LOCUS       NM_177663               2901 bp    mRNA    linear   ROD 08-AUG-2024
DEFINITION  Mus musculus interferon stimulated exonuclease gene 20-like 2
            (Isg20l2), mRNA.
ACCESSION   NM_177663
VERSION     NM_177663.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2901)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 2901)
  AUTHORS   Diez-Roux,G., Banfi,S., Sultan,M., Geffers,L., Anand,S., Rozado,D.,
            Magen,A., Canidio,E., Pagani,M., Peluso,I., Lin-Marq,N., Koch,M.,
            Bilio,M., Cantiello,I., Verde,R., De Masi,C., Bianchi,S.A.,
            Cicchini,J., Perroud,E., Mehmeti,S., Dagand,E., Schrinner,S.,
            Nurnberger,A., Schmidt,K., Metz,K., Zwingmann,C., Brieske,N.,
            Springer,C., Hernandez,A.M., Herzog,S., Grabbe,F., Sieverding,C.,
            Fischer,B., Schrader,K., Brockmeyer,M., Dettmer,S., Helbig,C.,
            Alunni,V., Battaini,M.A., Mura,C., Henrichsen,C.N.,
            Garcia-Lopez,R., Echevarria,D., Puelles,E., Garcia-Calero,E.,
            Kruse,S., Uhr,M., Kauck,C., Feng,G., Milyaev,N., Ong,C.K.,
            Kumar,L., Lam,M., Semple,C.A., Gyenesei,A., Mundlos,S., Radelof,U.,
            Lehrach,H., Sarmientos,P., Reymond,A., Davidson,D.R., Dolle,P.,
            Antonarakis,S.E., Yaspo,M.L., Martinez,S., Baldock,R.A., Eichele,G.
            and Ballabio,A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158233.2.
            
            On Mar 30, 2023 this sequence version replaced NM_177663.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK053778.1, SRR13861890.97965.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-305               AC158233.2         98607-98911
            306-1250            AC158233.2         99631-100575
            1251-1451           AC158233.2         106874-107074
            1452-2901           AC158233.2         107538-108987
FEATURES             Location/Qualifiers
     source          1..2901
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 38.78 cM"
     gene            1..2901
                     /gene="Isg20l2"
                     /gene_synonym="4930429N24"
                     /note="interferon stimulated exonuclease gene 20-like 2"
                     /db_xref="GeneID:229504"
                     /db_xref="MGI:MGI:2140076"
     exon            1..305
                     /gene="Isg20l2"
                     /gene_synonym="4930429N24"
                     /inference="alignment:Splign:2.1.0"
     exon            306..1250
                     /gene="Isg20l2"
                     /gene_synonym="4930429N24"
                     /inference="alignment:Splign:2.1.0"
     CDS             459..1565
                     /gene="Isg20l2"
                     /gene_synonym="4930429N24"
                     /codon_start=1
                     /product="interferon-stimulated 20 kDa exonuclease-like 2"
                     /protein_id="NP_808331.1"
                     /db_xref="CCDS:CCDS17459.1"
                     /db_xref="GeneID:229504"
                     /db_xref="MGI:MGI:2140076"
                     /translation="MSTILLNLDFGQPSKKAFGGNAKHQRFVKKRRFLEQKGFLNKKN
                     QPPNKVSKLNSEPPKKGETSRVDGILKILPCPKKKEAAASKRDSEQSKDKKAPLSWLT
                     PAPSKKTASVVSKIDLLGEFQSALPKTKSTQKKGSKKKSLKKKIATENSTQAQSKDKG
                     SKKKPLKKNAVPNSTQARSEDKCPTVPQNLPGKMVAIDCEMVGTGPKGRVSSLARCSI
                     VNYNGDVLYDEYVLPPCYIVNYRTRWSGIRKCHMVNATPFKTARSQILKILSGKVVIG
                     HAIHNDYKALQYFHPKSLTRDTSRIPLLNRKADCPENVTLSLKHLTKKLLSRDIQVGN
                     TGHSSVEDAQATMELYKLVEVEWEQHLAQNPPEN"
     exon            1251..1451
                     /gene="Isg20l2"
                     /gene_synonym="4930429N24"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..2901
                     /gene="Isg20l2"
                     /gene_synonym="4930429N24"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2879..2884
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Isg20l2"
