LOCUS       NM_027421               5950 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus integrator complex subunit 2 (Ints2), transcript
            variant 2, mRNA.
ACCESSION   NM_027421
VERSION     NM_027421.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5950)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5950)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5950)
  AUTHORS   Alvarez-Dominguez,J.R., Zhang,X. and Hu,W.
  TITLE     Widespread and dynamic translational control of red blood cell
            development
  JOURNAL   Blood 129 (5), 619-629 (2017)
   PUBMED   27899360
REFERENCE   4  (bases 1 to 5950)
  AUTHORS   Tkatchenko,T.V., Moreno-Rodriguez,R.A., Conway,S.J.,
            Molkentin,J.D., Markwald,R.R. and Tkatchenko,A.V.
  TITLE     Lack of periostin leads to suppression of Notch1 signaling and
            calcific aortic valve disease
  JOURNAL   Physiol Genomics 39 (3), 160-168 (2009)
   PUBMED   19723774
REFERENCE   5  (bases 1 to 5950)
  AUTHORS   Baillat,D., Hakimi,M.A., Naar,A.M., Shilatifard,A., Cooch,N. and
            Shiekhattar,R.
  TITLE     Integrator, a multiprotein mediator of small nuclear RNA
            processing, associates with the C-terminal repeat of RNA polymerase
            II
  JOURNAL   Cell 123 (2), 265-276 (2005)
   PUBMED   16239144
  REMARK    GeneRIF: characterization of the human Integrator complex
REFERENCE   6  (bases 1 to 5950)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Kitamura,H., Nakagawa,T., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of FLJ
            genes: the complete nucleotide sequences of 110 mouse
            FLJ-homologous cDnas identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (2), 127-135 (2004)
   PUBMED   15449545
REFERENCE   7  (bases 1 to 5950)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 5950)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL592065.7, CF166557.1, AK129323.1, BC059056.1 and AK164097.1.
            
            On May 9, 2018 this sequence version replaced NM_027421.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK129323.1, BC050081.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AL592065.7         57442-57467
            27-44               CF166557.1         8-25
            45-988              AK129323.1         1-944
            989-4543            BC059056.1         815-4369
            4544-5944           AK164097.1         637-2037
            5945-5950           AL592065.7         104350-104355
FEATURES             Location/Qualifiers
     source          1..5950
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 51.71 cM"
     gene            1..5950
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /note="integrator complex subunit 2"
                     /db_xref="GeneID:70422"
                     /db_xref="MGI:MGI:1917672"
     exon            1..391
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            392..698
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     CDS             403..3999
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /note="isoform 2 is encoded by transcript variant 2; int2"
                     /codon_start=1
                     /product="integrator complex subunit 2 isoform 2"
                     /protein_id="NP_081697.2"
                     /db_xref="CCDS:CCDS25198.1"
                     /db_xref="GeneID:70422"
                     /db_xref="MGI:MGI:1917672"
                     /translation="MTPEGTGLQFVSPFAFEAMQKVDVVRLASLSDPELRLLLPCLVR
                     MALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKL
                     GGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSECNGEFFFKSSEL
