LOCUS       NM_028007               3355 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus integrin alpha FG-GAP repeat containing 1 (Itfg1),
            mRNA.
ACCESSION   NM_028007
VERSION     NM_028007.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3355)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   2  (bases 1 to 3355)
  AUTHORS   Fiscella,M., Perry,J.W., Teng,B., Bloom,M., Zhang,C., Leung,K.,
            Pukac,L., Florence,K., Concepcion,A., Liu,B., Meng,Y., Chen,C.,
            Elgin,E.C., Kanakaraj,P., Kaufmann,T.E., Porter,J., Cibotti,R.,
            Mei,Y., Zhou,J., Chen,G., Roschke,V., Komatsoulis,G., Mansfield,B.,
            Ruben,S., Sanyal,I. and Migone,T.S.
  TITLE     TIP, a T-cell factor identified using high-throughput screening
            increases survival in a graft-versus-host disease model
  JOURNAL   Nat Biotechnol 21 (3), 302-307 (2003)
   PUBMED   12598909
REFERENCE   3  (bases 1 to 3355)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 3355)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
REFERENCE   5  (bases 1 to 3355)
  AUTHORS   Ko,M.S., Threat,T.A., Wang,X., Horton,J.H., Cui,Y., Wang,X.,
            Pryor,E., Paris,J., Wells-Smith,J., Kitchen,J.R., Rowe,L.B.,
            Eppig,J., Satoh,T., Brant,L., Fujiwara,H., Yotsumoto,S. and
            Nakashima,H.
  TITLE     Genome-wide mapping of unselected transcripts from extraembryonic
            tissue of 7.5-day mouse embryos reveals enrichment in the t-complex
            and under-representation on the X chromosome
  JOURNAL   Hum Mol Genet 7 (12), 1967-1978 (1998)
   PUBMED   9811942
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DN175510.1, BP765330.1, AK132242.1, AK141948.1 and AV257002.1.
            
            On Nov 19, 2009 this sequence version replaced NM_028007.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660821.161294.1,
                                           SRR1660821.176218.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                DN175510.1         14-53
            41-56               BP765330.1         48-63
            57-781              AK132242.1         2-726
            782-2530            AK132242.1         728-2476
            2531-3334           AK141948.1         2504-3307
            3335-3355           AV257002.1         227-247
FEATURES             Location/Qualifiers
     source          1..3355
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 41.61 cM"
     gene            1..3355
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /note="integrin alpha FG-GAP repeat containing 1"
                     /db_xref="GeneID:71927"
                     /db_xref="MGI:MGI:106419"
     exon            1..416
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     CDS             212..2044
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /note="T-cell immunomodulatory protein; integrin-alpha
                     FG-GAP repeat-containing protein 1; linkin"
                     /codon_start=1
                     /product="T-cell immunomodulatory protein precursor"
                     /protein_id="NP_082283.2"
                     /db_xref="CCDS:CCDS40424.1"
                     /db_xref="GeneID:71927"
                     /db_xref="MGI:MGI:106419"
                     /translation="MAAGRLPSARAVLAPLFLGLALLSVGPAPARALHNVTAELFGAE
                     AWGTLAAFGDLNSDKQTDLFVLRERNDLIVFLADQSAPYFKPKVKVSLKTLSALVTSV
                     VPGDYDGDSQMDVLLTYFPQNHTNSELGAVIFWGQNQTLDPKNMTILNRTFHDQPLIM
