LOCUS       NM_023547               1191 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus INO80 complex subunit B (Ino80b), mRNA.
ACCESSION   NM_023547
VERSION     NM_023547.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1191)
  AUTHORS   Yang,G., Xin,Q., Feng,I., Wu,D. and Dean,J.
  TITLE     Germ cell-specific eIF4E1b regulates maternal mRNA translation to
            ensure zygotic genome activation
  JOURNAL   Genes Dev 37 (9-10), 418-431 (2023)
   PUBMED   37257918
REFERENCE   2  (bases 1 to 1191)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 1191)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 1191)
  AUTHORS   Min,J.N., Tian,Y., Xiao,Y., Wu,L., Li,L. and Chang,S.
  TITLE     The mINO80 chromatin remodeling complex is required for efficient
            telomere replication and maintenance of genome stability
  JOURNAL   Cell Res 23 (12), 1396-1413 (2013)
   PUBMED   23979016
REFERENCE   5  (bases 1 to 1191)
  AUTHORS   Miyako,K., Cobb,L.J., Francis,M., Huang,A., Peng,B., Pintar,J.E.,
            Ariga,H. and Cohen,P.
  TITLE     PAPA-1 Is a nuclear binding partner of IGFBP-2 and modulates its
            growth-promoting actions
  JOURNAL   Mol Endocrinol 23 (2), 169-175 (2009)
   PUBMED   19095771
  REMARK    GeneRIF: Results suggest that the growth-promoting role of IGFBP-2
            in prostate cancer is inhibited by its intracellular interaction
            with PAPA-1.
REFERENCE   6  (bases 1 to 1191)
  AUTHORS   Maita,H., Kitaura,H., Ariga,H. and Iguchi-Ariga,S.M.
  TITLE     CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative
            splicing
  JOURNAL   Exp Cell Res 303 (2), 375-387 (2005)
   PUBMED   15652350
REFERENCE   7  (bases 1 to 1191)
  AUTHORS   Kuroda,T.S., Maita,H., Tabata,T., Taira,T., Kitaura,H., Ariga,H.
            and Iguchi-Ariga,S.M.
  TITLE     A novel nucleolar protein, PAPA-1, induces growth arrest as a
            result of cell cycle arrest at the G1 phase
  JOURNAL   Gene 340 (1), 83-98 (2004)
   PUBMED   15556297
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC104324.21.
            
            On Feb 16, 2019 this sequence version replaced NM_023547.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058788.1, AK010946.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-109               AC104324.21        161552-161660       c
            110-302             AC104324.21        161126-161318       c
            303-421             AC104324.21        160848-160966       c
            422-591             AC104324.21        160535-160704       c
            592-1191            AC104324.21        158306-158905       c
FEATURES             Location/Qualifiers
     source          1..1191
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 35.94 cM"
     gene            1..1191
                     /gene="Ino80b"
                     /gene_synonym="2510009I23Rik; HMG1YL4; Hmga1l4; Papa1;
                     Znhit4"
                     /note="INO80 complex subunit B"
                     /db_xref="GeneID:70020"
                     /db_xref="MGI:MGI:1917270"
     exon            1..109
                     /gene="Ino80b"
                     /gene_synonym="2510009I23Rik; HMG1YL4; Hmga1l4; Papa1;
                     Znhit4"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..1128
                     /gene="Ino80b"
                     /gene_synonym="2510009I23Rik; HMG1YL4; Hmga1l4; Papa1;
                     Znhit4"
                     /note="high mobility group AT-hook 1-like 4; PAP-1 binding
                     protein; PAPA-1; PAP-1-associated protein 1; zinc finger
                     HIT domain-containing protein 4; zinc finger, HIT type 4"
