LOCUS       NM_001033484            5676 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus IQ motif containing GTPase activating protein 3
            (Iqgap3), mRNA.
ACCESSION   NM_001033484 XM_001001117 XM_892303 XM_900035 XM_900047 XM_900053
            XM_980709 XM_987883 XM_987929 XM_987972 XM_988004 XM_988041
            XM_988104
VERSION     NM_001033484.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5676)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5676)
  AUTHORS   Douchi,D., Yamamura,A., Matsuo,J., Melissa Lim,Y.H.,
            Nuttonmanit,N., Shimura,M., Suda,K., Chen,S., Pang,S., Kohu,K.,
            Abe,T., Shioi,G., Kim,G., Shabbir,A., Srivastava,S., Unno,M.,
            Bok-Yan So,J., Teh,M., Yeoh,K.G., Chuang,L.S.H. and Ito,Y.
  TITLE     Induction of Gastric Cancer by Successive Oncogenic Activation in
            the Corpus
  JOURNAL   Gastroenterology 161 (6), 1907-1923 (2021)
   PUBMED   34391772
REFERENCE   3  (bases 1 to 5676)
  AUTHORS   Matsuo,J., Douchi,D., Myint,K., Mon,N.N., Yamamura,A., Kohu,K.,
            Heng,D.L., Chen,S., Mawan,N.A., Nuttonmanit,N., Li,Y.,
            Srivastava,S., Ho,S.W.T., Lee,N.Y.S., Lee,H.K., Adachi,M.,
            Tamura,A., Chen,J., Yang,H., Teh,M., So,J.B., Yong,W.P., Tan,P.,
            Yeoh,K.G., Chuang,L.S.H., Tsukita,S. and Ito,Y.
  TITLE     Iqgap3-Ras axis drives stem cell proliferation in the stomach
            corpus during homoeostasis and repair
  JOURNAL   Gut 70 (10), 1833-1846 (2021)
   PUBMED   33293280
REFERENCE   4  (bases 1 to 5676)
  AUTHORS   Ray,J.P., Staron,M.M., Shyer,J.A., Ho,P.C., Marshall,H.D.,
            Gray,S.M., Laidlaw,B.J., Araki,K., Ahmed,R., Kaech,S.M. and
            Craft,J.
  TITLE     The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling,
            Differentiation, and Metabolism of T Helper 1 and Follicular B
            Helper T Cells
  JOURNAL   Immunity 43 (4), 690-702 (2015)
   PUBMED   26410627
REFERENCE   5  (bases 1 to 5676)
  AUTHORS   Dixon,M.J., Gray,A., Schenning,M., Agacan,M., Tempel,W., Tong,Y.,
            Nedyalkova,L., Park,H.W., Leslie,N.R., van Aalten,D.M., Downes,C.P.
            and Batty,I.H.
  TITLE     IQGAP proteins reveal an atypical phosphoinositide (aPI) binding
            domain with a pseudo C2 domain fold
  JOURNAL   J Biol Chem 287 (27), 22483-22496 (2012)
   PUBMED   22493426
  REMARK    GeneRIF: Phosphoinositide module is defined by a C-terminal 105-107
            amino acid region of which IQGAP1 and -2, but not IQGAP3, binds
            preferentially to phosphatidylinositol 3,4,5-trisphosphate
            (PtdInsP(3)).
REFERENCE   6  (bases 1 to 5676)
  AUTHORS   Kunimoto,K., Nojima,H., Yamazaki,Y., Yoshikawa,T., Okanoue,T. and
            Tsukita,S.
  TITLE     Involvement of IQGAP3, a regulator of Ras/ERK-related cascade, in
            hepatocyte proliferation in mouse liver regeneration and
            development
  JOURNAL   J Cell Physiol 220 (3), 621-631 (2009)
   PUBMED   19452445
  REMARK    GeneRIF: Report involvement of IQGAP3, a regulator of
            Ras/ERK-related cascade, in hepatocyte proliferation in mouse liver
            regeneration and development.
REFERENCE   7  (bases 1 to 5676)
  AUTHORS   Nojima,H., Adachi,M., Matsui,T., Okawa,K., Tsukita,S. and
            Tsukita,S.
