LOCUS       NM_008389               2330 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus IAP promoted placental gene (Ipp), transcript variant
            1, mRNA.
ACCESSION   NM_008389
VERSION     NM_008389.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2330)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2330)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   3  (bases 1 to 2330)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 2330)
  AUTHORS   VanHouten,J.N., Asch,H.L. and Asch,B.B.
  TITLE     Cloning and characterization of ectopically expressed transcripts
            for the actin-binding protein MIPP in mouse mammary carcinomas
  JOURNAL   Oncogene 20 (38), 5366-5372 (2001)
   PUBMED   11536049
REFERENCE   5  (bases 1 to 2330)
  AUTHORS   VanHouten,J.N., Natoli,F. and Asch,B.B.
  TITLE     Frequent ectopic expression of a placenta-specific gene at high
            levels in BALB/c mouse mammary carcinomas
  JOURNAL   Oncogene 12 (10), 2241-2245 (1996)
   PUBMED   8668351
REFERENCE   6  (bases 1 to 2330)
  AUTHORS   Chang-Yeh,A., Mold,D.E., Brilliant,M.H. and Huang,R.C.
  TITLE     The mouse intracisternal A particle-promoted placental gene
            retrotransposition is mouse-strain-specific
  JOURNAL   Proc Natl Acad Sci U S A 90 (1), 292-296 (1993)
   PUBMED   7678343
REFERENCE   7  (bases 1 to 2330)
  AUTHORS   Chang-Yeh,A., Jabs,E.W., Li,X., Dracopoli,N.C. and Huang,R.C.
  TITLE     The IPP gene is assigned to human chromosome 1p32-1p22
  JOURNAL   Genomics 15 (1), 239-241 (1993)
   PUBMED   8432546
REFERENCE   8  (bases 1 to 2330)
  AUTHORS   Chang-Yeh,A., Mold,D.E. and Huang,R.C.
  TITLE     Identification of a novel murine IAP-promoted placenta-expressed
            gene
  JOURNAL   Nucleic Acids Res 19 (13), 3667-3672 (1991)
   PUBMED   1906605
REFERENCE   9  (bases 1 to 2330)
  AUTHORS   Mold,D.E., Chang-Yeh,A. and Huang,R.C.
  TITLE     Cell lineage-specific expression of the MIPP gene
  JOURNAL   Biochem Biophys Res Commun 177 (3), 1062-1067 (1991)
   PUBMED   1905535
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL669953.7.
            
            On Mar 27, 2023 this sequence version replaced NM_008389.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK131718.1, SRR13422592.308188.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                AL669953.7         61267-61306
            41-382              AL669953.7         64178-64519
            383-814             AL669953.7         68724-69155
            815-970             AL669953.7         74315-74470
            971-1138            AL669953.7         77842-78009
            1139-1276           AL669953.7         83327-83464
            1277-1399           AL669953.7         84069-84191
            1400-1620           AL669953.7         86214-86434
            1621-2330           AL669953.7         91456-92165
FEATURES             Location/Qualifiers
     source          1..2330
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 53.2 cM"
     gene            1..2330
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
                     /note="IAP promoted placental gene"
                     /db_xref="GeneID:16351"
                     /db_xref="MGI:MGI:96581"
     exon            1..40
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
                     /inference="alignment:Splign:2.1.0"
     exon            41..382
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
                     /inference="alignment:Splign:2.1.0"
     exon            383..814
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
                     /inference="alignment:Splign:2.1.0"
     exon            815..970
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1138
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1276
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..1399
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