                     /codon_start=1
                     /product="INO80 complex subunit B"
                     /protein_id="NP_076036.2"
                     /db_xref="CCDS:CCDS39530.1"
                     /db_xref="GeneID:70020"
                     /db_xref="MGI:MGI:1917270"
                     /translation="MSKLWRRGSTSGAMEAPEPGETLELSLAGAHGHGVHKKKHKKHK
                     KKHKKKHHQEEEAGPTLQTPAKPQLKLKIKLGGQVLGTKSVPTFTVIPEGPRSPSPLM
                     VVDNEEEPMEGVPLEQYRAWLDEDSNLSPSPLRDLPGDLEGQEEEEEQRWLDALEKGE
                     LDDNGDLKKEINERLLTARQRALLQKARSQPSPTLPLPVGGGCPAPALTEEMLLKREE
                     RARKRRLQAARRAEEHKNQTIERLTKTAAPSGRGGRGAARGERRGGRAAAPAPAPMVR
                     YCSGAQGSTLSFPPGVPTPTAVAQRPAPSGPAPRCSVPGCPHPRRYACSRTGQALCSL
                     QCYRINLQLRLGGPEGPGSPLLAT"
     exon            110..302
                     /gene="Ino80b"
                     /gene_synonym="2510009I23Rik; HMG1YL4; Hmga1l4; Papa1;
                     Znhit4"
                     /inference="alignment:Splign:2.1.0"
     exon            303..421
                     /gene="Ino80b"
                     /gene_synonym="2510009I23Rik; HMG1YL4; Hmga1l4; Papa1;
                     Znhit4"
                     /inference="alignment:Splign:2.1.0"
     exon            422..591
                     /gene="Ino80b"
                     /gene_synonym="2510009I23Rik; HMG1YL4; Hmga1l4; Papa1;
                     Znhit4"
                     /inference="alignment:Splign:2.1.0"
     exon            592..1191
                     /gene="Ino80b"
                     /gene_synonym="2510009I23Rik; HMG1YL4; Hmga1l4; Papa1;
                     Znhit4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1169..1174
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ino80b"
                     /gene_synonym="2510009I23Rik; HMG1YL4; Hmga1l4; Papa1;
                     Znhit4"
                     /note="hexamer: ATTAAA"
     polyA_site      1191
                     /gene="Ino80b"
                     /gene_synonym="2510009I23Rik; HMG1YL4; Hmga1l4; Papa1;
                     Znhit4"
                     /note="major polyA site"
ORIGIN      
        1 atgtcggctt gtgtcccgac agtttccagt cctctccctt tgcaggaccc catgagcaag
       61 ctgtggcggc gcgggagcac atctggggct atggaggccc ccgagccagg ggaaacgctg
      121 gagctgagcc tggcaggtgc ccacggccac ggagtacaca agaaaaaaca caagaaacat
      181 aaaaagaaac acaagaaaaa gcatcatcag gaagaggagg ccggaccgac gctgcagact
      241 cctgccaagc cccaacttaa acttaaaatc aagctgggtg gacaggtcct gggcaccaag
      301 agtgtcccca ctttcactgt gattcctgag gggcctcgct caccgtctcc cctgatggtg
      361 gtggataatg aagaggaacc tatggaaggc gtacctctgg agcagtaccg cgcctggctg
      421 gatgaagaca gtaatctgtc cccctcccca cttcgggacc tgccagggga tctggagggc
      481 caggaggaag aggaggaaca gagatggtta gacgccctgg agaagggaga gctggatgac
      541 aacggagacc tcaagaagga gatcaatgag cggctgctta cagcgagaca gcgagccctc
      601 ctccagaagg cgcggagcca gccgtccccg actctgcctc tgccagtggg tgggggctgc
      661 cctgcccctg ccctcaccga agagatgctg ctgaagcgtg aggagcgtgc acggaagcgg
      721 cggctgcagg cggcgaggag ggccgaggag cacaaaaatc agacaattga gcgcctcacc
      781 aagacggccg ctcctagcgg gcgtggaggg cgcggggcgg cgcggggcga gcggcgcgga
      841 ggacgggctg ctgccccggc ccctgcaccc atggtgcgct actgcagcgg ggcacagggc
      901 tccaccttgt cttttcctcc cggcgttccc acacccacgg cggtggcaca gcggcctgcc
      961 ccatcgggcc ccgctccacg atgctctgtc cccggctgcc cccacccgcg tcgttatgcc
     1021 tgctcccgca ccggccaggc cctttgcagc ctacagtgct accgcatcaa cctgcagcta
     1081 cggctgggag ggcccgaggg cccggggtcc ccactcctgg ccacctaaga cctctcccac
     1141 gccacattcc tgctgtctcc cccaccctat taaatttcgt acagtgcctc a
//
