccc gtggactctg ctgtaacata agcttgcaga ttgctccatt
     5281 tcaattacaa tgaatgaatg tacggtatca tcgtgtgtga actactgctg taaaatgtgc
     5341 tgatcctcct gccccaaacc cacctctcca cttgattgcc cactgtaaga cctgtcagta
     5401 tccagaaaga gctgggctct gctttcctca aaactcagca agccaacaga gaaattagat
     5461 gctatcggtt tgatattttt aaaaaaaaat atttctgaga attatcttag ggctcagatt
     5521 cagcctcttg gctttccacc cttacatgtc agatcctaag ggctaaagga tggatgatgc
     5581 tacagtcatc cctggctgga agagaggtgg actggaagct agaagaaaga tgcgctccat
     5641 tttcactctc tcgccagctt tggaagtcat actttgctcc tgttctttgc ccaacagaac
     5701 tcgggtgatt cttgctcagt taccatgctg cccaactcca gtacatacct gcccagcagc
     5761 cccactccta gctccatgcc tttaggagtg aaattcattg gatacatgta gattcatctt
     5821 tgatgtaagg ggcttaaagg cattgaactt tgcacatgga gctataaagt gggcgtattt
     5881 aagctaaata tgttgttgag cagtgcggaa gcagaaatca agacagtttg aacttttaag
     5941 aaaggagagg aagagccgtt tggccagata aaaagatgtt aaaa
//