  TITLE     IQGAP3 regulates cell proliferation through the Ras/ERK signalling
            cascade
  JOURNAL   Nat Cell Biol 10 (8), 971-978 (2008)
   PUBMED   18604197
  REMARK    GeneRIF: IQGAP3 is necessary and sufficient for driving cell
            proliferation and ERK acts downstream of IQGAP3
REFERENCE   8  (bases 1 to 5676)
  AUTHORS   Karim,S.A., Johnson,K.J., Griffiths,I.R. and Vouyiouklis,D.A.
  TITLE     A physical map of the genomic region on mouse chromosome 3
            containing the hindshaker (hsh) mutation
  JOURNAL   Genomics 83 (2), 225-230 (2004)
   PUBMED   14706451
REFERENCE   9  (bases 1 to 5676)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC068159.1, CA750580.1 and CX200367.1.
            
            On or before Nov 24, 2006 this sequence version replaced
            XM_892303.2, XM_900053.2, XM_900047.2, XM_900035.2, XM_001001117.1,
            XM_980709.1, XM_988104.1, XM_988041.1, XM_987972.1, XM_988004.1,
            XM_987929.1, XM_987883.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC068159.1, BC151102.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3471              BC068159.1         1-3471
            3472-3869           CA750580.1         283-680
            3870-4686           BC068159.1         3870-4686
            4687-4753           CX200367.1         415-481
            4754-5676           BC068159.1         4753-5675
FEATURES             Location/Qualifiers
     source          1..5676
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 38.78 cM"
     gene            1..5676
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /note="IQ motif containing GTPase activating protein 3"
                     /db_xref="GeneID:404710"
                     /db_xref="MGI:MGI:3028642"
     exon            1..42
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     CDS             6..4904
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /codon_start=1
                     /product="ras GTPase-activating-like protein IQGAP3"
                     /protein_id="NP_001028656.1"
                     /db_xref="CCDS:CCDS38478.1"
                     /db_xref="GeneID:404710"
                     /db_xref="MGI:MGI:3028642"
                     /translation="MEPCAAGRARTAYERLTAEEMDEQRRQNVAYQYLCRLEEAKRWM
                     EVCLKEELPSPVELEESLRNGVLLAKLGHCFAPSVVPLKKIYDVEQLRYQATGLHFRH
                     TDNINFWLSAVAHIGLPSIFLPETTDIYDKKNMPRVIYCIHALSLFLFRLGLAPQIHD
                     LYGKVKFTAEELGNIASELAKYGLQLPAFSKIGGILANEFSADEAAVHAAILAINDAV
                     ERGVVEDTLVTLQNPNALLGNLREPLAAVYQELLALAKMEKAANARNHDDGQEQDIYE
                     SCLTQAEIQGHINLANVQGALEVVDDALERQNPGALLEALHDPVLALQGVRGTFADWY
                     LEQLTSDREQKSQELGLVRLLEKEEIQAGVAVANEKGDEEQTMLQAVWRINKAIRRGV
                     AADTVKELMCPEAQLPRVYPFASAFYQQELALLQKQQQGELGQEELFVAVEMLSAVVL
                     INRALEAGDVCAFWDNLVNPATGLAQVEEENAQRYFDALVKVQQFQGTHRGILSWNDL
                     QAAVSQVNEQVQEETDQVLAISLINEALDQGCPEKTLSALLLPAAGLEDVSLHVAPRY
                     HLLLVAAKRQKARVTGDPGAVLWLEEIRQGVARANEDTSTAQRIALGVAAINQAIKEG
                     KAAQTERVLRNPNVALRGIVPDCAKSYQQALEGAAAKKQCPGDTAFWVQHDMKDGTAY
                     YLHLQTFQGTWEHPSGCHLNTSHLTWEEIQSVITKVTAAHDRQLLWKANVGFVIKLQA
                     RLRGFLVRQKFAESSHVFRTLLPAVIKIQAHWRGYRQRKAYQERLQHFKANLDAIIKI
                     QAWARMWAARRRYLRRLRYFQKNVDSVVKIQAFFRARKARDDYRMLVHARHPPLCVVR
                     KFAHLLNQSQEDFSAESELLKLQEEVVRKIRSNQQLEQDLNLMDIKIGLLVKNRITLQ
                     EVVSHCKKLTKKNKEQLSDMMILDKQKGLKSLSREKRQKLEAYQHLFYLLQTQPIYLA
                     KLIFQMPQNKTTKFMEGVIFSLYNYASNRREAYLLLQLFRTALQEEIKSKVEQPQDVV
