LOCUS       NM_001408942            6371 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus IQ motif and Sec7 domain 1 (Iqsec1), transcript
            variant 4, mRNA.
ACCESSION   NM_001408942 XM_006505985
VERSION     NM_001408942.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6371)
  AUTHORS   Brisevac,D., Scholz,R., Du,D., Elagabani,M.N., Kohr,G. and
            Kornau,H.C.
  TITLE     The small GTPase Arf6 is dysregulated in a mouse model for fragile
            X syndrome
  JOURNAL   J Neurochem 157 (3), 666-683 (2021)
   PUBMED   33125726
REFERENCE   2  (bases 1 to 6371)
  AUTHORS   Fukaya,M., Sugawara,T., Hara,Y., Itakura,M., Watanabe,M. and
            Sakagami,H.
  TITLE     BRAG2a Mediates mGluR-Dependent AMPA Receptor Internalization at
            Excitatory Postsynapses through the Interaction with PSD-95 and
            Endophilin 3
  JOURNAL   J Neurosci 40 (22), 4277-4296 (2020)
   PUBMED   32341099
  REMARK    GeneRIF: BRAG2a Mediates mGluR-Dependent AMPA Receptor
            Internalization at Excitatory Postsynapses through the Interaction
            with PSD-95 and Endophilin 3.
REFERENCE   3  (bases 1 to 6371)
  AUTHORS   Chomphoo,S., Sakagami,H., Kondo,H. and Hipkaeo,W.
  TITLE     Discrete localization patterns of Arf6, and its activators EFA6A
            and BRAG2, and its effector PIP5kinasegamma on myofibrils of
            myotubes and plasma membranes of myoblasts in developing skeletal
            muscles of mice
  JOURNAL   Acta Histochem 122 (3), 151513 (2020)
   PUBMED   32059926
REFERENCE   4  (bases 1 to 6371)
  AUTHORS   Ansar,M., Chung,H.L., Al-Otaibi,A., Elagabani,M.N.,
            Ravenscroft,T.A., Paracha,S.A., Scholz,R., Abdel Magid,T.,
            Sarwar,M.T., Shah,S.F., Qaisar,A.A., Makrythanasis,P.,
            Marcogliese,P.C., Kamsteeg,E.J., Falconnet,E., Ranza,E.,
            Santoni,F.A., Aldhalaan,H., Al-Asmari,A., Faqeih,E.A., Ahmed,J.,
            Kornau,H.C., Bellen,H.J. and Antonarakis,S.E.
  TITLE     Bi-allelic Variants in IQSEC1 Cause Intellectual Disability,
            Developmental Delay, and Short Stature
  JOURNAL   Am J Hum Genet 105 (5), 907-920 (2019)
   PUBMED   31607425
REFERENCE   5  (bases 1 to 6371)
  AUTHORS   Kinoshita-Kawada,M., Hasegawa,H., Hongu,T., Yanagi,S., Kanaho,Y.,
            Masai,I., Mishima,T., Chen,X., Tsuboi,Y., Rao,Y., Yuasa-Kawada,J.
            and Wu,J.Y.
  TITLE     A crucial role for Arf6 in the response of commissural axons to
            Slit
  JOURNAL   Development 146 (3) (2019)
   PUBMED   30674481
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6371)
  AUTHORS   Scholz,R., Berberich,S., Rathgeber,L., Kolleker,A., Kohr,G. and
            Kornau,H.C.
  TITLE     AMPA receptor signaling through BRAG2 and Arf6 critical for
            long-term synaptic depression
  JOURNAL   Neuron 66 (5), 768-780 (2010)
   PUBMED   20547133
REFERENCE   7  (bases 1 to 6371)
  AUTHORS   Schilling,K. and Oberdick,J.
  TITLE     The treasury of the commons: making use of public gene expression
            resources to better characterize the molecular diversity of
            inhibitory interneurons in the cerebellar cortex
  JOURNAL   Cerebellum 8 (4), 477-489 (2009)
   PUBMED   19554387
REFERENCE   8  (bases 1 to 6371)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   9  (bases 1 to 6371)
  AUTHORS   Trinidad,J.C., Specht,C.G., Thalhammer,A., Schoepfer,R. and
            Burlingame,A.L.
