LOCUS       NM_025478               2563 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus isochorismatase domain containing 1 (Isoc1), mRNA.
ACCESSION   NM_025478
VERSION     NM_025478.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2563)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   2  (bases 1 to 2563)
  AUTHORS   Rainger,J., Keighren,M., Keene,D.R., Charbonneau,N.L.,
            Rainger,J.K., Fisher,M., Mella,S., Huang,J.T., Rose,L., van't
            Hof,R., Sakai,L.Y., Jackson,I.J. and Fitzpatrick,D.R.
  TITLE     A trans-acting protein effect causes severe eye malformation in the
            Mp mouse
  JOURNAL   PLoS Genet 9 (12), e1003998 (2013)
   PUBMED   24348270
REFERENCE   3  (bases 1 to 2563)
  AUTHORS   Quina,L.A., Wang,S., Ng,L. and Turner,E.E.
  TITLE     Brn3a and Nurr1 mediate a gene regulatory pathway for habenula
            development
  JOURNAL   J Neurosci 29 (45), 14309-14322 (2009)
   PUBMED   19906978
REFERENCE   4  (bases 1 to 2563)
  AUTHORS   Kikuchi,M., Hatano,N., Yokota,S., Shimozawa,N., Imanaka,T. and
            Taniguchi,H.
  TITLE     Proteomic analysis of rat liver peroxisome: presence of
            peroxisome-specific isozyme of Lon protease
  JOURNAL   J Biol Chem 279 (1), 421-428 (2004)
   PUBMED   14561759
REFERENCE   5  (bases 1 to 2563)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   6  (bases 1 to 2563)
  AUTHORS   Yang,J.S., Zheng,X.M. and Chen,S.S.
  TITLE     [Screening and identification of tumor related genes in early
            stages of transformed NIH3T3 cells associated with overexpressed
            PTPalpha]
  JOURNAL   Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 34 (5),
            601-607 (2002)
   PUBMED   12198563
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC158924.6.
            
            On Nov 17, 2006 this sequence version replaced NM_025478.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY035213.1, AK152763.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-316               AC158924.6         152410-152725       c
            317-436             AC158924.6         140880-140999       c
            437-640             AC158924.6         140556-140759       c
            641-757             AC158924.6         138841-138957       c
            758-2563            AC158924.6         132637-134442       c
FEATURES             Location/Qualifiers
     source          1..2563
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 33.71 cM"
     gene            1..2563
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
                     /note="isochorismatase domain containing 1"
                     /db_xref="GeneID:66307"
                     /db_xref="MGI:MGI:1913557"
     exon            1..316
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             11..904
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
                     /codon_start=1
                     /product="isochorismatase domain-containing protein 1"
                     /protein_id="NP_079754.2"
                     /db_xref="CCDS:CCDS29265.1"
                     /db_xref="GeneID:66307"
                     /db_xref="MGI:MGI:1913557"
                     /translation="MAAAEPSVAALAGGGVGAGAPSGGVPVLFCFSVFARPASVPHGA
                     GYDVLIQKFLSLYGDQLDMHRKFVVQLFAEEWGQYVDLPKGFAVSERCKLRLVPLQIQ
                     LTTLGNLTPPSTVFFCCDMQERFRPAIKYFGDIISVGQRLLQGARILGIPVIITEQYP
                     KGLGSTVQEIDLTGVKLVLPKTKFSMVLPEVEAALAEIPGVRSVVLFGVETHVCIQQT
                     ALELVGRGIEVHIVADATSSRSMMDRMFALERLARTGIIVTTSEAVLLQLVADKDHPK
                     FKEIQNLIKASAPESGLLSKV"
     exon            317..436
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            437..640
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            641..757
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            758..2563
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1938..1943
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