                     TGNPTVVRLVVRFYRNGRGQSALQEILGKVIQDVLEDRSVSIHTDPVHIYKSWINQEE
                     AQTGQRSHLPYDVTPEQALSHSEVQRRLDISLRSLLTLTEKFFVAISSSVDHIPYGMR
                     YMAKVLKTTLEKKFPNATERDIYKVVGNLLYYRFLNPAVVAPDAFDIVAMAAGSTLAA
                     PQRHALGAVAQLLQHAAAGQIFSGESRHLRVLNDYLEDLHLKFRKFICRACRVPEPEE
                     RFAIDEYSDMVAVAKPMVYITVGELIGTHRLLLEHQDQLAPGHQDPLHQLLEDLGEPP
                     TISDLIGDNIATDGHVDLSRLEVSLTLTNKFEGLETDADHNSNQSLLLSTKQMLADLI
                     QFHPGESLEEILTSSAPREHEEAHRRLMCWRQACDTQKPEPLRRHHSLMAHSLLSLSE
                     KQQRVLRNLRRLQGLGLVRASDCYQGLVDELAKDICNQRRHRQRRKAEMLRLRTTLQG
                     LDAKTIFYEEQGDYYNQYIQACLDHLAPKPKSSGKGKKQPSLHYTAAQLLEKGVLVEI
                     EDLPVSHFRNVIFDITPGDEAGRFFVNAKFLGVDMEKFQLHYQDLLQLQYEGVAVMKL
                     FNKAKVNVNLLIFLLNKKFLRK"
     exon            43..130
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            131..287
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            288..365
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            366..442
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            443..510
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            511..624
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            625..803
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            804..882
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            883..1046
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1134
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1298
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1456
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            1457..1578
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            1579..1742
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            1743..1833
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            1834..2001
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            2002..2141
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            2142..2312
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            2313..2396
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            2397..2468
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            2469..2538
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            2539..2747
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            2748..2900
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            2901..3064
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            3065..3289
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            3290..3430
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            3431..3515
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            3516..3748
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            3749..3881
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            3882..3984
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            3985..4111
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            4112..4199
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            4200..4412
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            4413..4579
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            4580..4681
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            4682..4790
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     exon            4791..5676
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5652..5657
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /note="hexamer: AATAAA"
