LOCUS       NM_001101598            1088 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus isochorismatase domain containing 2a (Isoc2a), mRNA.
ACCESSION   NM_001101598 XM_001475261 XM_973921
VERSION     NM_001101598.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1088)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BG404719.1, BC158139.1 and AC157563.12.
            
            On or before Sep 4, 2008 this sequence version replaced
            XM_001475261.1, XM_973921.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158139.1, SRR7345562.1318139.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               BG404719.1         1-100
            101-725             BC158139.1         1-625
            726-733             AC157563.12        62257-62264
            734-872             BC158139.1         634-772
            873-1088            AC157563.12        62404-62619
FEATURES             Location/Qualifiers
     source          1..1088
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 2.82 cM"
     gene            1..1088
                     /gene="Isoc2a"
                     /gene_synonym="Isoc2"
                     /note="isochorismatase domain containing 2a"
                     /db_xref="GeneID:664994"
                     /db_xref="MGI:MGI:3609243"
     exon            1..141
                     /gene="Isoc2a"
                     /gene_synonym="Isoc2"
                     /inference="alignment:Splign:2.1.0"
     exon            142..288
                     /gene="Isoc2a"
                     /gene_synonym="Isoc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             151..771
                     /gene="Isoc2a"
                     /gene_synonym="Isoc2"
                     /note="isochorismatase domain-containing protein 2A,
                     mitochondrial"
                     /codon_start=1
                     /product="isochorismatase domain-containing protein 2A
                     precursor"
                     /protein_id="NP_001095068.1"
                     /db_xref="CCDS:CCDS51978.1"
                     /db_xref="GeneID:664994"
                     /db_xref="MGI:MGI:3609243"
                     /translation="MAAARASLGRILPESSILFLCDLQEKFRPSIAYFPQIVSVAARM
                     LKVARLLDVPILLTEQYPEGLGPTVPELGAQGIRPVSKTCFSMVPALQKELDGRSQLQ
                     SVLLCGIETQACILNTALDLLHRGLQVHVVVDACSSRSQVDRLVALARMRQSGAFLAT
                     SESLILQLVRDASHPQFKEIQKIIKEPVPDSGLLSLFQGQSPLTSC"
     exon            289..498
                     /gene="Isoc2a"
                     /gene_synonym="Isoc2"
                     /inference="alignment:Splign:2.1.0"
     exon            499..569
                     /gene="Isoc2a"
                     /gene_synonym="Isoc2"
                     /inference="alignment:Splign:2.1.0"
     exon            570..687
                     /gene="Isoc2a"
                     /gene_synonym="Isoc2"
                     /inference="alignment:Splign:2.1.0"
     exon            688..1088
                     /gene="Isoc2a"
                     /gene_synonym="Isoc2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1059..1064
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Isoc2a"
                     /gene_synonym="Isoc2"
                     /note="hexamer: AGTAAA"
     polyA_site      1088
                     /gene="Isoc2a"
                     /gene_synonym="Isoc2"
                     /note="major polyA site"
ORIGIN      
        1 agacacgtaa ggggagcaga cctcgtgtcc aaagtgggca aaacggtgac ccagcccgga
       61 actagtgaca gtccagtggg ggagagtgcg ctgaagggac ctagtggagg gacttgctgc
      121 actcgaacct ggtaccgccg gccctaggaa atggcagcag ccagggctag cctgggccgg
      181 atcctcccag agtcctccat cctgttccta tgtgacttac aggagaagtt tcgccctagc
      241 atagcctact tcccacagat cgtgtcagtg gctgctcgga tgcttaaggt ggcccggctg
      301 ctagatgtcc ccattttgct gacagagcag tacccagaag gcctgggccc cacagttcct
      361 gagctgggcg ctcagggcat tcggccagtg agtaagacct gcttcagtat ggtgcccgcc
      421 ttacagaagg agctagatgg caggtcccag cttcagtctg tgctactctg tggcatcgag
      481 acccaagcct gcatcttgaa cacagctctg gacctacttc accggggact gcaggttcat
      541 gtagtggtgg atgcctgttc ttctcgaagc caggttgacc ggctggtggc actggcccgg
      601 atgagacaga gtggagcttt cctcgccacc agcgaatcgc tcattctgca gctcgtgagg
      661 gatgcctccc acccccagtt caaggagatt cagaagatca ttaaggagcc ggtcccggac
      721 agcgggctgc tgagcctctt ccaaggccag agccccctca cctcttgctg aactccaggc
      781 catgactgag acaacagact tactctgtcg tcggtgggag catctgccct acgggagagg
      841 aggggtgaac tgctggtcct ggaaatgcaa atgagactcc tgagtgctag aaggggtggg
      901 gatgggggta gggagtgggg ggggtggggg ggtggagggg gtgggggggt ggaggggggg
      961 cgggggttga ctgaagagag gtggagaggg gactctgctt aggtctacct cataagcaaa
     1021 gggcaaaaaa agtgtcacag actgggaccc atattctgag taaacattga tgtgactgtg
     1081 aactgaaa
//