                     FESAVYLEEAADVLCILQAELPSLLPIVDVAEALLRVRNGAWFLCLLVANVPDSFNEV
                     CRGLIKNGERQDEESLGGRRRTDALRFLCRMNPSQALKVRGMVVEECHLPGLGVALTL
                     DHTKTEACEDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRKRETSGSVLWQMRR
                     QLLLELMGILPTVRSTRIVEEADVEMEPTVSVYSGLKEEHVVKASALLRLYCALMGIA
                     GLKPTEEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVLWLS
                     WMIKEEAYFESTSGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLS
                     RMKTIFTQEIFTEQVVTAHAVRVPVTSNLSANITGFLPIHCIYQLLRSRSFTKHKVSI
                     KDWIYRQLCETSTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNLFQEV
                     IGGDSVRLTQRFSITAQLLVLYYILSYEEALLANTKTLASMQRKPKSYSSSLMDQIPI
                     KFLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVDDWICEEEITGTDALLRRMLLTS
                     NAKTHSPKQLQEAFSAVPVSHTQVMQIMEHLTLLSASELIPYAEVLTSNMNQLLNSGV
                     PRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSIKFIRQQKYTQNDLMIDPLIVLRC
                     DRRVHRCPPLMDVTLHMLNGYLLASKAYLSAHLKETAEQDRPSPNNTVGLVGQTDAPE
                     VTREELKNALLAAQDSAAVQILLEICLPTEEEKAKGANSDISLRNTQGVTTISTPSKE
                     TEEGEDNLLCNLREVQCLICCLLHQMYIADPNIAKLVHFQGYPCELLPLTVAGIPSMH
                     ICLDFIPELIAQPELEKQIFAIQLLSHLCIQYALPKSLSVARLAVNVMGTLLTVLTQA
                     KRYSFFMPTLPSLVSFCRAFPPLYEDIMSLLIQIGQVCASDVATQTRDIDPIITRLQQ
                     IKEKPSGWSQICKDPSYKNGSRDTGSMDPDVQLCHCIESTIIEIINMSVSGI"
     exon            699..837
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            838..940
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1054
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1185
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1359
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1586
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            1587..1712
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            1713..1784
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            1785..1899
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            1900..1968
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            1969..2103
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            2104..2280
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            2281..2389
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            2390..2494
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            2495..2659
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            2660..2861
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            2862..2987
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            2988..3186
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            3187..3438
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            3439..3546
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            3547..3652
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            3653..3829
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     exon            3830..5950
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5924..5929
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /note="hexamer: TATAAA"
     polyA_site      5950
                     /gene="Ints2"
                     /gene_synonym="2810417D08Rik; mKIAA1287"
                     /note="major polyA site"
ORIGIN      
        1 gcttttctta tcgccgccga cgtcttctca gtgctgtacg gtggccggcg cgtgccagaa
       61 gcttgggatg aatggaggtg cagggtgcag gttgaactaa gtctctgctt tcccctctct
