LOCUS       NM_026748               7106 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus integrator complex subunit 1 (Ints1), mRNA.
ACCESSION   NM_026748 XM_132471
VERSION     NM_026748.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7106)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   2  (bases 1 to 7106)
  AUTHORS   Hata,T. and Nakayama,M.
  TITLE     Targeted disruption of the murine large nuclear KIAA1440/Ints1
            protein causes growth arrest in early blastocyst stage embryos and
            eventual apoptotic cell death
  JOURNAL   Biochim Biophys Acta 1773 (7), 1039-1051 (2007)
   PUBMED   17544522
REFERENCE   3  (bases 1 to 7106)
  AUTHORS   Nakayama,M., Iida,M., Koseki,H. and Ohara,O.
  TITLE     A gene-targeting approach for functional characterization of KIAA
            genes encoding extremely large proteins
  JOURNAL   FASEB J 20 (10), 1718-1720 (2006)
   PUBMED   16807365
REFERENCE   4  (bases 1 to 7106)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC167333.3.
            
            On Aug 31, 2021 this sequence version replaced NM_026748.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB257854.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-343               AC167333.3         69155-69497
            344-634             AC167333.3         70251-70541
            635-831             AC167333.3         72035-72231
            832-969             AC167333.3         72336-72473
            970-1129            AC167333.3         72653-72812
            1130-1235           AC167333.3         72908-73013
            1236-1428           AC167333.3         73100-73292
            1429-1574           AC167333.3         73394-73539
            1575-1716           AC167333.3         73638-73779
            1717-1893           AC167333.3         74590-74766
            1894-2002           AC167333.3         75422-75530
            2003-2123           AC167333.3         75845-75965
            2124-2201           AC167333.3         76333-76410
            2202-2359           AC167333.3         76951-77108
            2360-2456           AC167333.3         77330-77426
            2457-2548           AC167333.3         78308-78399
            2549-2609           AC167333.3         78532-78592
            2610-2807           AC167333.3         79588-79785
            2808-2937           AC167333.3         80032-80161
            2938-3117           AC167333.3         80422-80601
            3118-3267           AC167333.3         80675-80824
            3268-3447           AC167333.3         81842-82021
            3448-3552           AC167333.3         82111-82215
            3553-3720           AC167333.3         82334-82501
            3721-3832           AC167333.3         82695-82806
            3833-3994           AC167333.3         83385-83546
            3995-4141           AC167333.3         84029-84175
            4142-4240           AC167333.3         84648-84746
            4241-4365           AC167333.3         84958-85082
            4366-4620           AC167333.3         85439-85693
            4621-4780           AC167333.3         86240-86399
            4781-4921           AC167333.3         86594-86734
            4922-5108           AC167333.3         86854-87040
            5109-5232           AC167333.3         87118-87241
            5233-5363           AC167333.3         87638-87768
            5364-5451           AC167333.3         88298-88385
            5452-5678           AC167333.3         88468-88694
            5679-5802           AC167333.3         88829-88952
            5803-5936           AC167333.3         89519-89652
            5937-6129           AC167333.3         89730-89922
            6130-6257           AC167333.3         90628-90755
            6258-6370           AC167333.3         91256-91368
            6371-6484           AC167333.3         92004-92117
            6485-6555           AC167333.3         92538-92608
            6556-6647           AC167333.3         92800-92891
            6648-6757           AC167333.3         93010-93119