     polyA_site      5676
                     /gene="Iqgap3"
                     /gene_synonym="D030034H08"
                     /note="major polyA site"
ORIGIN      
        1 ggaacatgga gccgtgcgcg gcaggccgag ctcggacagc ctatgagcgc ctcacagctg
       61 aggaaatgga tgagcagagg cgacagaatg tcgcctatca gtacctctgc cggctggagg
      121 aagccaagcg ttggatggag gtgtgcttga aggaggagct tccttcccct gtggagctgg
      181 aggagagcct ccggaatgga gtgctactgg ccaagctggg ccactgtttt gcaccctctg
      241 tggtccccct gaagaagatc tacgacgtgg agcagctacg ctaccaggcg actggcttgc
      301 atttccggca cacggacaac atcaactttt ggctctctgc ggtagcccac atcggtctgc
      361 cttcgatctt cctcccagag accacagaca tctatgacaa aaagaacatg cctcgggtga
      421 tctactgcat tcacgctctc agtctcttcc tcttccggct gggattggct ccacagatcc
      481 atgacctgta tgggaaagtg aaattcacag ctgaggaact cggcaacatc gcctctgaac
      541 tggccaaata tggcctccag ttaccggcct tcagcaagat cgggggcatc ctggccaatg
      601 agttttcagc cgatgaggct gcagtccatg cagctattct ggccatcaat gatgccgtgg
      661 agcgaggggt ggtagaggac actctggtca ccttgcagaa tcccaatgct ctcctgggga
      721 atcttcgaga acctctggca gctgtctacc aagagctgct ggccctagcc aagatggaga
      781 aggcggccaa tgccaggaat catgacgatg gtcaggagca ggacatctat gaatcctgcc
      841 tcacccaggc agagatccag ggccacatca acctcgccaa cgtccagggg gcactggaag
      901 ttgttgacga cgctctggag aggcagaacc ctggggcctt gcttgaggcc cttcacgatc
      961 ctgtcctggc cctacaaggg gtgagaggaa cctttgctga ctggtacctg gaacagctga
     1021 cttcagaccg agagcagaaa tcacaggagc tgggcctggt gagacttcta gaaaaggagg
     1081 agatccaggc tggtgtggct gtagccaatg agaaggggga tgaagagcaa actatgctcc
     1141 aggctgtgtg gaggatcaac aaagccatcc ggaggggagt ggctgctgac accgtgaagg
     1201 agctcatgtg ccctgaagcc cagctgcccc gagtctaccc ctttgcctct gctttttacc
     1261 agcaagagct ggctctcctc cagaagcagc aacaggggga gctgggccag gaggagctct
     1321 ttgtggctgt ggagatgctg tcagccgtgg ttctgattaa ccgtgctctg gaagctggag
     1381 atgtctgtgc cttttgggac aatctagtga atcccgcaac tggcctagcc caggtagaag
     1441 aagaaaatgc ccaacgttac tttgatgccc tggtgaaggt tcagcagttt caaggaacac
     1501 atagaggcat cctgagctgg aatgacctgc aggctgctgt gagccaggtc aatgaacagg
     1561 tccaggaaga aactgatcag gtcctcgcca tcagcctcat caatgaggct ctggaccagg
     1621 gctgtcctga aaagactctg tctgccctgc tgcttcctgc agctggcctg gaagatgtca
     1681 gccttcatgt tgcacctcgg taccatctcc tccttgtggc tgctaagagg cagaaagcac
     1741 gggtgacagg agaccctgga gctgtgctgt ggctggagga gatccgccaa ggagtggcca
     1801 gagccaacga ggacacaagc acggctcaga gaatagccct tggtgtggct gctatcaacc
     1861 aggccatcaa ggagggcaag gcagcccaga cagagcgtgt gttgaggaac cccaatgtgg
     1921 ccctccgagg gatagttcct gactgcgcta aaagctacca gcaggccctg gaaggcgcag
     1981 cggcaaagaa gcaatgccct ggggacacag ccttctgggt tcaacatgac atgaaggatg
     2041 gcaccgccta ctaccttcat ctgcagacct ttcaggggac ttgggagcat ccttccggct
     2101 gccacctcaa tacctcccat ctaacctggg aggagattca gtcagtcatc accaaggtca
     2161 ctgctgccca tgaccgccaa ctgctctgga aggccaatgt tggctttgtc atcaagctcc
     2221 aggcccgcct tcgtggcttc cttgttcgcc agaagtttgc tgagtcttcc cacgtcttca
     2281 ggaccttgct tccagccgtc atcaagatcc aggctcactg gcggggttat agacaacgga
     2341 aggcttacca ggagcggctg cagcatttta aagcgaacct ggatgctata atcaagatcc
     2401 aggcctgggc ccgaatgtgg gcagcacgga ggcgatacct caggcgtctg cgatacttcc
     2461 agaagaacgt tgactccgtt gtgaagattc aagcattttt ccgagccagg aaagcccgtg
     2521 atgactacag gatgttagtg cacgcacgcc atcctcccct ctgtgtagtc cgaaaattcg
     2581 ctcacctctt gaaccagagt caggaggact tctcagctga atcggagttg ctaaagctcc
     2641 aagaggaagt ggttaggaag atccgctcta accagcagct ggagcaggac ctcaacctca
     2701 tggacatcaa gattggtctg ctcgtcaaga accgcatcac cctgcaggag gtagtctccc