                     /inference="alignment:Splign:2.1.0"
     exon            1400..1620
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
                     /inference="alignment:Splign:2.1.0"
     exon            1621..2330
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2033..2038
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
                     /note="hexamer: AATAAA"
     regulatory      2046..2051
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
                     /note="hexamer: TATAAA"
     polyA_site      2064
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
                     /note="major polyA site"
     polyA_site      2073
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
     regulatory      2313..2318
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
                     /note="hexamer: AATAAA"
     polyA_site      2330
                     /gene="Ipp"
                     /gene_synonym="D4Jhu8; Mipp"
ORIGIN      
        1 gcagagcacc ggagggcgcc ggcgggaagg gacgcggcgg gacagaagca gataatgggc
       61 aacagtgtct ttcattaatc tgtgatcacc atgtctaagg aggagtgccc caaggctgct
      121 gacaattcat tctcctctga caaacatgcc cagctcatct tggcgcagat gaacaaaatg
      181 agaagtggac agcatttctg tgatgtgcag ctccaggtgg ggaaggaaac cttccaagtc
      241 catcggctgg tcctggccgc cagcagtccg tactttgcag ctttgttcac tggaggaatg
      301 aaagagtctt caaaagatgt tgtacagatt ctaggagttg aagctggaat ctttcagtta
      361 cttctagatt tcatttatac aggagtagtg aacatagctg tgactaatgt ccaggagttg
      421 attgttgcag cagacatgct acagttgact gaagttgtta atctttgctg tgattttctg
      481 aaaggacaaa ttgatccaca gaactgcatt ggactctttc agttctctga gcaaattgcc
      541 tgccatgatc ttttggaatt tacagaaaat tatattcatg tccatttctt ggaggttcat
      601 actggggaag agttcctcgg gcttacaaaa gatcagctga tcaaaatttt acgaagtgaa
      661 gagcttagca ttgaagatga ataccaagtc ttcttagctg caatgcagtg gattcttaaa
      721 gacctgggaa agagaagaaa acatgtggtg gaagtattag atccagttcg attccccttg
      781 ttaccatctc agaggctttt aaagtacata gaaggagtat ctgattttaa tcttcgagtt
      841 gccctgcaaa cacttttgaa agagtactgt gaggtctgca agtctcccaa agagaacaag
      901 ttttgtagtt tcctgcagac atctaaagtt cgacctcgga agaaagcaag aaaatatctg
      961 tatgcagtag gtggctatac gcggttgcag ggtggccgtt ggagtgatag cagagccctc
     1021 agctgcgtag aacgttttga taccttcagc cagtactgga ccactgtatc ttcacttcat
     1081 caggctcggt gtggactcgg agttgcagtt gtaggaggga tggtctatgc tattggagga
     1141 gaaaaggatt cgatgatctt tgactgtact gagtgttatg atccagttac taaacaatgg
     1201 acaactgttg cttcaatgaa tcacccccgc tgtggattgg gagtatgtgt gtgctacggg
     1261 gcaatctatg ctttgggtgg gtgggttgga gctgagatcg gcaacaccat tgagcggttt
     1321 gatcctgatg agaataagtg ggaagtggtg ggcagcatgg cagtgtcacg ctactacttt
     1381 gggtgctgtg agatgcaagg tttaatttat gcagttggag gaatcagcaa tgaggggcta
     1441 gagctccgtt cctttgaggt ttatgatcca ctttccaagc gctggtctcc acttcctcct
     1501 atgggaacca gaagagcgta tcttggggtg gcagcactca atgactgcat ctatgctatt
     1561 ggagggtgga atgagacaca agatgccctt catactgtag aaaagtactc cttcgaagag
     1621 gaaaagtggg ttgaagttgc ttcaatgaaa gttcctagag caggcatgtg tgctgtgaca
     1681 gtcaatggtc ttctgtatgt ctctggaggc cggtcttcta gccatgattt cttggcccca
     1741 ggtactttgg actcagttga agtttacaac cctcattcag atacatggac ggaaattggt
     1801 aatatgatca ctagtcgttg tgaagggggt gttgctgtac tgtgacagag aaggcacaaa
     1861 agcacaagga acatttgaaa atgtaggttc tgaccatttg caaatcaaac atatatttgt
     1921 gatatgatct tctgattctt ttgagtattc catgtattga atagatagat aagtaaagag
     1981 tgatttttct aaaaatttga attaaaatgg atatgtaata tatcttaaaa ttaataaagt
     2041 acacttataa atttgcaaaa cttagcaaca gtacaaatgg tatttatgcc ttacagttta
     2101 ttcagttatc aatagaatcc taattgtaaa aattgtttgc taaagggctg gagatatggc
     2161 tcagaggtta agaacactga ctgctattct agaggtcctg agttcaaatc ccagcaacca
     2221 catttggtga ctcaaaacca tttgtaatgg gatctgatgc ccccttgtga tgtgtctgaa
     2281 gacagttaca ctgtactcat ataaatacaa taaataaatc gttaaaaata
//
