LOCUS       NM_001170800            5561 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Mus musculus interaction protein for cytohesin exchange factors 1
            (Ipcef1), transcript variant 1, mRNA.
ACCESSION   NM_001170800
VERSION     NM_001170800.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5561)
  AUTHORS   Marks,K.E., Flaherty,S., Patterson,K.M., Stratton,M., Martinez,G.J.
            and Reynolds,J.M.
  TITLE     Toll-like receptor 2 induces pathogenicity in Th17 cells and
            reveals a role for IPCEF in regulating Th17 cell migration
  JOURNAL   Cell Rep 35 (13), 109303 (2021)
   PUBMED   34192530
  REMARK    GeneRIF: Toll-like receptor 2 induces pathogenicity in Th17 cells
            and reveals a role for IPCEF in regulating Th17 cell migration.
REFERENCE   2  (bases 1 to 5561)
  AUTHORS   Wu,Y., Wei,F.Y., Kawarada,L., Suzuki,T., Araki,K., Komohara,Y.,
            Fujimura,A., Kaitsuka,T., Takeya,M., Oike,Y., Suzuki,T. and
            Tomizawa,K.
  TITLE     Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is
            Required for Mitochondrial Translation and Is Involved in
            Reversible Infantile Liver Injury
  JOURNAL   PLoS Genet 12 (9), e1006355 (2016)
   PUBMED   27689697
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5561)
  AUTHORS   Ling,K.H., Hewitt,C.A., Beissbarth,T., Hyde,L., Banerjee,K.,
            Cheah,P.S., Cannon,P.Z., Hahn,C.N., Thomas,P.Q., Smyth,G.K.,
            Tan,S.S., Thomas,T. and Scott,H.S.
  TITLE     Molecular networks involved in mouse cerebral corticogenesis and
            spatio-temporal regulation of Sox4 and Sox11 novel antisense
            transcripts revealed by transcriptome profiling
  JOURNAL   Genome Biol 10 (10), R104 (2009)
   PUBMED   19799774
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC155718.4 and AC164171.5.
            
            Transcript Variant: This variant (1) encodes isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660817.296840.1,
                                           SRR9219380.54096.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164132 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-219               AC155718.4         136446-136664
            220-389             AC155718.4         137228-137397
            390-463             AC164171.5         117557-117630       c
            464-535             AC164171.5         116168-116239       c
            536-594             AC164171.5         98599-98657         c
            595-683             AC164171.5         96685-96773         c
            684-1056            AC164171.5         81212-81584         c
            1057-1250           AC164171.5         62068-62261         c
            1251-5561           AC164171.5         47863-52173         c
FEATURES             Location/Qualifiers
     source          1..5561
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 1.85 cM"
     gene            1..5561
                     /gene="Ipcef1"
                     /gene_synonym="A130090K04Rik"
                     /note="interaction protein for cytohesin exchange factors
                     1"
                     /db_xref="GeneID:320495"