  TITLE     Comprehensive identification of phosphorylation sites in
            postsynaptic density preparations
  JOURNAL   Mol Cell Proteomics 5 (5), 914-922 (2006)
   PUBMED   16452087
REFERENCE   10 (bases 1 to 6371)
  AUTHORS   Takahashi,Y., Miyata,M., Zheng,P., Imazato,T., Horwitz,A. and
            Smith,J.D.
  TITLE     Identification of cAMP analogue inducible genes in RAW264
            macrophages
  JOURNAL   Biochim Biophys Acta 1492 (2-3), 385-394 (2000)
   PUBMED   11004510
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC121954.2.
            
            On Jul 5, 2022 this sequence version replaced XM_006505985.5.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.955332.1,
                                           SRR14777534.393527.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-237               AC121954.2         181562-181798       c
            238-529             AC121954.2         94300-94591         c
            530-1776            AC121954.2         89321-90567         c
            1777-1938           AC121954.2         80232-80393         c
            1939-2061           AC121954.2         77765-77887         c
            2062-2228           AC121954.2         76489-76655         c
            2229-2368           AC121954.2         71721-71860         c
            2369-2398           AC121954.2         71343-71372         c
            2399-2524           AC121954.2         70150-70275         c
            2525-2624           AC121954.2         69027-69126         c
            2625-2786           AC121954.2         68382-68543         c
            2787-2963           AC121954.2         67641-67817         c
            2964-3013           AC121954.2         63763-63812         c
            3014-6371           AC121954.2         59339-62696         c
FEATURES             Location/Qualifiers
     source          1..6371
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 40.16 cM"
     gene            1..6371
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /note="IQ motif and Sec7 domain 1"
                     /db_xref="GeneID:232227"
                     /db_xref="MGI:MGI:1196356"
     exon            1..237
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /inference="alignment:Splign:2.1.0"
     CDS             161..3514
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /note="isoform d is encoded by transcript variant 4; IQ
                     motif and SEC7 domain-containing protein 1"
                     /codon_start=1
                     /product="IQ motif and SEC7 domain-containing protein 1
                     isoform d"
                     /protein_id="NP_001395871.1"
                     /db_xref="GeneID:232227"
                     /db_xref="MGI:MGI:1196356"
                     /translation="MLKFKAFCLDYWQFLCLQPLHGAYKSVEGEAPSSETGTSLDSPS
                     AYHQGPLVPGSSLSPDHYEHTSVGAYGLYAGPGPQQRTRRPRLQHSTSVLRKQAEEEA
                     IKRSRSLSESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERL
                     RSSMSENRMSRRIVLSNMRMQFSFEGPEKVHSSYFEGKQVSVTNDGSQLGALVPSECG
                     DLSDPALKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHSEEVPASDTA
                     RARDTEPKPGLHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDL
                     RLRSGGAAQDYWALAHKEDKADTDTSCRSTPSLERPEPRLRVEHLPLLTIEPPSDSSV
                     ELSDRSDRSSLKRQSAYERSLGGQQGSPKHGPHGGPPKGLPREEPELRPRPPRPLESH
                     LAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYH
                     KETRNSWDSPAFSNDVIRKRHYRIGLNLFNKKPEKGIQYLIERGFVPDTPVGVAHFLL