            6758-7106           AC167333.3         93196-93544
FEATURES             Location/Qualifiers
     source          1..7106
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 78.8 cM"
     gene            1..7106
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /note="integrator complex subunit 1"
                     /db_xref="GeneID:68510"
                     /db_xref="MGI:MGI:1915760"
     exon            1..343
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             286..6873
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /note="int1"
                     /codon_start=1
                     /product="integrator complex subunit 1"
                     /protein_id="NP_081024.4"
                     /db_xref="CCDS:CCDS57399.1"
                     /db_xref="GeneID:68510"
                     /db_xref="MGI:MGI:1915760"
                     /translation="MNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQASESKTTST
                     LLKPAPSGLPSERKRDASASLSGTSALTGLTKRPKLSSTPPLSALGRLAEAAVAEKRA
                     ISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVTRAKPDSTL
                     YLSLMYLAKIKPNIFATEGVIEALCSLLRRDASVNFKAKGNSLVSVLACNLLMAAYEE
                     DENWPEIFVKVYIEDSLGERIWVDSPHCRTFVDNIQTAFNTKMPPKSVLLQGEGARSG
                     GELGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRPRYDELTESVEEYVLDM
                     LRDQLNRRQPIDNVSRNLLRLLTATCGYKEVRLLAVQRLEMWLQNPKLTRPAQDLLMS
                     VCMNCNSHGSEDMDVISHLIKIRLKPKVLLNHYMLCIRELLNAHKDNLGTTIKFVIFN
                     ELSNARNPNNMQILYTVLQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQT
                     KHEINFQAFCLGLMQERKEPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGVAW
                     DKGEKRNLEVLRTFQNQIAAIQRDAVWWLHTVVPSVSKLAPKDYVHCLHKVLFTEQPE
                     TYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRVLVIGLSRELPLGPADAMELADHLV
                     KRAAAVQADDVEVLKVERIQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAW
                     PLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMINREL
                     QISQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVK
                     ALNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCE
                     FLLHDAADSTASGEEDDEGESREQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCE
                     VLDYFLRRLGSSQVASRVLAMKGLSLVLSEGGLRDKEEKEPPMEEDIGETDALQGYQW
                     LLRDLPRLPLFDSVRTTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQGPHSDLA
                     LDVARLVVERSTIMAHLFSKPSCSTASDAVLSALLSVFSRYVRRMRKSKEGEEVYSWS
                     ESQDQVFLRWSSGETATMHILVVHAMVILLTLGPPRSGDSEFSELLDIWFPEKKPLPT
                     AFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSK
                     LLQYLDQAVAQDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDS
                     TEAPKPESSPEPPPGQGRTRAGTQVPVLGPEDDLAGIFLQIFPLSPDPRWQSSSPRPL
                     ALALQQALGQELARVRQGNPEVPGITVRLLQAMTTLLSSPHGGTLALAMHHSHFLSCP
                     LMRQLYQYQRAVPQDTGFSSLFLKVLMQILQWLDSPAVEDGPLQAQLKLFATRYSARH
                     RISDVRSGLLHLADALSFHGDLEVANSTARAVIATLRSGEKCPVEPELISKVLRGLIE
                     VRSPHLEELLTALFSATTETSCPSPASGPIVVVSSLLLQEKEELLGPSKQEVEGASTE
                     AMRLGPASGLLVDWLETLDPEVVCSCPDLQWKLLFSRRKGKGHISAQVLSFRPYLLAL
                     LTHQASWSTLHCCIRVLLGKSREQRLDPSASLDFLWACIHVPRIWQGRDQRTPQKRRE
                     ELVLHVQGPELLSLVELILSEAETRSQDGDSAARTLIQTRLPLLLSCCRSNDESIGKV
                     TEHLTSCIQQWGDSVLGQRCRDLLLQLYLQRPEVRVPVPEVLLQSEGATSSSICKLDG
                     LVHRFITLLADTSDSRSSESRVADANMACRKLAVAHPVLLLRHLPMIAALLHGRTHLN
                     FQEFRQQNHLAFFLHVLGILELLQPRVFQSEHQGALWDCLRSFIRLLLNYRKSSRHLA
                     PFISKFVQFIHKYVGCSAPAAVAFLQKHAEPLHDLSFDNSDLVMLKSLLAGLSLPSRD
                     GRTDQGLDEEGEDERSAGSLPLVSVSLSTPLTVADVAPHMKRLSRGRAVEDVLETLSD
                     IDEMSRRRPEVLGFFSTNLQRLMSSAEESCRNLAFSLALRSIQNNPSIAADFLPTFMY
                     CLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGVYGQIDTSAQISEALKILH
                     MEAVM"
     exon            344..634