                     /db_xref="MGI:MGI:2444159"
     exon            1..219
                     /gene="Ipcef1"
                     /gene_synonym="A130090K04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            220..389
                     /gene="Ipcef1"
                     /gene_synonym="A130090K04Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             231..1451
                     /gene="Ipcef1"
                     /gene_synonym="A130090K04Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     interactor protein for cytohesin exchange factors 1"
                     /codon_start=1
                     /product="interactor protein for cytohesin exchange
                     factors 1 isoform 1"
                     /protein_id="NP_001164271.1"
                     /db_xref="CCDS:CCDS56688.1"
                     /db_xref="GeneID:320495"
                     /db_xref="MGI:MGI:2444159"
                     /translation="MSRRRISCKDLGHADCQGWLYKKKEKGTFLSNKWKKFWVVLKGS
                     SLYWYSNQMAEKADGFVNLSDFTVERASECKKKNAFKINHPQIKAFYFAAENLQEMNV
                     WLNKLGFAVTHQESITKDEECYSESEQEDPEVAVEAPPPPYASTTSSPVAAQWASSSS
                     PKRRETSCSFSSLENTVKAPSQFSSSGSKERQSWHNIVNSSPATEDAGLPLTFAEQVH
                     TLAFSEASNCQAPENNCITSEGGLLNLLSSDDTSSLNNNKDHLTVPDRAAGSRMADRE
                     EIKSSEDDEMEKLYKSLEQASLSPLGDRRPSTKKELRKSFVKRCKNPSINEKLHKIRT
                     LNSTLKCKEHDLAMINQLLDDPKLTARKYREWKVMNTLLIQDIYQQQAPQDPEVTPQE
                     VMNPTSSDCVENSL"
     exon            390..463
                     /gene="Ipcef1"
                     /gene_synonym="A130090K04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            464..535
                     /gene="Ipcef1"
                     /gene_synonym="A130090K04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            536..594
                     /gene="Ipcef1"
                     /gene_synonym="A130090K04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            595..683
                     /gene="Ipcef1"
                     /gene_synonym="A130090K04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            684..1056
                     /gene="Ipcef1"
                     /gene_synonym="A130090K04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1250
                     /gene="Ipcef1"
                     /gene_synonym="A130090K04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1251..5561
                     /gene="Ipcef1"
                     /gene_synonym="A130090K04Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aattagcaca ttttgtgcct cagctggtag cttcccttga gctctgcttg gagaggcttt
       61 ttttcttttt tagaatccac cccgctcata aacactgcca ccccctccct ccctctctct
      121 ttacaaatgt tacaacacaa tcagaaattt tctcttttct ttccttcctg catttccagc
      181 aggttccctt gcgtcagaag cccaggaaga aaactcaagg gtttttcaac atgagtcgga
      241 gaaggatatc ctgtaaagat ctgggccacg ctgactgcca gggttggctg tacaagaaaa
      301 aggaaaaggg aacttttcta agcaacaaat ggaaaaagtt ctgggtggtg ctgaagggct
      361 catcgctgta ttggtatagc aatcaaatgg cagagaaagc agatggattt gtcaaccttt
      421 cagatttcac agtggaaaga gcctctgaat gcaagaaaaa aaatgcattt aagatcaatc
