LOCUS       NM_176843               3294 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus integrator complex subunit 5 (Ints5), mRNA.
ACCESSION   NM_176843
VERSION     NM_176843.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3294)
  AUTHORS   Shimogori,T., Lee,D.A., Miranda-Angulo,A., Yang,Y., Wang,H.,
            Jiang,L., Yoshida,A.C., Kataoka,A., Mashiko,H., Avetisyan,M.,
            Qi,L., Qian,J. and Blackshaw,S.
  TITLE     A genomic atlas of mouse hypothalamic development
  JOURNAL   Nat Neurosci 13 (6), 767-775 (2010)
   PUBMED   20436479
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY152900.1, AC129217.3, AK168795.1 and BY546950.1.
            
            On Dec 10, 2009 this sequence version replaced NM_176843.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC039214.1, AK168795.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                BY152900.1         3-20
            19-28               AC129217.3         125804-125813
            29-3285             AK168795.1         2-3258
            3286-3294           BY546950.1         357-365
FEATURES             Location/Qualifiers
     source          1..3294
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 5.95 cM"
     gene            1..3294
                     /gene="Ints5"
                     /gene_synonym="1110055N21Rik; mKIAA1698"
                     /note="integrator complex subunit 5"
                     /db_xref="GeneID:109077"
                     /db_xref="MGI:MGI:1923578"
     exon            1..162
                     /gene="Ints5"
                     /gene_synonym="1110055N21Rik; mKIAA1698"
                     /inference="alignment:Splign:2.1.0"
     CDS             83..3139
                     /gene="Ints5"
                     /gene_synonym="1110055N21Rik; mKIAA1698"
                     /note="int5"
                     /codon_start=1
                     /product="integrator complex subunit 5"
                     /protein_id="NP_789813.1"
                     /db_xref="CCDS:CCDS29556.1"
                     /db_xref="GeneID:109077"
                     /db_xref="MGI:MGI:1923578"
                     /translation="MSALCDPPGAPGPPGPAPATHGPAPLSAQELSQEIKAFLTGVDP
                     ILGHQLSAREHARCGLLLLRSLPPARAAVLDHLRGVFDESVRAHLAALEESPVAGPPH
                     LRPPPPSHVPTGGPGLEDVVHEVQQVLCEFIRANPKAWAPVISAWSIDLMGQLSSTYS
                     GQHQRVPHATGSLNELLQLWMGCRATRTLMDIYVQCLSALIGSCPDACVDALLDTSVQ
                     HSPHFDWVVAHIGSSFPGTIISRVLSCGLKDFCVHSGAGGGASACGNSSQPPSTDPFP
                     GSPAIPGEKRVPKIASVVGILGHLASRHGDSIRRELLRMFHDSLAGGSGGRNGEPSLQ
                     ATVPFLLQLAVMSPALLGTVSGELVDCLKPPAVLSQLQQHLQGFPREELDNMLNLAVH
                     LVSQASGTGAYRLLQFLVDTAMPASVITTQGLAVPDTVREACDRLIQLLLLHLQKLVH
                     HRGGSPGEGVLGPPPPPRPVPFLDALRNHVGELCGETLRLERKRFLWQHQLLGLLSVY
                     TRPSCGPEALGHLLSRARSPEELSLATQLYAGLVVSLSGLLPLAFRSCLARVHAGTLQ
                     PPFTARFLRNLALLVGWEQQGGEGPSALGARFGESASAHLADLAPLLLHPEEEVAEAA
                     ASLLAICPFPSEALSPSQLLGLVRAGVHHFFSSLRLHGPPGVASASQLLTRLSQTSPA
                     GLKAVLQLLVEGALHRGNTELFGGEMDGDNETLSIVSTPLASASLLDINRRHTAAVPG
                     PGGIWSVFHAGVIGRGLKPPKIVQSRNHQEVIYNTQSLVSLLVHCCSASGNSEREGCW
                     GAPTLSPEAAKAVAVTLVESVCPDAAGAELAWPPEDHARATVERDLRIGRRFREQPLL
                     FELLKLVAAAPPALCYCSVLLRGLLAALLSHWEASRHPDTTHSPWHLEASCILVAVMA
                     EGSLLPPALGNMHEVFSQLAPFEVRLLLLSVWGFLREHGPLPQKFIFQSERGRFIRDF
                     AREGGAEGGPHLSVLHSVLHRNIDRLGLFSGRFQAPPPSTLLRQGT"
     exon            163..3294
                     /gene="Ints5"
                     /gene_synonym="1110055N21Rik; mKIAA1698"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3267..3272
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ints5"
                     /gene_synonym="1110055N21Rik; mKIAA1698"
                     /note="hexamer: AATAAA"
     polyA_site      3286
                     /gene="Ints5"
                     /gene_synonym="1110055N21Rik; mKIAA1698"
                     /note="major polyA site"
ORIGIN      