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            635..831
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            832..969
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1129
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1235
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1428
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1429..1574
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1575..1716
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1717..1893
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1894..2002
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2003..2123
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2124..2201
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2202..2359
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2360..2456
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2457..2548
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2549..2609
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2610..2807
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2808..2937
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2938..3117
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3118..3267
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3268..3447
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3448..3552
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3553..3720
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3721..3832
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3833..3994
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3995..4141
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4142..4240
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4241..4365
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4366..4620
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4621..4780
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4781..4921
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4922..5108
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            5109..5232
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            5233..5363
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            5364..5451
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            5452..5678
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            5679..5802
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            5803..5936
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            5937..6129
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            6130..6257
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            6258..6370
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            6371..6484
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            6485..6555
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            6556..6647
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            6648..6757
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            6758..7106
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7086..7091
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /note="hexamer: AATGAA"
     polyA_site      7106
                     /gene="Ints1"
                     /gene_synonym="1110015K06Rik"
                     /note="major polyA site"
ORIGIN      
        1 agtttgcact tccggagcgc ccgtgtctcg ggtctgcaga gtgctgcacc ggaggtgagg
       61 ggcctttgca cccaggtgaa gtccgctccc tgcggtgaca tccgtctccg cagtcggccg
      121 cgtgtgtgcc gcacttggcc cctttctgtg accccggtag gcggccctgg gcactcggtc
      181 cagtggcccc ggtgcgaggg atgaatgact gagcgagcga gtgactcccg ccgcctcctc
      241 ccaggtgaag gcgcttcctc taggggcgcc cgggccgcgg ggaggatgaa tcgagccaag
      301 cccaccaccg tacggagacc cagcgcggcc gccaagccct cagggcaccc tccccctggg
      361 gactttattg ctctggggtc caagggtcag gccagtgaat caaagacaac gtccaccctg
      421 ctgaagccag ccccttctgg gctaccctca gagcgcaaga gagatgcttc agcttctctg
      481 tctgggacct ctgcgctgac cggcctcact aagcgcccca aactgtcctc cactccccca
      541 ctgagcgccc tgggacgtct ggctgaagcc gcagttgcag agaagcgagc catttctcca
