LOCUS       NM_138757               3071 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus integrator complex subunit 13 (Ints13), transcript
            variant 2, mRNA.
ACCESSION   NM_138757
VERSION     NM_138757.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3071)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3071)
  AUTHORS   Jodoin,J.N., Sitaram,P., Albrecht,T.R., May,S.B., Shboul,M.,
            Lee,E., Reversade,B., Wagner,E.J. and Lee,L.A.
  TITLE     Nuclear-localized Asunder regulates cytoplasmic dynein localization
            via its role in the integrator complex
  JOURNAL   Mol Biol Cell 24 (18), 2954-2965 (2013)
   PUBMED   23904267
REFERENCE   3  (bases 1 to 3071)
  AUTHORS   Jodoin,J.N., Shboul,M., Sitaram,P., Zein-Sabatto,H., Reversade,B.,
            Lee,E. and Lee,L.A.
  TITLE     Human Asunder promotes dynein recruitment and centrosomal tethering
            to the nucleus at mitotic entry
  JOURNAL   Mol Biol Cell 23 (24), 4713-4724 (2012)
   PUBMED   23097494
REFERENCE   4  (bases 1 to 3071)
  AUTHORS   Mu,X., Zhao,S., Pershad,R., Hsieh,T.F., Scarpa,A., Wang,S.W.,
            White,R.A., Beremand,P.D., Thomas,T.L., Gan,L. and Klein,W.H.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
REFERENCE   5  (bases 1 to 3071)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY741532.1, CF167981.1, CD560819.1, CK618181.1, BI986549.1,
            CF949591.1, AC124128.11 and BE685943.1.
            
            On Mar 22, 2007 this sequence version replaced NM_138757.1.
            
            Transcript Variant: This variant (2) lacks an alternate in-frame
            exon compared to variant 1. The resulting isoform (2) has the same
            N- and C-termini but is shorter compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC026851.1, BC027229.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-535               BY741532.1         2-536
            536-978             CF167981.1         132-574
            979-1374            CD560819.1         186-581
            1375-1889           CK618181.1         68-582
            1890-2120           BI986549.1         16-246
            2121-2627           CF949591.1         64-570
            2628-2705           AC124128.11        71789-71866         c
            2706-3071           BE685943.1         1-366               c
FEATURES             Location/Qualifiers
     source          1..3071
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 77.7 cM"
     gene            1..3071
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /note="integrator complex subunit 13"
                     /db_xref="GeneID:71177"
                     /db_xref="MGI:MGI:1918427"
     exon            1..535
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            536..771
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     CDS             547..2745
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /note="isoform 2 is encoded by transcript variant 2; cell
                     cycle regulator Mat89Bb homolog; protein asunder homolog;
                     asunder, spermatogenesis regulator; likely orthologue of
                     H. sapiens chromosome 12 open reading frame 11 (C12orf11);
                     spermatogenesis associated 30; spermatogenesis-associated
                     protein 30"
                     /codon_start=1
                     /product="integrator complex subunit 13 isoform 2"
                     /protein_id="NP_620096.2"
                     /db_xref="CCDS:CCDS39710.1"
                     /db_xref="GeneID:71177"
                     /db_xref="MGI:MGI:1918427"
                     /translation="MKIFSESHKTVFVVDHCPYMAESCRQHVEFDMLVKNRTQGIIPL
                     APISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELM
                     AALATVGPPNPRADPECCSILHGLVAAVETLCKITEYQHEARTLLMENAERVGNRGRI
                     ICITNAKSDSHVRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLV
                     SDRPKKELSPVLTSEVHSVRAGRHLATKLNVLVQQHFDLASTTITNIPMKEEQHANTS
                     ANYDVELLHHKDAHVDFLRSGDSHSGSSSREGPFKETVTLKWCTPRTNSIELHYCTGA
                     YRISPVDVNSRPSSCLTNFLLNGRSVLLEQPRKSGSKVISHMLSSHGGEIFLHVLSSS
                     RSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLDPRYKIDASLEIPLERAKD
                     QLEKHTRYWPMIISQTTIFNMQAVVPLAGVIVKESLTEEDVLNCQKTIYNLVDMERKN
                     DPLPVSTVGTRGKGPKRDEQYRIMWNELETLVRAHISNSEKHQRVLECLMACRSKPPE
                     EEERKKRGRKREDREDKSEQAGKEHGTEKARPDADRLKGILERGKEELAEAEVIKDSP
                     DSPEPPNKKPLVETDETPHMEKSKGPVSLLSLWSNRINTANSRKHQEFAGRLNSVNNR
                     AELYQHLKEENGEEVGLTGGPRTAIPFLKCPRSPVVNRMETTENGKASRQ"
     exon            772..846
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            847..1049
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1130
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1221
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..1350
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..1435
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            1436..1525