     2761 actgcaagaa gctgaccaag aagaataagg agcaactgtc ggacatgatg atcctggaca
     2821 aacagaaggg attaaagtca ctgagcagag agaaacggca gaagctagaa gcctaccagc
     2881 acctcttcta cctgctgcag actcagccca tctatttggc caagctgatc tttcagatgc
     2941 cccagaacaa aactaccaag ttcatggaag gtgtgatttt cagtctgtac aactatgcct
     3001 ccaaccgtcg ggaggcctac cttctgctcc agctgttcag gacggcgctc caggaggaaa
     3061 taaagtcaaa ggtggaacag ccccaggatg tggtgacagg caaccccaca gtggtgagac
     3121 tggtggtgag gttctaccgc aatgggcggg gacagagcgc tctgcaggag atccttggca
     3181 aggtcatcca ggatgtgcta gaagacaggt cagtcagcat ccacacagac cctgtccaca
     3241 tctataagag ctggatcaac caggaggagg cccagactgg acagcgcagc catctcccct
     3301 atgacgtcac ccctgagcag gctctgagcc actctgaagt gcagagacga ttagacatct
     3361 ccctgcgcag tctcctcacc ttgactgaga agttctttgt cgccatcagt tcatctgtgg
     3421 accacattcc gtatgggatg aggtatatgg ccaaagtcct gaaaacaacc ttggagaaga
     3481 agttccccaa tgccaccgag agggacatct ataaggtggt tgggaacctc ctgtactacc
     3541 gcttcctgaa cccagctgtg gtcgctcctg atgcctttga cattgtggcc atggcggcag
     3601 gcagcaccct ggccgcccca cagcgccatg cgctgggagc cgtggctcag ctcctacagc
     3661 acgctgctgc tggccagatc ttctctgggg agagccggca ccttcgagtc ctgaatgact
     3721 acctggagga cttgcatctc aagttcagga agttcatctg cagagcctgc cgggtaccag
     3781 agccagagga gcgcttcgcc atcgatgaat actcagacat ggtggctgtg gccaaaccca
     3841 tggtgtacat cactgtaggg gagctcatcg gcacacacag gctcttgctc gaacaccaag
     3901 accagctggc cccaggtcac caagacccac tgcaccagct cctagaagac cttggggagc
     3961 cacccaccat ctctgacctc attggggaca acatagccac agacgggcat gtggacctga
     4021 gcaggctcga agtgtccctg acactcacca acaagtttga agggctggag acagatgctg
     4081 accacaacag caaccaaagt ctgcttctga gcaccaaaca gatgctggcc gacctcatcc
     4141 agttccaccc tggggagtcc ctggaagaga tcctgacctc ctcggctccc agagagcatg
     4201 aagaagccca tcgtcggttg atgtgttggc gccaagcctg tgacacccag aaaccagagc
     4261 cacttcgacg acaccactca ctaatggcac acagtctcct gtcactgtcg gagaagcagc
     4321 aacgcgttct gcggaacctg cgtcggctac agggcctggg gctggtcagg gccagtgact
     4381 gctaccaggg acttgtagac gagctggcca aggacatctg caaccagcgt aggcaccggc
     4441 aacggcggaa ggcagagatg ctgaggctcc ggaccacact gcagggccta gatgcaaaaa
     4501 ccatcttcta tgaggaacag ggtgactact acaaccaata catccaggcc tgccttgacc
     4561 acctggcccc caaacccaag agttctggga aggggaagaa gcagccgtct cttcactaca
     4621 cagccgccca gctcctagaa aagggcgtct tggtggaaat tgaagatctc cctgtttctc
     4681 acttcagaaa cgtcatcttt gacatcactc ctggagacga ggcaggaagg tttttcgtca
     4741 atgccaagtt cctgggtgtg gacatggaga agtttcagct ccactaccag gacctcttgc
     4801 agctgcagta tgagggtgtg gctgtcatga aactctttaa caaagccaaa gtcaacgtca
     4861 atctcctcat cttcctgctc aacaagaagt tccttcggaa gtgacggatg caggcggaac
     4921 tgaggcctct cagctgactg gctgctgcgc ttctccatta cccagctctt ttctccgaag
     4981 accagagctc gggccacaat gcttgaccct cccgcccaag aggaattgtc ctacttggct
     5041 gaagtgggcc atgctccagg tccggccggg tggcttttac cacatccccg ggaaccagga
     5101 gcctgcactc agtcctgcaa agaaccatgg ttttgtgtcg ctactgctct cgtgtggtca
     5161 ccacggtgtc cgccagtcgt cctagcactg cccagcagcc ttatctccct tcctttccac
     5221 gggcttccaa agcccgggcc aggctgtctg cccaactccg cttcataagc catgggtgtc
     5281 gctgtcccct acagcccagg tccctctgtg ctgtgcccct cagccacctc tatcatcctg
     5341 tcctagcctt gacttggtgc agcacttgct gatgtccatg acagctgagt gcacacctca
     5401 aatctccttt ccccacttgt ggtggttctt atgtgggtca ctggggtatt tattctaacc
     5461 tgattgttgt gtggccttaa tcatggtttt aattctcact ttctgaactc agagttcttg
     5521 tcttgccatc ttctcgtcac ctcagagctg acttccaggt ggttctcata gacctgtagg
     5581 ccagccttgg ccatctctgt cctccccaca tctcccatct tcctgcctca ctgccctcta
     5641 gatttcctct taataaaatg ttatttccta tgttaa
//