                     QRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQ
                     KVERLIEAFSQRYCVCNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLE
                     DFVKNLRGVDDGEDIPRETLIGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSL
                     HHGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKN
                     SVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSAVPGADIKVLINFNAPNPQDRKKFT
                     DDLRESVAEVQEMEKHRIESELEKQKGVVRPSMSQCSSLKKESGNGTLSRACLDDSYA
                     SGEGLKRSALSSSLRDLSEAGKRGRRSSAGSLESNVEGSIISSPHMRRRATSTRECPS
                     RPPQPVPNSSSLLGSLFGSRRGKPPPQAHPPSAPPPAPPHAHHPGPSEGPLHGHHAQY
                     CHAQQNPPPYHHHHHYHPPPHLQHTHQYHHGPHGGHPPYGAHAHSHPPLPTAHPGHAG
                     HSAHHHGQPPAPPPPTSSKAKPSGISTVV"
     exon            238..529
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /inference="alignment:Splign:2.1.0"
     exon            530..1776
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /inference="alignment:Splign:2.1.0"
     exon            1777..1938
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /inference="alignment:Splign:2.1.0"
     exon            1939..2061
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /inference="alignment:Splign:2.1.0"
     exon            2062..2228
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /inference="alignment:Splign:2.1.0"
     exon            2229..2368
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /inference="alignment:Splign:2.1.0"
     exon            2369..2398
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /inference="alignment:Splign:2.1.0"
     exon            2399..2524
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /inference="alignment:Splign:2.1.0"
     exon            2525..2624
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /inference="alignment:Splign:2.1.0"
     exon            2625..2786
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /inference="alignment:Splign:2.1.0"
     exon            2787..2963
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /inference="alignment:Splign:2.1.0"
     exon            2964..3013
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /inference="alignment:Splign:2.1.0"
     exon            3014..6371
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5564..5569
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /note="hexamer: AATACA"
     polyA_site      5589
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /note="major polyA site"
     regulatory      6350..6355
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
                     /note="hexamer: AATAAA"
     polyA_site      6371
                     /gene="Iqsec1"
                     /gene_synonym="BRAG2; cI-43; D6Ertd349e"
ORIGIN      
        1 gtattggagg cgcgcactgt gtgagctgta ctaggcaagg ctgggccatg tgagtggggg
       61 ccgcggcagg gaccagcggc caggcctcca cctcctagca gccccttgct gtgtctctct
      121 ggagacacca ctgcagtcca ctagagactg gaaagtgaaa atgctcaagt tcaaggcctt
      181 ttgcctggat tactggcagt tcctgtgcct gcagccgttg catggggcct ataaaagtgt
      241 tgagggcgag gcccccagca gcgagactgg cacatcgctg gacagcccct cagcctacca
      301 tcagggtccc ctggtacctg gttccagcct gagtccagac cactacgagc acacatcagt
      361 gggcgcctat gggctgtacg cagggccagg accacaacag cgcacacgga ggccccggct
      421 gcagcactcg acctcagtcc tgcgcaagca ggctgaggag gaggccatca agcgctctcg
      481 gtcactctct gagagctatg agctctcttc agatctgcaa gacaagcagg tggaaatgct
      541 agaacgcaag tatgggggac gcctcgtgac ccgccatgca gcccgcacca tccagacggc
      601 gttccgccaa taccagatga acaagaactt tgagcgcctg cgcagctcca tgtcggagaa
