LOCUS       NM_175153               3183 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus integrator complex subunit 14 (Ints14), transcript
            variant 1, mRNA.
ACCESSION   NM_175153 XM_917841
VERSION     NM_175153.5
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3183)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   2  (bases 1 to 3183)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   3  (bases 1 to 3183)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122463.4.
            
            On Jan 24, 2023 this sequence version replaced NM_175153.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK032095.1, SRR7345562.1525098.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-397               AC122463.4         15944-16340
            398-702             AC122463.4         16777-17081
            703-980             AC122463.4         19409-19686
            981-1088            AC122463.4         21773-21880
            1089-1244           AC122463.4         27056-27211
            1245-1363           AC122463.4         27775-27893
            1364-1506           AC122463.4         28301-28443
            1507-1599           AC122463.4         30700-30792
            1600-1744           AC122463.4         33220-33364
            1745-1878           AC122463.4         34858-34991
            1879-1997           AC122463.4         37072-37190
            1998-2063           AC122463.4         39061-39126
            2064-3183           AC122463.4         40942-42061
FEATURES             Location/Qualifiers
     source          1..3183
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 35.02 cM"
     gene            1..3183
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /note="integrator complex subunit 14"
                     /db_xref="GeneID:69882"
                     /db_xref="MGI:MGI:1917132"
     exon            1..397
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /inference="alignment:Splign:2.1.0"
     exon            398..702
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /inference="alignment:Splign:2.1.0"
     exon            703..980
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /inference="alignment:Splign:2.1.0"
     CDS             759..2306
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /note="isoform 1 is encoded by transcript variant 1;
                     UPF0464 protein C15orf44 homolog; von Willebrand factor A
                     domain containing 9; von Willebrand factor A
                     domain-containing protein 9"
                     /codon_start=1
                     /product="integrator complex subunit 14 isoform 1"
                     /protein_id="NP_780362.2"
                     /db_xref="CCDS:CCDS40668.1"
                     /db_xref="GeneID:69882"
                     /db_xref="MGI:MGI:1917132"
                     /translation="MPTVVVMDVSLSMTRPVSVEGSEEYQRKHLAAHGLTMLFEHMAT
                     NYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQE
                     WGGAIPCQVVLVTDGCLGIGRGSLRHSLATQNQRSESNRFPLPFPFPSKLYVMCMANL
                     EELQSTDSLECLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKC
                     GHLTADVQVFPRPEPFVIDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPI
                     ALNKEGDEVGAGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVALVQLGPEWHG
                     MLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQ
                     PKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFL
                     DLLKGVADMLERECTLLPDTAHPDAAFQLTHAAQQLKLASTEYAIYDHNITPLHTDFS
                     GSSTERM"
     exon            981..1088
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1244
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1363
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /inference="alignment:Splign:2.1.0"
     exon            1364..1506
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /inference="alignment:Splign:2.1.0"
     exon            1507..1599
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /inference="alignment:Splign:2.1.0"
     exon            1600..1744
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /inference="alignment:Splign:2.1.0"
     exon            1745..1878
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..1997
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /inference="alignment:Splign:2.1.0"
     exon            1998..2063
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /inference="alignment:Splign:2.1.0"
     exon            2064..3183
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2821..2826
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /note="hexamer: ATTAAA"
     polyA_site      2859