      121 cctggttgct tctccctttt ttttcccttt cctttttact tttttttttt tttttgcagt
      181 gtccccattc tgattctcgc tctgtcgacg gcactgttgg tgccagcgtc agagttcttg
      241 gtgcctgagt cgactccggg cattgccggg gtttggggat ctggataatc acctaggccc
      301 aacttcggac cgcgctctcc atttctgcct cgtctggctc tcggaggcgg aatccgagtg
      361 ggtcccttga ggctggaggg ttgatcttaa ggatcgagag cgatgacgcc cgagggtaca
      421 ggcctgcagt ttgtcagccc ttttgctttt gaagctatgc agaaggtgga tgttgtccgc
      481 ctggcgtcct taagtgatcc ggaattaaga ctcctcttgc cctgcctggt gaggatggca
      541 ctttgtgctc ctgctgacca gagccaaagt tgggcacagg ataagaaact tatacttcgc
      601 ctcctgtctg gagtggaagc tgtcaactcc attgttgcac tgttgtctgt ggacttccac
      661 gctctagaac aagatgccag caaagaacag cagcttaggc ataaacttgg aggaggcagt
      721 ggagagagca tcctggtatc acagcttcag catgggctga cactagagtt tgaacacagt
      781 gattcccctc gtcgattgcg gcttgtgctg agtgaattgt tggcaattat gaacaaggtg
      841 tcagagtgca atggagagtt ctttttcaag tcttctgagc tctttgagag tgcagtgtac
      901 ttggaggaag ctgcagatgt cctttgtatc ttacaagcag agctcccttc cctgcttcct
      961 atagtggacg tcgcggaagc cttgctgcgt gttagaaatg gagcctggtt cttgtgtctc
     1021 ctggtagcca atgttcctga tagttttaac gaagtttgta ggggcctgat caaaaacgga
     1081 gaacggcagg atgaagaaag tctcggaggg aggcgcagga cagacgccct acgcttccta
     1141 tgcagaatga atccttctca ggccctgaag gtccggggca tggtggtgga agaatgtcac
     1201 ttgccaggcc ttggagtagc tttgacattg gatcatacta aaaccgaagc ttgtgaggat
     1261 ggagtgagcg acttggtttg ctttgttagt ggtttgcttc ttggaacaaa tgcaaaagtc
     1321 aggacttggt ttggaacctt cattcgaaat ggacaacaga gaaaacggga gaccagtggt
     1381 tccgtgcttt ggcagatgag aaggcagctg cttctggagt tgatgggcat tcttcctaca
     1441 gtgaggagta cccgtattgt ggaggaagcc gatgtggaga tggaacctac cgtgtcggtg
     1501 tactcggggc tgaaggaaga gcacgtcgtg aaagccagtg cactcttacg tctgtactgt
     1561 gccttgatgg gaattgctgg actcaaacca actgaagaag aagctgagca gttgctgcag
     1621 ctgatgacca gccgacctcc tgccacgccg gccggggttc gctttgtttc cctctccttc
     1681 tgtatgctgc tggccttctc cacactcgtc agcacgccgg agcaggagca gctgatggtg
     1741 ctgtggctca gctggatgat caaggaagag gcgtactttg agagtacatc aggtgtctct
     1801 gcttcttttg gggagatgtt gctattggtg gccatgtatt tccatagcaa ccagcttagt
     1861 gctatcattg acttagtctg ctccactttg gggatgaaga ttgtgattaa gccaagctcc
     1921 ttaagcagga tgaagaccat cttcacacag gagatcttta cagagcaggt tgtcacagcc
     1981 catgcagttc gagttcctgt caccagcaac ttgagtgcca acattactgg gtttttgccc
     2041 attcattgta tttaccaact tctcaggagt cgatcgttta ccaagcacaa agtgtcaata
     2101 aaagactgga tttacagaca gctatgtgaa acttccactc cactccaccc tcagctcctt
     2161 cctctgattg atgtgtacat aaactccata ctcactcctg cgtctaagtc taaccctgaa
     2221 gccacgaacc agccggtcac tgagcaggag atcctgaacc ttttccagga ggtcatcggg
     2281 ggagacagcg tccgccttac ccagcgcttc agtatcacag cgcagcttct ggtgctctac
     2341 tatatcctgt cttacgagga agctctcctg gcgaacacaa agacgctagc ttccatgcag
     2401 aggaaaccca aatcatattc ttcttcttta atggaccaaa ttcctatcaa gtttcttatt
     2461 cggcaggctc aaggactgca gcaggagttg ggagggctgc attcagcttt actacgtctt
     2521 ctagcaacta attatccaca tctgtgtatt gtggatgact ggatctgtga ggaggagatc
     2581 acagggactg atgcgctgtt aaggcgaatg ctcctgacaa gtaatgccaa aacccactct
     2641 ccgaaacagc tgcaggaagc attttcagct gtccctgtaa gtcacacaca agtgatgcag
     2701 attatggaac acttgactct actttctgcc agtgaactta ttccatatgc agaagtacta
     2761 acgtccaata tgaaccagct gctgaattct ggggttccac ggagaattct tcaaactgtc
     2821 aacaagttat ggatggttct taatactgtg atgccaagaa ggctgtgggt aatgacggtt
     2881 aatgcactcc aaccttccat aaagtttata cgacaacaaa aatataccca gaatgatttg
     2941 atgatagatc ctctcattgt cttgaggtgt gaccgacggg ttcacaggtg tcccccacta
     3001 atggatgtta ctttacacat gctcaatggg tacctccttg cctctaaagc ttaccttagt