                     /note="hexamer: ATTAAA"
     regulatory      1942..1947
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
                     /note="hexamer: AAGAAA"
     polyA_site      1962
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
     polyA_site      1966
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
                     /note="major polyA site"
     regulatory      2002..2007
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
                     /note="hexamer: AATGAA"
     polyA_site      2030
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
     regulatory      2478..2483
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2504
                     /gene="Isoc1"
                     /gene_synonym="2610034N03Rik"
ORIGIN      
        1 cgcggggaac atggcggcgg cggagccctc ggtggccgcg ctggcgggcg gcggtgtggg
       61 cgcgggggcg ccgtcgggcg gcgtgccggt gctcttctgc ttctcggtgt tcgcgcggcc
      121 cgcgtcggtg ccccacggcg cgggctacga cgtgctcatc cagaagttcc tgagcctgta
      181 cggcgatcag ctcgacatgc accgcaaatt cgtggtgcag ctcttcgccg aggagtgggg
      241 tcagtacgtg gacctgccca agggcttcgc ggtgagcgag cgctgcaagc tgcgcctggt
      301 gccgctgcag atccagctta cgaccctggg aaatctcaca cctccgagca ctgtgttttt
      361 ctgctgtgac atgcaggaaa ggttccgtcc agccatcaaa tactttgggg acatcattag
      421 tgtgggacag agactgttgc aaggagctcg gatcttaggg attccagtta tcataacgga
      481 acaatacccc aaaggacttg gcagcaccgt tcaagaaatc gacttaacag gtgtgaaact
      541 ggttcttcca aagaccaagt tttctatggt gttacctgaa gtcgaagcag cgttagccga
      601 gattcctggc gtccggagtg tcgtgttgtt tggagtagaa acgcacgtgt gtatccagca
      661 aactgccctg gagctggtcg gccgaggcat cgaggttcac atcgtcgcgg acgccacctc
      721 ctcgagaagc atgatggaca ggatgtttgc tcttgagcgt cttgcccgca ctgggatcat
      781 cgtgaccact agtgaggctg tcctcctaca gctggtggct gacaaagacc acccgaagtt
      841 caaggaaatt cagaacctaa ttaaggcgag tgccccggag tcgggtctgc tttctaaagt
      901 gtaggagact tgaaggatca gggtcctcct tccctccagg cgatgagact gcaaaccaca
      961 caagcccttg tctccactag aactactatg tcaagtcaac agctccttct ttgcggctct
     1021 tagtaaccct tacctggcta gaccgttgtg tacaagtgtt tagttccaat gtcgaggctt
     1081 caggtgctgc ttctcttctt cttaacgagc ttttagttat taagacaaat taccatggag
     1141 gtgcctgtct cgtctatact gcatactctg accatatctt tccaaagtgc accctctggt
     1201 gaagtattct taaattgtgc actttaatgg gagaaaaaca aaaaaaaaca aacaaacaaa
     1261 caaaaaaacc cacgtaccac aatgatttga cctttctttt gttgtgaagc atcccttgtc
     1321 atgtcagtgt atacccagtg attttgcttc tcaggctgac tggccaatga ctcctgggtg
     1381 agaattgaga accaggactc tggctcgtgt atctcctcct ctctcagtgt tggagtcgct
     1441 gactgagtga ggtgcattgg cttaaggagc gcaaattatc ttcaatattg tgtatctgtc
     1501 ttgattgcat taattttctt attcctgtta cggtctttgt ggatgctctt cctatggata
     1561 acagtctatg ttaacatttt tcttccactg aatgttttcc ttgctccttg gttattttaa
     1621 acttgtaaac agatgggagt ggtttgcagt gctgggtcat tgacagaggt ttgcccaaac
     1681 atacagtctt tttgagtgca tcttttacta tacacaggaa ttggtggaga aagaaacact
     1741 aggtaaaatg tacccatatt cccctccaaa cattgttatg gctgacatca tcaaccagac
     1801 tcataggggt aatactgtgg tcattgttaa ccaatcaata aacttatttc catttcatac
     1861 tgataattac tcaaacatct ttttaatgtc tgttgtgata tgtggaacta tgtggaacat
     1921 tactctcttt gtataaaatt aaagaaaatg tataatgtgg gtgaaattgt tttgttttcc
     1981 atgactccat gaatattagt caatgaattg taatgagttc tcaaaggtaa cagatttgct
     2041 gtttgtttaa aatcattgga accttcaaag gaggggaatc ctctgcaggc ccagactgat
     2101 agcgttcctg cagggttttc ctgttagcac tgtagaaatg tgttctgtta tttgagcctt
     2161 ggtaaggcac cattgcctag tgttcttctt ggtgtgctca gttgttctca gcctctgggc
     2221 tgtgaccaca gatatatcac atatcagata tatcacatat cagatatatc acatatcaga
     2281 tatttgcatt aaaattcatg acagtagcaa aattacagtt atgaagtagc aacaaaaata
     2341 attttatggc tagggagtca ccacaaatga ggaacggaat taaagggttg cagcattagg
     2401 aaggttgaga gctgctgcct agaagatgag tccagaaaga agcatcatat tgttatccac
     2461 gttttaaaat aatttctaat aaatgtaagc tagtgttttt caaactttta ttatctggag
     2521 tgcttgctaa aatactgagt ttagcttctt cctctccctt cgt
//
