LOCUS       NM_026597               1025 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus inka box actin regulator 1 (Inka1), mRNA.
ACCESSION   NM_026597 XM_486256
VERSION     NM_026597.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1025)
  AUTHORS   Yamada,S., Mizukoshi,T., Tokunaga,A. and Sakakibara,S.I.
  TITLE     Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal
            development
  JOURNAL   PLoS Genet 18 (10), e1010438 (2022)
   PUBMED   36301793
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1025)
  AUTHORS   Van Otterloo,E., Feng,W., Jones,K.L., Hynes,N.E., Clouthier,D.E.,
            Niswander,L. and Williams,T.
  TITLE     MEMO1 drives cranial endochondral ossification and palatogenesis
  JOURNAL   Dev Biol 415 (2), 278-295 (2016)
   PUBMED   26746790
REFERENCE   3  (bases 1 to 1025)
  AUTHORS   Shalom-Barak,T., Zhang,X., Chu,T., Timothy Schaiff,W., Reddy,J.K.,
            Xu,J., Sadovsky,Y. and Barak,Y.
  TITLE     Placental PPARgamma regulates spatiotemporally diverse genes and a
            unique metabolic network
  JOURNAL   Dev Biol 372 (1), 143-155 (2012)
   PUBMED   22967998
REFERENCE   4  (bases 1 to 1025)
  AUTHORS   Taher,L., Collette,N.M., Murugesh,D., Maxwell,E., Ovcharenko,I. and
            Loots,G.G.
  TITLE     Global gene expression analysis of murine limb development
  JOURNAL   PLoS One 6 (12), e28358 (2011)
   PUBMED   22174793
REFERENCE   5  (bases 1 to 1025)
  AUTHORS   Reid,B.S., Sargent,T.D. and Williams,T.
  TITLE     Generation and characterization of a novel neural crest marker
            allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube
            closure
  JOURNAL   Dev Dyn 239 (4), 1188-1196 (2010)
   PUBMED   20175189
  REMARK    GeneRIF: Consistent with expression of Inka1 in tissues of the
            developing head during neurulation, a low percentage of Inka1(-/-)
            mice show exencephaly while the remainder are viable and fertile.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL731808.26.
            
            On Jan 23, 2023 this sequence version replaced NM_026597.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK076092.1, AK020090.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164140, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-183               AL731808.26        89254-89436         c
            184-1025            AL731808.26        87780-88621         c
FEATURES             Location/Qualifiers
     source          1..1025
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 59.07 cM"
     gene            1..1025
                     /gene="Inka1"
                     /gene_synonym="6230427J02Rik; Fam212a"
                     /note="inka box actin regulator 1"
                     /db_xref="GeneID:68176"
                     /db_xref="MGI:MGI:1915426"
     exon            1..183
                     /gene="Inka1"
                     /gene_synonym="6230427J02Rik; Fam212a"
                     /inference="alignment:Splign:2.1.0"
     CDS             133..981
                     /gene="Inka1"
                     /gene_synonym="6230427J02Rik; Fam212a"
                     /note="protein FAM212A; MInca; family with sequence
                     similarity 212, member A; induced in neural crest by
                     AP2-alpha protein homolog; inca"
                     /codon_start=1
                     /product="PAK4-inhibitor INKA1"
                     /protein_id="NP_080873.2"
                     /db_xref="CCDS:CCDS52919.1"
                     /db_xref="GeneID:68176"
                     /db_xref="MGI:MGI:1915426"
                     /translation="MHSARLDSFLSQLRWELLCARDTGSPPMSGPLQPKPRTDQNVQP
                     KRQFRASDVLEEDSVCCVEEEEEEGLVAEDKGLPLGCPREHALDWDSGFSEVSGSTWR
                     EEEPSVPQRQAPRERPPHSQRFSVSDIPMRSRAAVTNIPPAHRPRPKSTPDACLEHWQ
                     GLEAEDWTAALLNRGRSRQPLVLGDNCFADLVHNWMELPEATSEGSDGDVPRARARPP
                     QFLLGLSEQLRRRLARARRTAMASKRLSCPPRSEPDLPADISRFAALMNCRSRQPIIY
                     NDVSYL"
     exon            184..1025
                     /gene="Inka1"
                     /gene_synonym="6230427J02Rik; Fam212a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1004..1009
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Inka1"
                     /gene_synonym="6230427J02Rik; Fam212a"
                     /note="hexamer: AATAAA"
     polyA_site      1025
                     /gene="Inka1"
                     /gene_synonym="6230427J02Rik; Fam212a"
                     /note="major polyA site"
ORIGIN      
        1 aaggagcctt agagtaaggc aagggtgagg acgccaccac ccgcgggccg acccggccca
       61 ctctgcgccg ctcccgcggg tgatcggcgg gtgagccggc cgacctggag agtgtacagc
      121 accagcacca gcatgcacag cgctcggctt gacagcttcc tgagccagct ccgctgggaa
      181 ctgttgtgtg ctcgggacac aggctcacct ccaatgtctg gcccactgca accaaaaccc
      241 agaactgatc aaaatgtaca gccaaagcgc cagttcaggg cctcggatgt tttggaagag
      301 gactctgtct gctgtgtaga agaggaagag gaggaaggct tggtagcaga agacaagggt
      361 ttacccttgg gatgtcctag ggagcatgct ctagactggg actctggctt ctccgaggtg
      421 tcaggcagta catggcgaga ggaagagccg tctgtacccc agcgccaagc acctcgagaa
      481 cgtccacctc atagccagcg tttctcagtc agtgacattc ctatgcgcag tagggcagct
      541 gtaaccaaca tacctcctgc ccaccgtccg aggcccaagt ccaccccaga tgcttgcctg
      601 gaacattggc agggattgga agcagaggac tggacggcag ccctgctgaa caggggccgc
      661 agtcggcagc ccctggtgct aggggataac tgttttgctg atttagttca caattggatg
      721 gagttgcctg aagcaaccag tgaggggagt gatggagatg taccccgagc acgggctcga
      781 ccccctcagt tcctgcttgg tctctctgag cagctacggc gtaggctggc cagggctcga
      841 cggacagcta tggcaagcaa gaggttgtcc tgcccacctc gctcagaacc tgacctgcct
      901 gcagacatct cacgatttgc agccctcatg aactgtcgaa gtcgccaacc tattatctac
      961 aatgatgtca gctacctctg accctgcccc tccagctagg gacaataaag gctttttttc
     1021 ctaaa
//