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /note="major polyA site"
     regulatory      2891..2896
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /note="hexamer: AATATA"
     regulatory      2896..2901
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /note="hexamer: AATACA"
     polyA_site      2911
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
     polyA_site      2925
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
     regulatory      3162..3167
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
                     /note="hexamer: ATTAAA"
     polyA_site      3183
                     /gene="Ints14"
                     /gene_synonym="2010321M09Rik; Vwa9"
ORIGIN      
        1 gcacggccct taagttccgg ctatggcgcg cggacggaag gtttaagcgg acggacagag
       61 gctggagatg ggctccgggt aagtcaggga atgtgcctgt tgagggctgt gtttcgatgg
      121 cggttggggt tacaggggaa ggagtggaag gaacaacaca gggcgggcgg cggaccttct
      181 ctgaggcccg cgtagggtgg cggtctcagg ggcgctggct ccagggcctg cgacaggcct
      241 gccctctgtg tggcccgggt cttgtaagca gcaggattcc gcgcttgggg ccgtgtttct
      301 tcctcccctg agagtcttcc gtccctggac cctgagactt ccgtcccctc tttccccgag
      361 agttccatac aacaaatgtt ttgggctcgt tttaaagttt tgtggctaag cccagactgc
      421 ttgagtgaaa cagccttcag ggacgttcca ttctttcgtt tatcccagtg cttacaaccc
      481 aaaaacaaaa ttggattgcc acaagtcggc cacggctgag gaagtgcact cgggccctga
      541 cacaaatgca tcagtcagga gaaagagcca gcttctcagg tgtcttcaga gaaggccaga
      601 ctgacagctg cggtcaccca ttgcagtgct agcagcaatt tcatggactg gaagtgcttg
      661 ttggtacttg atccagaaaa ctgtttctca atctcttaag agcatttctc tggttgtagc
      721 tggctgtgtg ctgagaggga gtgctagaat tgtccatcat gcccactgtg gtggtaatgg
      781 atgtgtccct gtccatgacc cgacctgtgt ctgtcgaggg ctctgaggaa taccagcgga
      841 agcacctggc tgcccatggc ctgacgatgc tatttgaaca catggccaca aattacaagc
      901 ttgaattcac agcgctggtg gtgttttcgt cactgtggga gctgatggtc ccctttacga
      961 gagactacaa caccctgcag gaagcactga gtaacatgga tgattatgac aaaacctgct
     1021 tggagtctgc attagtcggc gtttgcaata ttgtccagca agaatggggt ggagcgattc
     1081 cttgccaggt tgttctggtg actgatggct gtcttggtat tggcaggggg tcactgcgac
     1141 actccctagc tactcagaat caaagaagtg agagcaacag gtttccactc cccttccctt
     1201 tcccatctaa gttatatgtc atgtgcatgg cgaacttgga ggagcttcag agcaccgatt
     1261 ccttggaatg ccttgaacga ctcatagact taaataatgg tgaagggcaa atttttacta
     1321 ttgatggccc cctgtgtttg aaaaatgtgc aatctatgtt tggaaagctg atagatctgg
     1381 cgtacacacc tttccatgct gttctcaagt gtggccacct aacggctgat gtacaagtct
     1441 tccccaggcc agagcccttt gttatagatg aagaaattga ccccatccct aaagtcatta
     1501 acacagactt ggaaatagtg ggctttattg acatagctga tatttccagc cccccagttt
     1561 tgtccaggca tttggtcttg cccatagcac ttaacaaaga aggtgacgag gtgggtgctg
     1621 gcatcactga tgacaatgaa gatgagaatt cagccaatca gattgctggc aaaataccca
     1681 acttctgtgt cctgctccac ggcagcctga aggtggaagg aatggtggca cttgtccaac
     1741 tagggcctga atggcatgga atgctctact cccaagcaga cagcaagaag aaatcaaacc
     1801 tcatgatgtc tctcttcgag cctggcccag aacctctccc gtggcttggg aaaatggccc
     1861 agttggggcc catctcagat gctaaagaaa atccttatgg ggaggatgac aacaagagcc
     1921 cattccccct gcagcccaaa aacaaacgaa gttatgccca gaatgtgact gtctggatca
     1981 aaccaagtgg cctgcagaca gatgtacaga agatcttaag aaatgcaagg aagctccctg
     2041 aaaaaacaca gacattctat aaggagctga acaggttacg aaaagctgcc ttagcctttg
     2101 gtttcctgga cctgcttaaa ggggtggccg acatgctgga gagggagtgt accctgctgc
     2161 cggacacagc ccacccagac gccgcattcc agctcaccca cgctgcccag cagctcaagc
     2221 tggccagcac tgagtatgcc atatatgacc acaacatcac acccctgcac acagacttct
     2281 cagggagcag cactgaaaga atgtgatgct gagctctgga gcgttccttc acgttcactt
     2341 tgtctgaagg caatttagag ttaaaacctt ctccagctct atcagaaaca gcatttgccc
     2401 gtctgaatgt ttctactgca gtctgagaaa ggtctgaagg ctggttgtct ggggctcagt
     2461 ctctaggtcc agaaacagcc tttgttccat gataggcaca gctcctgaga agcttggaca
     2521 gatgaggagc gagcgcagga agaagcctag gcagccaggg ccgtctagca tccagaaagc
     2581 gactcttcat gtctcaatta caaggacatt cttaaacttc tgtgcttgga agaagcaatc
     2641 cagatgtcta gaacttgcct aagtacaaac ccgatgccat tgagtttcaa tttttttctt
     2701 agaacttgtt aaaatacaag tggcaatgct caggtgcttc tggtgtatcc caaggtacac
     2761 atttttagac tgtaaccaca atatgtgtaa aatcactcct gttcatgttt ttaaatgaaa
     2821 attaaatatt tgattttcta tagtgattgc acttagaaac aaatggtgtt ttgatctatc
     2881 ttatcccttg aatataatac agcttccaaa atgtcagact cctaagaagc aatgtctctc
     2941 gggtcctgtg taacttccta gtttctgaca gtgatcaagc tttgtacctc agcaaggttc
     3001 tggccagtgg ttctgagagc actgatggga gagtcaggcc tcccaggctg tgcctgcaca
     3061 gtgctcaccc agtgcttcgt gactgccttc agtactccct taggctcctg ccagagtcac
     3121 tgtgcctgaa caaagcactt tacccattta aaactcatga gattaaatga tgtttaagca
     3181 caa
//