      481 acccacagat caaagccttc tactttgcag cagagaattt gcaggaaatg aatgtgtggt
      541 taaacaaact tggatttgct gtgacccacc aggaatccat cacaaaggat gaagaatgtt
      601 acagtgagag cgagcaggaa gatcctgaag ttgccgtgga ggcaccaccc cctccgtatg
      661 cttccacaac ttcctctcct gtggctgcac agtgggcatc ttcttcttca cctaaacgga
      721 gagaaacatc atgttctttc tcttctctgg aaaatacagt aaaggcaccc agccagtttt
      781 cttcctcggg atctaaagaa cgacagtcct ggcacaacat agttaacagc tcacctgcta
      841 ctgaagatgc ggggcttccc ctcacatttg ctgagcaggt ccacacactt gccttctcag
      901 aagcaagcaa ttgccaggcc ccagaaaaca actgcatcac atcagaaggt ggtttgttga
      961 acttgttgtc tagtgatgac acttcttcac tgaataacaa taaagaccat ctaacagtcc
     1021 cagacagagc tgctggatca agaatggcag acagagaaga aataaaatca tctgaagatg
     1081 atgagatgga aaaattgtac aaatcactgg agcaggctag cctgtctcct cttggggacc
     1141 ggcggccttc aaccaagaag gagctgagaa agtcttttgt gaagcgatgc aaaaacccat
     1201 cgataaacga gaagttgcac aagatcagaa ccctgaacag cacattaaag tgcaaagaac
     1261 acgatttggc tatgatcaac cagctgctgg atgatccaaa gctgacagcc aggaagtaca
     1321 gagagtggaa ggtcatgaac accctgctga tccaggacat ctatcagcag caggcacctc
     1381 aggaccctga agtcacccct caggaagtca tgaatcccac gtcttctgat tgtgtggaaa
     1441 attctctttg agcagatgcc cagatcccac ccccattcct gttactatac cattctacag
     1501 gatgctgcca agggcattca ttctgcttac aaggaaatcc caaacccagt tcctgagaca
     1561 tcatccattc cccgcaagga tgcaactgag gtgaagccag ttttgatgca gtgggagtcc
     1621 tggcgcccag atgttgcctt cctcaatact agaatgaagt gatggagttc atctgagcag
     1681 gcatatcgtc tgtgcttcta ctgggagctg gctggaataa taggctttag gtgggatgtg
     1741 aaatgggtga aacccctctt tttgttttca agagaattac aacctgccat agacaaaagg
     1801 ctcaatttta ccagggataa taattcatgt tattttgttt tgcaaaagaa gcatgaagaa
     1861 ctccctttgg tgggcagcca agttctgcaa aacgttgtga gtggaggaat ttcttcctta
     1921 ttagctactg gaactggacg catgttggca tttgtggaac acaaggctct tcttaatgtt
     1981 gatgttctat ttgctgagca cttatttgca gagtagagca tggtgggggc agagaatgga
     2041 tagcccaagg aggaggcatt tttcctgttc tactcagagg tcagcttcat aagttcatgc
     2101 tttacgtagg gcaggggatg tgattaatat gcctcttcct cacaatgtct aggagacaaa
     2161 ctatcacatg acctttggag atgtcgttcc cccccacccc cagcttctct gaacagtggt
     2221 aggatattaa tacccactgt aaggaatgtt atattaagtt tacccctgcc tgtggtgcct
     2281 agagccagca tgaattcgtg tccagttttc ctgggatcca aattctcaag gttatttctg
     2341 agttgttctt aacttggaga agtacccgga ccagcaaaat gggatcattt tatttttgta
     2401 tgtttatgtg tcaaatggtg tgagatctga acagtgatct atgtttctta tttaaatata
     2461 tttatagaaa tgcaaattat agtgttctaa aagaaagtgt actattatgt gttgatatat
     2521 agactataca tatatatgtg tgtgtgtata tatatatata tatatatgtc tagaagcata
     2581 tcatttttgc ttgagaaaaa taggtatagt agtgacttac tggtattgta ttgcactatg
     2641 atatataaag aatgctcagg aaatctcgag agaaaaccac gggagcatgt attaataatt
     2701 actaattttc tgaatgcttt ctttccatta caaccccacc ctcagctcca gagatcttac
     2761 atttcaatgc ctgttacaca tcattttctt aactagctcc ttaggttagc tcttctattc
     2821 acaaaggtta agctttatga tatttagttg ccatgagttg tagacccaaa gaaacacatc
     2881 tcacaaacta ttgagccaaa taaaatataa acaatatgat tcctaattat atactaataa
     2941 aaattaaagt ttgtcattaa agagatctca aggaaaaaca atatattaat cataatgaca
     3001 acttctaaat cataacctta attcactgag gacctatgtg tgtctcacgt gccctttgaa
