LOCUS       NM_178378               4027 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus IQ motif containing G (Iqcg), mRNA.
ACCESSION   NM_178378 XM_148412
VERSION     NM_178378.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4027)
  AUTHORS   Stauber,M., Weidemann,M., Dittrich-Breiholz,O., Lobschat,K.,
            Alten,L., Mai,M., Beckers,A., Kracht,M. and Gossler,A.
  TITLE     Identification of FOXJ1 effectors during ciliogenesis in the foetal
            respiratory epithelium and embryonic left-right organiser of the
            mouse
  JOURNAL   Dev Biol 423 (2), 170-188 (2017)
   PUBMED   27914912
REFERENCE   2  (bases 1 to 4027)
  AUTHORS   Li,R.K., Tan,J.L., Chen,L.T., Feng,J.S., Liang,W.X., Guo,X.J.,
            Liu,P., Chen,Z., Sha,J.H., Wang,Y.F. and Chen,S.J.
  TITLE     Iqcg is essential for sperm flagellum formation in mice
  JOURNAL   PLoS One 9 (5), e98053 (2014)
   PUBMED   24849454
  REMARK    GeneRIF: Iqcg is specifically required for spermiogenesis in
            mammals
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4027)
  AUTHORS   Harris,T.P., Schimenti,K.J., Munroe,R.J. and Schimenti,J.C.
  TITLE     IQ motif-containing G (Iqcg) is required for mouse spermiogenesis
  JOURNAL   G3 (Bethesda) 4 (2), 367-372 (2014)
   PUBMED   24362311
  REMARK    GeneRIF: Loss of Iqcg disrupts spermiogenesis such that tail
            formation either occurs incompletely or breaks apart from the sperm
            heads.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4027)
  AUTHORS   Ward,J.O., Reinholdt,L.G., Hartford,S.A., Wilson,L.A., Munroe,R.J.,
            Schimenti,K.J., Libby,B.J., O'Brien,M., Pendola,J.K., Eppig,J. and
            Schimenti,J.C.
  TITLE     Toward the genetics of mammalian reproduction: induction and
            mapping of gametogenesis mutants in mice
  JOURNAL   Biol Reprod 69 (5), 1615-1625 (2003)
   PUBMED   12855593
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY120455.1, BC049990.1 and AC126023.3.
            
            On Apr 15, 2009 this sequence version replaced NM_178378.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC049990.1, SRR11927938.4354250.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-16                BY120455.1         2-17
            17-1771             BC049990.1         1-1755
            1772-4027           AC126023.3         131793-134048       c
FEATURES             Location/Qualifiers
     source          1..4027
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 23.55 cM"
     gene            1..4027
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /note="IQ motif containing G"
                     /db_xref="GeneID:69707"
                     /db_xref="MGI:MGI:1916957"
     exon            1..36
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /inference="alignment:Splign:2.1.0"
     exon            37..107
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /inference="alignment:Splign:2.1.0"
     CDS             100..1359
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /note="IQ domain-containing protein G"
                     /codon_start=1
                     /product="dynein regulatory complex protein 9"
                     /protein_id="NP_848465.1"
                     /db_xref="CCDS:CCDS37316.1"
                     /db_xref="GeneID:69707"
                     /db_xref="MGI:MGI:1916957"
                     /translation="MDEEEVEVVESPSEVLQPEVTVVVTGEPPEAAEEDLDYEEEEET
                     SPEVIETLSLLDVLRVSAVMEDVIDQLSILGYIIPVQYERRQSLTQKASHEGASMITT