                     DFNGDLIPDVFGITNESSQPQILLGGDLSWHPALTTKSKMRDPHSHAFIDLTEDFTAD
                     LFLTTLTASNAFQFEIWENLGGNFSIHSVFEKPKNLVVVGQSAFADFDGDGHMDHLLP
                     GCEDKDCQKSAIYLMRSGTGQWVPVLQDFSNKGTLWGFVPFVHEEQPTTIPIPLTLHI
                     GDYNMDGYPDALAILKNTSGSNQQAFLLENVPCNNASCEEVHRMFKVYWDLAGLNLIK
                     DAIVATFFDIYEDGILDIIVLSKGYTKNDVAIHTLKNNFEADAYFVKVIVLSGLCSND
                     CPRKITPFGVNQPGPYIMYTTVDANGYLKNGSAGQLSQSAHLALQLPYNVLGLGRSAN
                     FLDHLFVGIPRPSGEKSIRKQEWTAIIPNSQLIVIPYPHNVPRSWSAKLYLTPSNIVL
                     LTAVALIGVCIFILAIIAILHWQEKKADDREKRQEAHRFHFDAM"
     exon            417..489
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            490..635
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            636..693
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            694..768
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            769..863
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            864..925
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            926..1007
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            1008..1102
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            1103..1275
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            1276..1426
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1535
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            1536..1579
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            1580..1658
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            1659..1783
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            1784..1866
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            1867..1984
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     exon            1985..3355
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2179..2184
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /note="hexamer: AATAAA"
     polyA_site      2202
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /note="major polyA site"
     regulatory      2354..2359
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /note="hexamer: AATAAA"
     polyA_site      2373
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /note="major polyA site"
     regulatory      3208..3213
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /note="hexamer: TATAAA"
     polyA_site      3225
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
     regulatory      3317..3322
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /note="hexamer: AATAAA"
     polyA_site      3342
                     /gene="Itfg1"
                     /gene_synonym="2310047C21Rik; Cda08; D8Wsu49e"
                     /note="major polyA site"
ORIGIN      
        1 cacgacagcc ggaagtgagt tcccgggcag acgccgccct agctcctcgg cgtcttggtc
       61 gtcggagaaa cagccccagg gcagcgtgag agtgcagcga ggggctgccc gtgaggccgc
      121 accccgagtc ttttctcggt cggccggtca gtcgcacggt gctttgcggc tgccgtcaag
      181 cgcggcggag gccggccggg ccgaaggcgc catggcggca ggccggcttc ctagcgccag
      241 ggcggtgctg gccccgctgt tcttggggct cgcgctgctg agcgttgggc ctgccccggc
      301 gcgggctctg cacaacgtca cggccgagct ctttggggct gaggcctggg gcaccctggc
      361 ggccttcggt gacctcaact ccgacaaaca gacggacctc ttcgtgctgc gggaaagaaa
      421 tgacttaatt gtcttcttgg cagatcagag tgcaccctat tttaaaccca aggtaaaggt
      481 atccctgaag actttgagtg cgttggtaac aagtgtggtc cctggtgatt atgatgggga
      541 ttcacaaatg gatgtcctgc tcacatactt tccccaaaat cataccaaca gtgaactagg
