LOCUS       NP_001298027            1071 aa            linear   ROD 30-APR-2024
DEFINITION  IQ domain-containing protein H isoform 1 [Mus musculus].
ACCESSION   NP_001298027 XP_006511615
VERSION     NP_001298027.1
DBSOURCE    REFSEQ: accession NM_001311098.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 1071)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 1071)
  AUTHORS   Navarrete-Lopez,P., Lombo,M., Maroto,M., Pericuesta,E.,
            Fernandez-Gonzalez,R., Ramos-Ibeas,P., Parra,M.T., Viera,A.,
            Suja,J.A. and Gutierrez-Adan,A.
  TITLE     An ancient testis-specific IQ motif-containing H gene regulates
            specific transcript isoform expression during spermatogenesis
  JOURNAL   Development 150 (7) (2023)
   PUBMED   36975404
REFERENCE   3  (residues 1 to 1071)
  AUTHORS   Yin,L.L., Li,J.M., Zhou,Z.M. and Sha,J.H.
  TITLE     Identification of a novel testis-specific gene and its potential
            roles in testis development/spermatogenesis
  JOURNAL   Asian J Androl 7 (2), 127-137 (2005)
   PUBMED   15897968
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB610295.1, AK019535.1, AK029502.1 and AC122057.3.
            
            On Jul 24, 2015 this sequence version replaced XP_006511615.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK019535.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1071
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 34.08 cM"
     Protein         1..1071
                     /product="IQ domain-containing protein H isoform 1"
                     /note="IQ domain-containing protein H"
                     /calculated_mol_wt=122474
     Region          262..286
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9D2K4.3)"
     Region          406..433
                     /region_name="IQCD"
                     /note="IQ (isoleucine-glutamine) motif containing D
                     (IQCD); cd23767"
                     /db_xref="CDD:467745"
     CDS             1..1071
                     /gene="Iqch"
                     /gene_synonym="4921504K03Rik"
                     /coded_by="NM_001311098.1:77..3292"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS81021.1"
                     /db_xref="GeneID:78250"
                     /db_xref="MGI:MGI:1925500"
ORIGIN      
        1 maqaqedsdp igsiliqvhe dlhqlkeklv kfsaeetrst ldiqnletai qrtemglkih
       61 idkylgvvnq evlmapvkks lespvtskws iptvidqksf ifpmdsdfwr pqkhrgsllh
      121 glrrakpkiq lttkvmqdpe nkhhraavta sygislphin qrkaqdkvqr likgstisnl
      181 tvlppshrtd phfipipvlq kdaskgvlsm ierglippta ritfqnppik pqalplhsfd
      241 ehrkvpmeas fplalkprpv peeveepshq ieipkgrakr srgplrrkgm kirtpsktrk
      301 spwdyifsvy ngcvdrtapd flafksrfkl iwgsifsfle qiekflkdya iseakikgks
      361 lvsllpefel knkltrndvl avlenpvhiq mllnlpgqry kgqdgkaeaa tkiqatwksy
      421 karssfisyr qkkwasgvia lawllhchrt rlkrivkesr qrhlenfrir aqhlaanwsr
      481 irtsrrtiih ipslgysqyv rkhifdldve qnmqlgrlcd iidanvnviy icshpmtdel
      541 klyyrkllsl qaavktgyyg drtdlqnrfr iitpeavnvf tkhhmclath lmyspkaikr
      601 iknlirgeea yivggilhrd dlavadmlnv pilgsepelv hlysaksgsk rifdnanvpm
      661 ppgiydiyty qqmieqlsql vtdnlgirrw vfkmntefgg ngtafcdips hlqcynwvlk
      721 ernrfghedw kkkwaqesal vkiseelagi laqhvqlvne krfptwrkfl hmfltqggvi
      781 eayppadsvt nltvdmliep dgevrvlsmg dqlhadgpfi ssgttmpqts vdpqvlnslc
      841 lqignickek dvvgyfsidl vtfidpstle qqvwttglnl sysdqlamtq ltlyltnghl
      901 ncslstlevp rftedserer krlsiqaela petsryavms tqlkhdnlsl ifyyvflqmc
      961 kahgigydle drqgtvfily eslkryklgm ltigvdlqgv lmtfarnlfi ihqeisapdm
     1021 qgetnfktti ddietilgvt eenkmifvre kqskeeednl yepveihsei v
//