                     TPKKSTSLLTKEKSMMAENKQRGQDFTFKKPTKQTMMTLETLKKIQNDRQYFSDVIAN
                     AMMEMQDSGSFTSLLKALGKERDSKMNFHDVITREEKGRKQIKTLQKQLLDVKRERQM
                     QVQNGNEYIAHLRDQLQEMKAKTNLENLYMKRNAELQISQTQKKCNRAEELLLEEIEK
                     LRMKTEEENRVHTEIEMFLKKQQQKLEEKLEFWMEKFDKDTEAKQNELNALKAAKASD
                     LVHLQDLAKMIREYEQVIIEDRIEKEKTRKKLEQDDLELRSIVKLQAWWRGSVVRKEI
                     GNFKMPKKDKDDSKDSKGKEKEKRRKK"
     exon            108..369
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /inference="alignment:Splign:2.1.0"
     exon            370..551
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /inference="alignment:Splign:2.1.0"
     exon            552..680
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /inference="alignment:Splign:2.1.0"
     exon            681..762
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /inference="alignment:Splign:2.1.0"
     exon            763..924
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /inference="alignment:Splign:2.1.0"
     exon            925..999
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1131
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1233
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /inference="alignment:Splign:2.1.0"
     exon            1234..4027
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1644..1649
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /note="hexamer: ATTAAA"
     polyA_site      1672
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /note="major polyA site"
     regulatory      1713..1718
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /note="hexamer: AATAAA"
     polyA_site      1752
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
     regulatory      3735..3740
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
                     /note="hexamer: ATTAAA"
     polyA_site      3758
                     /gene="Iqcg"
                     /gene_synonym="2400003L07Rik; esgd12d; G1-374-12; repro1;
                     stubby12d"
ORIGIN      
        1 agtttggttc ccgcctccag ctgggctggt agagaggttc cttcattctt gtgaaattat
       61 aaatctagcc cagagggcaa ggaaagaaac tgaggaagaa tggacgagga agaggtggaa
      121 gtcgtggagt ctccttcaga ggttttacaa cctgaggtca ctgtggtggt gacaggagag
      181 cctcctgaag ctgcagaaga agatctagat tacgaagaag aggaagagac ctccccggaa
      241 gtcatagaga cgctgtccct tctagacgtg ctgagggtgt cggccgtcat ggaggacgtc
      301 attgaccagc tctctattct cggctacatc attccggttc agtatgaaag aaggcagagc
      361 ctcacccaga aagccagcca cgaaggagca tctatgatta caaccacacc gaaaaaatct
      421 acttctttgt taactaaaga aaaatccatg atggcagaaa acaaacagag agggcaggac
      481 tttaccttta aaaaacctac aaagcagacc atgatgactc tggagacact gaagaaaatt
      541 cagaatgaca ggcaatattt cagtgatgta attgcaaatg ccatgatgga gatgcaagat
      601 tctggctctt tcaccagtct cctgaaagcc ttgggcaaag aaagagacag caaaatgaat
      661 ttccatgatg tcatcacaag ggaggaaaag ggaagaaaac agataaaaac ccttcaaaaa
      721 cagttacttg atgtcaaaag ggagcgtcaa atgcaagtac agaacgggaa tgaatacatt
      781 gctcacctca gggaccagct acaagagatg aaggcgaaaa ccaacttgga gaatctttat
      841 atgaaaagaa atgctgagct gcagatttcc cagacccaga agaaatgtaa ccgagcagaa
      901 gaactcttgc tggaggagat tgagaaactg aggatgaaaa ctgaagagga gaaccgggtt
      961 cacacggaga tcgaaatgtt tcttaaaaaa cagcagcaga aacttgagga gaagctagag
     1021 ttctggatgg agaaatttga caaagacaca gaagcaaagc agaacgagtt aaatgctctc
     1081 aaggctgcca aggccagtga cctggtacac ctgcaagacc tggcaaagat gatccgggag
     1141 tacgagcagg tcattattga ggaccggata gaaaaggaga agacccggaa gaagctggag