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            1526..1615
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..1794
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            1795..1965
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            1966..2120
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            2121..2351
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            2352..2491
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            2492..2627
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            2628..2705
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     exon            2706..3059
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3029..3034
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /note="hexamer: AATAAA"
     regulatory      3038..3043
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /note="hexamer: ATTAAA"
     polyA_site      3053
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
     polyA_site      3059
                     /gene="Ints13"
                     /gene_synonym="4933424B01Rik; Asun; Spata30"
                     /note="major polyA site"
ORIGIN      
        1 ttctctcctc gcccccctct caaggttttg ctctgccgct cgcacactct cgcgtgtttt
       61 ccgaggggct accggcccgg actggaggcg gagaggggag gttgggtggg taggctctgc
      121 ctgtccagag ccgaggctgg cttgtcccgg ccgtggctta gtactttgtg gggggatctc
      181 tcgggtcgtc ctgaccgttc ttccctacgg ttgattggga acaaatgtta aaggcttttt
      241 ttttcccctc acttgctccg ccctcttccg gttcggcctc tggtggcttc taaggagaag
      301 ggaagatggc ggggctgtgc gagagcgccg tgcgcacgcg cgagtccgag tgcgctcttg
      361 tgcttgcacg cgcatgcgcg cgcccctgcg tttaagcagc cggagtgttg ggagatgagc
      421 cgggcagtca gtcttctgcg ggttgtacca gaccgactgt gcgccgactc cccacccacc
      481 ctcgtccgcc ttctctctca gcctccgttc attcactgca ggaccaggca cgaaagttaa
      541 aacaaaatga agattttttc tgaatctcat aaaacagtgt ttgttgtgga tcactgccca
      601 tacatggcag aatcctgtag gcagcatgtg gagtttgata tgctggtgaa gaacaggacc
      661 caaggcatca tccctttggc tcccatctcc aaatccttgt ggacttgctc agtagaatct
      721 tccatggaat attgtagaat aatgtatgac atatttcctt tcaaaaagct ggtgaatttc
      781 attgttagtg attcgggagc acatgtttta aattcttgga ctcaagaaga ccaaaactta
      841 caggagctaa tggcagcact agctacagtg gggcctccta accctcgggc agatccagag
      901 tgctgcagca tcctgcatgg tcttgttgca gcagtggaaa ccctttgcaa gattaccgaa
      961 taccagcatg aggctcgcac tttactcatg gagaatgcag aacgagttgg gaatagagga
     1021 cggataatct gcatcacaaa tgcaaaaagt gatagtcatg tccgaatgct cgaagattgt
     1081 gtccaggaaa caattcatga gcataacaag cttgctgcaa attcagatca tctcatgcag
     1141 attcaaaaat gtgagttggt cttgattcac acctacccag ttggtgaaga tagccttgtg
     1201 tctgaccgtc ctaaaaaaga attgtcccca gttttgacca gtgaagtcca cagtgtccga
     1261 gctgggcggc atcttgctac caagttgaat gttctagtac agcaacattt tgacttggct
     1321 tcaacgacca tcacaaacat tcctatgaag gaagagcagc atgccaacac atctgccaac
     1381 tatgacgtgg agctacttca tcacaaagat gcacatgtag atttcctgag aagtggtgac
     1441 agccactctg ggagcagcag cagagaaggg ccatttaagg agacagtaac cctgaagtgg
     1501 tgcacaccca ggaccaacag cattgaattg cactattgca ctggagctta ccggatttca
     1561 cctgtggatg taaatagtag accttcttcc tgccttacta atttcctcct caatggtcgg
     1621 tctgtgttgc tggagcagcc acgaaagtca ggctccaaag tcatcagtca catgcttagc
     1681 agccatggag gagagatctt tctgcatgtc cttagcagtt ctcgatccat tctggaagat
     1741 ccgccttcaa ttagtgaggg ctgtggagga agagttacag actaccggat tacagatttt
     1801 ggtgaattta tgagggaaaa caggttaact ccttttctag accccagata taaaatcgat
     1861 gcaagtctag agatcccgtt ggagcgtgca aaggatcagt tagaaaagca cacccgttac
     1921 tggcccatga ttatttcaca aaccaccatt ttcaacatgc aagcggtagt tccattagct
     1981 ggtgtcattg tgaaagagtc tttgacagaa gaggatgtgt taaactgtca gaagaccata
     2041 tacaacttag ttgatatgga aaggaagaat gaccctcttc ctgtttctac agtcggtacc
     2101 agaggaaagg gacctaaaag agatgaacag taccggatca tgtggaatga actagagact
     2161 ctcgtcagag cccatatcag caactctgag aagcatcaga gagtattgga gtgtctaatg
     2221 gcatgtagga gcaaaccccc agaagaagaa gagcggaaga agcgagggag gaagagggag
     2281 gacagggaag acaagtcgga acaagcaggg aaggagcacg gcacggaaaa ggcccggccg
     2341 gatgcagaca gattgaaagg gattttagaa cgagggaaag aagagttggc tgaagcagag
     2401 gtcataaagg actcacctga ttctccagaa cctccaaaca aaaagcccct tgttgaaacg
     2461 gatgagacac cacacatgga aaagtctaaa gggccagtgt ccttattatc cttgtggagt
     2521 aacagaataa acactgccaa ttccagaaag caccaggagt ttgctgggcg tttgaactct
     2581 gtcaataaca gagcagagct gtatcaacac cttaaggagg aaaatggtga ggaggttgga
     2641 ctgactggag gaccccgaac tgcaatccct ttcttaaagt gcccacgttc tcctgttgtg
     2701 aataggatgg agacaacaga aaatgggaaa gccagccgcc agtgaagagt gacttgagaa
     2761 accaaattta gaatattgtg aaaaatattt tgggcagaat ttgatataag tacttttaca
     2821 gcaagattgt atagctatgt tgtctggact ggtttttaca tttttagaga atttcaatga
     2881 attatctttt ttgtactaat tctgagattg gcagagtcaa aatatataca ttggagattt
     2941 gccctcccag accacacagt ttattttatg gtaaaaggtg ttccctctgg aaatgttttt
     3001 ttaaaaactc ttaggcttct ctttgccaaa taaaactatt aaaatgtttg aaatgccaaa
     3061 aaaaaaaaaa a
//
