LOCUS       NM_028843                633 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus IQ motif containing F1 (Iqcf1), transcript variant 1,
            mRNA.
ACCESSION   NM_028843
VERSION     NM_028843.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 633)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 633)
  AUTHORS   Fang,P., Xu,W., Li,D., Zhao,X., Dai,J., Wang,Z., Yan,X., Qin,M.,
            Zhang,Y., Xu,C., Wang,L. and Qiao,Z.
  TITLE     A novel acrosomal protein, IQCF1, involved in sperm capacitation
            and the acrosome reaction
  JOURNAL   Andrology 3 (2), 332-344 (2015)
   PUBMED   25380116
  REMARK    GeneRIF: a newly identified acrosomal protein, IQCF1, is closely
            related to sperm capacitation and AR; in particular, it is involved
            in tyrosine phosphorylation of sperm proteins through interaction
            with CaM
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC151729.6 and AK006797.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK006797.1, BU936700.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                AC151729.6         205000-205024
            26-633              AK006797.1         2-609
FEATURES             Location/Qualifiers
     source          1..633
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 57.65 cM"
     gene            1..633
                     /gene="Iqcf1"
                     /gene_synonym="1700055J15Rik"
                     /note="IQ motif containing F1"
                     /db_xref="GeneID:74267"
                     /db_xref="MGI:MGI:1921517"
     exon            1..75
                     /gene="Iqcf1"
                     /gene_synonym="1700055J15Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..621
                     /gene="Iqcf1"
                     /gene_synonym="1700055J15Rik"
                     /note="isoform 1 is encoded by transcript variant 1; IQ
                     domain-containing protein F1"
                     /codon_start=1
                     /product="IQ domain-containing protein F1 isoform 1"
                     /protein_id="NP_083119.1"
                     /db_xref="CCDS:CCDS52910.1"
                     /db_xref="GeneID:74267"
                     /db_xref="MGI:MGI:1921517"
                     /translation="MGEEQQKPEELNAPTDDAPQEKQQPADLSSETEKAKSKKKQELS
                     EKDQVVKIQAWWRGTLVRRSLLHAALSAWIIQCWWRLILPKIMEKRRQSMLDTFQQEQ
                     WAVVRLQSWIRMWRIRRRYCRLLKAVRTIQSHWRGHTCSSRGVIKGQYRISTSQMHLE
                     LEVLLGSGPCIVTECIPLPIKQ"
     exon            76..180
                     /gene="Iqcf1"
                     /gene_synonym="1700055J15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            181..633
                     /gene="Iqcf1"
                     /gene_synonym="1700055J15Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttcacatca atgccggagg agcacagacc tgaggggatt tgaaccatct acacccaatc
       61 catgcgtgaa taatgggtga ggaacagcag aagcctgaag aacttaatgc acctactgac
      121 gatgctcctc aggagaagca gcagccagct gatctatcct cagaaacaga gaaggcaaag
      181 tccaagaaaa aacaggagct ttctgaaaag gaccaagttg taaagatcca agcttggtgg
      241 cgcggtacac tggtacgtcg gtcgctgttg cacgcagccc tcagcgcctg gatcattcaa
      301 tgctggtggc ggttaatact gccaaagatt atggagaaga ggcggcagtc catgctggat
      361 accttccaac aggagcagtg ggcagtcgtc aggttgcagt cctggatccg catgtggcgt
      421 atccgcaggc gttactgccg gttgcttaag gctgtccgga ccatccagtc tcactggaga
      481 ggtcatactt gctcttcacg gggtgttatc aagggccaat accgaatttc gaccagccag
      541 atgcatcttg agctggaggt cttgctgggt tcggggcctt gtattgtgac cgaatgtatt
      601 cccctcccaa taaaacagtg aggcggtggt cgt
//