     3061 aattgttgac gtatatattc atatcataac atcccaggtg gctcggcaaa ctcaaataga
     3121 aatagccacc tgatctatat ctataaggtg aatagaaaga attgtttatt atttccctgt
     3181 acttcaccaa gacttttttt gtacactgaa atgaaaacca gtccttgcct taggagggaa
     3241 aagtaaagaa gcagcaaaaa gagaagcaga gagaagcaga gagaggcaga gagaagcaga
     3301 aagaagcaga gagaagcaga gagaagcaga gagagagaag cagactcatc aagtggcgag
     3361 acgaagcctg gggatgagct gagaggccct gcagggccct ccatggatcc atgcagttgg
     3421 agatgctaat gcctatcagg actgattcca tttcctcctg tggctagtag ctgttcagag
     3481 ggcaatgttt tggggttcac agtgaaagga agcattgggg ggaggcaaat tagcattgga
     3541 acaaccttag cctgggagaa aatatccact catgtctttt attagcaact ccactttaca
     3601 gacctccatc ctcccccaag tggaagcccc aaacactttt tatgagggct gattgctata
     3661 tttaaatgtt ttacgttggc tttccactca taggtattta actgaccttt gaatgtaaac
     3721 tcctttagga acattcagat ctaaaggcaa agttggttcg tgagattgct tgagcaagtc
     3781 atagggttaa ttttccaggc aacttcaaga aagtcagagc agacatttct gctttggtgg
     3841 aaccagcctg ctgaatgttc ccaagtcagt ctcagccgtg tcctgacctc ctgggcacaa
     3901 accaaccact ctctgttccc cagttctgta aattaatact tcttcactct gggctaagtt
     3961 tagtcacagc gtaggggtgc ttctgtgggt acccagcctc agctgtgatc ctaagagtag
     4021 ggtgaggaca gacgaggtga gcaggagagt gagtgacact tctgggtgag gacagagaga
     4081 gcgacacttc tagagaccct cagtgaagag aaaccatgag gagctatccc ttggcctcaa
     4141 gtctcttctc tggttcaaga gatttgggaa ctatagatct ctcctagtta atggctggga
     4201 aatggactat aggtagtgtg agcccagggg agactcttga ctgtgcctct ggaatgtacc
     4261 agagcaccca tctcaggaca ctggtggtgg atctttgagc acgaatcttt tagaacccat
     4321 ggcactggtt aaggatgagg cttctctggg gacttttggg gaggcagggc tgaaggagga
     4381 ctctttcttt ctgatctgaa gacccagatg agagcctggc agaggaccct cactagttga
     4441 gaagttgcta acacacatat gtcgcacgtt tttctgttgt ttgcaagatg tctgtcattt
     4501 ataagagttc ttagctttcc ctatcgcttt aatctgaggt taaattcaga gtcccagaaa
     4561 gatgctggag cgaacagttg caggattcca acaggccaag aaagaggtca ggtttggagt
     4621 catattttca gtgtgaaccc atgccttata tttgcatagc tctttgaagt ttgctaactg
     4681 tatgttccaa acccccttcc ctgcgtccta ccaccccata ggctaatcgg gatgattgtg
     4741 aactatgggt gtaatgaaat gcctggctca aagccccaag tggtacagcc ggaatctgag
     4801 tttgaatttc aggtctgtca gcccctctgc agaggaggaa tgcttgtctc cgcttagcct
     4861 gctgggggat caaatggtct gacttggccc ctgtgtctat tactctgggt tctgcacacc
     4921 tggctcctgc ggcttctgct gaacccccag aggcactgct gtgagcagtg tctcccgaaa
     4981 ggtcccgctg ccttgccact gggttttctg agaactggag cttggcctga ttgttgtttc
     5041 ttttagtccg ttctataaaa cacactatgt tagcactgtg aggactttaa agctaaagga
     5101 tacaagtctt ttaaagagct ggaaaatgct catttttcta atttttcctt ttgagatgcg
     5161 aactgtcctg tcaggtatca gagacttagg gattagaaat gagccacgga tttgtgatga
     5221 ggctcattcc ctcagggagg gttcagacca catagtcaca cagagggaac aaaggaaaag
     5281 aaaaatagtt ttcagtcttt tgaggagagg tactctgccg atgtaagcca tatttaactt
     5341 tacggacaca ggctgcttgt aaaaagagaa agacaatatt ttggaacagc gatacaaatg
     5401 atctaggtac aaagagtgac tgttcaaatg tcacattata ttgaagcggt actcagccca
     5461 aatgcaggtt tagaatgtag ttctgcttcc cactaacaga ataggataca caaagaagat
     5521 ttccaatctc ttttccatca aacatttctg tatacttacc c
//