     3061 gcccatctaa aggaaacggc agagcaagat agaccttccc cgaataatac agtaggcttg
     3121 gttggacaga ctgatgcccc agaagtgacc agagaagaac tgaaaaacgc attactggct
     3181 gctcaggaca gtgctgctgt ccagattctc ttagaaattt gcttgccgac tgaagaggaa
     3241 aaggcaaaag gtgccaattc agacatctcc ctcaggaata ctcaaggtgt caccaccatc
     3301 agcactccaa gtaaagaaac agaagaagga gaagacaatt tgctctgtaa ccttcgggaa
     3361 gttcagtgcc ttatctgttg cctgttacac caaatgtaca ttgcagatcc caacattgct
     3421 aaacttgttc actttcaggg ttatccatgt gaacttctgc ctctgacagt cgcagggatc
     3481 ccgtctatgc acatctgttt ggatttcata ccggagctta ttgcccagcc agaacttgaa
     3541 aaacagatat ttgctataca gctgctttct cacttgtgta tccagtatgc attaccaaag
     3601 tcacttagtg tggctcgctt agctgtcaat gttatgggga ctttgctaac agttctgaca
     3661 caagctaagc ggtactcgtt tttcatgcca actcttccaa gtttggtctc cttttgtcga
     3721 gcatttcctc cactgtatga ggatattatg tctttgctaa ttcaaatagg acaagtgtgt
     3781 gcctctgatg ttgccactca gacaagagac attgatccaa tcattacacg tcttcaacaa
     3841 ataaaggaga aacctagtgg atggtctcaa atttgtaagg atccatctta caaaaatgga
     3901 tccagggaca ctggaagcat ggatcctgat gtccagctct gtcattgtat tgaaagcaca
     3961 ataattgaaa taataaacat gagtgttagt ggaatttaaa aaaagtttta agtgcagcca
     4021 cttgctatac tgaatctgga ctttatgaga actctaaact gaatgagaat agtgagatct
     4081 tggaattgct gaagtgactc aattcagcat gaggataatt tagagctctc tgagaattat
     4141 acttgtttga ttggcatatc tttggatctg ctctgatggt atgtttatat tgtagcagct
     4201 gaacttcttt tccactggag acactttaag aaacttgtca ctagaaaagg attggttcct
     4261 gtacttagca tttgacgtga agaaagattg ccaggccttt aatttaattg cttaaaaaaa
     4321 tgagcctgtg gatatccctc atatttgtga gctttcaaca gttttcaaca aagagaggag
     4381 aggaaggaga aagagggatg tagggcagga accatttaga aaaaattacc atttaagtac
     4441 acagaaatct tacagacttg taatgcaaat aacagtatta caggttgaac ttctaatttg
     4501 ttagagacag tagtaggatg gctttaaaaa aaaaaaaaaa aaagcaggta aggcaggtgt
     4561 ggtggagcat gccttaaatc ccagcctagg gagaaaggga gaggcaggca gacctttgac
     4621 caggccagcc tggttcacgt agtgagttcc aggaaagtca gagctacata atggaccctg
     4681 tccagactac taaatgactg ccttggaatt acagatgaag atacaaagat ttcacaaatc
     4741 tgcttcaatt tttcccaata tatgaagcca tatgtttaaa gagatacttg aattctttga
     4801 aattttaaga tactgattgt agttacagta acatctttgt gcaaagaaga acctgaaagt
     4861 aaatttcatt tattcttttt aaaatttatt tttgtaatac tgtattatct agttctcaga
     4921 ggagcaaaga tgtatcaaat taaatgaact ttagagcaat aaaccccaat agtgctcttg
     4981 gttcatcagc aggattataa ttcacatttt actttgagga gatctttgag taagaaaata
     5041 cagtatttga acctcaggaa aaattataat gtggaaaatg ctgtgttgct gactttttca
     5101 gccctctgtt aggagcttca cgtttaagga gatgcattca gataaccata atcatttttg
     5161 taaaattaag tacctatata caaggtactt ctttgctctt tgagaaatac ctcaatcata
     5221 tgtcacccta ctcagagcgg acctctggtt aaagaaggta gtaagctaaa aggaaagtta
     5281 tccctccccc cacaaaggaa cttagcttca tcctttcctc tcgtacatag tcacatctca
     5341 tttttctttg tcactcctga ccctacctca tgaaggtgtt ctattaaaac aagtttatag
     5401 ctgtttccaa tcatgaagta catcgtatca tgcatggtgg aatatatata actttttatt
     5461 agatgcttaa tgttcaatta attaattttg atgtgaagag taaaagaata tgctttaaag
     5521 atataccaca agaattttcc tatttttaaa tgaggcagtt ctgaagtctc ttaagattaa
     5581 atacaactgc tcccgttttg tttgtaaatg agacctttct ggaagttttt ctgtgaatag
     5641 tagaatcctt taggaattct gaattatttg aagtatgttt tgtaatgaaa tacagtacac
     5701 attttgtgga tcaattttca aagactagtc ataacctact gtgttaaagt aataacatag
     5761 cctgtttttc atccaatttg ttgatgatgt aaataaaata tgtaaataat attagtaaat
     5821 gttaatattc atatatctta agttaaggtt ataagctttg tcacaatgtg atttttttta
     5881 ttcaagtcaa aacagatgtg tgcaactatt ttggatattg atttataaac attcattctt
     5941 taacaatgaa
//