     1201 caggatgacc tggagctgag gagcatcgtg aagctccagg cctggtggcg agggtcagtg
     1261 gtccggaagg aaattggcaa tttcaaaatg cccaagaaag ataaagatga cagcaaagac
     1321 tcgaaaggca aggagaagga gaagaggaga aagaagtaac cagtttctgc tgagccttct
     1381 caggcctcga gacactgggg gtgctgaccc agcgcccacc tcctggctca cagacctagg
     1441 gagttctcac tgtctgatac tctagttttc acaccccagt gagggctatc acatggctgt
     1501 aggacctctt cagacgggac tgtggggagc caagttgagt agctgtgtga gcatccttct
     1561 tctcgctcca gaaagcagct aactggctca tagttaagtc gtaaaaactc ctgacacatc
     1621 tgactctgac tttatgccat atgattaaag tgaaaaacta ttataagcaa aagtgaattc
     1681 tcacctagca tcatgtgcac gcacatgtag ttaataaaca ttggctctgc ctgtcttgca
     1741 gggcgaccat tagtctaggg ttggtggtgt tgggggacag cacataaaac acctcttaca
     1801 taagcagttc cagtgacttt tctggggaca gatagggatg gaagcatctg atacaagatg
     1861 gaaatggcat gtagatacac agtcctccag gggtaaagaa tggggcacgg gttctccaga
     1921 ggctagttta gagatacact tgtcaaagga gacacaacta tgtccatcat ctggatttta
     1981 agacgtaaag aaaccaacca aaccaaccaa ccaaccaacc aaccaaccaa ccaaccagtg
     2041 tatatgtggg cccaggcttg gaaacgtgtg catgccacag tgtgcagggg gtggagtcag
     2101 aggacaggtt ccaagaattg tttccttcta atgtatctct ttgtactatt tgggtctcag
     2161 atatcaaact caagtcattg gacttggcag caagcccctt ttcctgctga gccatttcat
     2221 tggccctcaa ctgtggtttt tttttttccc ctgagagaaa tgttacctta atgtgtctca
     2281 catatttcat gaatataaaa tttaaacttt ttgatgcagg gtctcatgtg gcccaggttg
     2341 gtttcaaatt cactacgtag tctagtggcc ttgaacctca tgttgtgcct cctaagtgct
     2401 agaactacag gggcgagtga ccatacctgg tttatgcagc gttgggaatg gaacttggac
     2461 tccatgcatg ctagtaggca cacttctgac tgtactccag ccccagcctg agtggagcct
     2521 tctcatccac tgcctacgca ggccagcctg ctatctgtac ctctttaaga aagagactgt
     2581 gagcctcaaa ggttcagtga gccagataaa tggcctttcc atgactggtc tctggcaaga
     2641 aaaccatgct ttaggctgga acaatttaaa gtgtttatta catgctactg gagtatattg
     2701 gcttttaatg tccacatata agatgacata caggcaattt aaaataacat acacagtact
     2761 gacatattta tacttagaac ttacacaaat atttacaaac atacaaatat aggacaatgt
     2821 ttacaaaaac ttattaatta catgtttata acacttcaga aataaaatct gctgtaaacc
     2881 atctcactgc aatgaaaaag gcttctaaat aaccaagttt tccttcattt ctacaaccat
     2941 ctaagtactt agttcttaaa agtccatcag actcgtcagc ataccacatt attagtcact
     3001 gctgactaga ggcaaagaaa cagcaggctc cttcattagt tgcaaggatg tatttacaga
     3061 gctgctggat tggaagccac ccactgctct gccttttcta gtctgttcta ggcagatagg
     3121 aaagttcctc tggaaagttc atcagacctg ctcattacag gggaatcctg gtcagagtgc
     3181 ctggcagcct gcagactgct gacataacat ctctgcaggt ggcagggcag agccaggcag
     3241 acacttggct catctacctt accattggca aggtagccat tgctggtcag gggactatga
     3301 catggctaac tttatcttta tttcccgctg gggtctagca aggttaaata tccaaatgag
     3361 ttgtcctttc caatttggaa acctgtaaga agccacaggg cccaacagaa gcactgacct
     3421 gctgtgtgct gactcacact gcgcaactgt atcctaaccc ttcagagttg cattagtttg
     3481 gtaagtgcat taagtaaggt ctcaggaaag ccgcagtgtt aaaatgtcct cctcctcttt
     3541 ctgagggagg gtctcactat ggagccctgg ctgtcctgga actcaatatg tgaataagat
     3601 ctgtctcctc tgtcactcaa aagctgggag taaaagcatg tgccaccctg ctcggtaatg
     3661 tcaactttta ggaactcttg tagccattcc aagtgttgta ttatgtaatg tcttctgggc
     3721 ccattttctg tacaattaaa tatggaattt agaaatgatg ctgaggttta atgctgccta
     3781 gaggaagcaa atctgcggtc cagcagcaca gctggtcata ggcaagctct ggctgccact
     3841 ctgcggtctg ctggtgaacg ggctaggctc tgagctctgg ttctactctt ctgtgaggac
     3901 tacgatgctc taggttagac ttactttttc tcgagagctc tagtcgcctg agttacaggc
     3961 atgagccacc gtgcctggct gctgttacat gctttgaaac ttgaataaaa gtggcagcgt
     4021 tctaatg
//