        1 gtttctgtcg cgtttccagt cagcacgcat gcgtcgcctg tgctccgccg ctcccgcctc
       61 aggctccggg tagggctccg ggatgtccgc gttgtgcgac cctcccgggg ccccagggcc
      121 acccgggcct gcccccgcca cccacggtcc cgcgcctctc agtgctcagg agctgtccca
      181 agaaatcaag gcttttttga ccggtgtaga ccctattctg ggccaccagc tctcagctcg
      241 tgaacatgct cgatgtggtc ttctcttgct ccgttctttg ccacctgctc gggctgctgt
      301 gttggaccac ttgagaggtg tttttgatga gagtgtccgg gcccacctag ctgccctaga
      361 agaaagtcct gtggctggtc cacctcacct ccgtccacct ccaccatccc atgtccctac
      421 tggtggacct ggcttagagg atgtggtgca tgaagtgcag caggtgctgt gtgagtttat
      481 ccgggccaac ccaaaggcct gggcacccgt gattagtgca tggtccattg acctcatggg
      541 acaactgagc agcacatatt caggtcagca tcagcgtgtt ccccatgcca ctggctctct
      601 caatgaactg ctgcagctgt ggatgggctg cagggccacc cgcacattaa tggacatcta
      661 tgtgcagtgc ctctcggccc tcattggtag ctgcccagat gcatgtgtgg atgccttgct
      721 agacacttct gtccagcatt ccccacactt tgactgggtt gtggcccata ttggctcttc
      781 ttttcctggc accatcatct cccgagtcct atcttgtggc cttaaggact tctgtgtcca
      841 tagtggggct ggaggaggag ctagtgcttg tggaaactct tctcaacccc cctctacaga
      901 ccccttccct ggatctcctg ccatccctgg ggaaaaacgg gtacccaaga ttgcctcagt
      961 tgtaggcatc ctagggcacc tggcttcccg ccatggagac agcatccgac gggaactgtt
     1021 gcgcatgttt catgatagtt tggcaggggg ttctgggggc cggaatggag agccctctct
     1081 tcaggccaca gttcccttcc tactgcagct ggcagtcatg tcaccagctt tgctcggcac
     1141 agtatctgga gaacttgtgg actgcctcaa gcccccagca gtgctaagcc agctgcaaca
     1201 acacctgcag gggttcccca gagaagagct agacaacatg ctaaacctgg ctgtgcatct
     1261 agtgagccag gcctctggga ctggtgccta ccgcctgctg cagttcttag tagacacagc
     1321 tatgcctgct tcagttatta ctacccaggg cctggctgtg ccagacaccg tgagagaggc
     1381 ctgtgaccgg ctgatccagc tgctattgct acatctacaa aaactagttc atcatcgggg
     1441 agggtctcct ggagaagggg tgctgggccc acccccacct cctcgtccag tgccctttct
     1501 tgatgcatta cgaaaccatg ttggagaact gtgtggagag acattacggc tagaacggaa
     1561 gcgcttcctc tggcaacacc agctcctggg cctactgtct gtctatacac gacctagctg
     1621 tggacctgag gccttgggtc atctactgag cagagccaga agccctgaag agttgagttt
     1681 ggcaacccag ctatatgcag ggctagtggt cagtctctct ggccttcttc ccctggcctt
     1741 ccgaagctgc ctggctcgag tgcatgcagg gactttacag cctcccttca cagcccggtt
     1801 tcttcgaaat ttggccttgt tggtggggtg ggagcagcag ggtggtgagg gcccttcagc
     1861 cttaggggcc cggtttgggg agtctgcctc agctcacctg gctgatctgg ctcctctcct
     1921 actacaccca gaggaggaag tagctgaagc tgctgcctcc ctccttgcaa tatgtccctt
     1981 tccttctgaa gccctgtccc cttcccaact attgggacta gtgagagctg gagtacacca
     2041 cttcttctct tctctaaggc tgcatggccc tcctggtgtg gcttcagcct ctcagcttct
     2101 tacccgcctt tctcagactt ccccagctgg gctcaaggct gtcctacagc tgcttgtaga
     2161 gggagcctta catcggggca acacagaact atttggaggg gaaatggatg gagacaatga
     2221 gaccctctca attgtctcaa cccctttggc ttctgcctca ttgttggaca ttaaccggag
     2281 gcatactgca gcagtgccgg gtcctggagg gatctggtca gttttccatg ctggagttat
     2341 cggccgtggc ttaaagccac ctaaaattgt tcaatctcga aaccatcaag aagtgatcta
     2401 taacacccag agcctcgtta gcctcctagt gcactgctgc agcgcatcag ggaacagcga
     2461 gcgtgagggt tgctgggggg ctcccaccct gagcccagag gcagccaaag cagttgcggt
     2521 gaccttagtg gagagcgtgt gtcctgatgc agctggtgct gagctggcct ggcccccaga
     2581 ggatcatgca cgagccaccg tggagcggga tctccgaatt ggtaggcgct tccgggaaca
     2641 acctctgctg tttgagcttt tgaagctggt agcagctgct cccccagccc tgtgctactg
     2701 ctccgtgctg ctgcgggggc tgctggctgc cctcttgagc cattgggaag cctctcgaca
     2761 ccctgataca acccactccc cctggcatct ggaggcatcc tgtatcctgg tggctgtcat
     2821 ggctgaggga agcctcttgc caccagccct gggtaatatg cacgaggtat ttagccaact
     2881 ggcacctttt gaagtgcgtc tgttgctgct tagtgtctgg ggttttcttc gggagcatgg
     2941 gcccttgccc cagaagttca tcttccagtc tgaacgtggc cgcttcatcc gggactttgc
     3001 cagggagggt ggagctgaag gaggaccaca tctgtctgtg ctgcacagtg tcctccaccg
     3061 caacatcgat cgcctggggc tcttctctgg ccgctttcaa gcacctccgc catccactct
     3121 gcttcggcag gggacttgac cttttctcta caagttgtgc gaggttaaac tgagagaaga
     3181 gcctaaggtg ctacagaagg gtggatgctt ctaagtccgt acgtaatgag tggtgtcact
     3241 tttttcaaac cccaccattt tttctaaata aaatttgccg agttgagaca aaca
//
