LOCUS       NM_133976                915 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus IMP3, U3 small nucleolar ribonucleoprotein (Imp3),
            mRNA.
ACCESSION   NM_133976
VERSION     NM_133976.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 915)
  AUTHORS   Zhou,X., Ye,Q., Zheng,J., Kuang,L., Zhu,J. and Yan,H.
  TITLE     IMP3 promotes re-endothelialization after arterial injury via
            increasing stability of VEGF mRNAhv
  JOURNAL   J Cell Mol Med 26 (7), 2023-2037 (2022)
   PUBMED   35315195
REFERENCE   2  (bases 1 to 915)
  AUTHORS   Ueki,A., Shimizu,T., Masuda,K., Yamaguchi,S.I., Ishikawa,T.,
            Sugihara,E., Onishi,N., Kuninaka,S., Miyoshi,K., Muto,A.,
            Toyama,Y., Banno,K., Aoki,D. and Saya,H.
  TITLE     Up-regulation of Imp3 confers in vivo tumorigenicity on murine
            osteosarcoma cells
  JOURNAL   PLoS One 7 (11), e50621 (2012)
   PUBMED   23226335
  REMARK    GeneRIF: Imp3 as a key regulator of stem-like tumorigenic
            characteristics in osteosarcoma cells
REFERENCE   3  (bases 1 to 915)
  AUTHORS   Granneman,S., Gallagher,J.E., Vogelzangs,J., Horstman,W., van
            Venrooij,W.J., Baserga,S.J. and Pruijn,G.J.
  TITLE     The human Imp3 and Imp4 proteins form a ternary complex with
            hMpp10, which only interacts with the U3 snoRNA in 60-80S
            ribonucleoprotein complexes
  JOURNAL   Nucleic Acids Res 31 (7), 1877-1887 (2003)
   PUBMED   12655004
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC009145.1.
            
            On Apr 6, 2007 this sequence version replaced NM_133976.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC009145.1, BG870042.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-915               BC009145.1         4-918
FEATURES             Location/Qualifiers
     source          1..915
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 30.53 cM"
     gene            1..915
                     /gene="Imp3"
                     /gene_synonym="1190002L16Rik"
                     /note="IMP3, U3 small nucleolar ribonucleoprotein"
                     /db_xref="GeneID:102462"
                     /db_xref="MGI:MGI:1916119"
     exon            1..899
                     /gene="Imp3"
                     /gene_synonym="1190002L16Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             8..562
                     /gene="Imp3"
                     /gene_synonym="1190002L16Rik"
                     /note="U3 snoRNP protein IMP3; U3 snoRNP protein 3
                     homolog; IMP3, U3 small nucleolar ribonucleoprotein,
                     homolog"
                     /codon_start=1
                     /product="U3 small nucleolar ribonucleoprotein protein
                     IMP3"
                     /protein_id="NP_598737.1"
                     /db_xref="CCDS:CCDS23213.1"
                     /db_xref="GeneID:102462"
                     /db_xref="MGI:MGI:1916119"
                     /translation="MVRKLKFHEQKLLKQVDFLNWEVTDHNLHELRVLRRYRLQRREE
                     YTRYNQLSRAVRELARRLRDLPERDPFRVRASAALLDKLYAMGLVPTRGSLELCDSVS
                     ASSFCRRRLPTLLLKLRMAQHLQAAVAFVEQGHVRVGPDVVTDPAFLVTRSMEDFVTW
                     VDSSKIKRHVLEYNEERDDFDLDA"
     regulatory      868..873
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Imp3"
                     /gene_synonym="1190002L16Rik"
                     /note="hexamer: AATAAA"
     polyA_site      899
                     /gene="Imp3"
                     /gene_synonym="1190002L16Rik"
                     /note="major polyA site"
ORIGIN      
        1 ctccatcatg gtgcggaagc ttaagttcca cgagcagaag ctgctgaaac aggtggactt
       61 cctaaactgg gaagtcaccg accacaacct ccacgaactg cgtgtgctgc ggcggtaccg
      121 gctgcagcgg cgcgaggagt acacgcgcta caaccagctg agccgagcgg tgcgcgagct
      181 ggcgcggcgc ctgcgcgacc tgccggaacg cgacccattc cgcgtgcgcg cctcggcggc
      241 gctgttggac aagctgtacg ctatgggcct ggtgcccacg cgcggctcac tggaactctg
      301 cgactccgtc tcggcctcgt ccttctgccg ccgccgcttg cctactttgc tcctcaagct
      361 acgcatggcg cagcatctcc aagctgctgt ggcttttgtg gagcagggtc atgtccgcgt
      421 gggcccagac gtggtcactg atcccgcctt tctcgtcact cgcagcatgg aggactttgt
      481 cacctgggtg gactcatcca agatcaagcg gcacgtgttg gagtacaatg aggagcgcga
      541 tgactttgat ctagatgcct agcgagtctt cttgtcctgg cttctcagct acaggtcact
      601 gaaccgggga tggggaggat tgccccggtg tactgggaat ttttcctaga atttggactg
      661 acaattaagt gactgtgtct tgagagacag tgggaagcag ttttgtaccg cactggggat
      721 tgctagcttc ttgtgcctta aactttgtgg tgtagaagca ggaatgttac ctcttcccct
      781 ttgctttcat cttgaaatag gaccgtctgg atggagagtt tgagttcagt atatttatat
      841 cgtttaaaga aaccctttcc taatgccaat aaatgtccca ccgacgttgt ttaagtgcaa
      901 aaaaaaaaaa aaaaa
//