      601 agctgttatc ttttggggac aaaatcaaac attagatcct aaaaacatga ccatactcaa
      661 taggactttt catgaccaac cactgattat ggacttcaat ggtgatctaa ttcctgatgt
      721 gtttggtatc acaaatgaat ccagccaacc gcagatactg ctaggaggag atttatcatg
      781 gcatcctgcc ttgaccacta agagtaaaat gcgagatcca cattcccatg catttattga
      841 tctgactgaa gattttacag cagatttatt cctcacgaca ttgactgcct ctaatgcctt
      901 ccagtttgag atatgggaaa atttgggtgg aaacttctct atccatagtg tctttgaaaa
      961 acctaaaaat ctggtggtgg ttggacagtc agcatttgca gactttgatg gagatggaca
     1021 catggatcac ttgctgccag gctgtgaaga taaggactgt cagaaaagtg ccatatattt
     1081 aatgagatct ggaacaggac agtgggttcc tgtgcttcag gattttagca ataagggtac
     1141 actctggggc tttgtgccat ttgtgcatga agaacaacca accacaatac caatcccact
     1201 cacacttcac attggagact acaacatgga cggctaccca gatgctctgg ctatattgaa
     1261 gaatacatct ggaagcaatc agcaagcctt tttactggag aacgtcccat gcaataatgc
     1321 gagctgcgaa gaagtgcatc ggatgtttaa agtctactgg gacctagcag gcctaaatct
     1381 aatcaaagac gccatagttg ccaccttttt tgatatttat gaagatggaa tcttggacat
     1441 tatagtcctc agtaaaggat acaccaagaa tgatgttgcc atccatacac tcaaaaataa
     1501 ctttgaggca gatgcttact ttgttaaagt cattgttctt agtggtctat gttctaatga
     1561 ctgtcctcgt aagataacac cttttggagt aaatcagcct ggaccttata tcatgtacac
     1621 aacagtagat gcaaatggat atctgaaaaa cggctcagct ggacagctca gccagtcagc
     1681 acacttagct cttcagctac cttacaatgt acttggctta ggccgaagtg ccaatttcct
     1741 ggatcatctt tttgttggta ttccccgtcc atctggagag aagtctataa gaaaacaaga
     1801 gtggacagca atcattccaa attcccagct gattgtcatt ccatatcctc acaatgtccc
     1861 tcgaagctgg agtgccaaat tgtacctgac accaagtaac attgtcctgc tgactgcggt
     1921 agccctcatt ggagtctgca tttttatcct ggcaataatc gccattttac attggcagga
     1981 aaagaaagcc gatgacagag aaaaacgaca ggaagcacat cggtttcatt ttgatgctat
     2041 gtgactttgc tgaagtagta catcctggaa atcacttgat tagtgaaaca ttaaattttg
     2101 actcctagtt taaaaaaaat gatggatctg agatatttat aaattatgcc ttccttgtca
     2161 attattggaa aatactgaaa taaatatggc ctgaatatct cataaagtct gttttaagca
     2221 ctttgtatat aataatttag gttcttaatt tagcagcact gagcatttgt gttcctttgt
     2281 ggaatgtgtt gcatgtactt ggtgtatctg tgtttacaat gttgttagac tgaggatggt
     2341 gaaaggacgt gtaaataaaa actatttaaa tgacctgtgg ccagggcgtt gttctgccta
     2401 aattgatctt gtttttatct ttaaaatgca tactttcaca aatatgtgcc agataaagtt
     2461 attcaagtaa cattcttcac tgcagatcag actgctcatg cgtggcacag aatgaaacta
     2521 aatagccagg ctttggaatc ataggaggac agcttgcctt agatgcctgg ttctacaact
     2581 tagagttatc tgaatatggc tgctgcttag cgtctccgta agcctcagtt ttgtttgtat
     2641 gatgaggcta atatgcttgt tcacttgagt tgtcatgagc atacattgta tgatgtacat
     2701 gatgtactta gctcagtgtc tgagcataca gaaagcactc gtcaagcagc tgctgtcatg
     2761 attgctactg taggtgatct tattctacta ctgtatacaa tggattgtca ccgaagacat
     2821 aaggactctt tggaaaactt aaattattgg tggtacatat cttacatagt taacttgttt
     2881 aactagctct aatactatcc aagagtaaat gtatcctgaa agctggtatt tgaatactaa
     2941 tccttgcaca gtaacataaa tgatttgctc tcttgaaaga aagctgatag aggcaaactc
     3001 ttcaggtgcc agcatgccat acagttctgt ctcaaaagac gggaaaggtc tgtcccattt
     3061 ctacagacct caggtttcat gttagaaact tcacattgcc aacatttact ttaaaattat
     3121 ttaaatctag atttcaggag agaggtgata aaattattat caaagctaac aatatgctga
     3181 ttgttaagac atgctgtggc tgtaaaatat aaaattcctc tggaacagtt ttgtttgtgt
     3241 tattttcctc actgcgattc actggagggc atgtgctcct ttttatttct atctaagcat
     3301 gttaatatac cttcttaata aatactcctt actgaataaa aacgctgtgg caagc
//