      601 tcgattaagg agccatctgt ggtgcccatt gaagttctgc ccacagtgct gctggacgag
      661 attgaagccg ctgagctgga gggcaatgac gacaggatcg agggagtgct gtgcggggca
      721 gtgaagcagc tgaaggtgac gcgggccaag cctgacagca cgctctacct gagcctcatg
      781 tacctggcca agatcaagcc caacatcttt gccacagagg gtgtcatcga ggccctgtgc
      841 agcctcttgc ggagggacgc ctctgtcaac ttcaaggcca aagggaacag cctcgtgtct
      901 gtactggcct gcaaccttct catggccgcg tacgaggagg acgagaactg gcctgagatc
      961 ttcgtgaagg tatacattga agactcgctg ggcgagcgga tctgggtaga cagccctcac
     1021 tgccgcacct tcgtggacaa catccagaca gccttcaaca ccaagatgcc cccaaagagc
     1081 gtcctgctgc agggggaggg ggcacgcagt ggtggtgagc ttggtgcagg cagcagcccc
     1141 cacccctcac tcacagagga ggaggacagt cagacggagc tgctgattgc cgaggagaaa
     1201 ctgagtcctg agcaggaggg gcagctcatg ccaaggccta ggtacgatga actcacagag
     1261 agcgtggaag aatatgtcct ggacatgctg cgtgaccagc tgaaccggcg ccagcccatc
     1321 gacaacgtgt ccaggaacct cctgcggctg ctcacggcca cctgtggcta caaggaggta
     1381 cggttgctgg ctgtgcagcg gctggagatg tggctgcaga accccaagtt gaccaggcca
     1441 gcgcaggacc tgttgatgtc tgtgtgcatg aactgcaact cccatgggtc agaagacatg
     1501 gatgtcatct ctcacctgat caagatccgc ctcaagccca aggtgctcct caaccactat
     1561 atgctctgca tcagggaact gctgaacgcg cacaaggaca acctgggtac cactatcaag
     1621 tttgtgatct tcaatgagct ctcgaatgct cgaaacccca acaacatgca gatcctgtac
     1681 acagtgctgc agcacagctc tgagctggca cccaagttcc tagccatggt gttccaggac
     1741 ctgctgacca acaaggatga ctacctccgc gcctctaggg ccctgctgcg ggagatcatc
     1801 aagcagacca agcacgagat caacttccaa gccttctgcc tggggctcat gcaggagcgc
     1861 aaggagccgc agtacctgga gatggaattt aaggagcggt ttgtggttca catcacggat
     1921 gtgctagctg tgtccatgat gctgggcatt acagcccagg tgaaggaggc tggagtcgcc
     1981 tgggacaaag gagagaagag aaacctcgag gtgctccgga cgttccagaa ccagattgcg
     2041 gctatccagc gggatgcggt gtggtggctt cacactgtcg tcccctccgt cagcaaactc
     2101 gcccccaagg attatgtgca ttgcctccac aaggtgctct tcaccgagca gcccgagacc
     2161 tactacaagt gggacaactg gccacccgag agcgaccgca atttcttcct gcgcctctgt
     2221 tcagaggtcc ccattctgga ggacacgctg atgagagtcc tggtcattgg actgtcccga
     2281 gagctgcctc ttggccctgc agatgccatg gaactggctg accaccttgt gaagcgagcc
     2341 gcagctgtgc aggctgatga tgtggaagtt ctgaaggtgg agcggatcca gctgatagat
     2401 gcggttctga acctgtgcac ctaccaccat cctgagaata tccagctgcc cccggggtat
     2461 cagcccccaa accttgccat ctccaccctc tactggaagg cttggcccct actgctggtt
     2521 gtcgctgcct tcaacccaga gaacattggc ctggccgcat gggaggagta tccaacgttg
     2581 aagatgctca tggagatggt gatgaccaat aactactcat acccaccgtg cacgctgacg
     2641 gacgaggaga cgaggacgga gatgatcaac cgggaactgc agatctctca gcgggagaag
     2701 caggagatcc tggcctttga gggtcacctg gccgccgcct ccaccaagca gaccatcacc
     2761 gagagcagca gcctcctcct gtcccagcta accagcctag acccccaagg ccctccccgg
     2821 aggccacccc ctcacatcct ggaccaggtg aaggccctca accaatctct gcgccttggg
     2881 cacctgttgt gccgcagccg taacccagac ttcctgctgc acatcatcca gcgccaggcc
     2941 tcctcccagt ccatgccgtg gctagcggat ctggtgcagt ccagtgaagg atcgctggac
     3001 gtgctccctg tgcagtgcct gtgcgaattc ctgctgcacg atgcagctga ctccacagcc
     3061 tcaggggagg aggatgacga gggcgaaagc cgggagcaga aggccaagaa gcgacagagg
     3121 cagcagaaac agcggcagct gctgggccgc ctgcaggatc tgctgctagg cccgaaagca
     3181 gatgagcaga ccacatgtga ggtgcttgac tacttcctcc ggcgtttggg ctcctcacag
     3241 gtggcctccc gggtgttggc catgaagggc ctgtcacttg tgctgtcaga gggtggtctt
     3301 cgtgacaagg aggagaaaga gccccccatg gaggaggaca ttggggagac ggatgctcta
     3361 cagggctatc agtggttgct gcgggacctg cccaggctgc cgctgtttga cagcgtgagg
     3421 accaccacgg ccttggctct ccagcaggcc atccacatgg aaacggaccc ccagaccatc
     3481 agtgcctatc tcatctacct gtcccagcac acgccagtgg aggagcaggg cccacacagt
     3541 gacctggccc tggacgtggc ccggctggtc gtggagcggt ccaccatcat ggcgcacctc
     3601 ttctccaagc cctcctgcag caccgcttct gacgctgtac tcagcgccct gctgtctgtg
     3661 ttttcccgct atgtgcggcg catgcgcaag agcaaagagg gtgaagaggt ctacagctgg
     3721 tcggagtctc aggaccaagt gttcttgcgc tggagcagtg gggagacggc caccatgcac
     3781 atcctcgtgg tgcacgccat ggtcatcctg ctgacactgg gcccgccgcg ttctggtgac