      661 ccgcatgtca cgtcgcattg tgctgtccaa catgaggatg cagttctcct ttgagggccc
      721 cgagaaggtg cacagctcct actttgaggg aaagcaggtc tctgtgacta atgatggctc
      781 ccagctgggg gccctggtgc catcagaatg tggagacctt agtgacccag ccctcaagtc
      841 tccagccccc tccagtgact ttgcagatgc catcacggaa ctggaggatg ccttctccag
      901 gcaggtgaaa tccctggctg aatccatcga tgatgccctc aattgccgca gcctacacag
      961 tgaggaggta ccagcctcag acacggcccg ggctcgggac actgagccca aaccaggtct
     1021 acatggcatg gaccaccgca aactggatga gatgacagcc tcgtatagtg atgtgaccct
     1081 ctacattgat gaggaagagc tgtcaccacc gcttccactc tcacaggctg gcgatcggcc
     1141 ctccagcaca gagtcggacc tgcggctgag gtctgggggt gcagcccagg actactgggc
     1201 cttggcccac aaagaggaca aggctgacac ggacacaagc tgccgaagca caccatcact
     1261 ggagcggcca gagccacggc tgcgggtgga gcacctgccc ctgcttacca ttgagccacc
     1321 cagtgatagc tccgtggaac tcagtgaccg ctcagatcgc agctcactca agaggcagag
     1381 tgcctatgag cgcagcctcg gtgggcagca gggcagcccc aagcatggcc cccacggtgg
     1441 cccccccaaa ggcctcccca gggaggaacc tgaattgcgg cctcggcccc ccagacctct
     1501 tgagagtcac ctagccatca atggttcagc caaccggcag agcaaatctg agtctgacta
     1561 ctcagatggg gacaatgaca gcatcaacag cacctccaac tccaatgaca ccataaactg
     1621 cagctctgag tcctcatcac gggacagcct gcgggaacag acactcagca agcagacata
     1681 ccacaaggag acccgcaaca gctgggactc tccagctttc agcaacgatg tcatccgtaa
     1741 gaggcattac cgaattggcc taaatctctt caacaagaag cctgagaagg gcatccagta
     1801 tctcattgag cgcggcttcg tgcccgacac gccagtggga gtggcccact tcctgctgca
     1861 gcgcaagggc ctcagccgcc agatgatcgg tgagttcctg ggaaaccggc agaagcagtt
     1921 caaccgtgat gtgctcgact gtgttgtgga cgagatggac ttctctgcca tggagctaga
     1981 tgaagccctc cggaagttcc aggcacacat ccgagtccaa ggggaggctc agaaagtgga
     2041 gcggctcatc gaggcattca gccagcggta ctgtgtctgc aacccagggg tggtgcgaca
     2101 gttccggaac ccagacacca tcttcatcct ggccttcgcc atcatcctgc tcaacacaga
     2161 catgtacagc cccaatgtca agccagagcg caaaatgaag ctggaggact ttgtcaagaa
     2221 cctccgaggt gtggatgacg gtgaagacat tccccgggag acgctaattg ggatctatga
     2281 gcgaatccgt aagcgagaac tgaagaccaa cgaggaccac gtgtcccagg tgcagaaggt
     2341 tgagaagctc atcgtgggca agaagccgat tggatccctg catcatggtc ttggctgtgt
     2401 gctgtctctt ccccatcgac gactagtctg ctactgccgg ctttttgaag ttcctgaccc
     2461 caacaaaccc cagaagctgg gactacacca gcgagagatc ttcctgttta atgacctcct
     2521 ggtggtcacc aagatcttcc agaagaagaa gaactcggtg acatacagct tccggcagtc
     2581 cttctccctc tacggcatgc aggtcctgct cttcgagaac cagtactatc ccaatggcat
     2641 ccggctgacg tctgctgtcc ctggagcaga catcaaagtg ctaataaact tcaacgctcc
     2701 caatcctcag gaccggaaga agttcactga cgacctgcgg gagtctgtcg ctgaagtgca
     2761 agagatggag aaacaccgaa tagagtcgga gctcgagaag cagaaaggtg tcgtgcggcc
     2821 cagcatgtca cagtgctcca gcctcaaaaa ggagtcaggc aacgggacac tgagcagggc
     2881 ttgcctggat gacagctatg ccagtggcga gggcctcaag cgcagcgccc tcagcagctc
     2941 actgagagac ctctcagaag cggggaagcg agggcgtcgc agcagtgcgg gatcgctaga
     3001 gagcaatgtg gaaggctcca tcattagcag tcctcacatg cgccggagag cgacctcaac
     3061 acgagagtgc ccatctcgcc ccccccagcc cgtgcctaac tcctcctctc tcctgggttc
     3121 tttgtttggg agcaggagag ggaagccccc tccccaggcc cacccaccct cagcccctcc
     3181 cccagcaccc cctcacgccc atcaccctgg gccctcagaa ggcccactgc atggacatca
     3241 tgcacagtac tgccatgcac agcagaatcc tccgccctat caccaccacc accactacca
     3301 cccacccccc cacctgcagc acacccacca gtaccaccat ggcccacacg gcgggcaccc
     3361 cccgtatggg gcccatgcac acagccaccc gcctctgccc acagctcacc ctggtcatgc
     3421 agggcactca gcgcatcatc atgggcagcc ccctgcccca ccgcccccca ccagcagcaa
     3481 ggccaagccc agcggcatca gcacagttgt gtagacagcc caggcagctg cctcccacac