                     /gene_synonym="4930429N24"
                     /note="hexamer: TATAAA"
     polyA_site      2901
                     /gene="Isg20l2"
                     /gene_synonym="4930429N24"
                     /note="major polyA site"
ORIGIN      
        1 gcactctgtt ccgcttcccg cggcccacca ccttcgagtt gtacctccac ggggcccgag
       61 gggccgggga gcgcatcccg cccccgcccc cacccacgcc gccgccgccg ccaccgccgt
      121 tcccgctgct cacgcactcc gagtcgctgg cctcgctgcc tgaggtgggg gcgctgcggg
      181 cgcgtgcgcg ccggccgcct tcccgttgtc gcccgcgttc ttgccgtccc ggcatacgtc
      241 ggcgcgcgcc tgcgcctgca tccggcttcg gacgcttgcg atcttagtgg ggaaccaact
      301 tggaggccta tggtgcggga atcaggatta ctttgtcccc aaggctgatt gcagacctcc
      361 acatgttgaa ctatgggatt ccacagagga tgagcctctc atccttttgc tatcagtgag
      421 ccattcttcc cagcttcctc ccaccatcca ctgatctcat gtctaccata ctcctgaatt
      481 tagactttgg gcaaccttcg aaaaaggcat ttggaggaaa tgccaaacat caacgctttg
      541 tcaagaagcg aaggttcttg gaacagaaag gatttctgaa taaaaagaac caacccccta
      601 acaaggtgtc taagttgaac tcagaacctc caaagaaagg ggaaacttca agagtagatg
      661 gcattttgaa gatccttcca tgcccaaaga agaaagaggc agctgcctcc aagagggact
      721 cagagcagtc caaagacaag aaagcaccat tgtcttggct gacccctgct ccttcaaaga
      781 agactgcttc tgttgtgtct aaaatagatt tgctagggga gtttcagagt gcccttccaa
      841 agactaagag cacccagaag aagggctcca agaagaagtc cttgaaaaag aaaattgcta
      901 cagagaactc cacccaagct cagtcaaagg ataaaggctc caagaagaag cccttgaaga
      961 aaaatgctgt accgaactcc acccaagctc gttctgaaga taagtgccct acagtccccc
     1021 aaaacttgcc agggaagatg gtggcaatag actgtgaaat ggtgggcaca ggacccaagg
     1081 gacgcgttag ttccctggct cgatgcagca ttgtaaatta caatggtgat gtgctgtacg
     1141 atgagtacgt cctccccccc tgctacatcg tcaactaccg gaccagatgg agtggcatcc
     1201 ggaagtgcca catggttaac gctacaccct ttaagactgc tcggagtcag atcttgaaga
     1261 tactctcagg gaaggtagtg atagggcatg ccattcacaa tgactacaaa gccctacagt
     1321 actttcatcc caagtccctc accagagaca cttcccggat accactcctc aaccggaagg
     1381 ctgactgccc agaaaatgtc actttgtcac tgaagcatct caccaagaag ctcctgagtc
     1441 gggacatcca ggttggaaat actggacatt cctcggtgga agatgcccag gccacaatgg
     1501 agctgtacaa gttggttgaa gttgaatggg aacagcacct ggcccagaat cctccagaaa
     1561 attagcaatc ccagggagac acatgcagta gaccaaccca cagttcttcc agcttctcac
     1621 ctgcagaagc tagaatcact ggggagaggg gcttggccag aggcttaata cccattgaaa
     1681 tttcatctca gctattttgg tcactgtgtg gttaagtgtc tcatggaaga ggagagcttt
     1741 catgttaaac ccacctctag gtcaggcagg tggctcagac ctgtaatccc agatacttgg
     1801 gaggctgaaa caggttatag atgtaaagtc tgcctggact acagaattaa ttctaggtca
     1861 gtgagaccct gtcctaacat aaaaagaggg ccaggggtaa agcccagcgc tagaacactt
     1921 acctagcatg cataaaccac taggtacagt ctccagcagt ggggtggggg agggtagaag
     1981 gaatggaata caaagtcatg aaccataact gtttacttct ttagagtgct aaccacatgt
     2041 cacagggtgc ttgtgccagt cagccttgac tttgaggaag caaggcacac cagggaaaac
     2101 agtgtcccac actaccttct ctatgggaca catgtcatag atatgtctcc ttttggtggg
     2161 gagtagggta aaggaattga gttgccaggg ctggcctcaa acacttgggc tcagatgact
     2221 tcttcctcag gcccgagagt agctgggact acaggtgtgt gttcaccact gtgcctagtt
     2281 cttttatttt ttttattttt tttggttttt cgagacaggg tttctctgta tggccctggc
     2341 tgtcctggaa ctcactctgt agaccacgct ggcctcaaac tcagaaatcc ccctgcctct
     2401 gcctcccgag tgctgggatc aaaggtgttg cgccaccacg cccagcatgg ttcttttaat
     2461 tttatgggat tttttgttct aaagtaaata gcagtatctt ttcactttca gacaagtcct
     2521 gattggagct cagcataatg gtctgtaatc tcaggactct ggaggccaag gcagggagat
     2581 caaaagttta agaccaatct gagtgcatag aaaaagctct gggtcagaga agtagaaaca
     2641 gagaaggaaa gaattttgtg gttgcttgct gaattttata gccacgttac atagcactga
     2701 ctaacagtgt ttacttaatt taggttccac ttagtttaaa aagaatttgt atagttttaa
     2761 tcgtctttca gccttttcag cctttcacct tgcaaatgca gcctcttagt tcatacgatt
     2821 ctttttatgg atttttataa tagaaaactg gtgggtttgt tttttgtttt tttttacata
     2881 taaagatcta tttttatttt a
//