     3841 agcgagttca gtgagttgct ggacatctgg tttccagaga agaagccttt gcccacagcc
     3901 ttcctggtgg acacgtcgga ggaggcgctg ctgctgcctg actggctgaa gctgcgaatg
     3961 attcgctctg aggtcccccg gcttgtggac gctgccctgc aggacctgga gccccagcag
     4021 ctgctgctct tcgtgcagtc ctttggcatc cccgtgtcca gcatgagcaa gctgctgcag
     4081 tacctggacc aggcggtagc ccaggacccc caaaccctgg agcagaacat catggacaag
     4141 aattacatgg cccacctggt tgaggtacag cacgagagag gtgcttctgg aggccagacc
     4201 ttccactcac tcctcacagc ctccctgcca ccccgacgag acagcacgga ggctcctaag
     4261 ccagaaagca gccctgagcc cccaccaggc cagggcagga ctcgggcagg gacgcaggtg
     4321 ccggtgcttg gccctgagga cgacttagct ggcatcttcc tacagatctt cccactgagc
     4381 ccggacccac ggtggcagag ctccagccca cgcccccttg ccctggcact gcagcaagcc
     4441 ctgggccaag agttggctcg tgtccgccag gggaaccccg aggtgccagg catcacagtc
     4501 cgccttctgc aggccatgac caccctgctg agctccccgc acggtggcac ccttgctctg
     4561 gctatgcatc acagccactt cctttcctgc ccactgatgc gccagctcta ccagtaccag
     4621 cgtgctgtcc cgcaggacac tggcttctcc tcgctcttcc ttaaagtgct catgcagatc
     4681 ctgcagtggc tggatagccc tgctgtggag gatgggccct tgcaggccca actcaagtta
     4741 tttgctactc gctattcagc aaggcacagg atcagcgacg tgcgtagtgg gctcctgcac
     4801 ttggctgacg ccctgagctt ccatggtgat ctggaggtgg ccaactccac cgcgcgggcc
     4861 gtcattgcca ccctgaggtc cggggagaag tgtcctgtgg agcctgagct catcagcaaa
     4921 gtcctccggg gcctcatcga ggtgcgctcc ccgcacttgg aagagttgct gacagcgctc
     4981 ttctcagcca ccacagagac ctcgtgcccg agcccagcct ctgggcccat tgtggtggtg
     5041 agctccttgc tgctacagga gaaggaagag ctcctgggcc ccagcaagca ggaggtggag
     5101 ggtgccagca cggaagccat gcgcctggga ccagcttctg ggctgcttgt ggactggctg
     5161 gagacgctgg accccgaagt ggtctgtagt tgccctgacc tacagtggaa gctgctcttc
     5221 tcacggagaa agggcaaagg ccacataagt gcccaggtgc tctccttccg cccctacctc
     5281 ctggccctcc tcacgcacca ggccagctgg tccacgctgc actgctgcat ccgtgtcctg
     5341 ctaggcaaga gccgtgagca gaggctcgac ccttcagcat ccctggactt cctctgggcc
     5401 tgtatccatg tcccccggat ctggcagggc cgggaccagc gcactccaca gaagcggcgg
     5461 gaggagttgg tgctccacgt gcagggccca gagctgctca gcctggtgga gcttatcctg
     5521 tccgaggcag agaccaggag ccaggatggg gacagtgctg cacgcaccct tatccagacc
     5581 cggctgcccc tgctgcttag ctgctgccgt agcaatgatg agagcattgg aaaagtgacc
     5641 gagcacctga ccagctgcat ccagcaatgg ggggacagtg tgctgggcca gcgctgccga
     5701 gacttgctgt tgcaactgta cctgcagcgg ccagaggtcc gggtgccagt gcccgaggtc
     5761 ctgctgcaaa gtgaaggtgc caccagcagc agcatctgca agctggacgg cctcgtccat
     5821 cgcttcatca cgctcctggc agacaccagc gactcccggt cttctgagag cagagtggct
     5881 gacgccaaca tggcctgccg gaagctggct gtggcccacc ccgtcctgct gctgaggcac
     5941 ctgcccatga tcgcagccct cctgcacggc cgcactcatc tgaacttcca ggagttccgg
     6001 cagcagaacc acctggcctt cttcctgcat gtgctgggca tcctggagct gctgcagccg
     6061 cgtgtgttcc agagcgaaca ccagggggcg ctttgggact gcctgcgatc ctttatccgc
     6121 ctgctcctga actaccggaa gtcctcccgc cacctggctc ccttcattag caagttcgtt
     6181 cagttcatcc acaagtacgt gggctgcagc gcaccagcag ccgtggcctt cctgcagaag
     6241 cacgcagagc ccctccatga cctgtccttt gacaacagtg acctggtgat gttgaagtct
     6301 ttactggcag ggctcagcct gcccagccgg gatgggagaa ctgaccaagg cctggatgag
     6361 gaaggcgaag atgagcgttc ggccggctcc ctacccctgg tcagtgtctc cctctccacc
     6421 ccactgactg tagccgacgt ggctcctcac atgaagaggc tgtcccgggg ccgggctgtt
     6481 gaggatgtgc tcgagaccct gagtgacata gacgagatgt cgcggcggag acctgaggtc
     6541 ctgggcttct tctcgaccaa cttgcagcgg ctgatgagct cagcggagga gtcctgccgc
     6601 aacctggcct tcagcctagc actgcgctcc attcagaaca accccagcat cgctgctgac
     6661 tttctgccca ccttcatgta ctgcctgggc agcagagact ttgaggtggt acagacagcc
     6721 ctcaggaacc tgccagagta caccctgctc tgccaagagc acgcggctgt cctgctgcac
     6781 agagccttcc ttgtgggcgt gtacggccag attgacacca gcgcccagat atcagaggcc
     6841 ctgaagatcc tacacatgga ggctgtgatg tgaactgctc ctgttgccag gcctccaagc
     6901 cacaccagcg agacagcctg tccaagacac acctgccctg gacagcctcg ccctgagccc
     6961 cttgaggctg gagcatccac tggtactgaa agtcctcttg agtgctcctc ctgtcctgga
     7021 gtcacaggag atatgatgga gagaggctgt tctgccagca aggcaggcgc actgagggca
     7081 gtttcaatga agctcgagtg cctgtg
//