     3541 accaggcaca cagaggccta ctaggcacca gcctcagacc agcccagggc accgctattg
     3601 ccactccctc tgccctcata gcctgggtgg gcctgtgggc ttgccttcca tggagcagag
     3661 ctccctctct ggcttagccc tggcacccag tcctcccttg gcccaaggct ggacctcagc
     3721 caccactggc cttgacatgg cgctgaccaa ggagaagtgg aactgcctct caccctgtca
     3781 gccctcagcc cctcactcta cacacatctg aaaactcatc ctagcaaaga aaacataaga
     3841 tagaaaagtc agacaaagca gaaccaaccc ccagactggc tgtgttattg ttttgttatt
     3901 ggcagtgggc aaaataataa tataataata agtagacctg ataagggtga tgaaatacgt
     3961 aagtaaactt tatataatat aaatatataa atatataaat atatatatat acatactgta
     4021 taggtagtgt ttgtgtgtga aagataagca tttcatccac aaagctagca ctagggacct
     4081 cctaaggact gccacttagg tggcaggaag tcaatctaga tacatgtgtg agtagaccaa
     4141 aaaaccctgc tagaacaaac ccagatcctt ccatattttc atacaaagag actctctagc
     4201 ctggctgaaa ccttacacgc tcatgactca ctgtgccaag taacacagca cctgactgtc
     4261 taatacccca ctctgctctg tatagccccc tattttatta acagagtact attctaagta
     4321 accagtatta taactgctgt tatctccagt aagcaactag gcaaagtgca gtcaactcta
     4381 ccctagtact tggggcaacc agtctagagc tggctgtctc aggacctcag ccccacagat
     4441 ccctagacac tttatactgg ctgccataac tttgatctcc cacgctctac attccttccc
     4501 tctgtacatg gtgagccacg ctccccctcc cccacagtcc tcccagggcc cacgtggcag
     4561 aggggttcca ccccaacaca acgaccactc atcttccata acttcctcat ccagttccca
     4621 gccccagcag gcgggtggcg tgagcgctgg gcggcccagg gcggtgtgtg tgtcccgtgt
     4681 tgtgttctga gtggcaacag caatcactgt aattccatgc agccatgtgc tcgtgacccc
     4741 tgtgtcatca ttgcacctgg ccaatgagtg cttggccctg gccaggtgaa gcccccactg
     4801 cctctcatgg tccagtgagc tgccaggcct cacatgcccc agctgtgttc ttgtcgcttc
     4861 catgtgtgac accatgcact cccctggggc cacgtgctgc ccatgttcct gtgcctgagt
     4921 cacccacggg ctgtacttta cagtttcagc ccttccagcc accacagcct ccagtgctgt
     4981 gctcctaagc ctaggacccg aggactgcct gtggcctctg cctgcgcgga ggccctttca
     5041 gattggaagg agttgccgcc tgaccgtggg ctgcgtctag gaccttgtga gccaccgggg
     5101 cctgcccaac cacaagagag atcaggagcc ttctggccca tcaccactct gctggcctgc
     5161 ttgggtcacc catttccctc cccttcgtgt caccatcgtc gaggtcacgt accagcagat
     5221 ctgcaaactg agcactttgt atctgtgcag agagcaaatc ctgcaacatg gaggtcagcc
     5281 ttctgtctca cggtggctgg acccgcccgc cccatcctct gtcagcatgg ctcatctttc
     5341 tcttgtcatc tacgcagaaa gagaactgat caccatagtg tatctgactg gggccagctg
     5401 gcgaggagct gcccgcttca cagtgccccg agttccttgc ttatgctcca cgtactgtct
     5461 gtcctcagtt aaagaacact gtctgacaag gaagggggac tgtgctgcat gtgacctggc
     5521 accagtcgtg tggggctgtg ctctctgtat tgtacattta caaaatacac cagtgttact
     5581 gttggcaaat agttggagtg gtaacattaa atatgccggc tttttttttt ttcactctct
     5641 ctgagctagt ggtaagtcaa ccatgaactt gagattgttc tgaaaaagac atggctgtta
     5701 ggtacactct cactcttttt aaagggacac ttaggaacaa actcaaagga aggcccagtt
     5761 tatctggtag ggtggagtgg ggcctccctc tctccacagt gtcctgtatt ctcctggcta
     5821 gccagggctc tgggctcctc ccatgttatc tttcatgtgt cctagagaca agccgaggat
     5881 agtgggtgag ttctagggac caggcttcta agcatactca gtctttctct gagttcctaa
     5941 ttcaatatgt tatcggatca ggataatgag agcttgtgat cctgtgttgt tttacagaca
     6001 gggacctgtc ttcataggat gtgcctgggc ctgcaagtca cacagcagaa ctagcttgga
     6061 aagcataggc tttttttttt tttttttttt tttttttact gatgtccctt gttgcctgtt
     6121 attcagctat ggcattgagg cactgagtgt ctacacttct atttaccact gtcaggatac
     6181 acttagggcc ttcactaatg acccgagtta ttctggtcat ctgtggaact ggtgacagat
     6241 ggaatacctt aggggaggca gctggtaaca tcacaaaggg ctttgcaggg acaagagtga
     6301 agttgtggat ttgtattttt tgaagctccc aagtgagttg taatgtgaaa ataaagttca
     6361 gcctaatgtg c
//
